• Journal of Chest Surgery
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• 제51권6호
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• pp.419-422
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• 2018

Hemangioendothelioma is a rare vascular tumor with involvement of the liver, brain, long bones, and lung. Among the 6 histological subtypes, epithelioid hemangioendothelioma (EHE) is the most aggressive. Its occurrence in the mediastinum is quite rare, and very few cases have been documented. The reported cases in the literature have described difficulties in the preoperative diagnosis due to the unusual histological appearance of the tumor. Immunohistochemistry remains the mainstay for a definitive diagnosis. Due to its low incidence, there is no standard treatment for mediastinal EHE, but curative resection is the preferred treatment option where possible, with chemotherapy used as an adjuvant treatment or in cases of widespread inoperable disease. The present case study describes an aggressive EHE occurring in an 18-year-old woman in the anterior mediastinum.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2000년도 하계종합학술대회 논문집(5)
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• pp.113-116
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• 2000

In this paper presents the portable wireless ECG data detection and diagnosis system based on discreet wavelet transform. An algorithm based on wavelet transform suitable for real time implementation has been developed in order to detect ECG characteristics. In particular, QRS complex, S and T waves may be distinguished form noise, baseline drift or artifacts. Proposed telemetry system that a transmitting media using radio frequency(RF) for the middle range measurement of the physiological signals and receiving media using optical for electromagnetic interference problem. A standard hi-directional serial communication interface between the telemetry system and a personal computer or laptop, allows read-time controlling, diagnosing and monitoring of system. A portable telemetry system within a size. of 65${\times}$125${\times}$45mm consists of three parts: a digital signal processing part for physiological signal detect or diagnose, RF transmitter for data transfer and a optical receiver for command receive. Advantages of proposed telemetry system is wireless middle range(50m) FM transmission, reduce electromagnetic interference to a minimum. which enables a comfortable diagnosis system at home.

• Journal of Interdisciplinary Genomics
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• 제3권1호
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• pp.1-6
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• 2021

Maturity-onset diabetes of the young (MODY) is characterized by a heterogeneous group of monogenic diabetes. MODY has autosomal dominant inheritance, a primary defect in pancreatic β-cell, and an early onset. Discriminating MODY from type 1 or type 2 diabetes is often challenging at first. To date, 14 different disease causing mutations have been identified in MODY patients worldwide. Targeted DNA sequencing is the gold standard to diagnose MODY and their asymptomatic relatives. Next-generation sequencing may help successfully to diagnose MODY patients and identify new MODY genes. In this review, the current perspectives on diagnosis and treatment of MODY and discrepancy in the disease-causing mutations between the Asian and Caucasian patients with MODY are summarized.

• 조명전기설비학회논문지
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• 제24권12호
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• pp.147-155
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• 2010

We studied on performance improvement of TTM(TI21 Test Meter) that is test and diagnosis devices for jointless audio frequency track circuit on Korean electric railway TI21 standard. Upgraded devices is AD-TTM(Advanced TI21 Test Meter). This can measure alternating frequency USB(Upper signal band) and LSB(Lower signal band). In the audio frequency track circuit, ${\pm}17[Hz]$ of nominal frequency are demodulated and supplied to track relay through AND gate. It is important that measurement function which is error between USB and LSB. Need of AD-TTM will stand out in the electric railway system because this is simple and accurate rather than the former device.

• Clinical and Experimental Pediatrics
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• 제50권8호
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• pp.726-731
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• 2007

This review describes the wide spectrum of paroxysmal events during sleep in infancy and childhood. The differential diagnosis between sleep-related non-epileptic paroxysmal events and epileptic seizures is difficult in special occasions. The nocturnal frontal lobe seizure and of the more common nonepileptic paroxysmal events during sleep are described. The main differentiating features characterizing parasomnias are: onset in early childhood, rare episodes of long duration, relatively lower frequency per night, absence of stereotypy, gradual disappearance of older age. Video-polysomnography is the gold standard to diagnosing and differentiating parasomnias from nocturnal frontal lobe seizures.

• Translational and Clinical Pharmacology
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• 제26권3호
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• pp.111-114
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• 2018

Adding to the complexity of caring for critically ill patients is the fact that many of them have a creatinine clearance that exceeds $130mL/min/1.73m^2$. This phenomenon, termed augmented renal clearance (ARC), has only recently been widely recognized and its pathogenesis remains incompletely understood. However, ARC has been shown to result in increased dose requirements for drugs that are primarily eliminated by renal excretion, including many antimicrobial agents and enoxaparin. Recognition of ARC is hampered by the fact that the standard creatinine-based equations used to estimate renal function are not accurate in this clinical setting and the diagnosis is best established using both serum and urine creatinine measurements to calculate clearance. So a high index of clinical suspicion and awareness is usually required before this step is taken to confirm the diagnosis of ARC.

• 한국가축번식학회지
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• 제14권3호
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• pp.165-173
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• 1990

A simple and sensitive microplate enzyme immunoassay(ELISA) was developed for progesterone, based on progesterone monoclonal antibody as anti-progesterone, horseradish peroxise(HRP) as enzyme-label and tetramethylbenzidine(TMB) as substrate. The assay has a sensitivity of 5pg-120pg/well and intra- and inter assay coefficients of variation for progesterone standard curve(0.1ng-3.2ng/ml) were ranged 4.4-10.6% and 5.-12.6%, respectively. They assay is performed in less than two hours and provide reliable values to differentiate among samples from day 0(A.I.), day 14 and day 19. The discriminatory levels for early pregnancy diagnosis are [>10ng(day 19) & decreasing rate <1.5 : pregnancy] and [ 7ng & decreasing rate 1.5 : non-pregnancy]. The accuracy of the pregnancy diagnosis for cows classified as positive(pregnancy) and negative(non-pregnancy) were 96% and 100%, respectively.

• Tuberculosis and Respiratory Diseases
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• 제83권2호
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• pp.122-131
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• 2020

Hypersensitivity Pneumonitis (HP) one of the most common interstitial lung diseases (ILDs) is characterized by exposure to an inhaled inciting antigen that leads to a host immunologic reaction determining interstitial inflammation and architectural distortion. The underlying pathogenetic mechanisms are unclear. The absence of international shared diagnostic guidelines and the lack of a "gold-standard" test for HP combined with the presence of several clinical and radiologic overlapping features makes it particularly challenging to differentiate HP from other ILDs, also in expert contests. Radiology is playing a more crucial role in this process; recently the headcheese sign was recognized as a more specific for chronic-HP than the extensive mosaic attenuation. Several classification proposals and diagnostic models have been advanced by different groups, with no prospective validation. Therapeutic options for HP have been limited to antigen avoidance and immunosuppressant drugs over the last decades. Several questions about this condition remain unanswered and there is a need for more studies.

• 한국정밀공학회지
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• 제15권4호
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• pp.105-110
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• 1998

In this study, statistical and neural network methods were used to recognize the cutting tool states. This system employed the tool dynamometer and cutting force signals which are processed from the tool dynamometer sensor using linear discriminent function. To learn the necessary input/output mapping for turning operation diagnosis, the weights and thresholds of the neural network were adjusted according to the error back propagation method during off-line training. The cutting conditions, cutting force ratios and statistical values(standard deviation, coefficient of variation) attained from the cutting force signals were used as the inputs to the neural network. Through the suggested neural network a cutting tool states may be successfully diagnosed.

• 대한치과교정학회지
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• 제35권2호
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• pp.91-105
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• 2005

기존의 2차원적 진단자료는 상의 확대 및 왜곡으로 인해 형태나 크기의 정량적 평가시 부적절한 결과를 야기할 수 있어 안면비대칭의 정확한 진단과 치료계획 수립을 위해서는 3차원영상 진단의 도입이 필요하다. 본 연구는 안면비대칭 진단시 3차원적 분석에 도움이 되는 기준자료를 얻고자 정상교합자를 대상으로 하악골 3차원 영상 계측항목의 평균값과 좌우차이의 정상범주를 알아보기 위하여 시행되었다 뚜렷한 안면비대칭을 보이지 않는 성인 정상교합자 남녀 30명씩 총 80명을 대상으로 두경부 전산화단층사진을 촬영한 후 컴퓨터프로그램을 이용한 각각의 단면 촬영영상 정보를 이용하여 3차원 입체영상을 재구성한 다음, 하악골 비대칭시 좌우차이를 보일 수 있는 계측항목으로 ramus length를 나타내는 5개 condylar neck length를 나타내는 1개, mandibular body length를 나타내는 8개 등 15개의 거리 계측항목과, gonial angle을 나타내는 4개. frontal ramal inclination을 나타내는 2개. lateral ramal inclination을 나타내는 2개 등 8개의 각도계측항목, 총 23개의 계측항목을 설정한 후, 좌측과 우측을 구분하여 컴퓨터 상에서 3차원계측치를 구하고 좌우차이값을 산출하였다. 본 연구결과 얻어진 정상교합자의 하악골 3차원영상 계측항목의 좌우차이값은 안면비대칭 환자의 진단 기준치로 유용하게 사용될 수 있을 것이다.