• 제목/요약/키워드: source separation

검색결과 453건 처리시간 0.03초

HI-$H_2O$ 기상 혼합물에서 Silica 막의 안정성 (Stability of a Silica Membrane in the HI-$H_2O$ Gaseous Mixture)

  • 황갑진;박주식;이상호;최호상
    • 멤브레인
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    • 제14권3호
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    • pp.201-206
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    • 2004
  • 열화학적 IS 공정에서 요오드화수소의 분해에 적용하기 위하여 화학증착법(CVD)으로 제조된 silica 막의 안정성을 HI-$H_2O$ 기상 혼합물에서 평가하였다. Si 원천으로 tetraethoxysilane을 사용하여 서로 다른 CVD 온도로 기공크기가 100 nm인 $\alpha$-alumina를 처리하였다. CVD온도는 $700^{\circ}C$, $650^{\circ}C$, $600^{\circ}C$이었다. $600^{\circ}C$에서 수행한 단일 성분의 투과 실험에서 측정한 막의 $H_2$/$N_2$ 선택도는 CVD 온도 $700^{\circ}C$의 M1 막은 43.2, $650^{\circ}C$의 M2 막은 12.6, $600^{\circ}C$의 M3 막은 8.7을 나타내었다. HI-$H_2O$ 기상 혼합물에서 안정성 실험은 $450^{\circ}C$에서 수행하였는데, CVD 온도 $650^{\circ}C$에서 처리된 막이 다른 온도에서 처리된 막보다 더 안정성이 더 좋은 결과를 얻었다.

플루오레신나트륨의 농도 범위 분석 (Analysis for Concentration Range of Fluorescein Sodium)

  • 이다애;김용재;윤기철;김광기
    • 대한의용생체공학회:의공학회지
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    • 제41권2호
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    • pp.67-74
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    • 2020
  • Brain tumors or gliomas are fatal cancer species with high recurrence rates due to their strong invasiveness. Therefore, the goal of surgery is complete tumor resection. However, the surgery is difficult to distinguish the border because tumors and blood vessels have the same color tone and shape. The fluorescein sodium is used as a fluorescence contrast agent for boundary separation. When the external light source is irradiated, yellow fluorescence is expressed in the tumor, which helps distinguish between blood vessels and tumor boundaries. But, the fluorescence expression of fluorescence sodium depends on the concentration of fluorescein sodium and such analytical data is insufficient. The unclear fluorescence can obscure the boundaries between blood vessels and tumors. In addition, reduce the efficiency of fluorescence sodium use. This paper proposes a protocol of concentration range for fluorescence expression conditions. Fluorescent expression was observed using a near-infrared (NIR) color camera with corresponding dilution using normal saline in 1 ml microtube. The flunoresence emission density range is 1.00 mM to 0.15 mM. The fluorescence emission begin to 1.00 mM and the 0.15 mM discolor. The discolor is difficult to fluorescence emission condition obserbation. Thus, the maximum density range of the bright fluoresecein is 0.15 mM to 0.30 mM. When the concentration range of fluorescein sodium is analyzed based on the gradient of fluorescence expression and the power measurement, the brightest fluorescence is expected to facilitate the complete resection of the tumor. For the concentration range protocol, setting concentration ranges and analyzing fluorescence expression image according to saturation and brightness to find optimal fluorescence concentration are important. Concentration range protocols for fluorescence expression conditions can be used to find optimal concentrations of substances whose expression pattern varies with concentration ranges. This study is expected to be helpful in the boundary classification and resection of brain tumors and glioma.

A SUPER-JUPITER MICROLENS PLANET CHARACTERIZED BY HIGH-CADENCE KMTNET MICROLENSING SURVEY OBSERVATIONS OF OGLE-2015-BLG-0954

  • SHIN, I.-G.;RYU, Y.-H.;UDALSKI, A.;ALBROW, M.;CHA, S.-M.;CHOI, J.-Y.;CHUNG, S.-J.;HAN, C.;HWANG, K.-H.;JUNG, Y.K.;KIM, D.-J.;KIM, S.-L.;LEE, C.-U.;LEE, Y.;PARK, B.-G.;PARK, H.;POGGE, R.W.;YEE, J.C.;PIETRUKOWICZ, P.;MROZ, P.;KOZLOWSKI, S.;POLESKI, R.;SKOWRON, J.;SOSZYNSKI, I.;SZYMANSKI, M.K.;ULACZYK, K.;WYRZYKOWSKI, L.;PAWLAK, M.;GOULD, A.
    • 천문학회지
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    • 제49권3호
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    • pp.73-81
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    • 2016
  • We report the characterization of a massive (mp = 3.9±1.4Mjup) microlensing planet (OGLE-2015-BLG-0954Lb) orbiting an M dwarf host (M = 0.33 ± 0.12M) at a distance toward the Galactic bulge of $0.6^{+0.4}_{-0.2}kpc$, which is extremely nearby by microlensing standards. The planet-host projected separation is a⊥ ~ 1.2AU. The characterization was made possible by the wide-field (4 deg2) high cadence (Γ = 6 hr–1) monitoring of the Korea Microlensing Telescope Network (KMTNet), which had two of its three telescopes in commissioning operations at the time of the planetary anomaly. The source crossing time t* = 16 min is among the shortest ever published. The high-cadence, wide-field observations that are the hallmark of KMTNet are the only way to routinely capture such short crossings. High-cadence resolution of short caustic crossings will preferentially lead to mass and distance measurements for the lens. This is because the short crossing time typically implies a nearby lens, which enables the measurement of additional effects (bright lens and/or microlens parallax). When combined with the measured crossing time, these effects can yield planet/host masses and distance.

N-propyl-N,N-dimethylethanolamine의 Phantom에서 Laser Induced Fluorescence의 스펙트라에 관한 연구 (A Study on Spectra of Laser Induced Flourescence in Phantom of N-propyl-N,N-dimethylethanolamine)

  • 김기준;이주호;이주엽;성완모
    • 한국응용과학기술학회지
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    • 제32권2호
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    • pp.330-338
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    • 2015
  • N-propyl-N,N-dimethylethanolamine의 산란혼탁매질에서 형광, 산란과 응집의 영향은 파장 과 산란된 형광세기로 나타내는데, laser induced fluorescence(LIF) 분광학에 의한 분자특성으로 나타난다. 산란매질에서 광학적 효과는 광학적 파라미터들(${\mu}_s$, ${\mu}_a$, ${\mu}_t$)에 의해 표현되고 응집은 고-액상 분리 공정에서 중요하게 활용되고 있다. 따라서 입자가 서로 접근될 때 콜로이드 입자들의 상호작용을 LIF와 응집효과로 분석하였다. Monte Carlo simuation과 실험으로 레이저 광원에서 검출기까지 거리의 함수에 의해 농도가 묽어짐에 따라 산란세기가 기하급수적으로 감소함을 알 수 있었다. 이는 유지화학, 생의학, 레이저 의학, 의공학 분야적용에 LIF와 입자이동 현상은 아주 적합한 모델 연구에 큰 도움이 될 것이다.

Simultaneous Determination of Five Porphyrins in Human Urine and Plasma Using High Performance Liquid Chromatography-Tandem Mass Spectrometry

  • Hur, Yeoun;Tae, Sookil;Koh, Yun-Joo;Hong, Sung-Hyun;Yoon, Young Ho;Jang, Haejong;Kim, Sooji;Kim, Kyeong Ho;Kang, Seung Woo;Lee, Youngshin;Han, Sang Beom
    • Mass Spectrometry Letters
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    • 제5권2호
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    • pp.42-48
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    • 2014
  • A specific and sensitive liquid chromatography-electrospray ionization tandem mass spectrometry method (LC-ESI-MS/MS) was developed and validated for the simultaneous quantification of porphyrins (coproporphyrin, pentacarboxylporphyrin, hexacarboxylporphyrin, heptacarboxylporphyrin, and uroporphyrin) in human plasma and urine. Acidified plasma samples and urine samples were prepared by using liquid-liquid extraction using ethyl acetate and protein precipitation with acetonitrile, respectively. The separation was achieved onto a Synergi Fusion RP column ($150mm{\times}2.0mm$, $4{\mu}m$) with a gradient elution of mobile phase A (0.1% formic acid in 2 mmol/L ammonium acetate, v/v) and mobile phase B (20% methanol in acetonitrile, v/v) at a flow rate of $450{\mu}L$/min. Porphyrins and the internal standard (IS), coproporphyrin I-$^{15}N_4$, were detected by a tandem mass spectrometer equipped with an electrospray ion source operating in positive ion mode. Multiple reaction monitoring (MRM) transitions of the protonated precursor ions and the related product ions were optimized to increase selectivity and sensitivity. The proposed method was validated by assessing selectivity, linearity, limit of quantification (LOQ), precision, accuracy, recovery, and stability. The calibration curves were obtained in the range of 0.1-100 nmol/L and the LOQs were estimated as 0.1 nmol/L for all porphyrins. Results obtained from the validation study of porphyrins showed good accuracy, precision, recovery, and stability. Finally, the proposed method was successfully applied to clinical studies on the autism spectrum disorder (ASD) diagnosis of 203 Korean children.

Preparation and characterization of protein isolate from Yellowfin tuna Thunnus albacares roe by isoelectric solubilization/precipitation process

  • Lee, Hyun Ji;Lee, Gyoon-Woo;Yoon, In Seong;Park, Sung Hwan;Park, Sun Young;Kim, Jin-Soo;Heu, Min Soo
    • Fisheries and Aquatic Sciences
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    • 제19권3호
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    • pp.14.1-14.10
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    • 2016
  • Isoelectric solubilization/precipitation (ISP) processing allows selective, pH-induced water solubility of proteins with concurrent separation of lipids and removal of materials not intended for human consumption such as bone, scales, skin, etc. Recovered proteins retain functional properties and nutritional value. Four roe protein isolates (RPIs) from yellowfin tuna roe were prepared under different solubilization and precipitation condition (pH 11/4.5, pH 11/5.5, pH 12/4.5 and pH 12/5.5). RPIs contained 2.3-5.0 % moisture, 79.1-87.8 % protein, 5.6-7. 4 % lipid and 3.0-3.8 % ash. Protein content of RPI-1 and RPI-2 precipitated at pH 4.5 and 5.5 after alkaline solubilization at pH 11, was higher than those of RPI-3 and RPI-4 after alkaline solubilization at pH 12 (P < 0.05). Lipid content (5.6-7.4 %) of RPIs was lower than that of freeze-dried concentrate (10.6 %). And leucine and lysine of RPIs were the most abundant amino acids (8.8-9.4 and 8.5-8.9 g/100 g protein, respectively). S, Na, P, K as minerals were the major elements in RPIs. SDS-PAGE of RPIs showed bands at 100, 45, 25 and 15 K. Moisture and protein contents of process water as a 2'nd byproduct were 98.9-99.0 and 1.3-1.8 %, respectively. Therefore, yellowfin tuna roe isolate could be a promising source of valuable nutrients for human food and animal feeds.

DRUM impactor를 이용한 대기 입자상 물질 중 원소성분의 입경분포 특성 : 제주도 고산지역의 2002년 봄철 (3.29-5.30) 측정 연구 (Size Distributions of Trace Elements in Airborn Particulates Collected using Drum impactor at Gosan, Jeju Island : Measurements in Springtime 2002)

  • 한진석;문광주;류성윤;안준영;공부주;홍유덕;김영준
    • 한국대기환경학회지
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    • 제20권4호
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    • pp.555-569
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    • 2004
  • Size -segregated measurements of aerosol composition using 8-stage DRUM impactor are used to determine the transport of natural and anthropogenic aerosols at Gosan site from 29 March to 30 May in 2002. Separation of ambient aerosols by DRUM impactor offers many Advantages over other standard filtration techniques. Some of the most important advantages are the ability to segregate into details by particle tire, to better preserve chemical integrity since the air stream doesn't pars through the deposit, to collect samples as a function of time, and to have a wide variety of impaction surfaces available to match analytical needs. Although the transport of Yellow sand is a well-known phenomenon in springtime, the result of measurement shows that not only soil dust but also anthropogenic aerosols, including sulfur, enriched trace metals such as Pb, Ni, Zn. Cu, Cr, As, Se, Br, are transported to Gosan in springtime. This study combines the size- and time-resolved aerosol composition measurements with isentropic, backward air-mass trajectories in order to identify some potential source regions of anthropogenic aerosols. As a result, during the NYS period, the average concentration of PM$_{10}$ was 46$\mu\textrm{g}$/㎥, Si, Al. S, Fe, Cl, K, Ca were higher than 1,000 ng/㎥ and Ti was about 100 ng/㎥. The concentrations of Zn, Mn, Cu. Pb, Br, Rb, V, Cr, Ni. At, Se ranged between 1 and 70 ng/㎥. More than 50% typical soil elements, tuck as Al, Si, Fe, Cd. Ti, Cr, Cu, Br. were distributed in a coarse particle range(5.0-12${\mu}{\textrm}{m}$). In other hand, anthropogenic pollutants, luck as S, N, Vi, were mainly distributed in a fine particle range (0.09-0.56${\mu}{\textrm}{m}$). During the YS period, PM$_{10}$ increased about 8 times than NYS period, and main soil elements, such as Al, Si, S, K, V, Mn, Fe also doubled in coarse particle range (1.15-12${\mu}{\textrm}{m}$). But Zn, As, Pb, Cu and Se, which distributed in the time aerosols (0.09-0.56${\mu}{\textrm}{m}$), were on the same level with or decreased than NYS period. Finally. except the YS Period, coarse particles (2.5-12${\mu}{\textrm}{m}$) are inferred to be influenced by soil, coal combustion, waste incineration, ferrous and nonferrous sources through similar pathways with Yellow Sand. But fine particles have different sources, such as coal combustion, gasoline vehicle, biomass burning, oil or coal combustion, nonferrous and ferrous metal sources, which are transported from China, Korea peninsula and local sources.ces.

객체기반 3차원 오디오 방송 시스템 설계 (The Design of Object-based 3D Audio Broadcasting System)

  • 강경옥;장대영;서정일;정대권
    • 한국음향학회지
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    • 제22권7호
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    • pp.592-602
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    • 2003
  • 본 논문은 오디오를 동반한 방송 서비스에 있어서 기존의 단순 청취형의 오디오 서비스에서 탈피한 대화형의 객체 기반 3차원 오디오 방송 시스템의 구조를 설명한다. 객체기반 3차원 오디오 방송 시스템은 3차원 오디오 입력부, 3차원 오디오 편집/제작부, 3차원 오디오 부호화부, 3차원 오디오 복호화부, 3차원 오디오 장면합성부 및 3차원 오디오 재생부로 구성된다. 오디오 입력부에서는 3차원 배경음 객체와 독립적인 오디오 객체들을 획득한다. 편집/제작부에서는 오디오 객체들에 대한 3차원 음상정위 및 오디오 이미지 생성을 위한 파라미터를 설정하고, 이들을 조합하여 3차원 오디오 장면을 편집/제작한다. 부호화부에서는 장면정보와 오디오 객체들을 부호화하고, 복호화부에서는 오디오 객체들을 복원하고 장면정보를 획득한다. 장면 합성부에서는 장면정보와 오디오 객체들을 이용하여 오디오 장면을 구성한다. 3차원 오디오 재생부에서는 3차원 오디오 객체들 재생하고, 사용자의 제어신호를 이용한 대화형 기능을 구현한다.

Consecutive automated production of carbon-11 labeled radiopharmaceuticals by sharing 11C-methylation reagent from one 11C-synthetic module

  • Park, Hyun Sik;Lee, Hong Jin;An, Hyun Ho;Moon, Byung Seok;Lee, Byung Chul;Kim, Sang Eun
    • 대한방사성의약품학회지
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    • 제2권2호
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    • pp.123-131
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    • 2016
  • Increasing clinical demand for carbon-11 labeled radiopharmaceuticals has triggered technological advances in fields of radiochemistry and automated modules. Even though carbon-11 has a short half-life ($t_{1/2}=20.4min$), the consecutive second production of carbon-11 labeled radiopharmaceutical in one $^{11}C$-synthetic module should be delayed at least over 4 h to avoid the high radiation exposure. We herein aimed to produce two different carbon-11 labeled radiopharmaceuticals ([$^{11}C$]PIB and [$^{11}C$]methionine) by sharing of [$^{11}C$]methylation source in one $^{11}C$-synthetic module. The synthesis of $^{11}C$-labeling reagents ($[^{11}C]CH_3I$ or $[^{11}C]CH_3OTf$) is fully automated using the commercial TRACERlab $FX_{C-pro}$ module and is readily adaptable to $^{11}C$-labeling reactor for [$^{11}C$]PIB as well as another $^{11}C$-labeling apparatus for [$^{11}C$]methionine via the three-way valve. After completing the [$^{11}C$]PIB production, the re-synthesized $[^{11}C]CH_3I$ was passed through the three-way valve connected the polyetheretherketone (PEEK) line and loaded into the C18 Sep-Pak cartridge including the methionine precursor. The labeled product [^${11}C$]methionine was purified by a simple cartridge separation and reformulated into saline. The radiochemical yield of [$^{11}C$]PIB and [$^{11}C$]methionine were $5.3{\pm}0.6%$ and $18.7{\pm}0.8%$ (n.d.c.), respectively, with over 97% of radiochemical purity. The specific activity of [$^{11}C$]PIB was over $110GBq/{\mu}mol$. Total production time of two radiopharmaceuticals needs about 2 h from $1^{st}$ beam irradiation including quality control tests. Final [$^{11}C$]PIB and [$^{11}C$]methionine were satisfied all quality control test standards.

생태계 탄소순환 이해를 위한 국내 토양호흡 연구의 고찰 (Discussion of Soil Respiration for Understanding Ecosystem Carbon Cycle in Korea)

  • 이재호;이준석;전영문;채남이;이재석
    • 생태와환경
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    • 제46권2호
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    • pp.310-318
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    • 2013
  • 육상생태계의 토양에는 대기의 약 2배에 해당하는 많은 양의 탄소를 가지고 있으며, 기후변화에 의한 기온 상승으로 대기로의 방출에 매우 취약한 상황에 놓여 있다. 한반도의 육상 생태계 토양탄소 수지의 변화예측을 위해 필연적으로 요구되는 다양한 생태계의 토양호흡 자료 수집을 위해 이용되는 방법론, 기기, 기기들 간의 오차, 시공간적인 불균일성, 결측 자료에 대한 보충 (gap filling), 발생원 별 구분 등에 대한 현 상황을 정리하고 그를 바탕으로 국내 토양호흡 연구의 문제점과 과제에 대해 고찰하였다. 결론적으로 국내의 토양호흡 연구는 기기 간 또는 방법들 간의 오차 보정이나 노력들이 매우 빈약하게 행해져 왔기 때문에 과거 및 현재 축적되는 자료의 품질은 거의 보정되지 않은 상태로 볼 수 있다. 이러한 문제점들이 해소되지 않고 지금까지와 같은 방식으로 토양호흡 자료가 축적된다면 그 활용성은 매우 낮을 수 밖에 없다. 또한 장기적인 자료 축적, 토양호흡 조절 메커니즘에 관한 조절 실험, 다양한 생태계, 토성, 토심 등에 대한 자료 역시 장래의 토양권 탄소 동태 변화를 모델 수단으로 예측하는 데에는 매우 중요한 요소이므로 토양호흡 자료 수집과 함께 수집되어야 할 것이다. 더불어 장기적인 측면에서 이러한 문제들이 연구자 간에 깊숙이 인식되어 보다 양질의 자료가 생산되도록 노력할 필요가 있다.