• The Korean Journal of Physiology and Pharmacology
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• 제7권6호
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• pp.357-362
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• 2003

Carbon monoxide (CO) is low molecular weight oxide gas that is endogenously produced under physiological conditions and interacts with another gas, nitric oxide (NO), to act as a gastrointestinal messenger. The aim of this study was to determine the effects of exogenous CO on L-type calcium channel currents of human jejunal circular smooth muscle cells. Cells were voltage clamped with 10 mM barium ($Ba^{2+}$) as the charge carrier, and CO was directly applied into the bath to avoid perfusion induced effects on the recorded currents. 0.2% CO was increased barium current ($I_{Ba}$) by $15{\pm}2$% ($mean{\pm}S.E.$, p<0.01, n=11) in the cells. To determine if the effects of CO on barium current were mediated through the cGMP pathway, cells were pretreated with 1-H-[1,2,4]oxadiazolo[4,3,-a]quinoxalin-1-one (ODQ, $10{mu}M$), a soluble guanylyl cyclase inhibitor, and exogenous CO (0.2%) had no effect on barium currents in the presence of ODQ ($2{\pm}1$% increase, n=6, p>0.05). CO mediates inhibitory neurotransmission through the nitric oxide pathway. Therefore, to determine if the effects of CO on L-calcium channels were also mediated through NO, cells were incubated with $N^G-nitro-L-arginine$ (L-NNA, 1 mM), a nitric oxide synthase inhibitor. After L-NNA pretreatment, 0.2 % CO did not increase barium current ($4{\pm}2$% increase, n=6, p>0.05). NO donor, SNAP ($20{\mu}M$) increased barium current by $13{\pm}2$% (n=6, p<0.05) in human jejunal smooth muscle cells. These data suggest that CO activates L-type calcium channels through NO/cGMP dependant mechanism.

• 한국공간구조학회논문집
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• 제2권4호
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• pp.61-76
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• 2002

The structure system that is discreterized by continuous shells is usually used to make a large space structures and these structures show the collapse mechanisms that are captured at over the limit load, and snap-through and bifurcation are most well known of it. For the collapse mechanism, rise-span ratio, element stiffness and load mode are main factor, which it give an effect to unstable behavior. Moreover, resist force of structure can be reduced by initial condition and initial imperfection significantly. In order to investigate the instability of shell structures, the finite deformation theory can be applied and it becomes a nonlinear mathematics in which use equation of tangential stiffness incrementally. With an initial imperfection, using simple example and Flow Truss Dome, the buckling characteristics of space truss is main purpose of this paper, and unstable behavior is studied by proposed the numerical method. Also, by using MIDAS, this research work analyzes displacements and inner forces as the design load of model, and the ratio of buckling load of design load is investigated.

• 한국운동역학회지
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• 제20권1호
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• pp.49-55
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• 2010

The purpose of the study was to analyze kinetic factors required to the three-point jump shot of the basketball games through 3-D analysis and ground reaction force(GRF) analysis. Six university male players participated in this study. The results of the study were showed that (1) resultant velocity in the center of mass(COM) was $0.84{\pm}0.27\;m/s$ since a player didn't shot a ball in the highest peak and shot ball at the moment of going up forward and vertical movement. Therefore, it is necessary to find a proper timing to shot a ball; (2) the angular velocity was largely increased in upper arm and fore arm out of the upper-limb segments and the hands had the largest angular velocity since the body is in a fixed situation and angular speed is rapidly increased by the wrist' snap with the rapid movement of upper arm and forearm at the time of release a ball; (3) it is judged that a player can shot a ball at the accurate and high release point when the player collects power vertically to the maximum by keeping GRF to the right and the rear in a proper way and by keeping the body's balance so that a large power may not be dispersed.

• 한국강구조학회 논문집
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• 제18권4호
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• pp.427-436
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• 2006

고전 좌굴 이론의 경우 좌굴 발생전 아치의 거동을 선형으로 가정하며, 전좌굴 변형을 무시한다. 이러한 가정은 비대칭 좌굴이 발생하는 깊은 아치의 경우 타당한 것으로 알려져 있다. 하지만 아치의 라이즈가 낮아지는경우 전좌굴 발선형성은 무시할 수 없으며, 비대칭 좌굴 강도보다 대칭 좌굴 강도가 낮아져 아치는 대칭좌굴에 의해 강도가 결정될 수 있다. 본 연구는 아치의 비선형 지배 미분 방정식을 이용하여 양단 힌지를 갖는 낮은 포물선 아치의 거동에 관한 연구를 수행하고 이러한 결과를 유한 요소 해석을 이용하여 검증하였다. 마지막으로 양단 힌지를 갖는 낮은 포물선 아치의 대칭 좌굴 강도에 관한 근사식을 제안하였다.

• Structural Engineering and Mechanics
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• 제58권2호
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• pp.327-345
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• 2016

Many experimental and analytical studies have been conducted with beam-column subassemblages composed of a two-span beam to investigate the progressive collapse resistance of RC frames. Most study results reveal a strength-decreased transition phase in the nonlinear static load-deflection curve, which may induce dynamic snap-through response and increase the chord rotation demand for effective catenary action (ECA). In this study, the nonlinear static response is idealized as a piecewise linear curve and analytical pseudo-static response is derived for each linearized region to investigate the rotation demands for the ECA of the two-span RC beams. With analytical parameters determined from several published test results, numerical analysis results indicate that the rotation demand of 0.20 rad recommended in the design guidelines does not always guarantee the ECA. A higher rotation demand may be induced for the two-span beams designed with smaller span-to-depth ratios and it is better to use their peak arch resistance (PAR) as the collapse strength. A tensile reinforcement ratio not greater than 1.0% and a span-to-depth ratio not less than 7.0 are suggested for the two-span RC beams bridging the removed column if the ECA is expected for the collapse resistance. Also, complementary pseudo-static analysis is advised to verify the ECA under realistic dynamic column loss even though the static PAR is recovered in the nonlinear static response. A practical empirical formula is provided to estimate an approximate rotation demand for the ECA.

• 한국멀티미디어학회논문지
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• 제19권3호
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• pp.557-566
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• 2016

Heart sounds generated by the beating heart and blood flow reflect the turbulence created when the heart valves snap shut. Cardiac diagnosis is typically started by an auscultation using a stethoscope, from which a medical doctor, depending on his hearing capabilities and training, listens and interprets the acoustic signal. This method of diagnostic is uncertain, mostly due to the fact that human ear loses the acoustic frequency sensitivity through the years. Even though an auscultation has some weaknesses like uncertainty, it is considered as a primary tool due to its simplicity. In this paper, heart murmur detection algorithm is proposed using time and frequency characteristics of heart sound. The propose heart murmur detection method adapted conventional primary heart sound detection method in time domain and modified spectral flatness method in frequency domain for detecting heart murmurs. From experimental results, it is confirmed that the proposed algorithm detect the heart murmurs efficiently.

• 한국소음진동공학회논문집
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• 제18권2호
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• pp.160-168
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• 2008

This paper presents the study on the stability of nonlinear oscillations of a thin cantilever beam subject to harmonic base excitation in vertical direction. Two partial differential governing equations under combined parametric and external excitations were derived and converted into two-degree-of-freedom ordinary differential Mathieu equations by using the Galerkin method. We used the method of multiple scales in order to analyze one-to-one combination resonance. From these, we could obtain the eigenvalue problem and analyze the stability of the system. From the thin cantilever experiment using foamax, we could observe the nonlinear modes of bending, twisting, sway, and snap-through buckling. In addition to qualitative information, the experiment using aluminum gave also the quantitative information for the stability of combination resonance of a thin cantilever beam under parametric excitation.

• 대한가정학회지
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• 제41권6호
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• pp.157-166
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• 2003

The purpose of this study was to provide information on how to improve the current design of infant coveralls through analysis of the design preferences of Korean consumer. In order to compile the information about preferences with the detail design of infant coveralls, a questionnaire was administered to mothers of 241 infants (aged under 36 months) living in Seoul, and analyzed using the SPSS WIN.10.0 program. The results of this study were as follows : 1) Results of buying conditions and design preference of infant coverall : To the question asking what kind of materials they preferred according to the season as material for infant coverall, the respondents preferred cotton hit as the materials for summer, but padding material for winter. The most favored design type were a flat collar, regular bodice type without cutting line, a raglan sleeves, snap front fastener, elastic band cuffs. 2) There is significant difference in preferred material and design among the month of age groups. 3) Analysis of the differences in preferred material and detail design according to gender In preferred material, it seemed as if girl baby group prefer cotton knit material, while boy baby group prefer padding material. There is definite difference in preferred neckline type, girl baby group prefer flat collar, while boy baby group prefer stand collar.

• 한국공간구조학회논문집
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• 제3권1호
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• pp.87-97
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• 2003

The structural system that discreterized from continuous shells is frequently used to make a large space structures. As well these structures show the unstable phenomena when a load level over the limit load, and snap-through and bifurcation are most well known of it. For the collapse mechanism, rise-span ratio, element stiffness and load mode are main factor, which it give an effect to unstable behavior. In our real situation, most structures have semi-rigid joint that has middle characteristic between pin and rigid joint. So the knowledge of semi-rigid joint is very important problem of stable large space structure. And the instability phenemena of framed space structures show a strong non-linearity and very sensitive behavior according to the joint rigidity For this reason In this study, we are investigating to unstable problem of framed structure with semi-rigidity and to grasp the nonlinear instability behavior that make the fundamental collapse mechanism of the large space frame structures with semi-rigid joint, by proposed the numerical analysis method. Using the incremental stiffness matrix in chapter 2, we study instability of space structures.

• Advances in aircraft and spacecraft science
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• 제2권3호
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• pp.345-365
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• 2015

This paper focuses on the design, fabrication, testing and analysis of a novel load-bearing element with energy dissipation capability. A single element comprises two von-Mises trusses (VMTs), which are sandwiched between two plates and connected to dashpots that stroke as the VMTs cycle between stable equilibrium states. The elements can be assembled in-plane to form a large plate-like structure or stacked with different properties in each layer for improved load-adaptability. Also introduced in the elements are pre-loaded springs (PLSs) that provide high initial stiffness and allow the element to carry a static load even when the VMTs cannot under harmonic disturbance input. Simulations of the system behavior using the Simscape environment show good overall correlation with test data. Good energy dissipation capability is observed over a frequency range from 0.1 Hz to 2 Hz. The test and simulation results show that a two layer prototype, having one soft VMT layer and one stiff VMT layer, can provide good energy dissipation over a decade of variation in harmonic load amplitude, while retaining the ability to carry static load due to the PLSs. The paper discusses how system design parameter changes affect the static load capability and the hysteresis behavior.