• Title/Summary/Keyword: small world network

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Reproduction of Epstein-Barr Virus Infection and Pathogenesis in Humanized Mice

  • Fujiwara, Shigeyoshi
    • IMMUNE NETWORK
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    • v.14 no.1
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    • pp.1-6
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    • 2014
  • Epstein-Barr virus (EBV) is etiologically associated with a variety of diseases including lymphoproliferative diseases, lymphomas, carcinomas, and autoimmune diseases. Humans are the only natural host of EBV and limited species of new-world monkeys can be infected with the virus in experimental conditions. Small animal models of EBV infection, required for evaluation of novel therapies and vaccines for EBV-associated diseases, have not been available. Recently the development of severely immunodeficient mouse strains enabled production of humanized mice in which human immune system components are reconstituted and express their normal functions. Humanized mice can serve as infection models for human-specific viruses such as EBV that target cells of the immune system. This review summarizes recent studies by the author's group addressing reproduction of EBV infection and pathogenesis in humanized mice.

An analysis on the web usage pattern graph using web users' access information (웹 이용자의 접속 정보 분석을 통한 웹 활용 그래프의 구성 및 분석)

  • Kim, Hu-Gon
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 2005.10a
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    • pp.422-440
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    • 2005
  • There are many kinds of research on web graph, most of them are focus on the hyperlinked structure of the web graph. Well known results on the web graph are rich-get-richer phenomenon, small-world phenomenon, scale-free network, etc. In this paper, we define a new directed web graph, so called the Web Usage Pattern Graph (WUPG), that nodes represent web sites and arcs between nodes represent a movement between two sites by users' browsing behavior. The data to constructing the WUPG, approximately 56,000 records, are gathered in the Kyungsung University. The results analysing the data summarized as follows: (i) extremely rich-get-richer phenomenon (ii) average path length between sites is significantly less than the previous one (iii) less external hyperlinks, more internal hyperlinks

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Interior management and e-business service platform of GMS SMEs

  • Yi, Hong;Zhou, Yue;Wang, Yuan-Liang;Liu, Qian-Hua
    • Proceedings of the Korea Society for Industrial Systems Conference
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    • 2007.02a
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    • pp.197-201
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    • 2007
  • Some problems such as scale is small, lacking fund and talent are exist in SMEs. How to improve the management & e-business level of SMEs become a world problem. To solve this problem, Yunnan SME Bureau request Yunnan Information & Telecom network (YNINFO Co,. Ltd.) to develop a ASP platform-- "Interior management for Yunnan SMEs and e-business service", the platform which is convenient in use and reasonable in price has been offered to SMEs by rental way.

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GENIIS, a New Hybrid Algorithm for Solving the Mixed Chinese Postman Problem

  • Choi, Myeong-Gil;Thangi, Nguyen-Manh;Hwang, Won-Joo
    • The Journal of Information Systems
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    • v.17 no.3
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    • pp.39-58
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    • 2008
  • Mixed Chinese Postman Problem (MCPP) is a practical generalization of the classical Chinese Postman Problem (CPP) and it could be applied in many real world. Although MCPP is useful in terms of reality, MCPP has been proved to be a NP-complete problem. To find optimal solutions efficiently in MCPP, we can reduce searching space to be small effective searching space containing optimal solutions. We propose GENIIS methodology, which is a kind of hybrid algorithm combines the approximate algorithms and genetic algorithm. To get good solutions in the effective searching space, GENIIS uses approximate algorithm and genetic algorithm. This paper validates the usefulness of the proposed approach in a simulation. The results of our paper could be utilized to increase the efficiencies of network and transportation in business.

Case study: Grigon Entertainment's success and failure

  • Yoo, Byung-Joon;Kim, Kwan-Soo;Lee, Joon-Hwan
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.4 no.4
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    • pp.71-88
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    • 2009
  • The Korean online gaming industry has seen rapid growth since the boom of information technology (IT) related industries, especially Internet and PC-bang or local area network (LAN) use, throughout the country. Online games are real-time games in which two or more players meet, compete, and cooperate in the same game space using the same communication network. Even though the growth rates of IT-related industries have recently slowed, the growth of the online gaming industry has increased, and Korean firms are expanding their businesses to countries all over the world. However, the online gaming industry is becoming an oligopoly, in which 4-5 leading companies occupy most online gaming markets. This situation presents a disadvantage to the Korean online gaming industry, since online players usually seek a diversity of online gaming contents and high quality online game services. Therefore, small- and medium-sized game developers must survive in this market by upgrading the quality of their online gaming services in an effort to provide differentiated goods and services in monopolistic competition markets. However, most venture companies in the online game industry, whether new or previously existing, are not able to obtain adequate financing. The objective of this paper is to examine the management environment for medium- and small-sized game developers in the Korean online gaming industry. By introducing the case of Grigon Entertainment, we try to identify the source of difficulty obtaining external financing for Korean venture firms in the online gaming industry.

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A study on the frequency sharing among broadcasting satellite networks (방송위성망간 주파수 공유에 관한 연구)

  • 박주홍;성향숙
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.29 no.2A
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    • pp.174-180
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    • 2004
  • The World Radiocommunication Conference in year of 2000 adopted new Plans as well as Lists for BSS and its feeder-link in the Regions 1 and 3, based on the new technical criteria such as small size of antenna and low satellite power. Since the new Plans and Lists were based on new technical criteria, ITU was requested to review the relevant regulatory procedures and sharing criteria of broadcasting satellite networks contained in Appendices 30 and 30A of Radio Regulations. Korean BSS network at 116$^{\circ}$E was chosen for the study and ITU S/W (MSPACEG) was used. We analyzed the interference effects from adjacent BSS networks to Korean BSS network using parameters of an antenna diameter and polarization of receiving earth station. The analysis shows that it is difficult to co-operate BSS networks both at 116$^{\circ}$E and 113$^{\circ}$E, however, it is possible to use small antenna (i.e. 45cm) in frequency sharing among BSS networks with 6$^{\circ}$ orbital separation.

The Development of Hybrid Power System using small Wind and Solar Energy (소형 풍력과 태양 에너지를 이용한 하이브리드 발전시스템 개발)

  • Kim, Min;Lee, Dong Heon;Jeong, Jae-Hoon;Park, Won-Hyeon;Byun, Gi-Sik;Kim, Gwan-Hyung
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2015.10a
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    • pp.250-251
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    • 2015
  • The situation requires a global alternative energy resources due to the lack of rapid consumption of fossil fuel and nuclear fuel that occurs in nature. There are a number of alternative energy research and development in the world today. Of which there is an existing wind power generation system has been developed into a large-scale systematic trend of small wind power systems have created a wind power generation system using a simple principle. Existing small wind turbine system is a situation that is in many places a deterioration odor problems and maintenance of power generation efficiency because it came to be developed systematically. In this paper, we developed a hybrid power system that can develop the solar energy at the same time as the increase in the small wind power generation efficiency and the system to develop that can efficiently maintain the hybrid power generation system through the network.

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Cloud-based Artificial Intelligence Fulfillment Service Platform in the Urban Manufacturing Cluster in Seoul (서울시 도심제조업 집적지에서의 Cloud 기반 인공지능 Fulfillment 서비스 Platform 연구)

  • Kim, Hyo-Young;Park, Dea-Woo
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.26 no.10
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    • pp.1447-1452
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    • 2022
  • Seoul Special City, one of the world's top 10 cities and Metro City, has traditional urban manufacturing industries such as printing, sewing, and mechanical metals. Small business owners in these manufacturing clusters have developed in the form of mutual assistance. Due to the nature of the agglomeration site, each process is handled by an individual company. It is difficult for relatively small business owners to prepare order processing services that provide real-time logistics movement information between processes. This paper collects and analyzes existing logistics data for smooth order and delivery of small business owners in package manufacturing and special printing fields We design an artificial intelligence Fulfillment Service Platform system with CRNN, k-NN, and ID3 Decision Tree Algorithm. Through this study, it is expected that it will greatly contribute to increasing sales and improving capabilities by allowing small business owners in integrated areas to use individual orders and delivery customized services through the Cloud network.

Co-Author Networks in Journal of the Korean Academy of Child and Adolescent Psychiatry (학술지 소아청소년정신의학의 공저 네트워크 분석)

  • Kim, Soungwan;Choi, Bum-Sung;Kim, Bongseog;Kim, Kyoung-Min
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.28 no.2
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    • pp.149-154
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    • 2017
  • Objectives: The purpose of this study is to analyze the co-author networks in the Journal of the Korean Academy of Child and Adolescent Psychiatry, a representative journal published by a branch of the domestic psychiatric academy, in order to present the current state of the co-authoring of and developments in child and adolescent psychiatry. Methods: We visualized and estimated the basic characteristics of the co-author networks shown by 564 authors who wrote 251 papers published in the Journal of the Korean Academy of Child and Adolescent Psychiatry between 2005 and 2015, in order to assess their network characteristics, author centrality, and relevance to research performance. Results: The co-author networks in the Journal of the Korean Academy of Child and Adolescent Psychiatry showed the characteristics of a small world and scale-free network. There was a correlation between the author centrality within the network and the research performance of the authors, but less correlation was shown between the centrality and mean paper citation counts. Conclusion: The network structure in the Journal of the Korean Academy of Child and Adolescent Psychiatry showed similarity to the co-authoring of other branches. However, given that the mean paper citation counts were less correlated with the author centrality than those in other branches, it may be necessary to promote an increase in the mean paper citation counts.

CHANGING THE ANIMAL WORLD WITH NIR : SMALL STEPS OR GIANT LEAPS\ulcorner

  • Flinn, Peter C.
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1062-1062
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    • 2001
  • The concept of “precision agriculture” or “site-specific farming” is usually confined to the fields of soil science, crop science and agronomy. However, because plants grow in soil, animals eat plants, and humans eat animal products, it could be argued (perhaps with some poetic licence) that the fields of feed quality, animal nutrition and animal production should also be considered in this context. NIR spectroscopy has proved over the last 20 years that it can provide a firm foundation for quality measurement across all of these fields, and with the continuing developments in instrumentation, computer capacity and software, is now a major cog in the wheel of precision agriculture. There have been a few giant leaps and a lot of small steps in the impact of NIR on the animal world. These have not been confined to the amazing advances in hardware and software, although would not have occurred without them. Rapid testing of forages, grains and mixed feeds by NIR for nutritional value to livestock is now commonplace in commercial laboratories world-wide. This would never have been possible without the pioneering work done by the USDA NIR Forage Research Network in the 1980's, following the landmark paper of Norris et al. in 1976. The advent of calibration transfer between instruments, algorithms which utilize huge databases for calibration and prediction, and the ability to directly scan whole grains and fresh forages can also be considered as major steps, if not leaps. More adventurous NIR applications have emerged in animal nutrition, with emphasis on estimating the functional properties of feeds, such as in vivo digestibility, voluntary intake, protein degradability and in vitro assays to simulate starch digestion. The potential to monitor the diets of grazing animals by using faecal NIR spectra is also now being realized. NIR measurements on animal carcasses and even live animals have also been attempted, with varying degrees of success, The use of discriminant analysis in these fields is proving a useful tool. The latest giant leap is likely to be the advent of relatively low-cost, portable and ultra-fast diode array NIR instruments, which can be used “on-site” and also be fitted to forage or grain harvesters. The fodder and livestock industries are no longer satisfied with what we once thought was revolutionary: a 2-3 day laboratory turnaround for fred quality testing. This means that the instrument needs to be taken to the samples rather than vice versa. Considerable research is underway in this area, but the challenge of calibration transfer and maintenance of instrument networks of this type remains. The animal world is currently facing its biggest challenges ever; animal welfare, alleged effects of animal products on human health, environmental and economic issues are difficult enough, but the current calamities of BSE and foot and mouth disease are “the last straw” NIR will not of course solve all these problems, but is already proving useful in some of these areas and will continue to do so.

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