• 대한산업공학회지
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• 제33권4호
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• pp.457-468
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• 2007

This paper proposes an adaptive moving average (A-MA) control chart with variable sampling intervals (VSI) for detecting shifts in the process mean. The basic idea of the VSI A-MA chart is to adjust sampling intervals as well as to accumulate previous samples selectively in order to increase the sensitivity. The VSI A-MA chart employs a threshold limit to determine whether or not to increase sampling rate as well as to accumulate previous samples. If a standardized control statistic falls outside the threshold limit, the next sample is taken with higher sampling rate and is accumulated to calculate the next control statistic. If the control statistic falls within the threshold limit, the next sample is taken with lower sampling rate and only the sample is used to get the control statistic. The VSI A-MA chart produces an 'out-of-control' signal either when any control statistic falls outside the control limit or when L-consecutive control statistics fall outside the threshold limit. The control length L is introduced to prevent small mean shifts from being undetected for a long period. A Markov chain model is employed to investigate the VSI A-MA sampling process. Formulae related to the steady state average time-to signal (ATS) for an in-control state and out-of-control state are derived in closed forms. A statistical design procedure for the VSI A-MA chart is proposed. Comparative studies show that the proposed VSI A-MA chart is uniformly superior to the adaptive Cumulative sum (CUSUM) chart and to the Exponentially Weighted Moving Average (EWMA) chart, and is comparable to the variable sampling size (VSS) VSI EWMA chart with respect to the ATS performance.

• 한국수산과학회지
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• 제41권6호
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• pp.493-504
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• 2008

In the seas around the Korean Peninsula, the seasonal cycle of zooplankton related to North Pacific regime shifts was investigated to understand the reaction of the ecosystem to climate change using long-term data on zooplankton biomass (1965-2000) and the abundance of four major zooplankton groups: copepods, amphipods, chaetognaths, and euphausiids (1978-2000). In general, the zooplankton biomass showed a large peak in spring and a small peak in autumnin Korean waters, but there was a slight difference in the peak time depending on the location and the period before and after the North Pacific regime shift. The zooplankton biomass showed conspicuous seasonal peaks in R-III (1990-2000) compared to R-I (1965-1976) and R-II (1977-1988), and the seasonal peak shifted from the autumn in R-II to the spring in R-III. The peak of copepods and euphausiids in abundance was from April to June, while chaetognaths peaked from August to October. We postulate that the time lag between the peaks for copepods and chaetognaths results from the predator-prey relationship. The regime shift in 1989 did not alter the seasonal cycle of the four major zooplankton groups, although it enhanced their production. The seasonal peaks of the four major zooplankton groups did not shift, while the seasonal peaks of the zooplankton biomass did shift. This was not only becausethe zooplankton biomass included other mesozooplankton groups but also because the abundance of the four major zooplankton groups increased significantly in spring.

• 노동경제논집
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• 제28권1호
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• pp.29-60
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• 2005

본 연구에서는 기업이 임금과 고용(근로자 수) 중 주로 어느 변수를 전략 변수로 사용하여 수요충격(demand shock)에 대응하는가를 연구한다. 또한 그러한 기업들의 적응 과정이 정(+)의 수요충격과 부(-)의 수요충격 사이에서 대칭적(symmetric)인가를 분석하며, 나아가 산업별 기업규모별, 그리고 노조 유무별로 그 적응패턴이 상이한가를 분석한다. 분석 결과를 요약하면 다음과 같다. 첫째, 전체적으로 기업들은 수요충격에 대해 임금조정보다는 고용조정으로 대응해 나가고 있다. 둘째, 전반적으로 임금이 경직적(rigid)으로 나타나는 이유는 주로 부(-)의 수요충격시 임금이 하방으로 경직적 (downward rigidity)이기 때문이며, 정(+)의 수요충격 시에는 다소 상향조정되는 것으로 나타난다. 셋째, 임금조정과 비교하여 고용조정은 정(＋)과 부(-)의 수요충격에 대해 대체로 대칭적이다. 넷째, 고용조정은 매출액 변동률에 대해 선형으로 나타나는 반면 임금조정은 비선형으로 나타난다. 정(+)의 수요충격시 임금은 그 충격의 강도가 상대적으로 약할 때는 반응을 하지 않다가 강도가 높아짐에 따라 상향조정의 폭도 점차 증가한다. 반대로 부(-)의 충격시 임금조정은 매출액 성장률의 오목함수로 표시된다. 다섯째, 노조기업은 비노조기업과 비교하여 수요충격에 대한 적응 수단으로 (특히 부(-)의 수요충격시) 고용보다는 임금을 주로 사용하는 것으로 나타났다.

• 한국동물위생학회지
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• 제43권1호
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• pp.39-44
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• 2020

The aim of this study is to investigate how the gut microbiome shifts when pigs were exposed with low concentrations of mycotoxins, deoxynivalenol (DON) and zearalenone (ZEN) in feed. Fifteen of pigs, 15 kg in weight which were negative for PRRSV and PCV2 were purchased, acclimatized until 20 kg in weight, and randomly divided into 3 groups; the DON group (DON treated), the ZEN group (ZEN treated) and the CTL (untreated negative control). DON and ZEN administered to each group for 30 days at 0.8 mg/kg (800 ppb) and 0.20 mg/kg (200 ppb) in feed, respectively. After extraction of microbial DNA from intestine and fecal samples, sequencing procedures were performed in the Ion PGM using an Ion 316 V2 chip and Ion PGM sequencing 400 kit. The results suggested that the bacterial communities in duodenum, jejunum and ileum of the DON and ZEN groups presented low-abundant OTUs compared with the CTL group. OTUs in cecum, colon and feces were determined more than in small intestine of all three groups. However, the CTL group yielded more OTUs than other two groups in inter-group comparison. It is not fully clarified how the richness and abundance in microbiome functions in the health condition of animals, however, the exposure to DON and ZEN has caused microbial population shifts representing microbial succession and changes following the diversity and abundance of porcine gut microbiome. The metabolomic analysis correlate with microbiome analysis is needed for further study.

• Journal of Biosystems Engineering
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• 제36권1호
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• pp.23-32
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• 2011

In this work, the finite element method was used to investigate the shifts of resonance frequencies and quality factor of whispering-gallery-mode (WGM) for an opto-fluidic ring resonator (OFRR) biosensor. To describe the near-field radiation transfer, the time-domain Maxwell's equations were employed and solved by using the in-plane TE wave application mode of the COMSOL Multiphysics with RF module. The OFRR biosensor model under current study includes a glass capillary with a diameter of 100 mm and wall thickness of 3.0 mm. The resonance energy spectrum curves in the wavelength range from 1545 nm to 1560 nm were examined under different biosensing conditions. We mainly studied the sensitivity of resonance shifts affected by changes in the effective thickness of the sensor resonator ring with a 3.0 mm thick wall, as well as changes in the refractive index (RI) of the medium inside ring resonators with both 2.5 mm and 3.0 mm thick walls. In the bulk RI detection, a sensitivity of 23.1 nm/refractive index units (RIU) is achieved for a 2.5 mm thick ring. In small molecule detection, a sensitivity of 26.4 pm/nm is achieved with a maximum Q-factor of $6.3{\times}10^3$. These results compare favorably with those obtained by other researchers.

• The Korean Journal of Physiology
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• 제17권1호
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• pp.1-11
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• 1983

1) 토끼동방결절의 작은 절편에 미세 전극 두개로 voltage clamp를 하고 과분극에 의하여 활성화되는 내향전류, $i_f$의 동력학적 성상을 분석하였다. 2) 전류 $i_f$는 $10^{-7}g/ml$ TTX와 2 mM $Mn^{2+}$의 존재하에서 과분극 pulse에 의하여 활성화되었으며 그 범위는 $-45\;mV{\sim}-75\;mV$였다. 전류의 크기와 시간경과는 막전압이 과분극될수록 커지고 빨라졌다. 3) Envelope test결과 $i_f$전류는 단일 gate에 의하여 지수합수적 (exponential)으로 조절됨을 보였다. 4) 2 mM의 $Ba^{2+}$에 의하여$i_f$전류의 크기는 감소하고 시간경과도 느려졌으며 반응속도상수와 gating molecule의 열리고 닫히는 반응계수(rate coefficient; ${\alpha}_s$, ${\beta}_s$)와 막전압 관계곡선을 과분극쪽으로 이동시켰다. 이러한 $Ba^{2+}$의 효과는 24 mM $K^+$에 의하여 일부 상쇄되었다.

• Journal of Magnetics
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• 제21권3호
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• pp.421-424
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• 2016

The purpose of this study is to evaluate an effectiveness of switching turbo direction to improve motion artifacts of small bowels and aorta. From June to October 2015, 60 patients suspected of having Crohn's disease were enrolled. The MR Enterography scans were performed using same protocol other than the turbo direction: with the Z phase encoding (group A) and with Y phase encoding (group B). Qualitative analysis of each group was performed to evaluate the effectiveness of switching turbo direction from Z to Y. As a result, the 5-point Likert scale for paired observers were $2.33{\pm}0.88$ for group A and $3.80{\pm}0.85$ for group B on dynamic contrast enhanced coronal images. In conclusion, group B is proved to be superior to group A and can lessen the motion artifacts derived from phase shifts.

• Journal of the Korean Data and Information Science Society
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• 제27권2호
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• pp.523-530
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• 2016

Most classical control charts assume that processes are serially independent, and autocorrelation among variables makes them unreliable. To address this issue, a variety of statistical approaches has been employed to estimate the serial structure of the process. In this paper, we propose a multioutput least squares support vector regression and apply it to construct a residual multivariate cumulative sum control chart for detecting changes in the process mean vector. Numerical studies demonstrate that the proposed multioutput least squares support vector regression based control chart provides more satisfying results in detecting small shifts in the process mean vector.

• Journal of applied mathematics & informatics
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• 제27권1_2호
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• pp.441-452
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• 2009

In this paper, a fifth order numerical method is presented for solving singularly perturbed differential-difference equations with negative shift. In recent papers the term negative shift has been using for delay. Similar boundary value problems are associated with expected first exit time problem of the membrane, potential in models for neuron and in variational problems in control theory. In the numerical treatment for such type of boundary value problems, first we use Taylor approximation to tackle terms containing small shifts which converts it to a boundary value problem for singularly perturbed differential equation. The two point boundary value problem is transformed into general first order ordinary differential equation system. A discrete approximation of a fifth order compact difference scheme is presented for the first order system and is solved using the boundary conditions. Several numerical examples are solved and compared with exact solution. It is observed that present method approximates the exact solution very well.

• 품질경영학회지
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• 제33권4호
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• pp.117-122
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• 2005

Variable sampling rate(VSR) scheme varies the sampling rate for the current sample depending on the previous value of the control statistic. In this paper, we propose EWMA control charts with variable parameter(VP) scheme, which allows both the sample rate(the sample size or the sampling interval) and the weight to vary. We investigate the effectiveness of the VP scheme relative to the fixed parameter(FP) scheme and the VSR scheme in EWMA control charts. It is shown that using the VP scheme gives some improvements to the ability in detecting small and moderate shifts in the process normal mean.