• Journal of Microbiology and Biotechnology
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• v.24 no.10
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• pp.1368-1376
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• 2014

This article focuses on the effects of glycine betaine on preventing caramelization, and increasing DCW and $\small{L}$-lysine production. The additional glycine betaine not only decreased the browning intensity (decreased 4 times), and the concentrations of 5-hydroxymethylfurfural (decreased 7.8 times) and furfural (decreased 12 times), but also increased the availability of glucose (increased 17.5%) for $\small{L}$-lysine production. The DCW and $\small{L}$-lysine production were increased by adding no more than 20 mM glycine betaine, whereas the DCW and $\small{L}$-lysine production were decreased with the reduction of pH values, although pH had a better response to prevent caramelization than did glycine betaine. For $\small{L}$-lysine production, the highest increase (40%) was observed on the media with 20 mM glycine betaine. The crucial enzymes in glycolysis and $\small{L}$-lysine biosynthesis pathway were investigated. The results indicated that additional glycine betaine increases the activity of enzymes in glycolysis, in contrast to the effect of pH. All the results indicated that glycine betaine can be used to prevent caramelization and increase the $\small{L}$-lysine production. By applying this strategy, glucose would not be have to be separated from the culture media during autoclaving so that factories can save production costs and shorten the fermentation period.

• Journal of Science Education
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• v.35 no.2
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• pp.119-126
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• 2011

The purpose of this study was to examine the effects of experimental learning using the small-scale chemistry (SSC) on high school students' academic achievement, scientific attitude and science-related attitude in high school chemistry I. For this study, two high school 2nd grade classes were divided into an experimental group and a control group. Experimental learning using the SSC in the experimental group, traditional experimental learning presented in the textbook in the control group were performed. The results showed that experimental learning using the SSC compared to traditional experimental learning was effective in improving academic achievement. The experimental learning also was effective in improving voluntary, patience, cooperativity in the scientific attitudes and social implications of science, attitude for science curriculum, attitude toward science in the science-related attitudes. Therefore, experimental learning using the SSC is necessary to actively utilize in high school chemistry curriculum.

• Journal of Biomedical Engineering Research
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• v.27 no.6
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• pp.376-383
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• 2006

Noise induced hearing loss (NIHS), the well-known occupational disease, is caused by continuous excessive noise. The prevention of NIHS is very important, because it is unrecoverable. There are some kinds of hearing protection device (HPD), and those are effective in preventing NIHS. But workers in noisy environment often resist to wearing them. Because they are ready - made products, so workers feel uncomfortable to wear. Also, they didn't maintain the conversation frequency range, so workers are hard to communicate in wearing them. To prevent hearing loss effectively, it is important that workers keep wearing HPD. Therefore, a HPD is needed to be comfortable to wear and be effective not only in hearing protection but also in preserving communication ability. So we proposed a custom - made hearing protection device in which a small acoustic filter is inserted. We designed several kinds of small acoustic filters and carried out some acoustic experiments for measuring characteristics of filters. We confirmed that acoustic transmission characteristic can be adjusted from experimental results using designed small acoustic filters. And we researched for the actual efficiency of a new developed custom - made hearing protection device using a small size acoustic filter. Also, we found out that workers are more satisfied with the new development than a former protection device from a workers' response.

• Journal of Biomedical Engineering Research
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• v.25 no.2
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• pp.97-102
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• 2004

We developed an x-ray cone-beam micro computed tomography (micro-CT) system for small-animal imaging. The micro-CT system consists of a 2-D flat-panel x-ray detector with a field-of-view (FOV) of 120${\times}$120 mm2, a micro-focus x-ray source, a scan controller and a parallel image reconstruction system. Imaging performances of the micro-CT system have been evaluated in terms of contrast and spatial resolution. The minimum resolvable contrast has been found to be less than 36 CT numbers at the dose of 95 mGy and the spatial resolution about 14 lp/mm. As small animal imaging results, we present high resolution 3-D images of rat organs including a femur, a heart and vessels. We expected that the developed micro-CT system can be greatly used in biomedical studies using small animals.

• Radiation Oncology Journal
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• v.36 no.3
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• pp.227-234
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• 2018

Purpose: We compared how doses delivered via two-dimensional (2D) intracavitary brachytherapy (ICBT) and three-dimensional (3D) ICBT varied anatomically. Materials and Methods: A total of 50 patients who received 30 Gy of 3D ICBT after external radiotherapy (RT) were enrolled. We compared the doses of the actual 3D and 2D ICBT plans among patients grouped according to six anatomical variations: differences in a small-bowel V_2Gy, small bowel circumference, the direction of bladder distension, bladder volume, sigmoid V_3.5Gy, and sigmoid circumference. Seven dose parameters were measured in line with the EMBRACE recommendations. Results: In terms of bladder volume, the bladder and small-bowel D_2cc values were lower in the 150-250 mL bladder volume subgroup; and the rectum, sigmoid, and bladder D_2mL values were all lower in the >250 mL subgroup, for 3D vs. 2D ICBT. In the sigmoid V_3.5Gy >2 _mL subgroup, the sigmoid and bladder D_2mL values were significantly lower for 3D than 2D ICBT. The bladder D_2mL value was also significantly lower for 3D ICBT, as reflected by the sigmoid circumference. In patients with a small bowel V_2.0Gy >10 mL or small bowel circumference >15%, most dose parameters were significantly lower for 3D than 2D ICBT. The bladder distension direction did not significantly affect the doses. Conclusion: Compared to 2D ICBT, a greater bladder volume can reduce the internal 3D ICBT organ dose without affecting the target dose.

• Kyungpook Mathematical Journal
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• v.50 no.3
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• pp.447-454
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• 2010

In this paper, we investigate the uniqueness problems of meromorphic functions that share a small function with its differential polynomials, and give a result which is related to a conjecture of R. Br$\"{u}$ck and improve the results of I. Lahiri and Q. C. Zhang.

• Proceedings of the KIPE Conference
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• 1998.10a
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• pp.642-647
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• 1998

A new small-signal model for the controlled on-time boost power factor correction (PFC) circuit is presented. The proposed small-signal model is valid up to high frequencies over lKHz. The model can be used in designing the voltage feedback compensation of PFC circuits, the control bandwidth of which is maximized with auxiliary means of removing the low-frequency ripple from the output. The accuracy of the model is confirmed by a 200W experimental hardware

• The Journal of Sustainable Design and Educational Environment Research
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• v.22 no.4
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• pp.1-8
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• 2023

The downsizing of schools is accelerating due to a rapid decline in the school-age population, and as the crisis over regional and school disappearance increases, the need for smaller schools to respond to future educational needs is increasing. Through flexible curricula and digital/artificial intelligence-based classroom teaching improvements, students' satisfaction with school life, student creativity and character development, improved academic achievement, and strengthened cooperative communication capabilities will be observed, and teachers' teaching and learning methods will change. Educational effects such as these are important, and transforming school facilities into future-oriented spaces, including school space innovation, is required to accomplish them. This study examined the future of education systems in small schools, focusing on analyzing the educational effects and awareness of the sustainability of spatial innovation, in terms of school space changes, school education correlation, and smart environment, to develop innovation projects in small schools. A desirable direction for implementation is presented.

• Proceedings of the Korea Society of Information Technology Applications Conference
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• 2002.06a
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• pp.7-9
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• 2002

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2007.05a
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• pp.146-146
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• 2007