• 수산해양기술연구
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• 제58권1호
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• pp.1-9
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• 2022

In this study, the selection action on the mesh in the net pot for whelk (Buccinum opisthoplectum) is experimentally considered, and the selectivity was compared by the SELECT model and the Nashimoto's method with the probability model according to the contact shape of the mesh and the whelk. The experiments of the mesh size selectivity was conducted for two mesh sizes: 70 mm (inner stretched size 65.4 mm) and 44 mm (inner stretched size 39.5 mm). Selectivity experiments were conducted three times in total for each mesh size used 264 whelks. In addition, Nashimoto's method analyzed the retention probability using probability model for whether the mesh passed or not based on the carapace width of the whelk. As a result of the selectivity analysis, the 50% selection carapace width for the mesh size of 70 mm was similar to 43.62 mm in the SELECT model and 42.64 mm in the Nashimoto's method. However, the 44 mm mesh with relatively small mesh size showed differences of 40.01 mm and 26.80 mm, respectively. As for the mesh size selectivity of whelk, it was found that the smaller the mesh size, the lower the selectivity. In addition, in the selectivity study on the mesh size of whelk, an evaluation method that closely considers the contact shape between the mesh and the target species is required.

• 대한한의학원전학회지
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• 제35권2호
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• pp.33-49
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• 2022

Objectives : This paper aims to investigate the role of the sweet flavor within the contexts of 'pungent and sweet becoming Yang' and 'sour and sweet becoming Yin' and the meaning of the two concepts. Methods : Related contents in databases including the Siqu Quanshu were searched with 'pungent and sweet becoming Yang' and 'sour and sweet becoming Yin', whose understanding and application were examined. Results & Conclusions : The theories of 'pungent and sweet becoming Yang' and 'sour and sweet becoming Yin' originate from Cheng Wuji's comparison of the Gancaoqianjiangtang and Shaoyaogancaotang in the 29th verse of the Shanghanlun. The two terms first appeared in the Qing period among the Wenbing school. In other medical texts, the combination with sweet flavors could be found with salty, bitter and bland flavors other than with pungent and sour. The role of the sweet flavor in 'pungent and sweet becoming Yang' and 'sour and sweet becoming Yin' is to accomplish the dispersing and converging action slowly and effectively, by supplying energy in small amounts preventing it from happening too quickly, corresponding to its Earth nature of the Five Elements which harmonizes the Yin and Yang. While 'becoming Yin' and 'becoming Yang' could be understood as tonifying Yin and Yang, it could also be understood as 'doing Yin' and 'doing Yang', The specific actions differ according to herb and mixture. The point of distinction between the aforementioned tonification and that of medicinals that have Yin and Yang tonifying properties is that due to the other flavor that is matched with the sweet flavor, Qi is given motility which allows for tonification without stagnation.

• 한국의상디자인학회지
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• 제24권4호
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• pp.1-9
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• 2022

The purpose of this research is to improve sustainable clothes care by comparing household washer's standard course and quick course. Detergency at each course was classified by laundry weight, detergent concentration, and soils. Also, fabric damage from each course was compared. Washing experiments were carried out using two types of washing machines and three types of detergents. Using the standard soiled fabrics of EMPA 108 set, detergency was compared by laundry weight, soil, and detergent concentration. Additionally, fabric damage was evaluated using the mechanical action of MA-40. The results of the research were as follows. First, a standard course, having more working time exhibited better detergency than a quick course. However, the detergency deviation under 6kg laundry weight was as low as 9.0%. Second, detergency by the type of soil was more effective in standard course than in a quick course, but hydrophilic protein soils had a small detergency deviation at 7.6%. Moreover, hydrophobic oil, complex, and particulate soils had a higher deviation at 19.7% Third, fabric damage was in proportion to operating time. Fourth, a quick course showed approximately 80% detergency regardless of the type of detergent. in the case of using 50% of the recommended allowance by the detergent manufacturer. In conclusion, reducing the operating washing time and detergent concentration is in accordance with increasing sustainability, in the case of washing with lightly soiled fabrics under 6kg of laundry weight.

• Journal of Animal Science and Technology
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• 제65권3호
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• pp.479-489
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• 2023

Livestock production depends on the utilization of nutrients, and when this is accomplished, there is accelerated momentum toward growth with a low cost-to-feed ratio. Public concern over the consumption of pork with antibiotic residues in animals fed antibiotic growth promoters (AGP) has paved the way for using other natural additives to antibiotics, such as herbs and their products, probiotics, prebiotics, etc. Numerous feed additives are trending to achieve this goal, and a classic example is vitamins and minerals. Vitamins and minerals represent a relatively small percentage of the diet, but they are critical to animal health, well-being, and performance; both play a well-defined role in metabolism, and their requirements can vary depending on the physiological stage of the animals. At the same time, the absence of these vitamins and minerals in animal feed can impair the growth and development of muscles and bones. Most commercial feeds contain vitamins and trace minerals that meet nutrient requirements recommended by National Research Council and animal feeding standards. However, the potential variability and bioavailability of vitamins and trace elements in animal feeds remain controversial because daily feed intake varies, and vitamins are degraded by transportation, storage, and processing. Accordingly, the requirement for vitamins and minerals may need to be adjusted to reflect increased production levels, yet the information presented on this topic is still limited. Therefore, this review focuses on the role and function of different sources of minerals, the mode of action, the general need for micro and macro minerals in non-ruminant diets, and how they improve animal performance.

• 한국음향학회지
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• 제28권5호
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• pp.441-446
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• 2009

본 논문에서는 오디오 정보 분석을 이용하여 골프 통영상을 자동 색인하는 알고리즘을 제안한다. 제안하는 알고리즘에서는 입력되는 골프 동영상을 비디오 신호와 오디오 신호로 분리한 후에, 연속적인 오디오 스트림을 Adaboost Cascade 분류방식을 통하여 스튜디오 환경에서의 아나운서의 음성구간, 선수이름이 TV 화면에 소개 될 때 수반되는 음악구간, 선수들의 플레이에 따라 반응하는 관중들의 박수 및 환호성 소리구간, 필드에서의 레포터의 음성구간, 바다나 바람 등의 필드환경 잡음 사운드구간 등의 5가지 구간으로 분류한다. 그리고 드라이브 샷, 아이런 샷과 퍼팅 샷 시에 발생하는 스윙 사운드는 onset 검출과 변조스펙트럼 검증 방법을 통해 검출되며, 관객의 박수 소리 구간과 결합하여 액션 및 하이라이트를 효율적으로 색인할 수 있게 한다. 제안된 알고리즘은 오디오 신호의 간단한 연산을 통해 의미를 지니고 있는 기본구조들을 검출하기 때문에 골프 동영상에서 사용자가 원하는 부분을 빠르게 브라우징하는 임베이디드 시스템에 적용가능하다.

• Structural Engineering and Mechanics
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• 제89권6호
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• pp.557-570
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• 2024

Due to interfacial ageing, chemical action and interfacial damage, the interface debonding may appear in the interfaces of composite laminates. Particularly, the laminates display a side-dependent effect at small scale. In this work, a three-dimensional (3D) and anisotropic thick nanoplate model is proposed to investigate the effects of imperfect interface and nonlocal parameter on the bending deformation, vibrational response and buckling stability of one-dimensional (1D) hexagonal quasicrystal (QC) layered nanoplates. By combining the linear spring model with the transferring matrix method, exact solutions of phonon and phason displacements, phonon and phason stresses of bending deformation, the natural frequencies of vibration and the critical buckling loads of 1D hexagonal QC layered nanoplates are derived with imperfect interfaces and nonlocal effects. Numerical examples are illustrated to demonstrate the effects of the imperfect interface parameter, aspect ratio, thickness, nonlocal parameter, and stacking sequence on the bending deformation, the vibrational response and the critical buckling load of 1D hexagonal QC layered nanoplate. The results indicate that both the interface debonding and nonlocal effect can reduce the stiffness and stability of layered nanoplates. Increasing thickness of QC coatings can enhance the stability of sandwich nanoplates with the perfect interfaces, while it can reduce first and then enhance the stability of sandwich nanoplates with the imperfect interfaces. The biaxial compression easily results in an instability of the QC layered nanoplates compared to uniaxial compression. QC material is suitable for surface layers in layered structures. The mechanical behavior of QC layered nanoplates can be optimized by imposing imperfect interfaces and controlling the stacking sequence artificially. The present solutions are helpful for the various numerical methods, thin nanoplate theories and the optimal design of QC nano-composites in engineering practice with interfacial debonding.

• Journal of Ginseng Research
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• 제44권3호
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• pp.461-474
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• 2020

Background: Ginseng effectively reduces fatigue in both animal models and clinical trials. However, the mechanism of action is not completely understood, and its molecular targets remain largely unknown. Methods: By screening for proteins that interact with the primary components of ginseng (ginsenosides) in an affinity chromatography assay, we have identified muscle-type creatine kinase (CK-MM) as a potential target in skeletal muscle tissues. Results: Biolayer interferometry analysis showed that ginsenoside metabolites, instead of parent ginsenosides, had direct interaction with recombinant human CK-MM. Subsequently, 20(S)-protopanaxadiol (PPD), which is a ginsenoside metabolite and displayed the strongest interaction with CK-MM in the study, was selected as a representative to confirm direct binding and its biological importance. Biolayer interferometry kinetics analysis and isothermal titration calorimetry assay demonstrated that PPD specifically bound to human CK-MM. Moreover, the mutation of key amino acids predicted by molecular docking decreased the affinity between PPD and CK-MM. The direct binding activated CK-MM activity in vitro and in vivo, which increased the levels of tissue phosphocreatine and strengthened the function of the creatine kinase/phosphocreatine system in skeletal muscle, thus buffering cellular ATP, delaying exercise-induced lactate accumulation, and improving exercise performance in mice. Conclusion: Our results suggest a cellular target and an initiating molecular event by which ginseng reduces fatigue. All these findings indicate PPD as a small molecular activator of CK-MM, which can help in further developing better CK-MM activators based on the dammarane-type triterpenoid structure.

• 사상체질의학회지
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• 제9권2호
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• pp.227-243
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• 1997

The experimental study used in this paper was done to examine the clinical effects of Taeumchowetang for the gastric ulcer and the function of gastrointestinal tract using rats and mice which were administered orally the water extraction from Taeumchowetang. Then, the counter-action of the water extraction on the isolated ileum and gastric fundus, the inhibitory effects of pylorus-ligated ulcer and indomethacin-induced ulcer, the associations with gastric juice secretion, total acidity, pepsin output, the transportability in the small and large intestine, were studied with administering acetylcholine chloride and barium chloride. In addition, it was investigated whether the central nervous system related to pain control and sleeping time was influenced by Taeumchowetang. The following results have been obtained; 1. As resulting from injection of acetylcholine chloride and barium chloride into the isolated ileum of rats and mice, Taeumchowetang led to have an inhibitory effect on the muscle contraction of the ileum. Then, acetylcholine chloride was measured as lower effect than barium chloride 2. For the inhibitory effect on contraction for the gastric fundus strip in rats by either acetylcholine chloride or barium chloride, the one showed low inhibitory effect, on the other hand the other showed density-dependent effect. 3. The water extraction was given on the pylorus ligated ulcer with using two different administration groups of 1,300mg/kg and 2,600mg/kg, each result was measured as 22.9% and 36.5% for an ulcerous inhibitory effect (p<0.05). 4. According to the two administration groups, the preventive effect was tabulated 18.1% and 29.3% for indomethacin-induced ulcer (p<0.05, P<0.01). 5. For associations with gastric juice secretion, total acidity, pepsin output in the administration group 2,600mg/kg, Taeumchowetang was recognized as having an inhibitory effects related to suppressive actions involving gastric juice secretion(p<0.05), and free acidity(p<0.01), but there was no significant association with total acidity and pepsin output. 6. To know the transportability in the intestine, BaSO4 solution was used. The transportability of the small intestine in the administration group 2,600mg/kg was 22.2% which was statistically significant compared with the large intestine's transportability(P<0.01). 7. In the administration group 1,300mg/kg and 2,600mg/kg, analgesic effect with against acetic acid was measured as being 16.8% and 24.4% which was shown as statistically siginificant(p<0.01). 8. No statistically significant association between Taeumchowetang and sleeping time was found in both 1,300mg/kg and 2,600mg/kg by administering phenobarbital-Na. According to the results of this study, Taeumchowetang has agreed with the effects of literature review. Further more in this study, Taeumchowetang also has preventive effects on pylorus-ligated ulcer. Hence, Teaumchowetang can be significant effect such as both anti ulcer agent and increasing gastric activity for the patients who suffer from gastric ulcer.

• 기업가정신과 벤처연구
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• 제20권4호
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• pp.3-10
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• 2018

스마트기술에 기반한 디지털 전환의 진전과 산업간 경계의 붕괴와 더불어, 고객들에게 가장 적합한 서비스를 제공하기 위해 더욱 중요해진 문제는 고객의 문제를 이해하고, 종업원의 역량을 향상시키며, 파트너들의 역량을 증진시키는 것이다. 이것이 4차 산업혁명시대 인간중심 기업가정신의 핵심이다. 인간중심 기업가정신은 비즈니스 생태계를 발전시키고 국가의 경제발전을 이루는데 핵심적인 역할을 하는 것으로 알려져 있다. 이 연구는 기업가정신이 메타구조화 행동으로 비즈니스 생태계를 구축하고, 비즈니스 생태계의 건강성과 함께 경제발전에 영향을 미친다는 가설을 검증하고 있다. 연구결과, 기업가정신은 직접적으로 비즈니스 생태계에 영향을 미치지는 않지만 사람성장과 사업개발 두 가지 측면에서 균형잡힌 기업가정신, 즉 사람중심 기업가정신은 비즈니스 생태계의 건강성 중 기회성과 함께 일인당 국민소득의 성장에 긍정적인 영향을 끼친다는 것을 발견하였다. 다시 말해, 기회성은 사람성장과 사업개발 두 가지 측면 모두에 균형잡힌 사고를 가진 기업가에 의해 활용될 수 있고 이것이 경제성장에 영향을 미친다는 것이다. 이 논문은 또한 자료 수집과 방법론에 대해 자세히 기술하고 있다.

• 미생물학회지
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• 제43권4호
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• pp.298-303
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• 2007

청국장 및 기능성분이 첨가된 청국장 추출물이 가지는 항혈전 관련 활성을 검정하였다. 흰 콩(Golycine max)과 검은 쥐눈이콩(Rhynchosia nulubilis) 청국장과 여기에 각각 녹차, 쑥이 첨가되어 제조된 청국장에 대해 in vitro에서 항산화 및 아질산염 소거 활성, 혈소판응집 억제 및 fibrin 분해활성을 측정하였고, 가장 우수한 시료에 대해 in vitro에서 혈전억제능을 시험하였다. 항산화 활성에 있어서 흰콩이나 검은콩 청국장 모두 녹차의 첨가량 증가에 따라 활성이 급격이 증가하는 경향을 나타내었으며, 쑥을 첨가한 경우에는 활성 증가율이 녹차에 비해 다소 적었다. 아질산염 소거 작용은 모든 시료에서 90% 이상 매우 높았으나 기능성분 첨가에 의한 영향은 크지 않았다. 혈소판응집 억제 활성을 조사한 결과, 녹차나 쑥을 첨가함에 따라 그 활성이 상당히 증가되었다. 특히 흰콩이나 검은콩 청국장 모두 $0.3{\sim}1.0%$의 낮은 농도에서도 녹차나 쑥의 첨가량 증가에 따라 활성 이 크게 증가하였다. 청국장 추출물의 fibrin 분해활성을 plasmin unit으로 환산한 결과, 흰콩보다는 검은콩 청국장의 혈전용해 활성이 약간 좋았으나, 기능성분 첨가에 따른 활성증가는 크지 않았으며 특히 쑥을 첨가한 경우는 저농도에서 활성이 상당히 감소하다가 농도상승에 따라 활성이 약간 회복되는 현상을 나타내었다. 시험군중 in vitro 혈전억제 작용이 가장 우수한 녹차 첨가검은콩 청국장에 대해 마우스를 이용한 in vitro 혈전유발 억제능을 조사하여, 녹차를 첨가하지 않은 것에 비해 1.5배 정도 억제능이 높음을 확인하였다. 청국장은 혈전용해뿐 아니라 혈소판응집 억제 및 항산화 기능 등에 의해서 혈전을 억제하는 것으로 나타났으며, 녹차나 쑥 등 기능 성분 첨가시 소량 첨가에도 매우 향상된 혈전억제 활성을 가진 청국장 제조가 가능함을 확인하였다. 구순 봉합수술 후에 구개부 (palatal segment) 의 면적은 계속 증가하였다. 치조골 면적과 거리 항목의 증가는 후방부에서 크게 나타났다. 이러한 결과는 PNAM치료에 의한 치조골 정형효과는 주로 전방부에서 발생하며, 치조골의 성장은 구순 봉합수술 후에 후방부에서 주로 발생한다는 것을 의미한다.물실험을 통해 증명이 되었으나 인간을 대상으로 한 역학적 연구는 아직 기대만큼 명료한 결과들을 제시해주지 못하고 있다. 그러나 IARC나 EPA모두 인체발암물질로 분류하였고 다양한 건강영향에 대한 증거들이 있는 것은 분명한 만큼 다이옥신 노출을 최소화하려는 노력을 게을리 해서는 안 될 것이다.EX>-RA투여로 인해 위내에 발생한 무위산증(achlorhydria)이 위암 발생의 위험을 높일 것이라는 기존의 가설을 뒷받침하는 결론이라고 할 수 있었다. Mies van der Rohe의 제자들이나 그로부터 영향을 받은 수많은 건축가들은 이러한 저항과 비판에 직면하게 되며 새로운 사고의 시대적 요구 앞에 고뇌하게 된다. 한국에서는 1978년 Mies van der Rohe의 제자인 김종성이 미국에서 서울로 돌아와 '서울건축컨설탄트'를 설립하며 본격적으로 Miesianism의 규범적 건축론을 설파하기 시작하였다. 이른바 시카고 국제주의학파의 건축전수라고 할 수 있는데 '서울건축컨설탄트'를 통하여 배출된 김종성의 제자들은 명쾌하고도 간결한 건축해법의 경험을 토대름대로의 정체성을 갖고자 노력하였으나 결국 다원적 가치를 요구하는 시대적 흐름 속에 혼란을 겪고 있는 것 또한 사실이다. 본 연구는 Miesianism의 기원을 밝히고 그것의 실수와 오류를 밝힘과 동시에 현대의 여러 가지 건축유형들과 비교하여 봄으로써 Post-Miesianism의 실체와 그 미래에 대하여 고찰하여 보고자 한다. 미스의 유산이라고 할 수 있는 Miesianism의 요체는 첫째, Schinkel로부터 이어받은 시대정신의 사명감,