• Journal of Ginseng Research
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• 제12권2호
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• pp.135-144
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• 1988

갑상선호르몬 분비조절물질(TSH, DB cAMP, NaF, carbachol, isoproterenol, propranolol)과 인삼성분(total saponin, diol saponin, triol saponin)의 복합처리가 갑상선의 cAMP의 양에 미치는 영향을 알아보기 위하여, 흰쥐의 갑상선을 4일 또는 7일간 배양한 후 갑상선호르몬 분비조절물질과 인삼성분을 각각 복합처리, 또는 단독처리하여 cAMP의 양을 조사하였다. 인삼성분만을 처리한 경우, total saponin은 $10^{-5}$%(w/v), diol saponin과 triol saponin은 $10^{-4}$%(w/v)의 농도에서 각각 가장 높은 증가를 나타내었다. 갑상선호르몬 분비조절물질과 복합처리한 인삼성분의 농도는 위의 값으로 하였다. 복합처리한 경우, TSH에 대해서는 증가효과를 나타냈지만 그 양상은 작았다. Total saponin은 DBcAMP와 isoproterennol에 대해서는 증가효과를, carbachol과 propranolol에 대해서는 감소효과를 나타내었고, NaF에 대해서는 영향이 크지 않았다. Diol saponin과 triol saponin은 그 양은 다르지만 isoproterenol을 복합처리한 경우를 제외하고 diol saponin은 감소효과를, triol saponin은 증가효과를 보이는 상반작용을 나타내었다. 억제효과를 가지는 propranolol에 대해서도 diol saponin과 triol saponin은 상반되는 효과를 나타내었다. 인삼성분의 정상화작용은 NaF와 carbachol의 경우에도 두드러지게 나타났다. 이상의 결과들은 인삼성분이 갑상선호르몬의 생성과 분비에 관여하는 cAMP의 생성에 촉진 또는 억제를 가진다는 것을 나타내고 있다.

• 한국인터넷방송통신학회논문지
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• 제15권6호
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• pp.311-319
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• 2015

본 논문에서는 산업공장 내의 생산 효율을 높이기 위하여 제조공정 자원을 예측하고 위험 관리를 효율적으로 이행하는 자원예측 및 위험관리를 위한 의사결정 시스템을 제안하였다. 각 공정에서 발생되는 다양한 정보들을 효율적으로 관리하는 세부 공정별 시나리오 생성이 어렵고, 동일한 공정 내에서도 다양한 제품의 생산하기 위해 제조 설비의 조건 변경이 빈번하다. 제품의 생산 주기 또한 일정하지 않아 연속되지 않은 데이터가 발생하여 소량의 데이터로 변동을 확인해야 하는 문제점이 있다. 이러한 문제점을 해결하기 위해서는 제조공정의 데이터 일원화, 공정 자원 예측, 위험 예측, 공정 현황 모니터링을 통하여 문제 발생시 즉각 조치가 가능하여야 한다. 본 논문에서는 설계도면 변경 범위, 자원 예측, 공정 완료 예정일을 회귀알고리즘을 이용하여 수식을 도출하였으며, 분류 트리 기법, 경계값 분석을 통하여 3단계로 의사결정 시스템을 제안하였다.

• 통상정보연구
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• 제17권1호
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• pp.57-85
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• 2015

최근 우리나라 중소기업의 수출기여도가 점점 약화되고 있는데 이에 대한 개선책을 수출마케팅 플랫폼 측면에서 제시하였다. 보유자원과 전문 인력이 취약한 한국 중소기업들은 수출에 있어 정부 등 지원기관의 수출지원 프로그램에 대한 의존도가 비교적 높으므로 프로그램의 운용시스템은 매우 중요하다. 본 연구는 수출지원프로그램의 운용측면에서의 개선점과 중소기업의 수출성과 창출을 위한 '수출마케팅 지원플랫폼'을 제안하였으며, 이 플랫폼을 적용하여 일선 중소기업을 1년간 지원한 사례와 성과를 소개한 연구이다. 본 플랫폼은 기업이 수출을 시작한 후 조기에 수출성과를 낼 수 있는 마케팅 방법론과 활동(activity) 그리고 프로세스에 초점을 맞추었으며, 국제마케팅 역량 강화에 도움이 되는 수출지원 프로그램들의 조합(combination)과 운영방안에 주안점을 둔 개념적 모형이다. 본 모형을 활용하면 중소기업은 저비용으로 비교적 짧은 기간 내에 수출성과를 낼 수 있다. 지원기관의 입장에서도 기존의 단조로운 수출지원 시스템에서 벗어나 제품의 특성에 따라 다양한 수출지원 프로그램을 소화할 수 있는 탄력적인 지원 플랫폼을 확보함으로서 수출지원의 효과를 배가시킬 수 있다. 본 연구 결과는 정부를 비롯한 수출지원기관들이 중소기업의 해외마케팅을 효과적으로 지원하는 '통합수출지원 플랫폼'으로 활용될 수 있을 것이다.

• 산업경영시스템학회지
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• 제40권4호
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• pp.171-182
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• 2017

Most people seek a happy life and happiness positively affects sentiment, satisfaction with life, creativity, human relationship, business productivity, and even health and life extension. However, according to a survey in 2013, subjective happiness of adolescents (including university students) was very low compared to other age groups in Korea. Therefore this paper examined the effects of job-seeking stress, appearance recognition, financial situation, trust in government, and locus of control on university students' happiness using SEM (structural equation modeling). 207 university students in Seoul, Korea have been surveyed. At first, an initial experimental SEM model among these variables has been set up and reliability analysis has been conducted. Then multiple regression analyses on job-seeking stress and happiness as well as SEM analysis have been conducted. As a result of these analyses, the SEM model has been revised two times. The final SEM model passed the goodness-of-fit test (using RMR, GFI, NFI, CFI, and IFI indices). The final SEM model showed the followings. First, Higher job-seeking stress (especially sentimental part, rather than environment or action related parts) negatively affects happiness. Second, Trust in government also affects happiness both directly and indirectly. Third, Locus of control is affected both by trust in government and financial situation. Fourth, appearance recognition heavily affects job-seeking stress. In addition, appearance importance is higher than appearance interest, meaning that students who are not very interested in appearance usually recognize the importance of appearance. Finally, happiness is affected neither financial situation nor appearance recognition. Therefore, even either they are in a poor financial situation or not happy with their appearance, they can be happy if they have firm locus of control.

• International Journal of Oral Biology
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• 제34권1호
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• pp.43-48
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• 2009

Thrombin-induced platelet microbicidal protein (tPMP) is a small cationic peptide that exerts potent in vitro microbicidal activity against a broad spectrum of human pathogens, including Staphylococcus aureus and Streptococcus rattus BHT. Earlier evidence has suggested that tPMP targets and disrupts the bacterial membrane. However, it is not yet clear whether membrane disruption itself is sufficient to kill the bacteria or whether subsequent, presumably intracellular, events are also involved in this process. In this study, we investigated the microbicidal activity of rabbit tPMP toward S. rattus BHT cells in the presence or absence of a pretreatment with antibiotics that differ in their mechanisms of action. The streptocidal effects of tPMP on control cells (no antibiotic pretreatment) were rapid and concentration-dependent. Pretreatment of S. rattus BHT cells with either penicillin or amoxicillin (inhibitors of bacterial cell wall synthesis) significantly enhanced the anti-S. rattus BHT effects of tPMP compared with the effects against the respective control cells over most tPMP concentration ranges tested. On the other hand, pretreatment of S. rattus BHT cells with tetracycline or doxycycline (30S ribosomal subunit inhibitors) significantly decreased the streptocidal effects of tPMP over a wide peptide concentration range. Furthermore, pretreatment with rifampin (an inhibitor of DNA-dependent RNA polymerase) essentially blocked the killing of S. rattus BHT by tPMP at most concentrations compared with the respective control cells. These results suggest that tPMP exerts anti-S. rattus BHT activity through mechanisms involving both the cell membrane and intracellular targets.

• 천문학회보
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• 제41권1호
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• pp.37.2-37.2
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• 2016

There exist scaling relations that link the mass of supermassive black holes with both the velocity dispersion and the mass of the central stellar cusp of their host galaxies. This implies that galaxies co-evolve with their central black holes, potentially through the feedback from actively accreting supermassive black holes (AGN). We use integral field spectroscopy data from the 8.2m Gemini-North telescope to investigate ionized gas outflows in luminous local (z<0.1) Type 2 AGN. Our sample of 6 galaxies was selected based on their [OIII] dust-corrected luminosity (>$10^{42}erg/s$) and signatures of outflows in the [OIII] line profile of their SDSS spectra. These are arguably the best candidates to explore AGN feedback in action since they are < 1% of a large local type 2 AGN SDSS sample selected based on their [OIII] kinematics. Expanding on previously reported results concerning the kinematic decomposition and size determination of these outflows, here we report their photoionization properties and energetics. We find strong evidence that connect the extreme kinematics of the ionized gas with AGN photoionization. The kinematic component related to the AGN-driven outflow is clearly separated from other kinematic components, such as gravitation- or stellar-driven motions, on the velocity and velocity dispersion diagram. Our spatially resolved kinematic analysis reveals that up to 90% of the mass and kinetic energy of the outflow is contained within the central kiloparcec of the galaxy. The total mass and kinetic energy of the outflow correlate well with the AGN bolometric luminosity, resulting in energy conversion efficiencies between 0.01% and 1%. Intriguingly, we detect ubiquitous signs of ongoing circumnuclear star formation. Their small size, the centrally contained mass and energy, and the universally detected circumnuclear star formation cast doubts on the potency of these AGN-driven outflows as agents of negative feedback.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2008년도 추계 학술발표회
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• pp.708-712
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• 2008

Piles and pile foundations have been in common use since very early times. Usually function of piles is to carry load to a depth at which adequate support is available. Another important use of piles is to furnish lateral support and nowadays it is getting highlighted due to the wind load, lateral action of earthquake, and so on. After Broms (1964), many researchers have been suggested methods for estimating lateral capacity of pile. But each method assumes different earth pressure distribution and lateral earth pressure coefficient and it gives confusion to pile designers. Lateral earth pressure, essential in lateral capacity estimation, influenced by pile's behavior under lateral load. Prasad and Chari (1999) assumed the rotation point of pile and suggested an equation of ultimate lateral load capacity. In this study, we investigate the depth of rotation point in both homogeneous soil and multi layered soil, and compare to the estimation value by previous research. To model the pile set up in the sand, we use the chamber and small scale steel pile, and rain drop method. Test results show the rotation point is formed where the Prasad and Chari's estimation value, and they also show multi layered condition affects to location of rotation point to be scattered.

• 융합보안논문지
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• 제15권7호
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• pp.39-45
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• 2015

최근 기업이 보유한 산업기밀은 영업비밀보호법, 산업기술유출방지법 등 다양한 산업보안 관련 법률에 의해 보호 받고 있다. 그러나 그러한 보호에도 불구하고 산업기밀의 침해 및 유출사고는 해마다 증가하고 있다. 한국산업기술보호협회의 조사에 따르면 산업기밀 유출 예상 피해액은 연평균 "50조 원"으로 추정되며 이는 중소기업 4,700여 개의 연 매출액과 맞먹는 금액이다. 이처럼 산업기밀 유출은 국가와 기업의 경쟁력은 물론이고 경제적으로도 심각한 피해를 초래한다. 하지만 산업기밀 유출범죄에 대한 투자와 노력은 피해규모에 비해 한 없이 부족한 수준이며 일부 대기업을 제외한 대부분의 기업들이 산업기밀 유출보안을 위한 별도의 조직, 인력, 예산이 없어 산업기밀 유출에 대한 대응체계가 부족한 것이 현실이다. 본 논문은 국내외 산업기밀 유출범죄 분석을 통하여 산업기밀 유출에 따른 피해실태를 파악하고 발생원인, 유출경로 등 다양한 분류체계를 통하여 산업기밀 유출범죄에 대한 전반적인 흐름을 파악하여 관련 연구에 대한 기초자료가 될 것으로 기대한다.

• 한국안전학회지
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• 제22권3호
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• pp.57-64
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• 2007

Recently, the corrosion of concrete structures has received great attention related with the deterioration of sea-side structures, such as new airport, bridges, and nuclear power plants. In this regards, many studies have been done on the chloride attack in concrete structures. However, those studies were confined mostly to the single deterioration due to chloride only, although actual environment is rather of combined type. The purpose of the present study is, therefore, to explore the influences of carbonation and freezing-thawing action to chloride attack in concrete structures. The test results indicate that the chloride penetration is more pronounced than the case of single chloride attack when the carbonation process is combined with the chloride attack. It is supposed that the chloride ion concentration of carbonation region is higher than the sound region because of the separation of fixed salts. Though the use of fly ash pronounces the chloride ion concentration in surface, amounts of chloride ion penetration into deep region decreases with the use of fly ash. The small reduction of relative dynamic elastic modulus induced from freezing-thawing increases the chloride ion penetration depths much. The present study allows more realistic assessment of durability for such concrete structures which are subjected to combined attacks of both chlorides and carbonation or freezing-thawing but the future studies for combined environment will assure the precise assessment.

• 대한인간공학회지
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• 제29권6호
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• pp.925-932
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• 2010

Most of the research on three-dimensional interaction field have showed different accuracy in terms of sensing, mode and method. Furthermore, implementation of interaction has been a lack of consistency in application field. Therefore, this study is to suggest research trends of three-dimensional interaction using meta-analysis. Searching relative keyword in database provided with 153 domestic papers and 188 international papers covering three-dimensional interaction. Analytical coding tables determined 18 domestic papers and 28 international papers for analysis. Frequency analysis was carried out on method of action, element, number, accuracy and then verified accuracy by effect size of the meta-analysis. As the results, the effect size of sensor-based was higher than vision-based, but the effect size was extracted to small as 0.02. The effect size of vision-based using hand motion was higher than sensor-based using hand motion. Therefore, implementation of three-dimensional sensor-based interaction and vision-based using hand motions more efficient. This study was significant to comprehensive analysis of three-dimensional motion recognition for interaction and suggest to application directions of three-dimensional interaction.