• 대한한방소아과학회지
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• 제15권1호
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• pp.77-104
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• 2001

The effects of the oriental herbal medicine Saenghyetang(SHT, 生慧湯), which consists of Rehmanniae Radix (熟地黃 九蒸: was made by 9th steam) 40g, Corni Fructus(山茱黃) 16g, Polygalae Radix(遠志) 8g, Zizyphi Spinosae Semen(酸棗仁) 2g, Biotae Semen(柏子仁 去油: oil ingredient was removed) 20g, Poria Cocos(茯笭) 12g, Ginseng Radix(人蔘) 12g, Acori Graminei Rhizoma(石菖蒲) 2g, Sinapis Semen(白芥子) 8g, on learning ability and memory were investigated. Hot water extract(HWE) and ethanol extract(EE) from SHT were used for the studies. Learning ability and memory are related to modifications of synaptic strength among neurons that interactive. Enhanced synaptic coincidence detection leads to improved learning ability and memory. If the NMDA receptor, a synaptic coincidence detector, acts as a graded switch for memory formations, enhanced signal detection by NMDA receptors should enhance learning ability and memory. It was shown that NR2B was increased in the forebrains of oriental medicine-administrated mice, leading to enhanced activation of NMDA receptors and facilitating synaptic potentiation in response to stimulation at 10-100 Hz. These HWE-SHT treated mice exhibited that superior ability in learning and memory when performing various behavioral tasks, showing that NR2B is enhanced by HWE-SHT treatment and also is critical in gating the age-dependent threshold for plasticity and memory formation. NMDA receptor-dependent modifications, which were mediated in part by HWE administration, of synaptic efficacy, therefore, represent a mechanism for associative learning ability and memory. Results suggest that oriental medical enhancement of NR2B contributes to increase intelligence and memory in mammals On the other hand, to examine the effects of EE-SHT on the learning ability and memory in experimental mice, EE-SHT was tested on passive and active avoidance responses. The EE-SHT ameliorated the memory retrieval deficit induced by ethanol in mice, but not other memory impairments. EE-SHT(10, 20mg/100 g, p.o.) did not affect the passive avoidance responses of normal mice in the step through and step down tests, the conditioned and unconditioned avoidance responses of normal mice in the shuttle box, lever press performance tests and the ambulatory activity of normal mice in a normal condition. However, EE-SHT at 20 mg/kg significantly decrease the spontaneous motor activity during the shuttle box test, and also to extend the sleeping time induced by pentobarbital in mice. These results suggest that SHT has an ameliorating effect on memory retrieval impairments and a weak tranquilizing action.

• 치위생과학회지
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• 제12권3호
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• pp.279-286
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• 2012

대상자 특성에 따른 여러 가지 비만유형과 치주질환과의 관련성을 분석하기 위하여 2010년 3월 2일부터 6월 30일까지 서울, 인천, 경기 지역에 거주하며 자원봉사센터에 봉사자로 등록된 20세 이상의 성인을 대상으로 수집한 429명의 자료를 chi-square test, Multivariable logistic regression 그리고 Statistics were analyzed linear regression analysis를 이용한 분석 결과는 다음과 같다. 1. 대상자 특성에 따른 비만유형과 치주질환의 관련성은 WHR에 의한 비만 판정 군이 정상 군에 비해 칫솔질 횟수에서 일일 2회에서는 2.22배(95% CI: 1.17-4.28), 3회에서는 3.34배(95% CI: 1.53-7.27) 높게 나타났고, 스트레스 자각수준에서 0-3점에서는 2.47배(95% CI: 1.09-5.59), 4-6점에서는 3.99배(95% CI: 1.75-9.08) 높게 나타났으며, 수면시간에서는 8시간 이상 군에서 4.20배(95% CI: 2.11-8.34) 높게 나타났다. 2. 치주질환과 관련성을 나타낸 비만유형은 WHR로 복부비만 군은 정상 군에 비해 치주질환에 이환될 가능성이 2.56배(95% CI: 1.587-4.138) 높았으며, BMI와 PBF에서는 유의한 관련성이 확인되지 않았다. WHR은 비만진단 지표 중 치주질환에 가장 영향력 있는 지표로 비만으로 판정 받은 경우 치주질환을 함께 가지고 있을 위험이 높아지므로 이들에 대한 정기적인 치주관리의 필요성은 더욱 강조되어야 할 것으로 사료되었다.

• 전자공학회논문지
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• 제53권1호
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• pp.9-21
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• 2016

IP 네트워크에서 에너지 소모를 줄이기 위해 다양한 방법이 연구 되어 왔다. 본 논문에서는 다양한 에너지 프로파일을 갖는 IP 네트워크에서 2단계 라우팅 방식을 제시하고, 그 특성을 분석한다. 단계1의 라우팅 방식에서는 에너지 절약을 위해 기존 코스트 외에 에너지 코스트를 고려한 OSPF 라우팅이고, 단계2에서는 가능한 많은 코아 노드를 sleep 상태로 만든 후, sleep 노드로 영향을 받는 경로만 재 라우팅 하는 방식을 적용한다. 이때 단계2에서 에너지 절약 특성과 네트워크 레벨의 QoS 보장을 위한 방법으로, 재 라우팅 시 허용 가능한 증가 홉 수와 링크 및 노드의 이용률을 제한함으로써 에너지 효율 개선 및 네트워크 레벨의 지연 특성을 동시에 만족시킬 수 있다는 것을 확인한다. 또 sleep 모드로 둘 코아 노드를 선정하는 방법에 따라 에너지 절약 효율 및 지연 특성이 다르며, MP (minimum_path)에 기초하여 sleep 상태로 만들 코아 노드를 선정하는 방식이 우수함을 나타낸다.

• 대한치과기공학회지
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• 제37권3호
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• pp.157-167
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• 2015

Purpose: This study studied and investigated the oral health behavior of students in the Department of Dental Technology at D College at D City. Methods: A self-administrated survey was conducted by students currently enrolled at the Department of Dental Laboratory Technology at D College (June 4, 2015 ~ June 12, 2015), and 320 copies that were available for statistical processing were statistically analyzed by using the SPSS 19.0 Program. Results: Among the survey respondents, 91.6% had experience of dental treatment. The highest response regarding the frequency of tooth brushing appeared to be 'twice' with 44.7%. The responses regarding the time of tooth brushing appeared to be highest for 'before sleeping' with 65.3%, which was followed by 'after breakfast' with 60.6%. To the question asking which areas are brushed during tooth brushing, the response of 'teeth, gum, and tongue' appeared to be highest with 44.4%. Among the respondents, 64.7% experienced scaling, however, the experience rate for scaling appeared to increase in proportion with the increase of class year (p< .001). Regarding the subjective feel for the importance of oral health and necessity of tooth brushing, the scores appeared to be both 4.56. However, the score appeared to be 3.27 regarding one's subjective perception of one's own oral health condition. Regarding one's subjective oral health knowledge level depending on gender, female students showed a meaningfully lower rate (3.12 points) compared to male students (3.29 points) (p< .05), and depending on class, the knowledge level appeared to be meaningfully higher along with the increase in class year (p< .001). The experience of receiving oral health education appeared to be 78.4%, and 88.8% of the respondents responded that there is need for oral health education, however, the intent to participate in an oral health education program appeared to be 56.6%. Conclusion: As a result of the study, it could be concluded that oral health management behaviors and awareness of the students at the Department of Dental Technology at D University to prevent oral diseases were rather poor.

• 사물인터넷융복합논문지
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• 제6권2호
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• pp.57-64
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• 2020

본 연구는 간호대학생의 스마트폰 중독, 수면상태, 학업성취가 정신건강에 미치는 영향을 파악하기 위해 시도되었다. 연구대상자는 간호대학에 재학 중인 2, 3학년 학생 185명으로, 자료수집기간은 2019년 5월 13일부터 2019년 6월 3일까지이다. 수집된 자료는 IBM SPSS/WIN 24.0프로그램을 이용하여 기술통계, Independent t-test, one-way ANOVA, Pearson correlation, 위계적 다중회귀분석으로 분석하였다. 간호대학생의 스마트폰 중독점수는 36.99점(60점 만점)이었으며, 스마트폰 중독이 심할수록 수면상태(r=.19, p=.009)와 정신건강(r=.34, p<.001)이 좋지 않은 것으로 나타났다. 간호대학생의 정신건강에 영향을 주는 변수로는 스마트폰 중독, 수면시간, 학년, 수면상태였으며, 스마트폰 중독(β=.27)이 가장 큰 영향력을 주는 것으로 나타났다. 영향요인에 의한 설명력은 20.4%였다. 따라서 간호대학생의 정신건강을 위하여 스마트폰 중독을 낮출 수 있는 다양한 프로그램의 적용과 수면에 대한 관리가 이루어져야 한다.

• 부모자녀건강학회지
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• 제2권
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• pp.83-110
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• 1999

The purpose of this study was to identify the sleep/activity patterns of neonates and to provide a baseline data for the development effective mother-infant relationship. Subjects of this study were 36 newborns aged 1-21 days and stayed in Postpartum Care Center in Taejon during the period of October 28th, 1999 to February 10th, 2000. The data were collected using NCASA developed by Barnard et al. and were analyzed with SPSS 7.5 for window program. The results of this study were as follows: 1. An average day sleep of neonates was 8.0 hours, night sleep was 3.6 hours, and total sleep was 11.6 hours. A longest period of day sleep was 3.8 hours and a longest period of night sleep was 3.4 hours. The regularity of day sleep was 22.1%, night sleep was 23.3%, and total was 22.1%. 2. The frequency of daytime feeding was 6.9, nighttime fee ding was 3.4, resulting in total of 10.3. The regularity of feeding was 37.4%, and the frequency of night awakening was 2.4. 3. Associations among variables related to neonate's sleep/activity records were as follows : - The regularity of total sleep was positively correlated with the frequencies of day sleep(r=.57, P=.00), night sleep (r=.40, P=.01), and total sleep(r=.65, P=.00). - The frequency of total feeding was negatively correlated with the frequencies of day sleep(r=-.29, P=.04), night sleep(r=-.39, P=.02), and total sleep(r=-.42, P=.00), as well as longest day sleep(r=-.50, P=.00). - The regularity of feeding was negatively correlated with the frequency of night sleep(r=-.35, P=.02), longest period of day sleep(r=-.32, P=.04), and longest period of night sleep(r=-.30. P=.04), whereas positively correlated with frequencies of daytime feeding (r=.29, P=.02) and nighttime feeding (r=.32, P=.05). - The frequency of night awakening was negatively correlated with amount of night sleep(r=-.39, P=.02) and frequency of daytime feeding(r=-.42, P=.01) while positively correlated with frequencies of nighttime feeding(r=.68, P=.00) and total feeding(r=.50, P=.00). 4. Although there was no statistical significant difference between sleep pattern and infant's age, following tendency was noted: - As baby gets older, total amount of sleep and longest period of day sleep decreased while longest period of night sleep increased. - As baby gets older, the regularity of day sleep decreased while the regularity of night sleep and total sleep slightly increased. - The frequencies of daytime and total feedings increased while the frequency of nighttime feeding decreased. In conclusion, the author found that the neonates of this study showed less amount of sleep, more night awakening, and more night time feedings than NCAST sample. There was a certain sleep/activity pattern existed: If babies were fed more frequently, daytime or nighttime sleeping hours became shorter, and if babies had longer daytime sleep, frequent nighttime awakenings were noted. This pattern illustrated the significant influence of feeding and sleep periods on each other. Awakening in the night is natural and normal patterns in the newborn period. The result of this study will provide information to parents about what to expect their infants.

• 생명과학회지
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• 제16권7호
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• pp.1214-1218
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• 2006

페놀성 화합물들의 병용투여가 rat의 진정효과에 미치는 영향을 조사하였다. 천마성분으로서 positive GABAergic neuromodulation을 보이는 4-hydroxy-3-methoxybenzaldehyde와 강력한 항산화물질인 2,3-dihydroxlrbenzaldehyde를 동량 투여한 결과, pentyleneterazole에 의해 유발된 사망률이 유의하게 감소되었으며 pentobarbital에 의해 유도된 수면시간은 유의하게 연장되었으나 항불안효과와 근육이완효과는 나타나지 않았다. 이러한 결과로 보아 항경련효과를 가진 화합물과 항산화 효과를 가진 화합물을 병용투여 함으로서 경련이나 불면 등의 신경증상을 효과적으로 억제할 수 있을 것으로 사료된다.

• 지역사회간호학회지
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• 제12권1호
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• pp.187-201
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• 2001

This study was conducted to investigate the health status and health promoting behavior of older adults in rural area. The design of research was descriptive study. 883 older adults over sixty years living in the rural area of Pusan city were surveyed from July 9. 1999 to July 20. 1999 through direct interview using a questionnaire and physical examination. The collected data were analyzed for percentage. mean. Chi square-test. ANOVA using the SPSS computerized program. The main results were as follows: 1. 43.4% of subjects lived alone or with only partner. 2. 37.13% of subjects had perceived own health condition as bad. 3. Major 'chronic diseases that the subjects were suffered were diabetes(25.94%) and hypertension(9.11%). 4. The mean score of perceived depression was 17.71 of 44. 5. 87.98% of subjects replied that they had good relationship with their family and friends. 6. 8.57% of subjects were identified as over weight. while 10.85% were low weight. 7. 29.93% of subjects replied that they were smoking. By the group. the rate of smoking of man was significantly higher than women. and lower age group than higher age group, and higher education group than lower education group. 8. 70.38% of subjects didn't practice exercise. By the group, the rate of exercise of woman was significantly lower than man, and higher age group than lower age group, and lower education group than higher education group. 9. 12.33% of subjects replied for the frequency of drinking as more three -times a week. By the groups. man showed significantly more frequency than woman. the lower age group than higher age group, the lower education group than the higher education group. 11. The mean score of nutrition state was 3.73 which means moderate risk state. 12. The 57.53% of subjects replied, their sleeping time as below 7 hours. 13. The 15.75% of subjects had experience a periodical inspection. In conclusion, older adults in rural area were identified having various health risk factor, Looking at the results. It is necessary to develope health promotion program which enhances older adults to practice health promoting behavior and to manage their chronic disease.

• 한국산학기술학회논문지
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• 제17권5호
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• pp.506-515
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• 2016

본 연구는 노인들의 우울수준 및 그와 관련된 요인을 파악하고자 도시지역 노인 386명을 대상으로 2015년 7월부터 8월까지의 기간 동안에 구조화된 무기명식 면접조사용 설문지를 사용하여 면접조사를 실시하였다. 연구결과, 조사 대상자의 우울수준 평균 점수는 연령이 높을수록, 학력이 낮을수록, 혼자 사는 군에서, 월수입이 낮을수록, 생활비를 정부로부터 보조 받는다는 군에서, 만성질환이 있다는 군에서, 주관적 건강상태가 좋지 않다는 군에서, 운동을 규칙적으로 하지 않는다는 군에서, 주관적 수면의 질이 좋지 않다는 군에서, 외출 빈도가 낮을수록, 식사를 규칙적으로 하지 않는다는 군에서, ADL, IADL의 도움이 필요하다는 군에서, 자아존중감 및 사회적 지지도가 낮은 군에서 유의하게 높았다. 조사 대상 노인들의 우울수준(CES-D)은 ADL 및 IADL과 양의 상관관계를 보인 반면, 자아존중감 및 사회적 지지와는 음의 상관관계를 보였다. 우울수준을 종속변수로 한 다중회귀분석 결과, 우울수준에 영향을 미치는 요인으로는 학력, 월수입, 주관적 건강상태, ADL, 자아존중감 및 사회적 지지 순이었으며 변인들에 의한 설명력은 54.1%이었다. 따라서 이 같은 요인들을 고려한 노인들의 우울수준을 낮추기 위한 프로그램의 개발과 활용방안이 모색되어야 할 것으로 생각된다.

• 한국산학기술학회논문지
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• 제16권6호
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• pp.3889-3901
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• 2015

70세 이상 후기노인의 사회적자본이 건강관련 삶의 질에 미치는 영향을 알아보고자 M시의 70세 이상 후기노인 258명에 대해 1차는 2013년 10월 15일부터 11월 15일까지, 2차는 2014년 12월 1일부터 12월 30일까지 설문조사를 실시하였다. 수집된 자료는 SPSS 18.0과 AMOS 21.0 프로그램의 구조방정식 모형을 활용하여 분석하였으며, 매개효과의 통계적 유의성을 분석하기 위해 소벨검증(sobel-test)을 실시하였다. 사회적자본이 건강관련 삶의 질에 미치는 요인은 성별, 교육수준, 동거여부, 운동 여부, 수면시간, 도움요청가족수, 도움요청친척수, 일반신뢰가 영향을 미치는 것으로 나타났다(p<0.05). 연구 모형을 검증한 결과 사회적자본은 건강관련특성에 직접적 영향을 미치고, 건강관련특성은 삶의 질에 직접적 영향을 미치는 것으로 나타났다. 사회적자본은 건강관련 삶의 질에 간접접인 영향을 미치는 것으로 나타났다. 연구 결과를 통해 후기 노인들의 사회적자본이 건강관련 삶의 질에 영향을 미치는 요인들 중의 하나로 인식될 수 있으며 건강관련 삶의 질을 향상시키고, 사회적자본 수준을 증대시키기 위한 정책마련을 제안한다.