• Journal of Physiology & Pathology in Korean Medicine
• /
• v.34 no.2
• /
• pp.88-96
• /
• 2020

Stauntonia hexaphylla (SH) and Vaccinium bracteatum (VB) are herbal extracts widely used in food and traditional herbal medicine, and have the ability to perform a wide range of biological activities. We aimed to investigate the effects of the SH and VB combination (SHVB) on mice models of chronic restraint stress (CRS) and pentobarbital-induced sleeping behaviors to elucidate its possible mechanisms of action. CRS-exposed mice treated with SHVB showed significantly decreased immobility time, increased swimming and climbing times in the forced swim test (FST), and increased locomotor activity in the open field test (OFT). SHVB decreased serum CORT levels, but enhanced brain monoamine neurotransmitters. SHVB significantly decreased the sleep latency and increased total sleep duration in pentobarbital-induced sleeping behavior in mice. SHVB showed inhibitory effect on 5-HT_2A receptor-mediated ERK1/2 phosphorylation. These results suggest that SHVB has antidepressant and hypnotic effects by regulating the 5-HT_2A receptor.

• Journal of Korean Academy of Nursing
• /
• v.29 no.3
• /
• pp.507-517
• /
• 1999

The purpose of this study is to understand home care needs for parturient women and neonates up to the postpartum period. Methodology : The design of this study is a cross-sectional survey study. The subjects of this study are 88 postpartum mothers who delivered a first baby during the period from December 1996 to July 1997. Data collection was done with a structured questionnaire by mailing. Data were collected at the point of six months after delivery. A structured questionnaire composed of items related to home care needs. Data analysis was done with descriptive statistics. The study results are as follows : .The highest need was personal hygiene(93.2%) for the parturient women, and the peak period was the two week period after delivery. .The most frequent maternal needs regarding neonates were cord care (72.4%) during the first week, elimination(67.9%) during the first two weeks, baby crying(88.3%) and sleeping pattern(71.5%) at one month after delivery, and baby temperament(30.4%) at sixth months after delivery. .The mothers requested home care methods such as written material for self health care (35%) and counseling(34%) and direct home visits (5%) for neonate care. - Conclusion : The most important period for home health care needs was one week after delivery, and the health care needs for neonate temperament, behavior and sleeping pattern rose rapidly at the period of 6 months after delivery. Therefore it could be concluded that the postpartum home care should be done by those, written material should be enhanced for parturient women care, and counseling enhanced for neonate care.

• Korean Journal of Occupational Health Nursing
• /
• v.24 no.3
• /
• pp.245-257
• /
• 2015

Purpose: This study was performed to investigate the present condition of drug abuse and its association with depression, self-rated health and health behaviors by job status in Korean adults. Methods: Data were derived from the study on four addiction problem and suicide in 2014. Multiple logistic regression was used to analyze patterns of drug abuse according to depression, self-rated health and health behaviors. Results: The prevalence of drug abuse during the past year was 17.1% of the 4,018 subjects. About 3.3 times risk for drug abuse was found among individuals who had high depression scores. The risk of drug abuse was higher among those who were smoking (OR:1.46, 95% CI:1.17~1.83), drinking more frequently (OR:1.30, 95% CI:1.07~1.58), sleeping insufficiently (OR:1.31, 95% CI:1.03~1.67), eating irregularly (OR:1.45, 95% CI:1.19~1.76). Drug abuse problem was detected more seriously among employed than unemployed adults. Conclusion: Health-related behaviors, such as smoking, drinking, sleeping, eating should be considered simultaneously when designing strategies to deal with drug abuse problem, and it is important to understand the interaction between drug abuse and mental health. Furthermore, workplace based intervention can be effective in solving drug abuse problem.

• Biomolecules & Therapeutics
• /
• v.7 no.3
• /
• pp.271-277
• /
• 1999

Safety evaluation of LB71350, a new HIV-1 protease inhibitor, was performed in mice, rats and dogs. For the general behavior of mice, LB71350 at an oral dose of 200 mg/kg did not show any significant effects on muscle tone and locomotor activity. In terms of central nervous system, at oral doses of 200 mg/kg and 1000 mg/kg, LB71350 inhibited acetic acid-induced pain response approximately 41% and 83% of control. respectively. At oral doses of 200 mg/kg and 500 mg/kg, it reduced the rectal body temperature in rats. Pentylenetetrazole-induced seizure in mice was slightly potentiated by oral administration of LB71350 at doses ranging from 200 mg/kg to 1000 mg/Ag. Single or five day treatment of LB71350 doubled the hexobarbital- induced sleeping time in mice at oral doses ranging from 50 mg/kg to 500 mg/kg. It did not cause any effects on gastric secretion and acidity in rat at oral doses of 200 mg/kg and 1000 mg/kg and also it did not change intestinal motility in mice up to 1000 mg/kg. Blood coagulation indices such as prothrombin time (PT), activated partial thromboplastin time (aPTT), and thrombin time (TT) in rats were not affected by the treatment of LB71350 up to 500 mg/kg. LB71350 caused no significant effects on the cardiac output, stroke volume, heart rate, and mean blood pressure when infused intravenously to the anesthetized rats and dogs. Taken together, LB71350 at high oral doses caused significant pharmacological effects on the central nervous system and the hexobarbital-induced sleeping time.

• Journal of Korean Academy of Nursing
• /
• v.49 no.2
• /
• pp.137-148
• /
• 2019

Purpose: This study aimed to investigate the effects of a reinforcement program for behavioral skills in postpartum care for couples with their first baby. Methods: The study used a non-equivalent control group and pretest-posttest design. It was conducted from January 14 to April 10, 2016 at a postpartum care center in D city. It analyzed 43 couples (22 in the experimental group and 21 in the control group.) For data analysis, descriptive statistics, test of homogeneity in pretest, independent t-tests, and repeated measures ANOVA were used. Results: For maternal fulfillment of postpartum care and postpartum fatigue, there was no significant difference in the interaction between group and time. In terms of parent-newborns attachment, the interaction between group and time showed a significant difference for mothers (F=13.63, p=.001) and fathers (F=6.51, p=.001). In marital intimacy, the interaction between group and time showed a significant difference for mothers (F=14.40, p<.001) and fathers (F=9.46, p=.004). In parenting stress, the interaction between group and time showed a significant difference for mothers (F=31.8, p<.001) and fathers (F=11.69, p=.001). A significant difference was found for the mothers' postpartum sleeping hours (F=0.14 p=.004). Conclusion: This program for behavioral skills in postpartum care, which is based on the information-motivation-behavioral skills model, improves postpartum care, parent-newborn attachment, marital intimacy, parenting stress, and maternal postpartum sleeping, by reinforcing behavioral skills required for postpartum care.

• Journal of Korean Academy of Nursing
• /
• v.33 no.2
• /
• pp.293-300
• /
• 2003

Purpose: The purpose of this study was to describe health problems and psychosocial adaptation in children with cancer and to determine the relationship between these two variables. Method: The data were collected from parents of 61 children with cancer, aged 4-11 years at one university hospital in Seoul. The instruments for this study were the Korea Child Behavior Check List (KCBCL) and a physical symptom checklist developed by the researchers. Result: The major health problems were coughing, sleeping disturbances, fatigue and weakness. The total behavior problem score for children in the cancer group was higher than the score for those in the norm group. The scores on the scales for withdrawal, somatic complaints, social immaturity, and internalizing problems were higher in the children with cancer compared to normative findings. Scores on social and school competence in the cancer group were lower than the norms for healthy children. The relationship between health problems and psychosocial adaptation was significant in the subscales of withdrawal, anxiety/depression, internalizing problems and social involvement in the off therapy group. Conclusions: This study shows the various areas that need further study in caring for children with cancer.

• Journal of the Korean Society of School Health
• /
• v.21 no.2
• /
• pp.61-73
• /
• 2008

Purpose: Several health behavior factors affect the incidence of type 2 diabetes. Especially, obesity, which causes insulin resistance, is the most important determinant of diabetes. Therefore, we expect the risk factors associated with insulin resistance and type 2 diabetes are affected by obesity and, additionally, the related factors with diabetes caused by obesity can be controlled. Methods: This study used data collected from the 2001 Korea National Health and Nutrition Examination Survey (KNHANES). A stratified multistage probability sampling method was applied and the final sample included 5,500 subjects over 30 years old who had completed necessary health examinations and health behaviors survey. Results: The risk factors associated with type 2 diabetes are affected by obesity. According to logistic regression model stratified by body mass index (BMI) and sex, abdominal obesity and age were the significant risk factors of diabetes regardless of sex and BMI. However, drinking, smoking, total energy consumption, and protein consumption were risk factors for women with normal BMI, while carbohydrate consumption was a risk factor for man with normal BMI. Sleeping hours affected diabetes for women with obesity and fiber consumption was a risk factor for both women and men with obesity. In addition, statistically the family history of diabetes was a significant risk factor only in the group with normal weight, not in the group with obesity. Conclusion: The study results will provide information for implementing a regional initiative of type 2 diabetes prevention by BMI.

• Journal of KIISE:Computing Practices and Letters
• /
• v.16 no.4
• /
• pp.477-481
• /
• 2010

In this paper, we try to classify behavior patterns of a person around a bed based on a wireless sensor network system. We define five behavioral patterns and three states of a person around a bed which is described by a state machine. We collected data sensed by motion detection and vibration sensors installed around a bed from which a feature vector was extracted. Based on feature vector corresponding to behavioral patterns and the state machine, we established a model for behavioral patterns. To validate the model, experiments on subjects were performed and the model was fixed. These experimental results revealed that behavior patterns of a person around a bed can be classified well.

• Korean Journal of Health Education and Promotion
• /
• v.30 no.2
• /
• pp.1-10
• /
• 2013

Objectives: The objective of this study was to assess the relationship between internet addiction and health behaviors & mental health among Korean adolescents. Methods: Data from the 2010 Korean Youth Risk Behavior Web-based Survey was analyzed. Using the Korean Internet Addiction Proneness Scale for Youth-Short Form: Self Report developed by the Korean National Information Society Agency in 2008, subjects were classified into 3 groups for internet addiction including general user, potential-risk group, and high-risk group. The health behaviors and mental health were compared among the groups for internet addiction by gender. Results: There was significantly higher prevalence of internet addiction including potential-risk group and high-risk group in boys(14.1%) than in girls(8.8%). There were significant odds ratios of perceived stress, perceived depression, perceived health and happiness, and satisfaction of sleeping in both genders at potential-risk group and high-risk group compared to general user for the internet addiction. The odds ratios of smoking at high risk group, alcohol drinking at potential risk group, eating breakfast at high risk group, and moderate physical activity at both risk groups among boys were significant. Among girls at both risk group, the odds ratios of smoking, alcohol drinking, and eating breakfast were significant. Conclusions: This study reveals a significant association among internet addiction, and health behaviors, and mental health in Korean adolescents.

• Journal of Korean Dental Hygiene Science
• /
• v.4 no.1
• /
• pp.79-87
• /
• 2021

Background: The purpose of the present study was to confirm the degree of physical activity and oral health behaviors of adolescents, and to investigate the relationship between them. Methods: The present study utilized data from the 15th (2019) Korea Youth Risk Behavior Web-Based Survey data, which included a total of 57,303 adolescents for analysis. Statistical analysis was performed using PASW Statistics 21.0. The significance level for significance was set at 0.05. Results: The rate of toothbrushing before sleeping was 1.152 times higher in the group that performed muscle strengthening exercises more than 3 times a week than in the group that did not (p < 0.001). The rate of use of oral hygiene products was 1.246 times higher in the group that performed physical activity for 60 min or more every day than in the group that did not, and 1.207 times higher in the group that performed muscle strength exercise at least 3 times a week than in the group that did not (p < 0.001). Conclusions: Adolescents who engaged in physical activities had a high rate of practice for some oral health behaviors. These results suggested that the group with positive health behaviors has a higher rate of oral health behavior practice, showing that health behaviors are highly interrelated.