Objectives: The analysis of heart rate variability (HRV) is a useful non-invasive tool to investigate the autonomic nerve function. Previous studies on the relationship between HRV and depression have been reported controversial results. Similarly, the correlation between the serum lipids and depression is debatable. The purpose of this study is to examine the relationship between heart rate variability, lipid profile and depression. Methods: A total of 42 patients with major depressive disorder (MDD) and 32 age and sex-matched normal subjects who had no previous history of major medical and mental illnesses were recruited for this study. A structured-interview was used to assess the general characteristics and psychiatric illness. HRV measures were assessed by time-domain and frequency-domain analyses. Psychological symptoms were measured using the Hamilton rating scale for anxiety (HAM-A), Hamilton rating scale for depression (HAM-D). In addition, the evaluation for lipid profile was performed by blood test. Results: In serum lipid profile test, MDD group showed higher cholesterol ($197.68{\pm}42.94$ mg/dL vs. $176.85{\pm}34.68$ mg/dL, p=0.044), TG ($139.45{\pm}92.54$ mg/dL vs. $91.4{\pm}65.68$ mg/dL, p=0.018), LDL ($130.03{\pm}33.18$ vs. $106.62{\pm}27.08$, p=0.004) level than normal control group. In HRV time domain analyses, the standard deviation of the NN interval (SDNN) was decreased in MDD group than normal control group, but was not significant ($32.82{\pm}14.33$ ms vs. $40.36{\pm}21.40$ms, p=0.078). ApEn (Approximate Entrophy) was significantly increased in MDD group than normal control group ($1.13{\pm}0.11$ vs. $0.91{\pm}0.18$, p<0.001). ApEn was correlated with LDL level (r=0.277, p=0.028), HAM-D scores (r=0.534, p<0.001) and HAM-A scores (r=0.470, p<0.001). Conclusions: MDD patients showed increased ApEn, one of the HRV measurement. And this ApEn was correlated with LDL, HAM-D and HAM-A scores. In this study, the analysis of ApEn would be a useful test of MDD.
Objectives: Chronic pain is one of the most common experiences of humans and a typical psychophysiological disorder. The aim of this study was to measure the psychophysiological responses in chronic pain patients using a biofeedback system, and to compare them with the results from normal healthy subjects. Methods: Forty two patients with chronic pain (17 males and 25 females, average age $44.67{\pm}11.10$ years) and 42 normal healthy controls (17 males and 25 females, average age $45.17{\pm}10.46$ years) participated in this study. Electromyography (EMG), skin conductance (SC), and skin temperature (ST) were recorded using biofeedback system during the 3 phases (baseline, stress, and recovery) of stress reactivity test, and average values of them were calculated. Difference of values between two groups in each corresponding phase was analyzed with independent t-test, and change of values across phases of stress reactivity test was analyzed with paired t-test (all two-tailed, p<0.05). Results: Compared to normal controls, chronic pain patients had higher value of EMG (baseline: $8.10{\pm}5.97{\mu}V$ vs $4.72{\pm}1.52{\mu}V$, t=-3.56, p<0.01; stress: $11.25{\pm}6.89{\mu}V$ vs $8.49{\pm}4.78{\mu}V$, t=-2.13, p<0.05; recovery: $7.12{\pm}3.77{\mu}V$ vs $4.78{\pm}1.59{\mu}V$, t=-3.70, p<0.01) and SC (baseline: $1.06{\pm}1.0{\mu}S$ vs $0.42{\pm}0.29{\mu}S$, t=-4.0. p<0.01; stress: $1.87{\pm}2.05{\mu}S$ vs $1.03{\pm}0.86{\mu}S$, t=-2.47, p<0.05; recovery: $1.74{\pm}1.77{\mu}S$ vs $0.64{\pm}0.59{\mu}S$, t=-3.8, p<0.01) in all the 3 phases. But, skin temperature comparison did not reveal significant differences in all the 3 phases between two groups. Conclusion: Psychophysiological responses of chronic pain patients in stress reactivity test were different from those of normal healthy controls. These results suggest that sympathetic nervous system is more activated in chronic pain patients.
Objectives: Several evidence has been suggested that the circadian gene variants contribute to the pathogenesis of seasonal affective disorder. In this study, we aimed to investigate the polymorphism in RORA (Retinoid-related orphan receptor A) gene in relation to seasonal variations among healthy young adults in Seoul, Korea. Methods: A total of 507 young healthy adult subjects were recruited by advertisement. Seasonal variations were assessed by the Seasonality Pattern Assessment Questionnaire (SPAQ). Single-nucleotide polymorphism in the RORA rs11071547 gene was genotyped by PCR in 507 individuals. Considering summer type as confounding factor, we conducted analysis 478 subjects except 29 subjects of summer type. The Chi-square test was conducted to compare differences between groups of seasonals and non-seasonals. Association between genotypes and Global Seasonality Score (GSS) were tested using ANCOVA (Analysis of covariance). Results: In this sample, the prevalence of SAD was 12.1% (winter type 9.3%, summer type 2.8%). There is no significant difference in genotyping distribution of RORA rs11071547 between groups of seasonals and non-seasonals. Global seasonality score (GSS) and scores of all subscales except body weight and appetite were not significantly different between the group with C allele homozygote and the group with T allele homozygote and heterozygote (p-value 0.138). Scores of body weight and appetite were significantly higher in group with C allele homozygotes. Conclusion: These results suggest that RORA gene polymorphism play a role in seasonal variations in appetite and body weight and is associated with susceptibility to seasonal affective disorder in some degree in the population studied.
With the rapid advance of the semiconductor and Information and communication technologies, remote environment monitoring technology, which can detect and analyze surrounding environmental conditions with various types of sensors and wireless communication technologies, is also drawing attention. However, since the conventional remote environmental monitoring systems require external power supplies, it causes time and space limitations on comfortable usage. In this study, we proposed the concept of the self-powered remote environmental monitoring system by supplying the power with the levitation-electromagnetic generator (L-EMG), which is rationally designed to effectively harvest biomechanical energy in consideration of the mechanical characteristics of biomechanical energy. In this regard, the proposed L-EMG is designed to effectively respond to the external vibration with the movable center magnet considering the mechanical characteristics of the biomechanical energy, such as relatively low-frequency and high amplitude of vibration. Hence the L-EMG based on the fragile force equilibrium can generate high-quality electrical energy to supply power. Additionally, the environmental detective sensor and wireless transmission module are composed of the micro control unit (MCU) to minimize the required power for electronic device operation by applying the sleep mode, resulting in the extension of operation time. Finally, in order to maximize user convenience, a mobile phone application was built to enable easy monitoring of the surrounding environment. Thus, the proposed concept not only verifies the possibility of establishing the self-powered remote environmental monitoring system using biomechanical energy but further suggests a design guideline.
To investigate the relationship between dietary attitude and healthy status of office workers in Seoul was to be researched for 389 subjects (male: 224 and female: 165). As a result showed 69.4% of them moderately healthy state and 55.0% had a great interest in health. About 41.6% of the respondents was nonsmoker and 74.8% of them drunk alcohol once or twice a week. Only 28.0% of them responded to have breakfast three to four times a week. About 71.0% responded to skip breakfast'. The main reasons for it were 'the lack of time'(46.5%) and 'habitually'(22.6%). The usually preferred taste of food was showed to be 'hot' for 40.3%, the highest percentage. An attempt of supplemental food was 66.0%. The reason for it was shown to be 'for relaxation'(51.7%), followed by 'for prevention and treatment of diseases (23.1%). On dietary habit showed the groups of married and professional people won the hish scores on it. And the groups of those doing exercise once or twice a week, those having a sufficient sleep and those kept in a good food habit showed the high scores on it. The older age group showed the good dietary attitude regardless of occupation.
Purpose : The purpose of this study was to elucidate the effects of hospice care on pain management of the terminal cancer patients. Method : The subjects of the study were 37 terminal cancer patients hospitalized in the general hospital in JeonJu with the hospice care nit. The data were collected using the questionaire with interviews from July to Nov. in 2000. The severity and interference of pain were examined with the self reported survey based on the Korean version of Brief Pain Inventory (BPI-K). The data were analyzed with the mean, SDs, paired t-test. The hospice care to provide for three weeks. Results : 1) The mean scores of the worst pain for the last 24-hours measured with the pain severity of BPI-K were pre-intervention (6.35) and post (4.76). The pain interference of BPI-K in pre-intervention was enjoy (8.22), work (7.46), walk (7.08) and activity (7.08), while post was of enjoy (6.62), work (6.43), walk (6.11) and activity (5.78), respectively. 2) In pain severity, significant difference was found between the pre-intervention and post in all of followings. - worst pain for last 24 hours (t=4.085, P=.000) - least pain for last 24 hours (t=4.020, P=.000) - average pain for last 24 hours (t=4.254, P=.000) - pain right now (t=4.017, P=.000) 3) In pain interference, significant difference was found between the pre- intervention and the post in all of followings. - activity (t=3.137, P=.003) - mood (t=6.713, P=.000) - walk (t=2.027, P=.050) - work (t=2.132, P=.040) - relate (t=4.143, P=.000) - sleep (t=4.071, P=.000) - enjoy (t=3.881, P=.000) Conclusion : The terminal cancer patients who were offered hospice care had significantly lower hospice care pain and pain interference than those without hospice care. According to these results, hospice care can be regarded as an effective modality in relief of pain in the terminal ill-patients.
This study is executed to investigate convergent factors related to depression among some college women of health affiliated educations. It surveyed 419 college women in Honam area during the period from March 9th to April 30th, 2015. The structured self-administered questionary was delivered and they were collected without respondents' personal information. The results of multiple regression analysis show the followings. The depression level of respondents turned out to be significantly higher in following groups: a group that experienced school bullying or violence, a group in which sleeping time is improper, a group in which subjective health status is bad, a group in which subjective happiness is lower, a group in which type A behavior pattern is higher, a group in which job seeking stress is higher, a group in which self esteem is lower, a group in which hopelessness is higher. Their explanatory power was 42.8%. The results indicate that the efforts to prevent bullying and violence experience, to get the proper amount of sleep, to be healthy, to increase subjective happiness and self esteem, to decrease type A behavior pattern, job seeking stress and hopelessness, are required to reduce the depression level of the college women of health affiliated educations.
Park, Man-Kyu;So, Sang-Ho;Lee, Jae-Yong;Lim, Jae-Han;Son, Myung-Hee;Kim, Byung-Chul
Journal of the Institute of Electronics Engineers of Korea CI
/
v.44
no.5
/
pp.38-48
/
2007
In ubiquitous environment, sensor networks that sense and transmit surrounding data without human intervention will become more important. If sensors are installed for detecting vehicles and measuring their speed in the road and that real-time information is given to drivers, it will be very effective for enhancing safety and controlling traffic in the road. In this paper, we proposed a new reliable and real-time sensor MAC protocol between AP and sensor nodes in order to provide real-time traffic flow information based on ubiquitous sensor networks. The proposed MAC allocates one TDMA slot for each sensor node on the IEEE 802.15.4 based channel structure, introduces relayed communication for distant sensors, and adopts a frame structure that supports retransmission for the case of errors. In addition, the proposed MAC synchronizes with AP by using beacon and adopts a hybrid tracking mode that supports economic power consumption according to various traffic situations, We implemented a simulator for the proposed MAC by using sim++ and evaluated various performances. The simulation results show that the proposed MAC reduces the power consumption and reveals excellent performance in real-time application systems.
Journal of agricultural medicine and community health
/
v.37
no.3
/
pp.156-166
/
2012
Objectives: This study aimed to identify the relationship among health-related quality of life of the Cheon-nam region elderly with low back pain. Methods: Data were obtained from cross-sectional surveys conducted as a part of the Community Health Survey 2008. The final analysis included data from 7,003 of the 7,070 elderly participants (aged over 65 years), as 67 responses were excluded since they were inaccurate. Data were analyzed with SPSS for Windows (ver. 19.0), using a ${\chi}^2$-test, a t-test, an ANOVA, and multiple liner regression. The significance threshold was set as p<0.05. Results: Factors related to the health-related quality of life of the elderly were low back pain, age, education level, occupation, subjective health status, subjective stress, drinking status, number of chronic diseases, and sleep duration. Further, health-related quality of life was significantly lower in elderly adults with low back pain. Conclusions: In order to improve health-related quality of life of the elderly and the development of the program for the management of low back pain will be needed to determine, it is considered necessary to study more to follow through the various analysis of in the elderly and health-related quality of life.
Kim, Jin-Su;Choi, Seong-Yong;Han, Seung-Jin;Choi, Jun-Hyeog;Rim, Kee-Wook;Lee, Jung-Hyun
Journal of the Institute of Electronics Engineers of Korea CI
/
v.45
no.6
/
pp.77-86
/
2008
Traditional cluster-based routing method is a representative method for increasing the energy efficiencies. In these cluster-based routing methods, the selected cluster head collect/aggregate the information and send the aggregated information to the base station. But they have to solve the unnecessary energy dissipation of frequent information exchange between the cluster head and whole member nodes in cluster. In this paper, we minimize the frequency of the information exchange for reducing the unnecessary transmit/receive frequencies as calculate the overlapped area or number of overlapped member nodes between the selected cluster head and previous cluster head in the setup phase. And besides, we consider the direction of super cluster head for optimal cluster formation. So, we propose the modified cluster selection scheme that optimizes the energy dissipation in the setup phase and reuses the saved energy in the steady phase efficiently that prolongs the whole wireless sensor network lifetime by uniformly selecting the cluster head.
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