• Journal of Biomedical Engineering Research
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• v.44 no.4
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• pp.275-283
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• 2023

The demand for skincare has increased due to the end of the COVID-19 pandemic, leading to a focus on skincare devices and technologies designed to improve the delivery of cosmetics. Among these technologies, skincare medical devices that utilize plasma therapy (Plasma) and sonophoresis (Sono) are commonly used in dermatology clinics. However, there is still a lack of quantitative analysis for transdermal absorption effects of Plasma and Sono skincare medical devices. In this study, we quantified enhanced transdermal absorption effects of Plasma and Sono devices through in-silico and ex-vivo studies. The Sono treatment demonstrated an increased transdermal absorption effect, showing a 10~13% difference in penetration compared to the control group in the in-silico experiment, and 159% and 184% increase in the ex-vivo experiment. The Plasma treatment revealed increased transdermal absorption effects, with a 1.0~2.5% penetration difference in the in-silico experiment, and a 124% increase in the ex-vivo experiment compared to the control group. We also observed a synergistic effect from the combined treatment of Plasma and Sono, as indicated by the highest increases of 197% and 242% in penetration. Furthermore, we have determined the optimal device settings and treatment conditions for Plasma-Sono skincare medical devices. Notably, higher on/off durations (Intensity levels) and longer Sono treatments resulted in greater transdermal absorption effects.

• Proceedings of the Membrane Society of Korea Conference
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• 1995.09a
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• pp.73-85
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• 1995

The asymmetric hollow fiber membranes were prepared by the wet spining of polyetherimide dope solution and the effect of hollow fiber structures on the permeation characteristics of carbon dioxide and nitrogen gases through these membrane were investigated. As the concentration of the $\gamma$-butyrolactone (GBL) in dope solution, acting as a swelling agent was increased, the structure of hollow fiber was changed from the finger to sponge type. The permeabilities of gases (CO$_{2}$, N$_{2}$) through these membrane were measured over the wide range of pressure under different temperature. The effect of water vapor on the permeabilities of gases was also investigated. The measured permeabilities showed the different characteristics depending on the structure of membranes. It was found that the flow through the pores were dominant over the polymers matrix. Blocking effect by water vapor in the pores of skin layer greatly improved the ideal separation factor of carbon dioxide/nitrogen.

• Journal of the Korean Society of Clothing and Textiles
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• v.21 no.7
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• pp.1153-1161
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• 1997

The insulation provided by clothing system is usually expressed in terms of a coo units and its distribution of the body, directly affect convective, conductive, and radiant heat loss from the skin to the environment Evaporated heat loss is dependent upon fabric permeability, the amount of body surface area covered by clothing, and the pumping of air between the body and garment layers. Persons at low to medium activity levels, dressed in conventional apparel in door environments, usually do not lose a large amount of heat through evaporation. Thermal manikin technology is used to measure the resistance to heat transfer provided by clothing systems. The reciprocal of this value, 6.45 W/m2.$^{\circ}C$ is often used in calculations for convenience. The purpose of this study was to implement a research program for calculation the insulation value (clo), body surface area and basal metabolic rate of selected clothing system. The project provided for the building of an insulation data base for use in evaluating and comparing new and improved garments.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.20 no.4
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• pp.309-332
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• 2016

Finite element method has been applied to solve the fundamental governing equations of natural convective, electrically conducting, incompressible fluid flow past an infinite vertical plate surrounded by porous medium in presence of thermal radiation, viscous dissipation, Soret and Dufour effects. In this research work, the results of coupled partial differential equations are found numerically by applying finite element technique. The sway of significant parameters such as Soret number, Dufour number, Grashof number for heat and mass transfer, Magnetic field parameter, Thermal radiation parameter, Permeability parameter on velocity, temperature and concentration evaluations in the boundary layer region are examined in detail and the results are shown in graphically. Furthermore, the effect of these parameters on local skin friction coefficient, local Nusselt number and Sherwood numbers is also investigated. A very good agreement is noticed between the present results and previous published works in some limiting cases.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.20 no.4
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• pp.355-374
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• 2016

This work is devoted to investigate heat and mass transfer effects on MHD natural convection flow past an inclined plate with ramped temperature numerically. The dimensionless governing equations for this investigation are solved by using finite element method. The effects of angle inclination, buoyancy ratio parameter, permeability parameter, magnetic parameter, Prandtl number, heat generation, thermal radiation, Eckert number, Schmidt number, chemical reaction parameter and time on velocity, temperature and concentration fields are studied and presented with the aid of figures. The effects of the pertinent parameters on skin friction, rate of heat transfer and mass transfer coefficients are presented in tabular form. The numerical results are compared graphically with previously published result as special case of the present investigation and results found to be in good agreement.

• Proceedings of the Korean Fiber Society Conference
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• 2001.10a
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• pp.115-118
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• 2001

The water vapour permeability of clothing materials is a critical property for clothing systems that must maintain thermal equilibrium for the wearer. The evaporation of perspiration provides the means of cooling the human body. The perspiration should evaporate from the surface of the skin and pass as water vapour through the clothing, which must be permeable for comfort. The primary objectives in this study of the transfer through fabrics of water vapour are to measure this property in a quantitative manner appropriate to clothing systems and to provide an increased understanding of various types of fabric in water vapour transfer. (omitted)

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2002.04a
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• pp.407-414
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• 2002

The knowledge of interaction of electromagnetic waves in composite structures is important for designing the shielding structure for antenna such as radome. Recently, radomes are constructed in the form of foam core sandwich structures that have many mechanical advantages such as high strength, long fatigue life, low density and adaptability to the intended function of structure. However, the propagation of electromagnetic waves is affected by high anisotropic permeability and loss tangent of the composite skin. In this study, the analytical model to understand the propagation of electromagnetic waves in the anisotropic composites and foam core sandwich structures with composite skins was proposed. Numerical analyses of unidirectional composites and foam core sandwich structure as a function of incident angle were performed. From the results of analysis, the general tendencies of transmittance of electromagnetic wave through composites and foam core sandwich structure were obtained.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.06a
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• pp.339-341
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• 2007

Soft ferromagnetic materials are very useful for many sensors using magnetic materials with high permeability, low coercivity and low hysteresis loss. Among them, FeCoSiBNi amorphous magnetic films show us a good impedance change(about 3.05%/Oe, at 12MHz) by the exterior magnetic field in this experiment. These are produced by rapid solidification from the melt and the material is ejected in a jet from a nozzle and quenched in a stream of liquid. After that, we make them a shape of wire with different sizes of width. Thus, we can find that the impedance change (122.16%, at 12MHz) is occurred and the fabricated magnetic wire has the characteristics of good sensor element.

• Polymer(Korea)
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• v.36 no.6
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• pp.705-711
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• 2012

In this study, the elastic liposome consisted of egg phospholipids and edge activator ($Tego^{(R)}$ care 450) was prepared in order to supplement the defect of the conventional liposome. We prepared elastic liposome containing quercetin, known as natural antioxidant, and evaluated the vesicles size, elasticity, loading efficiency, stability, and in vitro skin permeation. The mean diameter of quercetin loaded elastic liposome formulations ranged between 208.2~303.4 nm and loading efficiency was observed 64.1~87.5%. The highest loading efficiency (87.5%) and deformability (28.3) were observed at the optimal ratio of 90 : 10 (egg phospholipids : $Tego^{(R)}$ care 450) among 0.1% quercetin loaded elastic liposome formulations. The elastic liposome formulation was selected for further transdermal permeation study. The elastic liposome ($129.9{\mu}g/cm^2$) exhibited more skin permeability than general liposome ($114.8{\mu}g/cm^2$) and 1,3-butylene glycol ($75.1{\mu}g/cm^2$) solution. This results suggest that the elastic liposome formulation using $Tego^{(R)}$ care 450 as a major edge activator could be useful for the delivery of active ingredient through the skin transdermal.

• KSBB Journal
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• v.16 no.3
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• pp.253-258
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• 2001

Recently, there were many studies not only to enhance drug delivery effect but to reduce side effect. Drug delivery system(DDS) is able to improve efficiency with decreasing side effect of drug dosage. Among these application fields, DDS is often used as the method of drug dosage into the epidermic skin. We investigated characters of transdermal therapeutic system(TTS) and the skin permeability of that with applying DDS. We investigated the permeation of xanthan gum containing drug in rat skin using borizontal membrane cell model. Permeation properties of materials were investigated for water-soluble drug with oxiniacic acid and also for lipophilic drug with clofibrate. The permeation rate of lipophilic drug was found to be faster than that of water-soluble drug in vitro. The rate differences of both water-soluble drug and lipophilic drug according to drug content were negligible. We used glycerin, PEG 600 and oleic acid as enhancers. These results showed that skin permeation rate of each drug across the composite was mainly dependent on the property of base and chemical property of drug etc.. Proper selection of the polymeric materials which resemble and enhance properties of the delivering drug was found to be important in controlling the skin permeation rate. This result suggests a possible use of natural polymer base as a transdermal delivery system of antihyperlipoproteinemic agent.