• YAKHAK HOEJI
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• v.52 no.5
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• pp.355-360
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• 2008

In this study we investigated antioxidant activity of against several free radicals and skin whitening effect of 70% ethanol extract (leaf extracts and branch/stem mixed) of Lindera obtusiloba BL. Antioxidant activity was assessed by DPPH, superoxide radical and hydroxyl radical assays. The Lindera obtusiloba BL. extract had antioxidant activity dose dependently with an ${IC}_{50}$ value of 243.14 and 181.10 ${\mu}g$/ml for DPPH, 165.77 and >1500 ${\mu}g$/ml for non-enzymatic system of superoxide radical assay, 35.47 and >100 ${\mu}g$/ml for enzymatic system of superoxide radical assay, 1.21 mg/ml for hydroxyl radical assay. In addition we tested tyrosinase inhibition activity and melanin contents on B16 melanoma F10. B16 melanoma cell was treated by such sample as 1, 5, 10 and 50 ${\mu}g$/ml for 72 hr and tyrosinase inhibition was tested. Melanogenesis was inhibited to 22% at the dose of 50 ${\mu}g$/ml and tyrosinase was inhibited to 45.2% at the same dose. In conclusion Lindera obtusiloba BL had potent antioxidant activity and inhibitory activity of tyrosinase and melanin formation. It could be developed as the health functional food and functional cosmetic resources.

• Archives of Pharmacal Research
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• v.21 no.5
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• pp.503-507
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• 1998

Percutaneous absorption and model membrane variations of melationin (MT) in aqueous-based propylene glycol and $2-hydroxypropyl-{\beta}-cyclodextrin $vehicles were investigatted. the excised hairless mouse skin (HMS) and two synthetic ethylene vinyl acetate (EVA) and microporous polyethylene (MPE) were selected as a model membrane. the solubility of MT was determined by phase equilibrium study. the vertical $Franz{\circledR}$ type cell was used for diffusion study. The concentration of MT was determined using reverse phse HPLC system. The MT solubility was the highest in a mixture of PG and $2-HP{\beta}CD$. The percutaneous absorption of MT through excised HMS increased as the solubility increased. However, the permeability coefficient decreased and then slightly increased in mixture of PG and $2-HP{\beta}CD$. On the other hand, both flux and permeability coefficient through EVA membrane decreased as the solubility increased. No MT was detected over 12 h after starting diffusion through MPE membrane. The flux of MT was dependent on the type of membrane selected. Flux of MT was greatest in excised HMS followed by EBA and MPE membrane. Flux of MT through EVA membrane was 5-20 times lower when compared to excised HMS. Interestingly, volumes of donor phase when MPE membrane was used, significantly increased during the study period. the HMS might be applicable to expect plasma concentration of MT in human subjects based on flux and pharmacokinetic parameters as studied previously. the current studies may be applied to deliver MT transdermally using aqueous-based vehicles and to fabricate MT dosage forms.

• Journal of the Korean Dietetic Association
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• v.24 no.1
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• pp.31-47
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• 2018

The purpose of this research was to provide basic information for cookies made with black soybeans, chick peas, lentils, oatmeal, and brewer's yeast and to establish the optimum formula for the development of low glycemic index (GI) cookies with high biotin content for lactating women. This study was performed to determine the optimal composite recipe of oatmeal cookies with two different concentrations levels of bean powder (black soybeans, chick peas, lentils) and brewer's yeast using a central composite design. In addition, the mixing conditions of oatmeal cookies were optimized using response surface methodology of sensory evaluation and mechanical and physicochemical analysis. As a result, mechanical and physicochemical analyses showed significant values for lightness, redness, yellowness, hardness, and water content (P<0.05), while sensory evaluation showed significant values for flavor, taste, crispness, and overall acceptability (P<0.05). The optimal sensory combination was suggested to be 3.73 g of bean powder and 1.59 g of brewer's yeast. Considering all outcomes obtained throughout the experiments, brewer's yeast, black soybeans, chick peas, lentils, and oatmeal are suitable ingredients for increasing functionality and consumer acceptability of cookies. In addition, these results are expected to be useful in producing cookies of optimal quality, contributing to the development of various nutritious foods, and improving the food industry for lactating women.

• Journal of Digital Convergence
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• v.13 no.1
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• pp.525-533
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• 2015

This study presents a favoured pattern of makeup and psychology according to it by recognition type, through an examination of recognition for it in order to understand interest and awareness regarding it among female college students. The makeup is emotionally effective for confidence and positive thought, and is considered to be a category of social manner. The subjects can be grouped according to difference in recognition of makeup: contemplation, reception, observation and correspondence group. Although there is slight difference in the interest of four types of makeup depending on recognition difference, the behavior of makeup plays a large part in establishing personal relationships. The pattern of makeup favours natural style which places an emphasis on skin tone. The female college students in their 20s, who are at the center of current beauty trend market, were asked to conduct questionnaire of makeup, so interest and awareness of makeup behavior can be understand. If these findings are actively used in the beauty trend, various and effective beauty cultures are considered to be created.

• Physical Therapy Rehabilitation Science
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• v.9 no.1
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• pp.43-48
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• 2020

Objective: Breast cancer-related lymphedema (BCRL) is a major sequela after surgery or radiotherarpy for breast cancer. Manual lymphatic drainage (MLD) is designed to reduce lymph swelling by facilitating lymphatic drainage. This study attempted to determine the histologic changes in the skin and subcutaneous layer, and the immediate effect of MLD in decreasing lymphedema using ultrasound imaging, which is the method used most commonly to eliminate BCRL. Design: A single-group experimental study. Methods: Five subjects who were diagnosed with hemiparetic upper extremity lymphedema more than six months after breast cancer surgery participated in the study. MLD was performed for 60 minutes in the order of the thorax, breast, axilla, and upper arm of the affected side. In order to determine the effect of MLD, ultrasound imaging and limb volume were assessed. Two measurement tools were used for asessing lymphedema thickness among the pretest, posttest, and 30-minute follow-up period. Results: Significant diferences in ultrasound imaging and upper limb volume were found between the affected side and non-affected side (p<0.05). On the affected side, although ultrasound imaging showed a significant decrease after MLD (p<0.05), there were no significant difference in upper limb volume when compared to the baseline. Conclusions: In this study, a significant decrease in lymphedema by MLD was demonstrated by ultrasound imaging, which is considered to be more useful in assessing histological changes than limb volume measurements. Further research on the protocol for eliminating lymphedema will be needed.

• Korean Journal of Medicinal Crop Science
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• v.16 no.3
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• pp.173-182
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• 2008

Prunus sargentii of Rosaceae familiy, has been reported to have radical scavenging activity and anti-inflammatory effect. On these facts, this research was conducted to evaluate pharmaceutical activities of the bark extracts P. sargentii. Free radical scavenging activities of fraction (Fr) -5${\sim}$10 isolated from P. sargentii was higher than 80% respectively at 10ppm. The superoxide dismutase (SOD)-like activity of Fr-5, 9 were about 97, 84%, respectively at 1,000 ppm. Xanthine oxidase inhibitory effect of Fr-9, 10 were about 75, 78%, respectively at 1,000 ppm. The tyrosinase inhibitory effect related to skin-whitening was 72, 68% in Fr-2, 9 isolated from Prunus sargentii R. at 1,000 ppm. Hyaluronidase inhibition activity related to the anti-inflammation effect was 98% for Fr-8 at 500 ppm. Isolation of the methanol soluble fraction from P. sargentii yielded two major phenol compounds, (-)-epicatechin and taxifolin. The structure of the compound was certainly determined by chemical analyses, as well as NMR and Mass spectroscopy. The present study was carried out in a search for new cosmetic material from the bark from P. sargentii. and, (-)-epicatechin and taxifolin were isolated as active principles. So P. sargentii R. methanolic extracts may be used for the cosmetic material.

• Journal of the Korean Data and Information Science Society
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• v.25 no.6
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• pp.1273-1281
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• 2014

As a variety of industrial technology advances with various materials developed, cosmetics industry in general is witnessing many kinds of new cosmetic products. At the same time, Cosmetics Act becomes effective, and cosmetics ingredient labeling is implemented. Concerns with life pattern such as life management, biorhythm, right posture, and stress symptoms are on the increase in order to seek high-quality life as well. These life patterns are closely connected not only with life quality and health but with skin management, and thus this paper conducts a survey on the connection between functional cosmetics awareness and life pattern. Results show that out of 16 questions concerning cosmetics awareness, responses to question number 3, 5, 6 and 11 have relevant differences among colleges. Furthermore, the results of cross analysis with life pattern show that there are relevant differences between the year of responses and stress symptoms and between the year of responses and right posture. Lastly, it is shown that answers to questions regarding gender and biorhythm, gender and right posture, and gender and stress symptoms are relevantly different. Further research is needed to reveal the differences between college students and ordinary people at large.

• Journal of the Korean Institute of Landscape Architecture
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• v.15 no.3
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• pp.11-19
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• 1988

The purpose of this study is to investigate ways to control the wind dispersal of contton-wrapped seeds of such poplars and willows as Poplus alba, P. tomentiglandulosa, P. euramericana, P. deltoides, and Salix pseudo-lasiogyne. These trees are hated by many people because of their seeds blowing all over the place during May. These cottony seeds can be nuisance to various types of outdoor activities, pose safely threat to drivers, become fire hazards during prolonged spring dry spells, and cause many types of health hazards of allergy such as sneezing. rhinitis, asthma, and skin rashes. Four control methods can be used to resolve the problem. First, pruning can be a solution, but it is unsatisfactory in terms of costs and outcome. Second, planting of male trees only can be a solution, but it is hard to identify sexes of saplings. Third, female trees can he replaced with other species. But it requires high costs and takes at least ten years to functionally replace the removed ones. As an alternative to such unsatisfactory control methods, the possibility of applying plant growth regulators has been investigated since 1983. During the pre-test, various concentrations and mixtures of them were either sprayed or injected, but failed to achieve any promising results. But the injection of a mixture made up of 0.75g of 2-chloroethane phosphonic acid with 0.2 mg of GA in 300cc water in the end of March produced premature falling of almost all aments and capsules of treated poplars and willows. It was found that the effect of the injection lasts two years. The results of the main experiment of 1987 can be summarized as follows ; First, the injection of the mixture of 2-chloroethane phosphonic acid and GA increases the premature abscisin of aments and capsules, thus reducing the wind dispersal of the cottony seeds of S. pseudolasiogyne, P. tomentiglandulosa, and P. euramericana 1644.09, 1200.61, and 1485.11 times, respectively, than that of the naural abscisin, It is estimated that the average number of wind-blown seeds reduced are approximatively 6,185,100, 4062,900, and 2,830,670 per tree, respectively. Second, the treatment causes no observable side effects on the growth of the samples tested.

• Archives of Plastic Surgery
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• v.45 no.3
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• pp.284-288
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• 2018

Dynamic infrared thermography (DIRT) has been used for the preoperative mapping of cutaneous perforators. This technique has shown a positive correlation with intraoperative findings. Our aim was to evaluate the accuracy of perforator mapping with DIRT and augmented reality using a portable projector. For this purpose, three volunteers had both of their anterolateral thighs assessed for the presence and location of cutaneous perforators using DIRT. The obtained image of these "hotspots" was projected back onto the thigh and the presence of Doppler signals within a 10-cm diameter from the midpoint between the lateral patella and the anterior superior iliac spine was assessed using a handheld Doppler device. Hotspots were identified in all six anterolateral thighs and were successfully projected onto the skin. The median number of perforators identified within the area of interest was 5 (range, 3-8) and the median time needed to identify them was 3.5 minutes (range, 3.3-4.0 minutes). Every hotspot was correlated to a Doppler sound signal. In conclusion, augmented reality can be a reliable method for transferring the location of perforators identified by DIRT onto the thigh, facilitating its assessment and yielding a reliable map of potential perforators for flap raising.

• The Journal of Korean Physical Therapy
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• v.16 no.1
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• pp.70-84
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• 2004

This study was carried out to evaluate the body fat breakdown during topical seaweed extract treatment and in combination with the iontophoresis, phonophoresis method to enhance skin absorption of lipolytic compounds. Of 24 female obesity subjects, 7 treated a gel types of seaweed extract only(control group) and 10 treated in combination with the iontophoresis(experimental group I) and 7 treated in combination with the phonophoresis(experimental group II). Topical treatment of each sample was designed for 2 weeks, treated with 2 times a day about $10m{\ell}$ on the abdomen, triceps, thigh and superior ilium, respectively. Experimental group treat with the iontophoresis and phonophoresis during 5 minutes immediately after topical treatment. After one and two weeks of topical treatment, measured body weight, body fat, skinfolds thickness respectively. Then venous blood samples were taken and analyzed serum lipids. The results were as follows; 1) There were decrement of body weight, $\%$ of body fat, superior ilium, triceps and thigh thickness between pre and post treatment in all group. Especially, there were more decrement of body weight, $\%$ of body fat in the iontophoresis treated group. 2) There were decrement in total CHOL, LDL, TRIG and increment in HDL in all group. These phenomena were predominant in the iontophoresis treated group. CHOL decrement in the experimental group were significant after two weeks iontophoresis treatment.