한국약용작물학회지 (Korean Journal of Medicinal Crop Science)

  • 제16권3호
  • /
  • Pages.173-182
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  • 2008
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  • 1225-9306(pISSN)
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  • 2288-0186(eISSN)
한국약용작물학회 (The Korean Society of Medicinal Crop Science)
권호 표지

산벚나무 수피추출물의 생리활성 및 페놀성 화합물 분리

Biological Activity Investigation, and Phenol Compounds Isolation from Barks of Prunus Sargentii R.

  • 박정미 (대구한의대학교 화장품약리학과) ;
  • 이진영 (대구한의대학교 화장품약리학과) ;
  • 박태순 (대구한의대학교 화장품약리학과) ;
  • 박근혜 (대구한의대학교 화장품약리학과) ;
  • 박강수 (대구한의대학교 화장품약리학과) ;
  • 김태훈 (대구한의대학교 한약재약리학과) ;
  • 조영제 (경북대학교 식품공학과) ;
  • 권오준 (경북전략산업기획단) ;
  • 최경임 (대구보건대학 뷰티코디네이션과) ;
  • 안봉전 (대구한의대학교 화장품약리학과)
  • Park, Jung-Mi (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Lee, Jin-Young (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Tae-Soon (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Gun-Hye (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Park, Kang-Soo (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Kim, Tae-Hoon (Department of Herbal Medicinal Phamacology, Daegu Haany University) ;
  • Cho, Young-Je (Department of Food Engineering, Kyungpook National University) ;
  • Kwon, O-Jun (Gyeongbuk Regional Innovation Agency) ;
  • Choi, Kyung-Im (Department of Beauty Coordination, Daegu Health College) ;
  • An, Bong-Jeun (Department of Cosmeceutical Science, Daegu Haany University)
  • 발행 : 2008.06.30
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초록

Prunus sargentii of Rosaceae familiy, has been reported to have radical scavenging activity and anti-inflammatory effect. On these facts, this research was conducted to evaluate pharmaceutical activities of the bark extracts P. sargentii. Free radical scavenging activities of fraction (Fr) -5${\sim}$10 isolated from P. sargentii was higher than 80% respectively at 10ppm. The superoxide dismutase (SOD)-like activity of Fr-5, 9 were about 97, 84%, respectively at 1,000 ppm. Xanthine oxidase inhibitory effect of Fr-9, 10 were about 75, 78%, respectively at 1,000 ppm. The tyrosinase inhibitory effect related to skin-whitening was 72, 68% in Fr-2, 9 isolated from Prunus sargentii R. at 1,000 ppm. Hyaluronidase inhibition activity related to the anti-inflammation effect was 98% for Fr-8 at 500 ppm. Isolation of the methanol soluble fraction from P. sargentii yielded two major phenol compounds, (-)-epicatechin and taxifolin. The structure of the compound was certainly determined by chemical analyses, as well as NMR and Mass spectroscopy. The present study was carried out in a search for new cosmetic material from the bark from P. sargentii. and, (-)-epicatechin and taxifolin were isolated as active principles. So P. sargentii R. methanolic extracts may be used for the cosmetic material.

키워드

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