• 대한화장품학회지
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• 제23권3호
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• pp.48-74
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• 1997

Retinlyl Palmitate, the skin normalizerm is useful to promote greater skin elasticity, to diminish lipid peroxidation and skin roughness following UV exposure, and promote a youthfulgeneral skin appearance. In manufacturing creams, Retinyl Palmitate, which is a derivative of retinol, is used since reionol is easily oxidized by heat and light. However, only a small mount of retinol, is used since using a large amount of it may be harmful to its stability. In this study, thermal stability and UV stability of W/O-, W/S-, O/W-, and MLV-type creams containing 5% of retinyl palmitate and 10% of tocopheryl acetate are measured by Chroma Meters, and the content of RP is quantitatively analyzed by HPLC at 25 $^{\circ}C$ and 45 $^{\circ}C$. Also, how RP has been changed by heat, light, etc. is measured by HPLC, and toxicity of the changed substance is studied. Particle size of each type of the cream if measured, cellular renewal is measured by using DHP and Chroma Meters in order to study their efficacy and effect, moisture content is measured by using Corneometer and Tewameter, and how much wrinkles are improved is studied by using Image Analyzer. Development of MLV-type cream containing 5% of RP and 10% of TA, and satisfying conditions for better creams has been successful.

• 대한화장품학회지
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• 제22권1호
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• pp.40-59
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• 1996

Retinol은 열과 빛에 쉽게 산화되기 때문에 그 유도체인 Retinyl Palmitate를 사용하고 있으나 이것 또한 안정성이 우려되어 많은 양을 사용하지 못하고 있다. 본 연구에서는 Retinyl Palmitate 5% 와 Tocopgeryl Acetate 10%를 함유한 W/O, W/S, O/W, MLV Type의 크림에서 열적 안정성 및 UV 안정성을 CHROMA METERS로 측정하였으며, $25^{\circ}C$, $45^{\circ}C$에서 RP의 함량을 HPLC로 정량 분석하였다. 또한 RP가 열, 빛 등에 의해서 어떤 물질로 변화하였는지를 측정하였으며, 변화된 물질의 독성에 대한 연구를 하였다. 각각의 크림 TYPE 마다 입자 SIZE를 측정했으며, DNA와 CHROMA METERS를 사용하여 CELLULAR RENEWAL을 측정하였다.

• 동의생리병리학회지
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• 제25권4호
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• pp.755-758
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• 2011

Sasang Constitutional Medicine (SCM) suggests the concept of health condition which is owned of different properties by each Sasang Constitution. But SCM theory has concentrate to explaining different symptoms that distinguish health condition, not much concerned with practical methods like face features, pulse diagnosis, skin surface properties and voice features. Physical properties of practical diagnosis methods from literature finding have been researched. As a result, complexion and face moisture were described to be physical properties related to health State. In scope of pulse diagnosis, depth, rate, contour, width and pressure are related. Skin surfaces' elasticity, moisture, fraction properties were also suggested as factors of health State of Sasang Constitution. We assume that this study would contribute further studies for objectifying and quantifying diagnosis methods to evaluate health state grades of Sasang Constitution.

• Journal of Oral Medicine and Pain
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• 제32권4호
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• pp.421-429
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• 2007

최근 tactile sensor 를 사용하여 근육의 경도와 탄성도를 조사하는 방법이 저작근의 새로운 평가방법으로 제시되고 있다. 본 연구의 목적은 촉각센서를 이용하여 일정시간 껌씹기를 시행전, 중, 후의 저작근의 경도와 탄성도를 조사하여 향후 턱관절 장애 환자의 저작근 평가를 위한 기초자료를 확보하는 데 있다. 건강한 성인 8명을 대상으로 양측 전측두근(anterior temporalis), 하교근(inferior masseter)의 경도와 탄성도를 촉각센서 (Venustron II, Axion Co., Japan)를 이용하여 다음과 같이 측정하였다. 피검자들을 unit-chair에 바로 앉힌 상태에서 양측 교근 및 측두근 부위를 촉진을 통해 전 측두근(temporalis anterior), 하 교근(masseter inferior) 두 부위를 펜으로 표시하였다. 실험의 재현성을 위하여 투명한 종이에 ala-tragus line을 표시한 후 두 부위를 투명종이 위에 표시하였다. 편안한 상태에서 촉각센서를 사용하여 양측 하 교근 및 전 측두근의 경도와 탄성도를 측정한 후, 껌(Excellent Breath, Taiyo Co., Japan)을 양측으로 씹게 하여 1초당 2회의 속도로 씹게 하였다. 껌을 40분동안 저작하는 동안 10분, 20분, 30분, 40분에 양측 하 교근 및 전 측두근의 경도와 탄성도를 측정하였다. 그 후 껌을 뱉게 하고 하악의 안정위 상태에서 10분, 20분, 30분, 40분 후 양측하 교근 및 전 측두근의 경도와 탄성도를 각각 측정하였다. 측정치들을 반복측정 이원분산분석과 다중비교를 통하여 비교하였다. 실험결과 측두근과 교근을 비교 시 탄성도, 경도 모두 교근의 변화가 유의하게 크다. 또한 저작하면 서서히 경도는 증가하며 탄성도는 반대로 감소한다. 탄성도 및 경도는 저작 시 신속히 증가하나 저작 종료 후에는 탄성도만 신속히 회복되나 경도는 약 10분 이상의 일정시간이 지나야 회복된다. 이상의 결과들을 보아 임상적으로 좀 더 다양한 연구와 기초자료가 확보된다면, 저작근의 근육 상태를 평가하는데, 근육의 탄성도와 경도를 조사하는 tactile sensor system은 유익한 기기로서 활용될 수 있을 것이다.

• Archives of Plastic Surgery
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• 제39권5호
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• pp.457-462
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• 2012

Background The elasticity of the back skin of the rat reduced the tension around wounds during the wound healing process in that region, and thus activates wound contraction. The authors proposed two skin fixation methods using readily available materials to decrease the influence of wound contraction on wound healing and designed an experiment to determine their effects. Methods The authors made 36 skin wounds on the backs of 18 rats, and they divided them into three groups. Each group was treated with three different kinds of dressing materials, each with different skin fixing characteristics. Group A was a control group. Group B and group C were dressed by the first and the second skin fixation method. We measured the areas of the wounds post-surgically and calculated the wound area reduction rates. Results The two skin fixation methods both reduced the effect of wound contraction compared to the control group. Each of the two methods had different outcomes in reducing wound contraction. Conclusions The experiment demonstrated significant differences among the wound areas and the wound area reduction rates of the three groups as a result of differences in the degree of wound contraction. To obtain accurate results from wound healing experiments, appropriate skin fixation methods must be adopted.

• Journal of Ginseng Research
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• 제44권1호
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• pp.115-122
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• 2020

Background: In aged skin, degradation of collagen fibers, which occupy the majority of the extracellular matrix in the dermis, and changes of aquaporin 3 (AQP3) and skin constituents, such as hyaluronic acid and ceramide, cause wrinkles and decrease skin moisturization to contribute to dryness and lower elasticity skin. Red ginseng (RG) is used as a cosmetic and food material and is known to protect from UVB-induced cell death, increase skin hydration, prevent wrinkles, and have an antioxidative effect. But, in general, RG used as a material is the soluble liquid portion in the solvent, and the part that is not soluble in the solvent is discarded. Thus, we made the whole RG into microgranulation and dispersed in water to produce gel form for using entire RG, and it was named red ginseng NaturalGEL (RG NGEL). Methods: RG NGEL was investigated for matrix metalloproteinases inhibitory activity, induction of Type I collagen, AQP3, hyaluronan synthetase 2, serine palmitoyl transferase, ceramide synthase 3, and filaggrin expression and compared with RG water extract. Results: RG NGEL reduced the levels of UV-induced matrix metalloproteinases and increased Type I collagen in human fibroblast cells and upregulated AQP3, hyaluronan synthetase 2, serine palmitoyl transferase, ceramide synthase 3, and filaggrin expressions in human keratinocytes compared with RG water extract. Conclusion: RG NGEL has the potential as an effective reagent for antiaging cosmetics to improve wrinkle formation and skin hydration.

• 한국식생활문화학회지
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• 제23권2호
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• pp.258-267
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• 2008

The purpose of this study was to investigate the effects that body composition, nutrient intake, and biochemical indices have on skin status, as well as their associations with skin health status, by assessing 44 female university students. The subjects were classified into 3 groups according to skin sensitivity: sensitive skin (n=11), slightly sensitive skin (n=24), and normal skin (n=9). The study included anthropometric measurements and body composition analyses, dietary intake evaluations, blood chemical analyses, and skin health status assessments. Based on % body fat, the results indicated the subjects were moderately obese (29.6%). Obesity indices were not different among the groups, but the sensitive skin group tended to have higher skinfold thickness. Dry skin was determined as the skin type of all subjects. In the sensitive skin groups, U-zone and T-zone sebum were significantly lower (p<0.05), and spots were significantly higher (p<0.05) than in the normal skin group. In terms of nutrient intakes, the sensitive skin groups consumed significantly lower amounts of P and vitamins A and E (p<0.05). There were no significant differences in serum lipid fractions or total antioxidant status among the groups. In correlation coefficients analysis, skin elasticity had significant negative correlations with subscapular and midaxillary skinfold thickness, body protein, and body minerals (p<0.05). Wrinkling had positive correlations with triceps and thigh skinfold thickness (p<0.05). Skin evenness had negative correlations with energy intake, vitamins A, $B_1,\;B_2$, C, E, niacin, and zinc (p<0.05), as well as folate and P (p<0.01) and vitamin $B_6$ (p<0.001). A similar correlation tendency was observed for spots and nutrient intake, showing negative correlations with vitamins A, $B_6$, and E, as well as folate, Fe, and P. U-zone sebum showed significant positive correlations with serum levels of total cholesterol and triglycerides. From these findings, skin health status appears to be affected by both nutrient intake and body composition. Therefore, having a proper balance between dietary intake and body composition may influence skin health status in females with sensitive skin.

• 한국양식학회지
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• 제9권4호
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• pp.363-375
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• 1996

천연 astaxanthin 색소를 다량 함유한 phaffia 효모를 양식 어류에게 공급하였을 때, 이 색소가 어류의 성장과 소화, 흡수되는 정도를 조사하기 위하여 이스라엘 잉어($650{\pm}20$ g), 비단잉어($80{\pm}10$ g) 및 나일틸라피아($200{\pm}20$ g)의 사료에 phaffia 효모를 $10\%$ 첨가하여 10주간 공급한 다음 성장률, 체조성, 근육의 탄력도 및 근육 색과 체색 등의 변화를 측정하였다. Phaffia 효모 첨가 사료에 대한 효모 대조구로서 $10\%$의 맥주 효모 첨가 사료구를, 그리고 이들 두가지 반정제 효모 사료에 대한 성장 대조구로서 시판 상품 사료구를 설정하여 10주간 사육한 결과 이스라엘 잉어, 비단잉어 및 틸라피아의 성장에는 모든 사료 공급구에서 유의적인 차이가 없었다(P>0.05). 이들 실험어의 근육 내의 일반 성분은 실험 후에도 현저한 차이가 나타나지 않아(P>0.05), phaffia 효모나 맥주 효모 사료가 체성분 조성에는 영향이 없는 것으로 나타났다. 또한 횟감으로 이용되는 어종인 이스라엘 잉어와 틸라피아의 근육에 쫄깃한 정도를 나타내는 기계적 탄력도와 관능적 탄력도를 측정한 결과 모두 유의적인 차이는 나타나지 않았다(P>0.05). 실험어의 근육에 phaffia 효모에서 유래되는 붉은 색소의 침착은 이스라엘 잉어와 비단잉어 실험구에서는 근육내의 색소 분석과 관능적 측정 실험 모두에서 현저하게 높게 나타났지만(P<0.05), 틸라피아에서는 색소 분석과 관능적 측정 실험 모두에서 유의적인 차이가 나타나지 않았다(P>0.05).

• 융합정보논문지
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• 제11권2호
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• pp.194-200
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• 2021

본 연구의 목적은 6주간 중년여성을 대상으로 SUKI 중재 프로그램이 윗입술근피에 미치는 영향에 대해 알아보고자 진행되었다. 실험대상자는 총 20명이었으며, 6주간 주 3회 씩 안면부의 윗입술 근피에 대한 Pattern T1, Pattern T2, Pattern T3, Pattern T4의 SUKI 중재프로그램을 실시하였고, 결과는 다음과 같았다. 윗입술근피의 군내 비교에서는 일부이지만 실험군에서 유의한 차이가 있었다. 따라서, SUKI 중재 프로그램이 윗입술근피의 탄력 향상에 일부 도움을 줄 수 있는 것으로 나타났다(p<.05). 본 연구에서는 제한적이지만, 중년여성의 안면부에 위치하고 있는 윗입술근피의 탄력 감소 문제가 입 주위에 각종 주름을 발생시켜 여성의 외모에 대한 자신감을 잃게 하고 있다는 것을 근간으로 SUKI 중재 프로그램을 활용하였다. 또한 이것은 정상적인 안면근피가 영향을 끼치는 용모에 대한 의미로서, 중년여성의 생애주기에 맞는 적정한 안면근피의 관리에 의한 용모관리를 할 수 있는 일부방법을 제시하고자 하였다. 결론적으로 추후 다양한 실험자들에게 여성의 얼굴 피부미용과 주름을 예방하고 입 주위 안면근피의 탄력향상에 도움을 줄 수 있는 방법에 대한 새로운 연구자료로 활용될 수 있기를 기대하고자 한다.

• 한국패션뷰티학회지
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• 제5권3호
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• pp.111-117
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• 2007

Essential oils aims to rejuvenate and beautify medical skin care the body through the use of essential oils, and generally to improve our outward appearance. Much of this section fouses on the different methods by which essential oils can be used to improve the complexion or to treat specific medical care skin conditions. Beauty, however, is not just skin-deep. The condition of the medical care express the overall health of an individual. A relaxed attitude, together with a well-balanced diet, enough exercise, and a daily intake of plenty of spring water or herbal teas, all help to keep the system in top condition. Essential oils is a healing art which has powerful effects on both mind and body. The vital element in essential oils is the pure oils which are extracted from various part of different plants. The key to medical aromatherapy care lies in its dual use of essential oils and medical care massage, thus masking full use of two of our most important senses-smell and touch. Medical aromatherapy care is holistic, working mainly on the nervous system and including the head and body as part of the same treatment. Using pressure points along the spine, Medical aromatherapy care on the autonomic nervous system and has an immediate effect of relexation. In directly it also acts on mood. Many of the medical massage movements help lymphatic drainage. Essential oils have many different qualities; they can be relaxing or invigorating and are generally antisepic and antibacterial. Medical aromatherapy care can have psychological benefits. The power of essences in healing has been recognized in the treatment of insect bites. Clove, thyme, sandalwood, and lavender are a few of the essences that have antiseptic. Essential oils effect the dry skin for small visual pores, dull matte finish, rough sandy feeling, tantskin. Essential oils effect the mature/sun damaged skin for some red or couperose areas, loose saggy skin, exposure to a lot of ultraviolet light. Essential oils effect the medical care nomal skin good elasticity, healthy color(good circulation), smooth terture.