Effect of red ginseng NaturalGEL on skin aging |
Kim, Ye Hyang
(Efficacy Research department, Natural Products and Materials Research Institute, SK Bioland)
Park, Hye Rim (Efficacy Research department, Natural Products and Materials Research Institute, SK Bioland) Cha, So Yoon (Efficacy Research department, Natural Products and Materials Research Institute, SK Bioland) Lee, So Hun (Efficacy Research department, Natural Products and Materials Research Institute, SK Bioland) Jo, Jung Wung (Efficacy Research department, Natural Products and Materials Research Institute, SK Bioland) Go, Jung Nam (Efficacy Research department, Natural Products and Materials Research Institute, SK Bioland) Lee, Kang Hyuk (Efficacy Research department, Natural Products and Materials Research Institute, SK Bioland) Lee, Su Yeon (Efficacy Research department, Natural Products and Materials Research Institute, SK Bioland) Shin, Song Seok (Efficacy Research department, Natural Products and Materials Research Institute, SK Bioland) |
1 | Kim N, Koo B, Lee S, Hwang E, So S, Do J. Effect of Korean red ginseng on collagen biosynthesis and MMP-I activity in human dermal fibroblast. J Ginseng Res 2007;31:86-92. DOI |
2 | Lee EH, Cho SY, Kim SJ, Shin ES, Chang HK, Kim DH, Yeom MH, Woe KS, Lee J, Sim YC, et al. Ginsenoside F1 protects human HaCaT keratinocytes from ultraviolet-B-induced apoptosis by maintaining constant levels of Bcl-2. J Invest Dermatol 2003;121:607-13. DOI |
3 | Kim S, Kang BY, Cho SY, Sung DS, Chang HK, Yeom MH, Kim DH, Sim YC, Lee YS. Compound K induces expression of hyaluronan synthetase 2 gene in transformed human keratinocytes and increases hyaluronan in hairless mouse skin. Biochem Biophys Res Commun 2004;316:348-55. DOI |
4 | Kim H, Oh I, Park KH, Kim NM, Do JH, Cho Y. Stimulatory effect of dietary red ginseng on epidermal hydration and ceramide levels in ultraviolet irradiated hairless mice. J Med Food 2009;12:746-54. DOI |
5 | Sung HS, Yoon SK, Kim WJ, Yang CB. Relationship between chemical components and their yields of red ginseng extract by various extracting conditions. Korean J Ginseng Res 1988;9:170-8. |
6 | Choi JH, Kim CM, Choi IH. A study on improving egg freshness using red ginseng marc powder to laying hens. J Environmental Science International 2015;24:1233-7. DOI |
7 | Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: a key molecule in skin aging. Dermatoendocrinol 2012;4:253-8. DOI |
8 | Yaar M, Gilchrest BA. Photoageing: mechanism, prevention and therapy. Br J Dermatol 2007;157:874-87. DOI |
9 | Jang YA, Lee JT. Anti-wrinkle effect of berberine by inhibition of MMP-2 and MMP-9 activity in fibroblasts. J Appl Biol Chem 2018;61:9-15. DOI |
10 | Evrosimovska B, Velickovski B, Dimova C, Veleska-Stefkovska D. Matrix metalloproteinases (with accent to collagenases). J Cell Anim Biol 2011;5:113-20. |
11 | Chiang HM1, Chen HC, Chiu HH, Chen CW, Wang SM, Wen KC. Neonauclea reticulata (Havil.) Merr stimulates skin regeneration after UVB exposure via ROS Scavenging and Modulation of the MAPK/MMPs/Collagen pathway. Evid Based Complement Alternat Med 2013;2013:1-9. |
12 | Quan T, Little E, Quan H, Qin Z, Voorhees JJ, Fisher GJ. Elevated matrix metalloproteinases and collagen fragmentation in photodamaged human skin: impact of altered extracellular matrix microenvironment on dermal fibroblast function. J Invest Dermatol 2013;133:1362-6. |
13 | Fisher GJ1, Wang ZQ, Datta SC, Varani J, Kang S, Voorhees JJ. Pathophysiology of premature skin aging induced by ultraviolet light. N Engl J Med 1997;337:1419-28. DOI |
14 | Jung YR, Kim DH, Kim SR, An HJ, Lee EK, Tanaka T, Kim ND, Yokozawa T, Park JN, Chung HY. Anti-wrinkle effect of magnesium lithospermate B from Salvia miltiorrhiza BUNGE: inhibition of MMPs via NF-kB signaling. PLoS One 2014;9:e102689. DOI |
15 | Pandel R, Poljsak B, Godic A, Dahmane R. Skin photoaging and the role of antioxidants in its prevention. ISRN Dermatol 2013;2013:1-11. DOI |
16 | Kasamatsu S, Hachiya A, Fujimura T, Sriwiriyanont P, Haketa K, Visscher MO, Kitzmiller WJ, Bello A, Kitahara T, Kobinger GP, et al. Essential role of microfibrillar-associated protein 4 in human cutaneous homeostasis and in its photoprotection. Sci Rep 2011;1:1-10. DOI |
17 |
Sun H, Liu C, Zhang AH, Han Y, Yan GL, Wang P, Wang XJ. Rapid discovery and global characterization of multiple constituents from Kai-Xin-San using an integrated |
18 | Xiu Y, Ma L, Zhao H, Sun X, Li X, Liu S. Differentiation and identification of ginsenoside structural isomers by two-dimensional mass spectrometry combined with statistical analysis. J Ginseng Res 2017:1-9. |
19 | Gelse K1, Poschl E, Aigner T. Collagensestructure, function, and biosynthesis. Adv Drug Deliv Rev 2003;55:1531-46. DOI |
20 | Farage MA, Miller KW, Elsner P, Maibach HI. Intrinsic and extrinsic factors in skin ageing: a review. Int J Cosmet Sci 2008;30:87-95. DOI |
21 | Pittayapruek P, Meephansan J, Prapapan O, Komine M, Ohtsuki M. Role of matrix metalloproteinases in photoaging and photocarcinogenesis. Int J Mol Sci 2016;17:E868. |
22 | Rabe JH1, Mamelak AJ, McElgunn PJ, Morison WL, Sauder DN. Photoaging: mechanisms and repair. J Am Acad Dermatol 2006;55:1-19. DOI |
23 | Fisher GJ, Datta SC, Talwar HS, Wang ZQ, Varani J, Kang S, Voorhees JJ. The molecular basis of sun-induced premature skin aging and retinoid antagonism. Nature 1996;379:335-8. DOI |
24 | Hoste E, Kemperman P, Devos M, Denecker G, Kezic S, Yau N, Gilbert B, Lippens S, De Groote P, Roelandt R, et al. Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin. J Invest Dermatol 2011;131:2233-41. DOI |
25 |
Xiu Y, Zhao H, Gao Y, Liu W, Liu S. Chemical transformation of ginsenoside Re by a heteropoly acid investigated using |
26 | Fisher GJ, Wang Z-Q, Datta SC, Varani J, Kang S, Voorhees JJ. Pathophysiology of premature skin aging induced by ultraviolet light. N Engl J Med 1997;337:1419-28. DOI |
27 | Varani J, Warner RL, Gharaee-Kermani M, Phan SH, Kang S, Chung JH, Wang ZQ, Datta SC, Fisher GJ, Voorhees JJ. Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin. J Invest Dermatol 2000;114:480-6. DOI |
28 | Borodzicz S, Rudnicka L, Mirowska-Guzel D, Cudnoch-Jedrzejewska A. The role of epidermal sphingolipids in dermatologic diseases. Lipids Health Dis 2016;15:1-9. DOI |
29 | Cha HJ, He C, Zhao H, Dong Y, An IS, An S. Intercellular and intracellular functions of ceramides and their metabolites in skin. Int J Mol Med 2016;38:16-22. DOI |
30 | Sandilands A, Sutherland C, Irvine AD, McLean WH. Filaggrin in the frontline: role in skin barrier function and disease. J Cell Sci 2009;122:1285-94. DOI |
31 | Li J, Tang H, Hu X, Chen M, Xie H. Aquaporin-3 gene and protein expression in sun-protected human skin decreases with skin ageing. Australas J Dermatol 2010;51:106-12. DOI |
32 | Hara M, Verkman AS. Glycerol replacement corrects defective skin hydration, elasticity, and barrier function in aquaporin-3-deficient mice. Proc Natl Acad Sci U S A 2003;100:7360-5. DOI |
33 | Lee MY, Kim BA, Yang JC. Effects of extracts derived from red ginseng residue on antioxidant activity and elastase inhibition. J Kor Oil Chem Soc 2016;33:658-66. DOI |
![]() |