• Title/Summary/Keyword: single hill

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The Measurement and Analysis of Cost Error in Simulated Annealing (시뮬레이티드 어닐링에서의 비용오류 측정 및 분석)

  • Hong, Cheol-Ui;Kim, Yeong-Jun
    • The Transactions of the Korea Information Processing Society
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    • v.7 no.4
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    • pp.1141-1149
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    • 2000
  • This paper proposes new cost error measurement method and analyzes the optimistic and pessimistic cost errors statistically which is resulted from an asynchronous parallel Simulated annealing (SA) in distributed memory multicomputers. The traditional cost error measurement scheme has inherent problems which are corrected in the new method. At each temperature the new method predicts the amount of cost error that an algorithm will tolerate and still converge by the hill-climbing nature of SA. This method also explains three interesting phenomenon of he cost error analytically. So the new cost error measurement method provides a single mechanism for the occurrence of cost error and its control.

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Reduction of sidelobe levels in multicarrier radar signals via the fusion of hill patterns and geometric progression

  • Raghavendra, Channapatna Gopalkrishna;Prakash, Raghu Srivatsa Marasandra;Panemangalore, Vignesh Nayak
    • ETRI Journal
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    • v.43 no.4
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    • pp.650-659
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    • 2021
  • Multi-carrier waveforms have several advantages over single-carrier waveforms for radar communication. Employing multi-carrier complementary phase-coded (MCPC) waveforms in radar applications has recently attracted significant attention. MCPC radar signals take advantage of orthogonal frequency division multiplexing properties, and several authors have explored the use of MCPC signals and the difficulties associated with their implementation. The sidelobe level and peak-to-mean-envelope-power ratio (PMEPR) are the key issues that must be addressed to improve the performance of radar signals. We propose a scheme that applies pattern-based scaling and geometric progression methods to enhance sidelobe and PMEPR levels in MCPC radar signals. Numerical results demonstrate the improvement of sidelobe and PMEPR levels in the proposed scheme. Additionally, autocorrelations are obtained and analyzed by applying the proposed scheme in extensive simulation experiments.

A Preliminary Study of Roller Types for Chip Seals Construction (Chip Seals 시공을 위한 롤러 종류에 따른 기초적인 연구)

  • Lee, Jae-Jun;Kim, R. Young-Soo
    • International Journal of Highway Engineering
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    • v.12 no.3
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    • pp.79-85
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    • 2010
  • This paper presents a preliminary study of roller types for chip seals based on aggregate retention performance. Chip seal test sections composed of single seals of granite 78M aggregate and CRS-2 emulsion were constructed using three different roller types: the pneumatic tire roller, steel wheel roller, and combination roller. In order to investigate the performance of these rollers effectively, it is critical to test chip seal samples obtained directly from field construction. Therefore, test sections were constructed on New Sandy Hill Church Road near Bailey, North Carolina. Chip seal samples obtained from these sections were used for laboratory testing. The aggregate retention performance was evaluated using the flip-over test (FOT), Vialit test, and the third-scale Model Mobile Loading Simulator (MMLS3). Based on the test results and visual observation, both the pneumatic roller and the combination roller used together are recommended to improve chip seal performance with the sequence of the pneumatic roller rolling first followed by the combination roller.

Activation of ATP-sensitive Potassium Channels by the Predominant Metabolite of Isoflurane in Rabbit Ventricular Myocytes

  • Han, Jin;Kim, Na-Ri;Kim, Eui-Yong;Kim, Sung-Ju;Cho, Kang-Hee
    • The Korean Journal of Physiology and Pharmacology
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    • v.5 no.2
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    • pp.165-175
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    • 2001
  • Background: Recent in vivo experimental evidence suggests that isoflurane-induced cardioprotection may involve $K_{ATP}$ channel activation. However, it was demonstrated that isoflurane inhibited $K_{ATP}$ channel activities in the inside-out patch mode. To explain this discrepancy, the present investigation tested the hypothesis that a metabolite of isoflurane, trifluoroacetic acid (TFA), contributes to isoflurnae-induced cardioprotection via $K_{ATP}$ channel activation during myocardial ischemia and reperfusion. Methods: Single ventricular myocytes were isolated from rabbit hearts by an enzymatic dissociation procedure. Patch-clamp techniques were used to record single-channel currents. $K_{ATP}$ channel activities were assessed before and after the application of TFA with the inside-out patch mode. Results: TFA enhanced channel activity in a concentration-dependent fashion. The concentration of TFA for half-maximal activation and the Hill coefficient were 0.03 mM and 1.2, respectively. TFA did not affect the single channel conductance of $K_{ATP}$ channels. Analysis of open and closed time distributions showed that TFA increased burst duration and decreased the interburst interval without changes in open and closed time distributions shorter than 5 ms. TFA diminished ATP sensitivity of $K_{ATP}$ channels in a concentration-response relationship for ATP. Conclusions: TFA, a metabolite of isoflurane, enhanced $K_{ATP}$ channel activity in a concentration-dependent fashion. These results imply that TFA could mediate isoflurane-induced cardioprotection via $K_{ATP}$ channel activation during myocardial ischemia and reperfusion.

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Influence of Sulfur and Fluorine Compounds on the Growth and Yield of Rice Plants;I. Growth Retardation and Yield Reduction under Various Stressed Conditions in the Field (황화물(黃化物) 및 불화물(弗化物)이 수도생육(水稻生育)과 수량(收量)에 미치는 영향(影響);I. 오염지역(汚染地域)에서의 생육장해(生育障害) 및 수량감소(收量減少))

  • Park, Wan-Cheol;Shin, Eung-Bai;Kim, Kwang-Ho
    • Korean Journal of Environmental Agriculture
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    • v.6 no.2
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    • pp.53-65
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    • 1987
  • The study was performed to investigate the effect of gaseous emissions of sulfur dioxide and hydrogen fluoride on the growth of rice plants under stressed field conditions consisting of 88 industrial plants operating with 285 smoke stacks emitting pollutants. As for the relationship between yields and yield components it is believed that the panicles per hill is the single most important component affecting the rate of yield of the rice plant. Based on the standard partial regression coefficient analysis, panicles per hill has the largest contribution to yield and the average contribution of 54%. Other components such as spikelets per panicle, percent fertility and 1000 grain weight are also contributing factors to yield, although far less so. Fluorine content in the leaf appear to have more negative effect on panicles per hill, percent fertility and subsequent overall yield than does sulfur content in the leaf. It is constantly observed and interesting to note that fluorine and sulfur content in the leaf appears to have no effect on spikelets per panicle and 1000 grain weight. Reduction in yield seems to be affected mainly by panicles per hill which are, in turn, affected more by fluorine content in the leaf as demonstrated by the standard partial coefficient analysis. Regarding the prediction sum of the square of the regression equation, the lowest value was found when nine variables were used for the analysis. The variables taken into consideration were the monthly sulfur and fluorine content in the leaf as well as the monthly percent of leaf damage during the months of June, July and August. A significant correlation is found between the actual and predicted yields by the regression equations selected as a result of a prediction sum of the square analysis.

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Integrated Structure and Controller Design of Single-Link Flexible Arm for Improving the Performance of Position Control (유연 외팔보의 위치제어 성능향상을 위한 형상 및 제어기 통합설계)

  • Lee, Min-U;Park, Jang-Hyeon
    • Journal of the Korean Society for Precision Engineering
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    • v.19 no.10
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    • pp.120-129
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    • 2002
  • An integrated structure and controller design approach for rotating cantilever beam is presented. An optimization method is developed for improving positioning performance considering the elastic deformations during high speed rotation and adopting the beam shape and the control gains as design variables. For this end, a dynamic model is setup by the finite element method according to the shape of the beam. The mass and stiffness of the beam are distributed in such a way that the closed-loop poles of the control system should be located leftmost in the complex s-plane. For optimization method, the simulated annealing method is employed which has higher probability to find the global minimum than the gradient-based down-hill methods. Sequential design and simultaneous design methods are proposed to obtain the optimal shape and controller. Simulations are performed with new designs by the two methods to verify the effectiveness of the approach and the results show that the settling time is improved for point-to-point position controls.

Temperature Prediction of Al6061 Tube in Cryogenic Heat Treatment by CFD Analysis and Experimental Verification (CFD 해석을 이용한 Al6061 튜브의 극저온 열처리 시 소재의 온도 예측 및 실험적 검증)

  • Hwang, Seong-Jun;Ko, Dae-Hoon;Kim, Dong-Hwan;Kim, Byung-Min
    • Journal of the Korean Society for Precision Engineering
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    • v.28 no.10
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    • pp.1210-1216
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    • 2011
  • The purpose of this study is to establish the analysis method for prediction of temperature during cryogenic heat treatment. Experimental cryogenic heat treatment is conducted to observe the phenomena such as boiling of fluid, ice layer on the material surface and to measure the temperature distribution of Al6061 tube. The CFD analysis considering the observed phenomena in the experiment is performed to predict the temperature distribution and convection heat transfer coefficient at each stage of cryogenic heat treatment, in which the boiling of fluid is considered as the multi-phase condition of vapour and liquid. The formation of ice layer on the tube surface is also modeled between material and fluid. The predicted results are in good agreement with the experimental ones. From the results, it is shown that the analysis method can predict the temperature distribution and convection heat transfer coefficient during cryogenic heat treatment.

Identification and Classification of the Muscarinic Receptors in the Uterus (자궁 무스카린수용체의 확인 및 분류)

  • Lee, Shin-Woong;Lee, Jeung-Soo;Park, Young-Joo
    • YAKHAK HOEJI
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    • v.36 no.3
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    • pp.220-229
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    • 1992
  • The muscarinic acetylcholine receptors of the dog unpregant uterus were characterized using $[^3H]quinuclidinyl$ benzilate(QNB) as a radioligand and the binding of muscarinic receptor agonists and antagonists in the uterus was compared to that in the urinary bladder which contains almost exclusively the M2 receptors in order to determine the receptor subtypes in the uterus. $[^3H]QNB$ binding to uterus and bladder was rapid, saturable and reversible. Scatchard analysis of the saturation data gave linear plots and the Hill coefficients were close to unit, which indicated that each preparation contained a single population of specific binding sites for $[^3H]QNB$. The KD values(120 pM) for QNB were almost identical in both organs, whereas the $B_{max}$ value of 256 fmol/mg protein in the uterus was significantly different from that of 563 fmol/mg protein in the bladder. Muscarinic agonists and antagonists inhibited in a competitive manner the $[^3H]QNB$ binding to the same extent in both organs. The competition binding studies using antagonists(atropine and pirenzepine) exhibited a single binding site and this site had a low affinity for pirenzepine with the Ki value of about 330 nM. However, high and low affinity binding sites were observed with carbachol, methacholine and oxotremorine. These binding studies with agonists and antagonists did not show any differences in drug affinities between uterus and bladder. These results indicate that the muscarinic receptors in the uterus are M2 receptors which have a low affinity for pirenzepine.

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The effect of application time of fertilizer nitrogen on its uptake rate and distribution in rice plant (질소(窒素) 시용시기별(施用時期別) 질소흡수율(窒素吸收率)과 수도체내(水稻體內)의 분포(分布)에 관한 연구(硏究))

  • Shim, Sang Chil;Kim, Tai Soon;Song, Ki Joon
    • Korean Journal of Soil Science and Fertilizer
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    • v.7 no.2
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    • pp.113-118
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    • 1974
  • A study was carried out to investigate the effect of application time of fertilizer nitrogen on its rate of uptake and its distribution in rice plant. The rate of applied fertilizer was 100kg/ha, as a single application at transplanting time and four equal split applications of 25kg/ha was applied at transplanting time, 3 weeks after transplanting, 1 week before the primodial initiation stage of growth and at the flag leaf stage of growth, respectively. The ammonium sulfate was labelled with N-15, as 1% atom excess for single application and 4.4% atom excess for split applications. The results are sumarized as follows: 1. The effect of split application of nitrogen on yield was observed. The yield of brown rice of the single application at transplanting time was 3.1 ton/ha and the split application was 3.4 ton/ha. However, without nitrogen the yield was reduced to 1.9 ton/ha. 2. The number of grains per panicle and 1000 grains weight were increased as split application of nitrogen, but for the number of panicles per hill and maturing rate, the single application of nitrogen revealed favorable results. 3. The rate of uptake of applied fertilizer nitrogen showed a tendency that the efficiency of fertilizer nitrogen increased by top dressing. The rate of uptake of applied nitrogen as basal application, first top dressing, second top dressing and third top dressing was 28%, 33% 51% and 63%, respectively. 4. After shooting stage of the growth, nitrogen in straws transfered to grains. The nitrogen applied at flag leaf stage was absorbed by root and easily accumulated in grains rather than straw.

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CLASSIFICATION OF MUSCARINIC RECEPTOR SUBTYPES BY OXOMEMAZINE

  • Lee, Shin-Woong-;Woo, Chang-Woo;Kim, Jeung-Gu-
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1994.04a
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    • pp.290-290
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    • 1994
  • The binding characteristic of oxomemazine to muscarinic receptor in the cerebrum, heart, and ileum were compared to those of pirenzepine to investigate whether oxomemazine could classify the muscarinic receptor subtypes. 〔$^3$H〕Quinucl idinyl benzilate(QNB) identified a single class of muscarinic receptors with apparent K$\sub$D/ value of about 60 pM in three tissues. Analysis of the pirenzepine inhibition curve of 〔$^3$H〕QNB binding to cerebral microsome indicated the presence of two receptor subtypes with high (Ki=16 nM, M$_1$-receptor) and low (Ki=400 nM, M$_2$-receptor) affinity for pirenzepine. Oxomemazine also identified two receptor subtypes with high (Ki=84 nM, On-receptor) and low (Ki=1 4 ${\mu}$M, O$\sub$L/-receptor) affinity in rat cerebral microsome, The percentage population of the M$_1$-and M$_2$-receptors to the total receptors were 61 : 39, and those of the O$\^$H/- and O$\sub$L/-receptors 39 : 61, respectively, However, the Hill coefficients of these two drugs for the inhibition of 〔$^3$H〕QNB binding to the heart and ileum were close to unity which indicated that these drugs bound to a uniform population of receptors in these two tissues. The Ki values for the low affinity sites of pirenzepine and oxomemazine in the cerebrum were similar to those of these drugs in the heart ileum. Both pirenzepine and oxomemazine increased K$\sub$D/ value for 〔$^3$H〕QNB without affecting the binding sites concentration and Hill coefficient for the 〔$^3$H〕QNB binding. Oxomemazine had a 10-fold lower affinity at Ma-receptors than at M$_1$-receptors, and pirenzepine a 8-fold lower affinity at O$\sub$L/-receptors than OH-receptors. Analysis of the shal low competition curves of oxomemazine for the H$_1$ receptors and pirenzepine for the O$\sub$L/-receptors yielded that 69% of the M$_1$-receptors were of the O$\sub$H/-receptors and the remaining 31% of the O$\sub$L/-receptors, and that 29% of the O$\sub$L/-receptors were of the M$_1$-receptors and 71% of the M$_2$-receptors. However, M$_2$ for oxomemazine and O$\sub$H/ for pirenzepine were composed of a uniform population. These results suggest that oxomemazine could discriminatethe muscarnic receptor subtypes and may subclassify the M$_1$-receptors into two subtypes.

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