• Journal of Chest Surgery
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• v.29 no.7
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• pp.700-712
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• 1996

Transpulmonary sequestration of leukocyte following cardiopulmonary bypass(CPB) has been recognized as one of main causes of postoperative pulmonary dysfunction. The purpose of this study is to investigate the effect of a single dose of prebypass corticosteroid on pulmonary leukostasis and postoperative pulmonary dysfunction. The study was performed prospectively in randomized-blind fas ion for 50 patients from January 1995 to June 1995. All patients were divided into two groups; In the steroid group(n=25), corticosteroid(Solu-Medrol 30mg1kg) was injected prior to CPB and in the placebo group (n=25), normal saline was injected before CPB. The results were summarized as follows. 1. Total peripheral leukocyte counts decreased significantly at 5 minutes of CPB in all patients(P<0.01), and began to increase progressively at later periods of CPB with neutrophilia. The significant rise remained at postoperative 7th day. 2. During partial CPB, transpulmonary leukostasis occurred in placebo group(P< 0.001), whereas it was prevented in steroid group. 3. In both groups, peripheral Lymphocyte counts were stable during CPB, but began to reduce at time of intensive care unit(ICV) and the Iymphocytopenia remained until postoperative )rd day. The Iympho- cyte counts recovered on postoperative 7th day. 4. In both groups, peripheral counts of monocyte were relatively stable in the e rly peroid of CPB, and increased gradually in the later periods of CPB. This significant monocytosis remained throughout postoperative periods(P< 0.05). 5. The mean value of postoperative PaOa was lower than that of pre-CPB In placebo group(P=0.01), but in steroid group, there was no significant difference(P=0. 90) and fever was higher in placebo group compared to steroid group(P=0.001).

• Journal of the Korean GEO-environmental Society
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• v.2 no.1
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• pp.31-35
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• 2001

The effects of the ratio of effective size of filter media and diatom size on filter run time were evaluated by using both reported data and experimental results from several water treatment plants. For single media at several WTPs, the range of probability of the filter run time less than 15hr was 10~60%, and for dual media, that of the filter run time less than 30hr was 10~20%. The major filter clogging algae was Synedra acus of which dominant ratio was in the range of 64~92%. The effective size(ES) of filter medium for dual media filter was 0.71~1.40mm and uniformity coefficient of the filter was 1.25~1.67. The effective size(ES) of filter medium for single medium filter was 0.52~0.65mm and uniformity coefficient of the filter was 0.25~1.40. The range of calculated penetration depth was 2.58~15.4cm for dual media and 1.29~2.17cm for single media, and average filter run time was 40.1~83.3hr and 13.9~34.9hr, respectively. When Synedra counts were over 400cells/ml for single media, filter run time was below 5hr, while filter run time for dual media filter, remained as high as 70hr.

• Food Science of Animal Resources
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• v.35 no.2
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• pp.189-196
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• 2015

The aim of this study was to manufacture functional high protein fermented beverage, using whey protein concentrate (WPC) and Lactobacillus plantarum DK211 isolated from kimchi, and to evaluate the physicochemical, functional, and sensory properties of the resulting product. The fermented whey beverage (FWB) was formulated with whey protein concentrate 80 (WPC 80), skim milk powder, and sucrose; and fermented with Lactobacillus plantarum DK211 as single, or mixed with Lactococcus lactis R704, a commercial starter culture. The pH, titratable acidity, and viable cell counts during fermentation and storage were evaluated. It was found that the mixed culture showed faster acid development than the single culture. The resulting FWB had high protein (9%) and low fat content (0.2%). Increased viscosity, and antioxidant and antimicrobial activity were observed after fermentation. A viable cell count of 10⁹ CFU/mL in FWB was achieved within 10 h fermentation, and it remained throughout storage at 15℃ for 28 d. Sensory analysis was also conducted, and compared to that of a commercial protein drink. The sensory scores of FWB were similar to those of the commercial protein drink in most attributes, except sourness. The sourness was highly related with the high lactic acid content produced during fermentation. The results showed that WPC and vegetable origin lactic acid bacteria isolated from kimchi might be used for the development of a high protein fermented beverage, with improved functionality and organoleptic properties.

• ETRI Journal
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• v.37 no.6
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• pp.1143-1153
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• 2015

In this paper, we propose an efficient architecture for a real-time image stitching engine for vision SoCs found in motor vehicles. To enlarge the obstacle-detection distance and area for safety, we adopt panoramic images from multiple telegraphic cameras. We propose a stitching method based on a fixed homography that is educed from the initial frame of a video sequence and is used to warp all input images without regeneration. Because the fixed homography is generated only once at the initial state, we can calculate it using SW to reduce HW costs. The proposed warping HW engine is based on a linear transform of the pixel positions of warped images and can reduce the computational complexity by 90% or more as compared to a conventional method. A dual-core SW/HW image stitching engine is applied to stitching input frames in parallel to improve the performance by 70% or more as compared to a single-core engine operation. In addition, a dual-core structure is used to detect a failure in state machines using rock-step logic to satisfy the ISO26262 standard. The dual-core SW/HW image stitching engine is fabricated in SoC with 254,968 gate counts using Global Foundry's 65 nm CMOS process. The single-core engine can make panoramic images from three YCbCr 4:2:0 formatted VGA images at 44 frames per second and frequency of 200 MHz without an LCD display.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.2
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• pp.386-392
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• 2015

Data in a image compression codec are processed with a specific regular block size. The processing order of block sized data is changed in specific function blocks and the data is packed in memory and read by a new sequence. To maintain a regular throughput rate, double buffering is normally used that interleaving two block sized memory to do concurrent read and write operations. Single buffering using only one block sized memory can be adopted to the simple data reordering, but when a complicate reordering occurs, irregular address changes prohibit from implementing adequate address generating for single buffering. This paper shows that there is a predictable and recurring regularity of changing address access orders within a finite updating counts and suggests an effective method to implement. The data reordering function using suggested idea is designed with HDL and implemented with TSMC 0.18 CMOS process library. In various scan blocks, it shows more than 40% size reduction compared with a conventional method.

• Mycobiology
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• v.51 no.3
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• pp.139-147
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• 2023

Aspergillus sojae has long been considered a domesticated strain of Aspergillus parasiticus. This study delineated relationships among the two species and an Aspergillus PWE36 isolate. Of 25 examined clustered aflatoxin genes of PWE36, 20 gene sequences were identical to those of A. sojae, but all had variations to those of A. parasiticus. Additionally, PWE36 developmental genes of conidiation and sclerotial formation, overall, shared higher degrees of nucleotide sequence identity with A. sojae genes than with A. parasiticus genes. Examination of defective cyclopiazonic acid gene clusters revealed that the PWE36 deletion pattern was identical only to those of A. sojae. Using A. sojae SMF134 genome sequence as a reference, visualization of locally collinear blocks indicated that PWE36 shared higher genome sequence homologies with A. sojae than with A. parasiticus. Phylogenetic inference based on genome-wide single nucleotide polymorphisms (SNPs) and total SNP counts showed that A. sojae strains formed a monophyletic clade and were clonal. Two (Argentinian and Ugandan) A. parasiticus isolates but not including an Ethiopian isolate formed a monophyletic clade, which showed that A. parasiticus population is genetically diverse and distant to A. sojae. PWE36 and A. sojae shared a most recent common ancestor (MRCA). The estimated divergence time for PWE36 and A. sojae was about 0.4 mya. Unlike Aspergillus oryzae, another koji mold that includes genetically diverse populations, the findings that current A. sojae strains formed a monophyletic group and shared the MRCA with PWE36 allow A. sojae to be continuously treated as a species for food safety reasons.

• The Journal of Korean Institute of Next Generation Computing
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• v.13 no.5
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• pp.51-70
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• 2017

The reliability of broadcasting over vehicular ad hoc networks (VANETs) is one of the most critical factors for driving safety applications. There exists limitations to improve the reliability of broadcast transmissions in saturated VANETs where previous proposals in literature tackle the problem by heuristically adapting the size of the contention window (CW). This paper considers improving the reliability by proposing a new probability model based on the counting methods of permutations and combinations, which counts all the possible cases of broadcast failures in a single-hop broadcast transmission for a given CW. From the model, we calculate the best CW size given the number of contention nodes, which significantly improves the reliability and satisfying the timely dissemination of emergency broadcasting messages. Through extensive VANET simulations with varying densities, we show that our model maintains near 100 percent success rate for single-hop broadcast as well as multi-hop broadcast (e.g. 40 hops) and achieves minimal broadcast delay.

• Clinical and Experimental Reproductive Medicine
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• v.50 no.4
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• pp.292-298
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• 2023

Objective: Ovarian torsion is a gynecological disorder that causes ischemia-reperfusion injuries in the ovary. Our study investigated berberine's short- and long-term effects on ovarian ischemia-reperfusion injuries. Methods: This study included 28 Wistar albino female rats weighing 180 to 220 g, which were divided into four groups: sham (S), torsion/detorsion (T/D), torsion/ detorsion+single dose berberine (T/D+Bb), and torsion/detorsion+15 days berberine (T/D+15Bb). The torsion and detorsion model was applied in all non-sham groups. In the T/D+Bb group, a single dose of berberine was administered, while in the T/D+15Bb group, berberine was administered over a period of 15 days. After the rats were euthanized, their ovaries were excised. The left ovaries were used for histopathologic evaluation, which included ovarian injury scoring and follicle count, while the right ovaries were used for biochemical analyses (tissue transforming growth factor-β [TGF-β] and alpha-smooth muscle actin [α-SMA] levels). Results: The histopathologic evaluation scores for the ovaries were significantly lower in the T/D+B group (p<0.05) and the T/D+15B group (p<0.005) than in the T/D group. The follicle counts in the T/D group were lower than those in both the sham and treated groups (p<0.005). The TGF-β levels were significantly lower in the T/D+15B group (p<0.005), whereas the α-SMA levels did not show a significant difference. Conclusion: Both short- and long-term berberine use could potentially have therapeutic effects on ovarian torsion. Long-term berberine use exhibited anti-inflammatory effects by reducing TGF-β levels, thereby preventing ischemia-reperfusion injuries. Therefore, we suggest that long-term berberine use could be beneficial for ovarian torsion.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2000.04a
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• pp.44-48
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• 2000

Several parameters to represent the characteristics of the observed at the domestic networks from several earthquakes occurred in the Korean Peninsula. Parameters to fit most the multiple Fourier amplitude spectra of the observed accelerations are estimated. This study adopts the stochastic ground motion model referred to the BLWN mode in which the energy is distributed randomly over the duration of the source and which has proven to be very effective in modeling a wide range of ground motion observations. The stochastic ground motion model employed here uses an omega-squared ({{{{ omega ^2 }}) Brune source model with a single corner frequency and a constant stress drop,. The {{{{ omega ^2 }} source model has become a seismological standard because of its simplicity an ability to predict spectral amplitudes and shapes over an extremely broad ranges of magnitudes distances and from the inversion show very unstable based on the fact of high values of mean/median. These results may imply that more observed data and more precise site classification including accurate preparation analysis of data such as more accurate scaling from counts to kine are needed for more stable are effective inversion of Fourier amplitude spectrum of the observed ground motions.

• Biomolecules & Therapeutics
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• v.5 no.2
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• pp.110-116
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• 1997

The present study was designed to evaluate the effects of a recombinant human granulocyte-colony stimulating factor (G-CSF) on leukopenia and tumor growth in mice treated with DA-125, an adri-amycin (ADM) derivative. In normal mice, single intravenous injection of DA-125 produced transient leukopenia accompanied with weight loss and splenic atrophy in a dose-related manner. However, subcutane-ous administration of G-CSF (5$\mu$g/head) for 5 consecutive days after DA-125 resulted in a significantly elevated nadir of leukocyte counts and facilitation of recovery from the leukopenia. To investigate the effect of G-CSF on antitumor effects of DA-125, ADM (12 mg/kg) or DA-125 (40 mg/kg) was administered to Colon-26 murine adenocarcinoma-bearing Balb/c mice with G-CSF. Regardless of treatment with G-CSF, DA-125 and ADM markedly retarded the growth of implanted tumor, though they failed to increase mean survival time of tumor-bearing mice. These results suggest that G-CSF is able to not only ameliorate, but reconstitute DA-125-induced myelosuppression without affecting its antitumor potential.