• 동의생리병리학회지
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• 제24권6호
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• pp.1094-1098
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• 2010

With the high prevalence of functional dyspepsia in the world, it was difficult to get objective diagnosis, treatment and assessment for the reason that there were many different symptoms and signs. The purpose of this study is to develop a standard instrument of pattern identification for functional dyspepsia which will be applied to clinical research. The items and structure of the instrument were based on review of published literature. The advisor committee on this study was organized by 11 oriental division of gastroenterology professors of oriental medical colleges nationwide. The experts discussed developing the instrument, and we also took professional advices by e-mail. We divided the symptoms and signs of functional dyspepsia into 6 pattern identification, such as disharmony of liver and stomach, retention of undigested food, damp-heat in the spleen and stomach, simultaneous occurrence of cold and heat syndromes, deficiency and cold of the spleen and the stomach, and insufficiency of stomach eum. We got the mean weights to each symptom of six pattern identification which had been scored on a 5-point scale ranging from 1 to 5 by the 11 experts. We made out the Korean instrument of the pattern identification composed of 45 questions for functional dyspepsia. Although there are some limitations in our study, the instrument is meaningful and certain worth of its own. We hope to improve the instrument through the further clinical studies and discussions.

• Toxicological Research
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• 제33권2호
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• pp.141-147
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• 2017

Peripheral ameloblastic odontoma is a rare variant of odontogenic tumor occurring in the extraosseous region. The present report describes a spontaneous tumor in male Sprague-Dawley (SD) rats. The clinically confirmed nodule in the right mandibular region was first observed when the rat was 42 weeks and remained until the terminal sacrifice date when the animal was 48 weeks of age. At necropsy, a well demarcated nodule, approximately $2.5{\times}2.0{\times}2.0cm$, protruded from the ventral area of the right mandible. The nodule was not attached to mandibular bone and was not continuous with the normal teeth. Histopathologically, the tumor was characterized by the simultaneous occurrence of an ameloblastomatous component and composite odontoma-like elements within the same tumor. The epithelial portion formed islands or cords resembling the follicle or plexiform pattern typical of ameloblastoma and was surrounded by mesenchymal tissue. Formation of eosinophilic and basophilic hard tissue matrix (dentin and enamel) resembling odontoma was observed in the center of the tumor. Mitotic figures were rare, and areas of cystic degeneration were present. Immunohistochemically, the epithelial component was positive for cytokeratin AE1/AE3 (CK AE1/AE3), and the mesenchymal component and odontoblast-like cells were positive for vimentin, in the same manner as in normal teeth. On the basis of these findings, the tumor was diagnosed as a peripheral ameloblastic odontoma in an extraosseous mandibular region in a SD rat. In the present study, we report the uncommon spontaneous peripheral ameloblastic odontoma in the SD rat. We also discuss here the morphological characteristics, origin, histochemical, and immunohistochemical features for the diagnosis of this tumor.

• 한국잡초학회지
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• 제18권3호
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• pp.186-190
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• 1998

맥류(麥類)의 생력화 재배법인 벼 수확동시 맥류 파종에서 효과적인 잡초방제법을 확립코자 2년간에 걸쳐 무경운(無耕耘)조건에서 잡초방제에 관한 시험을 수행한 결과는 다음과 같다. 1. Buta EC.와 Glyphosate SL을 벼 수확동시 맥류파종 당일 혼합살포한 처리에서 밀의 수수(穗數)가 손제초구와 비슷하게 확보되었다. 2. 잡초발생 및 방제가는 Buta EC + Glyphosate SL 혼합살포구에서 방임구에 비해 둑새풀과 광엽잡초 발생이 현저하게 억제되었으며 방제가도 92%로 우수하였다. 생육중기 처리제인 Thifensulfuron methyl WG도 우수한 방제가를 보였다. 3. 1년차 포장에서는 잡초발생이 단순하였으나, 무경운(無耕耘)관리가 계속된 2년차 포장에서는 발생초종이 다양화되고 둑새풀의 우점(優點)비율이 높았다. 4. 밀 수량은 Buta EC + Glyphosate SL 혼합살포구와 손제초구간에 차이가 없었다. 둑새풀 건물중과 밀수량 간에는 y = -0.21x + 627.9 ($R^2$=0.65)의 직선적인 회귀관계가 있었다.

• Animal cells and systems
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• 제8권4호
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• pp.295-300
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• 2004

In the breeding colony of black-tailed gull, as nests of conspecific neighbors are very closely located, chicks are permanently exposed by sound and visual stimuli produced by adult conspecifics approaching their nests. The chicks, therefore, may need to learn ways to appropriately respond to their parents approach. In this study we experimentally manipulated sensory stimulation that is potentially provided by the parents to the offspring. Chicks incubated in the laboratory were exposed to a mew call of the conspecific adult. Then they were tested in three situations differing in sensory stimulation: 1) visual stimulation only, 2) auditory stimulation only, and 3) Simultaneous visual and auditory stimulations. We observed occurrence of different response of the chicks, which were categorized into three behaviors (begging call response, chirirah call and pecking behavior). We also investigated intensity of the chicks call in response to the different stimulations and the degree of response with age. The chicks exposed to only auditory stimulation made significantly more chirirah calls. The intensities (dB) of the mew call and chicks chirirah call were directly correlated. On the other hand, when chicks just saw the stuffed adult gull, they responded significantly more with a begging call and pecking behavior. In the situation of costimulation, the chicks responded with a begging call and pecking, but less frequently than visual stimulation only. The results suggest that young black-tailed gulls use call repertories to properly respond to parents behavior. Such results suggest an evolutionary process for uncreasing their survival rate in a group breeding site.

• Tuberculosis and Respiratory Diseases
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• 제83권3호
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• pp.211-217
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• 2020

The gold standard method for diagnosis of tuberculosis is the isolation of Mycobacterium tuberculosis through culture, but there is a probability of cross-contamination in simultaneous cultures of samples causing false-positives. This can result in delayed treatment of the underlying disease and drug side effects. In this paper, we reviewed studies on false-positive cultures of M. tuberculosis. Rate of occurrence, effective factors, and extent of false-positives were analyzed. Ways to identify and reduce the false-positives and management of them are critical for all laboratories. In most cases, false-positive is occurring in cases with only one positive culture but negative direct smear. The three most crucial factors in this regard are inappropriate technician function, contamination of reagents, and aerosol production. Thus, to reduce false-positives, good laboratory practice, as well as use of whole-genome sequencing or genotyping of all positive culture samples with a robust, extra pure method and rapid response, are essential for minimizing the rate of false-positives. Indeed, molecular approaches and epidemiological surveillance can provide a valuable tool besides culture to identify possible false positives.

• Structural Engineering and Mechanics
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• 제25권4호
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• pp.481-500
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• 2007

The dynamic instability of doubly curved panels, subjected to non-uniform tensile in-plane harmonic edge loading $P(t)=P_s+P_d\;{\cos}{\Omega}t$ is investigated. The present work deals with the problem of the occurrence of combination resonances in contrast to simple resonances in parametrically excited doubly curved panels. Analytical expressions for the instability regions are obtained at ${\Omega}={\omega}_m+{\omega}_n$, (${\Omega}$ is the excitation frequency and ${\omega}_m$ and ${\omega}_n$ are the natural frequencies of the system) by using the method of multiple scales. It is shown that, besides the principal instability region at ${\Omega}=2{\omega}_1$, where ${\omega}_1$ is the fundamental frequency, other cases of ${\Omega}={\omega}_m+{\omega}_n$, related to other modes, can be of major importance and yield a significantly enlarged instability region. The effects of edge loading, curvature, damping and the static load factor on dynamic instability behavior of simply supported doubly curved panels are studied. The results show that under localized edge loading, combination resonance zones are as important as simple resonance zones. The effects of damping show that there is a finite critical value of the dynamic load factor for each instability region below which the curved panels cannot become dynamically unstable. This example of simultaneous excitation of two modes, each oscillating steadily at its own natural frequency, may be of considerable interest in vibration testing of actual structures.

• Journal of Microbiology and Biotechnology
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• 제22권12호
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• pp.1613-1620
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• 2012

Bacterial wilt caused by Ralstonia solanacearum is a devastating disease of many economically important crops. Since there is no promising control strategy for bacterial wilt, phage therapy could be adopted using virulent phages. We used phage PE204 as a model lytic bacteriophage to investigate its biocontrol potential for bacterial wilt on tomato plants. The phage PE204 has a short-tailed icosahedral structure and double-stranded DNA genome similar to that of the members of Podoviridae. PE204 is stable under a wide range of temperature and pH, and is also stable in the presence of the surfactant Silwet L-77. An artificial soil microcosm (ASM) to study phage stability in soil was adopted to investigate phage viability under a controlled system. Whereas phage showed less stability under elevated temperature in the ASM, the presence of host bacteria helped to maintain a stable phage population. Simultaneous treatment of phage PE204 at $10^8$ PFU/ml with R. solanacearum on tomato rhizosphere completely inhibited bacterial wilt occurrence, and amendment of Silwet L-77 at 0.1% to the phage suspension did not impair the disease control activity of PE204. The biocontrol activities of phage PE204 application onto tomato rhizosphere before or after R. solanacearum inoculation were also investigated. Whereas pretreatment with the phage was not effective in the control of bacterial wilt, post-treatment of PE204 delayed bacterial wilt development. Our results suggested that appropriate application of lytic phages to the plant root system with a surfactant such as Silwet L-77 could be used to control the bacterial wilt of crops.

• 한국임상수의학회지
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• 제31권6호
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• pp.544-546
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• 2014

식욕 부진과 복부 팽만을 보인 1.5살령의 암컷 토끼가 방사선 검사와 초음파 검사에서 자궁 확장 소견이 확인되었고, 이틀 후 쇼크로 응급 내원하여 탐색적 개복술을 실시하였다. 양측 자궁각이 자궁 경부에서 염전되어 있었고, 양측 자궁각의 내용물에 대한 배양 검사 결과 우측 자궁각은 자궁수종, 좌측 자궁각은 자궁축농증이 발생한 것으로 진단되었다. 질병의 발생 기전에 대해 정확하게 설명하기 어렵지만, 복부 팽만이 4개월간 지속되다가 갑자기 토끼 상태가 악화되어 쇼크로 진행된 점으로 미루어 초기에 자궁수종이 발생하였다가 감염 및 자궁 내 다량의 내용물로 인한 자궁염전이 급성으로 발생한 것으로 판단되었다. 본 증례는 각각의 자궁각에 자궁수종과 자궁축농증이 별도로 발생하고 염전이 동반된 매우 드문 예이다.

• Smart Structures and Systems
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• 제18권3호
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• pp.485-500
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• 2016

Stay cables in some cable-stayed bridges suffer large amplitude vibrations under the simultaneous occurrence of rain and wind. This phenomenon is called rain-wind-induced vibration (RWIV). The upper rivulet oscillating circumferentially on the inclined cable surface plays an important role in this phenomenon. However, its small size and high sensitivity to wind flow make measuring rivulet size and its movement challenging. Moreover, the distribution of the rivulet along the entire cable has not been measured. This paper applies the videogrammetric technique to measure the movement and geometry dimension of the upper rivulet along the entire cable during RWIV. A cable model is tested in an open-jet wind tunnel with artificial rain. RWIV is successfully reproduced. Only one digital video camera is employed and installed on the cable during the experiment. The camera records video clips of the upper rivulet and cable movements. The video clips are then transferred into a series of images, from which the positions of the cable and the upper rivulet at each time instant are identified by image processing. The thickness of the upper rivulet is also estimated. The oscillation amplitude, equilibrium position, and dominant frequency of the rivulet are presented. The relationship between cable and rivulet variations is also investigated. Results demonstrate that this non-contact, non-intrusive measurement method has good resolution and is cost effective.

• 한국지하수토양환경학회지:지하수토양환경
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• 제24권4호
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• pp.1-10
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• 2019

Recently, groundwater contamination by mixed occurrence of arsenic (As) and nitrate ($NO_3{^-}$) has been a serious environmental issue all around world. In this study, we investigated the microbial As(III) oxidation characteristic under denitrification process to examine the feasibility of the microbial consortia in wetland sediment to simultaneously treat these two contaminants. The detail objectives of this study were to investigate the effects of $NO_3{^-}$ on the oxidation of As(III) in anaerobic environments and observe the microbial community change during the As oxidation under denitrification process. Results showed that the As(III) was completely and simultaneously oxidized to As(V) under denitrification process, however, it occurred to a much less extent in the absence of sediment or $NO_3{^-}$. In addition, the significant increase of As(III) oxidation rate in the presence of $NO_3{^-}$ suggested the potential of As oxidation under denitrification by indigenous microorganisms in wetland sediment. Genera Pseudogulbenkiania, and Flavisolibacter were identified as predominant microbial species driving the redox process. Conclusively, this study can provide useful information on As(III) oxidation under denitrifying environment and contribute to develop an effective technology for simultaneous removal of As(III) and $NO_3{^-}$ in groundwater.