• Title/Summary/Keyword: simultaneous equation

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Method development and validation of spectrophotometric and RP-HPLC methods for simultaneous estimation of spironolactone and furosemide in bulk and combined tablet dosage forms

  • Chavan, Rohankumar R.;Bhinge, Somnath D.;Bhutkar, Mangesh A.;Randive, Dheeraj S.;Salunkhe, Vijay R.
    • Analytical Science and Technology
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    • v.34 no.5
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    • pp.212-224
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    • 2021
  • The intent of the present work was to develop a simple, sensitive, accurate, precise, rapid and economical UV- spectrophotometric and reverse phase high pressure liquid chromatographic method for the simultaneous estimation of Spironolactone and Furosemide in bulk and combined tablet dosage forms. UV-Spectrophotometry was carried out by simultaneous equation method using 0.02 M potassium dihydrogen phosphate buffer pH 3.5: Acetonitrile (50:50) v/v as a solvent. The linearity range was 2-14 ㎍ mL-1 for Spironolactone and Furosemide with a correlation coefficient > 0.99. The chromatographic separation was achieved on 250 mm × 4.6 mm, hypersil BDS C18 column with particle size 5 ㎛, by using an isocratic mixture of 0.02 M potassium dihydrogen phosphate buffer pH 3.5: Acetonitrile: tert butyl methyl ether (49:50:1) v/v/v as a solvent at a flow rate of 1 mL min-1 and UV detection was carried out at 254 nm. The retention time were observed to be 3.666 and 6.661 minutes for Furosemide and Spironolactone respectively. The two developed methods were validated according to the ICH guidelines for accuracy, precision, linearity, LOD, LOQ and were found to be within the limits. It can be concluded that these two methods could be successfully used for the simultaneous estimation of Spironolactone and Furosemide in bulk and combined tablet dosage forms.

THE STABILITY IN AN INCLINED LAYER OF VISCOELASTIC FLUID FLOW OF HYDROELECTRIC NATURAL CONVECTION

  • El-Bary, A.A.
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • v.9 no.2
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    • pp.17-27
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    • 2005
  • The problem of the onset stability in an inclined layer of dielectric viscoelastic fluid (Walter's liquid B') is studied. The analysis is made under the simultaneous action of a normal a.c. electric field and the natural convection flow due to uniformly distributed internal heat sources. The power series method used to obtain the eigen value equation which is then solved numerically to obtain the stable and unstable solutions. Numerical results are given and illustrated graphically.

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Ultimate Strength of Composite Beams with Unreinforced Web Opening (유공 합성보의 극한강도식의 제안)

  • 김창호;박종원;김희구
    • Proceedings of the Korea Concrete Institute Conference
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    • 1999.04a
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    • pp.369-374
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    • 1999
  • A practical approach of calculating the ultimate strength of composite beams with unreinforced web opening is proposed. In this method, the slab shear contribution at the opening is calculated as the smaller of the shear strength of the slab and the pullout capacity of the shear connectors at the high moment end. A simple interaction equation is used to predict the ultimate strength under simultaneous bending moment and shear force. Strength prediction by the proposed method is compared with previous test results and the predictions by other analytical method. The comparison shows that the proposed method predicts the ultimate capacity with resonable accuracy.

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HOW TO SOLVE AN INFINITE SIMULTANEOUS SYSTEM OF QUADRATIC EQUATIONS

  • Chung, Phil Ung;Lin, Ying Zhen
    • Korean Journal of Mathematics
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    • v.13 no.2
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    • pp.275-284
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    • 2005
  • In the present paper we shall introduce several operators on the reproducing kernel spaces. And using them we shall find a solution of an infinite system of quadratic equations (1.1). In particular we shall convert problem for finding an approximate solution of infinite system of quadratic equations into problem for minimizing nonnegative biquadratic polynomial.

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Analysis of Spectral Characteristics of Semiconductor Lasers under Strong Optical Injection Locking for Tens of Giga Hz Signal Generation

  • Kim, Jung-Tae
    • Journal of information and communication convergence engineering
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    • v.8 no.4
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    • pp.457-460
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    • 2010
  • we have analyzed tens of Giga pulse signal generation using sideband injection locking scheme. The numerical model for semiconductor lasers under the strong optical injection is based on the Lang's equation and has been extended in order to take into account the simultaneous injection of the multiple sidebands of the current-modulated laser. The numerical simulation results show that the unselected sidebands will affect the optical and RF-spectral characteristics even though the semiconductor laser is locked to the target sidebands.

Analyses of Short Pulse Generation Using Heterodyne Techniques

  • Kim, Jung-Tae
    • Journal of information and communication convergence engineering
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    • v.5 no.3
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    • pp.281-284
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    • 2007
  • We have analyzed the short pulse generation using heterodyne techniques. The numerical model for semiconductor lasers under the heterodyne technique is based on the Lang's equation and has been extended in order to take into account the simultaneous injection of the multiple sidebands of the current-modulated laser. The unselected sidebands will affect the optical and RF-spectral characteristics even when the semiconductor laser is locked to the target sidebands.

Characteristics of Semiconductor Laser Using Optical Injection Locking Scheme

  • Kim, Jung-Tae
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2004.05a
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    • pp.66-69
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    • 2004
  • We have investigated the spectral characteristics of semiconductor lasers locked to the external light injected from a modulated laser. The numerical model for semiconductor lasers under the external optical injection is based on the Lang's equation and has been extended in order to take into account the simultaneous injection of the multiple sidebands of the current-modulated laser. In this paper, we have analyzed characteristics of semiconductor laser using optical injection locking

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Analyses of Characteristics for Direct Intensity Modulation Scheme

  • Kim, Jung-Tae
    • Journal of information and communication convergence engineering
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    • v.4 no.3
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    • pp.101-104
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    • 2006
  • We have investigated the spectral characteristics of the semiconductor lasers locked to the sidebands of the master laser in this paper, which were expressed by a series of the Bessel function. The numerical model for the semiconductor lasers based on the typical Lang's equation has been extended in order to take into account the simultaneous injection of the multiple sidebands of the directly modulated ML. We analyses characteristics of direct intensity modulation.

Torsional Analysis of RC Beam Considering Tensile Stiffening of Concrete (콘크리트의 인장강성을 고려한 RC보의 비틀림 해석)

  • 박창규
    • Proceedings of the Korea Concrete Institute Conference
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    • 2002.10a
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    • pp.167-172
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    • 2002
  • Nonlinear analysis of the reinforced concrete beam subjected to torsion is presented. Seventeen equations involving seventeen variables are derived from the equilibrium equation, compatibility equation, and the material constitutive laws to solve the torsion problem. Newton method was used to solve the nonlinear simultaneous equations and efficient algorithms are proposed. Present model covers the behavior of reinforced concrete beam under pure torsion from service load range to ultimate stage. Tensile resistance of concrete after cracking is appropriately considered. The softened concrete truss model and the average stress-strain relations of concrete and steel are used. To verify the validity of Present model, the nominal torsional moment strengths according to ACI-99 code and the ultimate torsional moment by present model are compared to experimental torsional strengths of 55 test specimens found in literature. The ultimate torsional moment strengths by the present model show good results.

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Investigation on Numerical Integration for Radiation Heat Transfer in Radiating Fluid (복사유체의 복사열전달 수치 적분에 관한 연구)

  • Han Cho Young
    • Journal of computational fluids engineering
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    • v.9 no.2
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    • pp.43-51
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    • 2004
  • Interaction between fluid flow and thermal radiation has received considerable attention due to its numerous applications in engineering field. In this case the thermofluid properties of radiating fluid vary with the variation of temperature field caused by absorption and emission of radiant heat. To analyze the radiation heat transfer in radiating fluid, the simultaneous solution of the radiative transfer equation (RTE) and the fluid dynamics equations is required. This means that the numerical procedure used for the RTE must be computationally efficient to permit its inclusion in the other submodels, and must be compatible with the other transport equations. The finite volume method (FVM) and the discrete ordinates method (DOM) are usually employed to simulate radiation problems in generalized coordinates. These two representative methods are examined and compared, especially in view of the numerical integration of the radiation intensity over solid angle. The FVM shows better accuracy than the DOM owing to less constraints of the selection of control angle.