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Risk of Hemorrhage Attributed to Underlying Chronic Diseases and Uninterrupted Aspirin Therapy of Patients Undergoing Minor Oral Surgical Procedures: A Retrospective Cohort Study

  • Rojanaworarit, Chanapong;Limsawan, Soontaree
    • Journal of Preventive Medicine and Public Health
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    • v.50 no.3
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    • pp.165-176
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    • 2017
  • Objectives: This study aimed to estimate the risk of bleeding following minor oral surgical procedures and uninterrupted aspirin therapy in high-risk patients or patients with existing chronic diseases compared to patients who did not use aspirin during minor oral surgery at a public hospital. Methods: This retrospective cohort study analyzed the data of 2912 patients, aged 20 years or older, who underwent 5251 minor oral surgical procedures at a district hospital in Thailand. The aspirin group was comprised of patients continuing aspirin therapy during oral surgery. The non-aspirin group (reference) included all those who did not use aspirin during surgery. Immediate and late-onset bleeding was evaluated in each procedure. The risk ratio of bleeding was estimated using a multilevel Poisson regression. Results: The overall cumulative incidence of immediate bleeding was 1.3% of total procedures. No late-onset bleeding was found. A significantly greater incidence of bleeding was found in the aspirin group (5.8% of procedures, p<0.001). After adjusting for covariates, a multilevel Poisson regression model estimated that the bleeding risk in the aspirin group was 4.5 times higher than that of the non-aspirin group (95% confidence interval, 2.0 to 10.0; p<0.001). However, all bleeding events were controlled by simple hemostatic measures. Conclusions: High-risk patients or patients with existing chronic diseases who continued aspirin therapy following minor oral surgery were at a higher risk of hemorrhage than general patients who had not used aspirin. Nonetheless, bleeding complications were not life-threatening and could be promptly managed by simple hemostatic measures. The procedures could therefore be provided with an awareness of increased bleeding risk, prepared hemostatic measures, and postoperative monitoring, without the need for discontinuing aspirin, which could lead to more serious complications.

Does Early Drain Removal Affect Postoperative Pericardial Effusion after Congenital Cardiac Surgery?

  • Kim, Young Eun;Jung, Hanna;Cho, Joon Yong;Kim, Yeo Hyang;Hyun, Myung Chul;Lee, Youngok
    • Journal of Chest Surgery
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    • v.53 no.1
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    • pp.16-21
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    • 2020
  • Background: Patients undergoing cardiac surgery require postoperative chest drainage. However, the drain is difficult to keep in place in children with congenital heart disease. Since 2015, at Kyungpook National University Hospital, the chest tube is removed on postoperative day 1 in patients who have undergone simple congenital cardiac surgery (i.e., closure of an atrial or ventricular septal defect). In this study, we evaluated the relationship between the duration of drain placement and the likelihood of pericardial effusion after congenital cardiac surgery. Methods: The medical records of patients who underwent closure of an atrial or ventricular septal defect at our hospital between January 2014 and December 2016 were reviewed. In total, 162 patients who received follow-up echocardiography and had information available on postoperative pericardial effusion after the repair procedure were enrolled. Results: Echocardiography was performed at a median of 5 days (range, 4 to 6 days) postoperatively before discharge from the hospital. Pericardial effusion occurred in 21 patients (13.0%), of whom only 3 (1.9%) had moderate or greater pericardial effusion, regardless of the drain duration. All patients improved during outpatient follow-up without invasive management. No patient had severe complications because of pericardial effusion. The duration of drain placement did not affect the incidence of postoperative pericardial effusion (p=0.069). Operative survival was 100%. Conclusion: Based on our study, we recommend removing the drain as soon as its role is complete, generally on postoperative day 1, because early removal does not increase the incidence of pericardial effusion in patients undergoing simple congenital cardiac surgery.

Rapid and simple method for DNA extraction from plant and algal species suitable for PCR amplification using a chelating resin Chelex 100

  • HwangBo, Kwon;Son, Su-Hyun;Lee, Jong-Suk;Min, Sung-Ran;Ko, Suk-Min;Liu, Jang-R.;Choi, Dong-Su;Jeong, Won-Joong
    • Plant Biotechnology Reports
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    • v.4 no.1
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    • pp.49-52
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    • 2010
  • A DNA extraction method using Chelex 100 is widely used for bacteria, Chlamydomonas, and animal cell lines, but only rarely for plant materials due to the need for additional time-consuming and tedious steps. We have modified the Chelex 100 protocol and successfully developed a rapid and simple method of DNA extraction for efficient PCR-based detection of transgenes from a variety of transgenic plant and algal species. Our protocol consists of homogenizing plant tissue with a pestle, boiling the homogenized tissue in a microfuge tube with 5% Chelex 100 for 5 min, and centrifuging the boiled mixture. The supernatant, which is used for PCR analysis, was able to successfully amplify transgenes in transgenic tobacco, tomato, potato, Arabidopsis, rice, strawberry, Spirodela polyrhiza, Chlamydomonas, and Porphyra tenera. The entire DNA extraction procedure requires <15 min and is therefore comparable to that used for bacteria, Chlamydomonas, and animal cell lines.

Influence of end fixity on post-yield behaviors of a tubular member

  • Cho, Kyu Nam
    • Structural Engineering and Mechanics
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    • v.13 no.5
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    • pp.557-568
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    • 2002
  • For the evaluation of the capability of a tubular member of an offshore structure to absorb the collision energy, a simple method can be employed for the collision analysis without performing the detailed analysis. The most common simple method is the rigid-plastic method. However, in this method any characteristics for horizontal movement and rotation at the ends of the corresponding tubular member are not included. In a real structural system of an offshore structure, tubular members sustain a certain degree of elastic support from the adjacent structure. End fixity has influences in the behaviors of a tubular member. Three-dimensional FEM analysis can include the effect of end fixity fully, however in viewpoints of the inherent computational complexities of the 3-D approach, this is not the recommendable analysis at the initial design stage. In this paper, influence of end fixity on the behaviors of a tubular member is investigated, through a new approach and other approaches. A new analysis approach that includes the flexibility of the boundary points of the member is developed here. The flexibility at the ends of a tubular element is extracted using the rational reduction of the modeling characteristics. The property reduction is based on the static condensation of the related global stiffness matrix of a model to end nodal points of the tubular element. The load-displacement relation at the collision point of the tubular member with and without the end flexibility is obtained and compared. The new method lies between the rigid-plastic method and the 3-demensional analysis. It is self-evident that the rigid-plastic method gives high strengthening membrane effect of the member during global deformation, resulting in a steeper slope than the present method. On the while, full 3-D analysis gives less strengthening membrane effect on the member, resulting in a slow going load-displacement curve. Comparison of the load-displacement curves by the new approach with those by conventional methods gives the figures of the influence of end fixity on post-yielding behaviors of the relevant tubular member. One of the main contributions of this investigation is the development of an analytical rational procedure to figure out the post-yielding behaviors of a tubular member in offshore structures.

Recognition of Native Local Foods in the Jeonju Area of Korea by Adults (전주 지역 성인의 향토 음식에 대한 인식)

  • Kim, In-Sook;Choi, Ok-Beom;Yu, Hyeon-Hee;Shin, Mee-Kyung
    • Journal of the East Asian Society of Dietary Life
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    • v.17 no.6
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    • pp.765-779
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    • 2007
  • The objective of this study was to examine Jeonju residents' recognition towards their native local foods. The results indicate that their degree of interest in the native foods was above average. As age and education increased, the degree of interest was also increased. Also, married people showed greater interest as compared to single people (p<$0.05{\sim}0.001$). There were more people who said they preferred native foods than people who said they didn't, where 213 people (41.3%) answered that they preferred the native foods. Of the people who said they like native foods, their main reason was because the native foods taste good. The main reason for the people who said they disliked native foods was that they didn't have many opportunities to try native foods. TV and radio were the first means, among others, from which people learned about native foods. The place where people ate native foods most often was native food restaurants (242 people, 46.95%). A frequency of a native food intake (including home and dining-out) of $1{\sim}2$ times/year was most prominent, with 137 people (26.6%). Also, a cooking frequency of "hardly ever cooks" was most prominent with 163 people (31.6%). The most prominent reason for the low cooking frequency at home was because they didn't know the recipes. Among 5 basic recipe characteristics for native foods (easy preparation of ingredients, simple recipe procedures, quick preparation, reasonable recipe procedures, sanitation), "sanitation" had the highest average score of 3.54, and "simple recipe procedure" had the lowest score of 2.44. To summarize, in order to develop Jeonju native local foods, it is necessary to implement various strategies such as frequently holding events where people can experience their native foods, running a native food training center, advertising through TV and radio, developing easy home recipes, and simplifying recipes.

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A technique for fabricating abutment replica with hot melt adhesive material to minimize residual cement in implant restoration: a case report (임플란트 보철 합착 시 잔여 시멘트 최소화를 위해 열가소성 접착제를 이용한 복제 지대주 제작 방법: 증례보고)

  • Seo, Chi-Won;Han, A-Reum;Seo, Jae-Min;Lee, Jung-Jin
    • Journal of Dental Rehabilitation and Applied Science
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    • v.32 no.3
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    • pp.240-245
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    • 2016
  • Removal of excess cement is important to prevent biological complication in cementation of implant restoration with subgingival margin. It can be difficult to completely remove excess cement. Several techniques have been introduced to minimize excess cement using abutment replica. In this case report, a simple method for making abutment replica with hot melt adhesive material in dental office was described. This technique is simple and effective because it can be used for pre-fabricated or custom abutment without additional laboratory procedure. In addition, it can minimize excess cement after cementation of implant restoration.

Development of triangular flat-shell element using a new thin-thick plate bending element based on semiLoof constrains

  • Chen, Yong-Liang;Cen, Song;Yao, Zhen-Han;Long, Yu-Qiu;Long, Zhi-Fei
    • Structural Engineering and Mechanics
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    • v.15 no.1
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    • pp.83-114
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    • 2003
  • A new simple 3-node triangular flat-shell element with standard nodal DOF (6 DOF per node) is proposed for the linear and geometrically nonlinear analysis of very thin to thick plate and shell structures. The formulation of element GT9 (Long and Xu 1994), a generalized conforming membrane element with rigid rotational freedoms, is employed as the membrane component of the new shell element. Both one-point reduced integration scheme and a corresponding stabilization matrix are adopted for avoiding membrane locking and hourglass phenomenon. The bending component of the new element comes from a new generalized conforming Kirchhoff-Mindlin plate element TSL-T9, which is derived in this paper based on semiLoof constrains and rational shear interpolation. Thus the convergence can be guaranteed and no shear locking will happen. Furthermore, a simple hybrid procedure is suggested to improve the stress solutions, and the Updated Lagrangian formulae are also established for the geometrically nonlinear problems. Numerical results with solutions, which are solved by some other recent element models and the models in the commercial finite element software ABAQUS, are presented. They show that the proposed element, denoted as GMST18, exhibits excellent and better performance for the analysis of thin-think plates and shells in both linear and geometrically nonlinear problems.

Importance of a rigorous evaluation of the cracking moment in RC beams and slabs

  • Lopes, A.V.;Lopes, S.M.R.
    • Computers and Concrete
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    • v.9 no.4
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    • pp.275-291
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    • 2012
  • The service loads are often decisive in the design of concrete structures. The evaluation of the cracking moment, $M_{cr}$, is an important issue to predict the performance of the structure, such as, the deflections of the reinforced concrete beams and slabs. To neglect the steel bars of the section is a simplification that is normally used in the computation of the cracking moment. Such simplification leads to small errors in the value of this moment (typically less than 20%). However, these small errors can conduce to significant errors when the values of deflections need to be computed from $M_{cr}$. The article shows that an error of 10% on the evaluation of $M_{cr}$ can lead to errors over 100% in the deformation values. When the deformation of the structure is the decisive design parameter, the exact computing of the cracking moment is obviously very important. Such rigorous computing might lead to important savings in the cost of the structure. With this article the authors wish to draw the attention of the technical community to this fact. A simple equation to evaluate the cracking moment, $M_{cr}$, is proposed for a rectangular cross-section. This equation leads to cracking moments higher than those obtained by neglecting the reinforcement bars and is a simple rule that can be included in Eurocode 2. To verify the accuracy of the developed model, the results of the proposed equation was compared with a rigorous computational procedure. The proposed equation corresponds to a good agreement when compared with the previous approach and, therefore, this model can be used as a practical aid for calculating an accurate value of the cracking moment.

Bending behaviour of FGM plates via a simple quasi-3D and 2D shear deformation theories

  • Youcef, Ali;Bourada, Mohamed;Draiche, Kada;Boucham, Belhadj;Bourada, Fouad;Addou, Farouk Yahia
    • Coupled systems mechanics
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    • v.9 no.3
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    • pp.237-264
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    • 2020
  • This article investigates the static behaviour of functionally graded (FG) plates sometimes declared as advanced composite plates by using a simple and accurate quasi-3D and 2D hyperbolic higher-order shear deformation theories. The properties of functionally graded materials (FGMs) are assumed to vary continuously through the thickness direction according to exponential law distribution (E-FGM). The kinematics of the present theories is modeled with an undetermined integral component and satisfies the free transverse shear stress conditions on the top and bottom surfaces of the plate; therefore, it does not require the shear correction factor. The fundamental governing differential equations and boundary conditions of exponentially graded plates are derived by employing the static version of principle of virtual work. Analytical solutions for bending of EG plates subjected to sinusoidal distributed load are obtained for simply supported boundary conditions using Navier'is solution procedure developed in the double Fourier trigonometric series. The results for the displacements and stresses of geometrically different EG plates are presented and compared with 3D exact solution and with other quasi-3D and 2D higher-order shear deformation theories to verify the accuracy of the present theory.

Linear-Shaped Gastroduodenostomy in Totally Laparoscopic Distal Gastrectomy

  • Son, Hyaung-Mi;Lee, Sang-Lim;Hur, Hoon;Cho, Yong-Kwan;Han, Sang-Uk
    • Journal of Gastric Cancer
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    • v.10 no.2
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    • pp.69-74
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    • 2010
  • Purpose: Laparoscopic gastrectomy has been common treatment modality for gastric cancer. But, most surgeons tend to perform laparoscopy-assisted distal gastrectomy using epigastric incision. Delta-shaped anastomosis is known as intracorporeal gastroduodenostomy, but it is technically difficult and needed many staplers. So we tried to find simple and economical method, here we report on the results of liner-shaped gastroduodenostomy in totally laparoscopic distal gastrectomy. Materials and Methods: We retrospectively reviewed the medical records of 25 patients who underwent totally laparoscopic distal gastrectomy using liner-shaped anastomosis at School of Medicine, Ajou University between January to October 2009. The indication was early gastric cancer as diagnosed by preoperative workup, the anastomoses were performed by using laparoscopic linear stapler. Results: There were 12 female and 13 male patients with a mean age of $55.6{\pm}11.2$. The following procedures were performed 14 laparoscopic gastrectomies, 11 robotic gastrectomies. The mean operation time was $179.5{\pm}27.4$ minutes, the mean anastomotic time was $17.5{\pm}3.4$ minutes. The mean number of stapler cartridges was $5.6{\pm}0.8$. Postoperative complication occurred in one patient, anastomotic stenosis, and the patient required reoperation to gastrojejunostomy. The mean length of postoperative hospital stay was $6.7{\pm}1.0$ days except the complication case, and there was no case of conversion to open procedure and postoperative mortality. Conclusions: Linear-shaped gastroduodenostomy in totally laparoscopic distal gastrectomy is technically simple and feasible method.