• YAKHAK HOEJI
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• v.60 no.1
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• pp.15-20
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• 2016

Globotriaosylsphingosine (lyso Gb3) is considered as one of the biomarkers for Fabry disease. A rapid and simple UPLC-MS/MS method was developed for the determination of reliable biomarker, lyso Gb3. Total analytical procedure takes only 15 min including sample preparation and MS/MS analysis. Limit of detection was 0.85 ng/ml (S/N=3). The calibration curve was linear over the range of 2.0~400.0 ng/ml ($R^2=0.9999$). Inter-day and intra-day assay accuracy were 93.4~100.6% (RSD, 0.6~6.0%) and 97.5~100.7% (RSD, 3.6~5.2%). Absolute recoveries of 97.6~98.6 showed excellence of a new analytical method. The method was applied to human and mice urines, proved the suitability for the quantification of lyso-Gb3 for screening, diagnosis and therapeutic monitoring of Fabry disease patients.

• Proceedings of the KSR Conference
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• 2002.10b
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• pp.1074-1079
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• 2002

Long term measurement data on the bridge response caused by moving loads are fundamental ingredient to the development or improvement of the new bridge design. In addition, proper establishment of the systematic analysis and diagnosis together with the maintenance system become the essential procedure to the effective repair/reinforcement/retrofit of not only the high speed but also the conventional railway bridges. Therefore, the real time health monitoring system on the important railway bridges should be enhancing the proper maintenance of the structures. The main objective of this study is, therefore, to develop a monitoring device including Weigh-In-Motion (WIM) function and the emphasis is place on the easy and economic installation of the developed system in the field condition.

• ETRI Journal
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• v.24 no.2
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• pp.117-130
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• 2002

Due to its salient features, the optical burst switch is becoming a key technology for the optical Internet. Within this technology, the survivability issue in the optical Internet has to be addressed because a simple failure causes severe damage to the huge amount of data carried in optical fiber. In this paper, we introduce a restoration procedure that can provide good survivability in the optical burst switch (OBS)-based optical Internet. OBS restoration can survive various types of network failure while maintaining good network performance. We propose novel restoration mechanisms, namely, "temporary Label Switched Path (LSP)" and "bossy LSP," to enhance restoration time and network utilization. The simulation results verify that the proposed OBS restoration achieves good network performance and provides good network connectivity as well.

• Honam Mathematical Journal
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• v.31 no.4
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• pp.541-558
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• 2009

Anecdotes can produce an emotional and simple response that decreases stress and anxiety in a classroom. The use of anecdotes in building concepts of statistics can support an effective way of teaching and learning statistics. Particularly, we demonstrate several anecdotes including pictures as the medium of image that are designed to motivate statistical ideas by placing them at the beginning of a lecture and by appealing to prospective teachers weighed down. Our purpose is that under the constructivist view, prospective teachers have an opportunity effectively to teach statistical concepts using humorous anecdotes and to experience significant beliefs on identifying some frequent misconceptions in statistics. At this procedure, the anecdotal teaching practice is concerned with describing and evaluating many humorous anecdotes we have found useful in teaching introductory statistics. We hope that this paper can be helpful to prospective teachers who will teach students such topics as descriptive statistics, sampling, and hypothesis testing.

• Journal of Institute of Control, Robotics and Systems
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• v.22 no.6
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• pp.477-482
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• 2016

This paper presents a simple approximation-based design approach for consensus tracking of heterogeneous second-order nonlinear systems under a directed network. All nonlinearities of followers are assumed to be unknown and non-identical. In the controller design procedure, graph-independent error surfaces are used and an unimplementable intermediate controller for each follower is designed at the first design step. Then, by adding and subtracting a graph-based term at the second step, the actual controller for each follower is designed by using one neural network employed to estimate a lumped and distributed nonlinearity. Therefore, the proposed local controller for each follower has a simpler structure than existing approximation-based consensus tracking controllers for multi-agent systems with unmatched nonlinearities.

• Journal of the Earthquake Engineering Society of Korea
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• v.20 no.1
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• pp.55-62
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• 2016

It is important to select an accurate set of ground motions when conducting linear and nonlinear response history analyses of structures. This study proposes a method for selecting ground motions from a ground motion library with response spectra that match the target response spectrum mean, variance and correlation structures. This study also has addressed the determination of an appropriate value for the weight factor of a correlation structure. The proposed method is conceptually simple and straightforward, and does not involve a simulation algorithm. In this method, a desired number of ground motions are sequentially selected from first to last. The proposed method can be also used for selecting ground motions with response spectra that match the conditional spectrum. The accuracy and efficiency of the proposed procedure are verified with numerical examples.

• JSTS:Journal of Semiconductor Technology and Science
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• v.2 no.1
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• pp.87-92
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• 2002

We present a simple experimental method for determination of limiting intrinsic fixed-pattern non-uniformity (NU) due to fabrication process in two-dimensional CCD multiplexers (MUXs) that are used for hybrid focal plane arrays. Here, this is done by determining separately the two NUs viz. that are $V_T$ dependent and $V_T$ independent. From these measurements, process dependent NU can be extracted. It is argued that $V_T$ dependent NU can be eliminated by designing novel input circuits whereas $V_T$ independent NU, primarily, dependent on process control and material variations may be reduced but cannot be eliminated completely and hence limits the FPA performance eventually.

• Journal of the Korean Institute of Telematics and Electronics
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• v.19 no.4
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• pp.6-14
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• 1982

Both the power increasing of a television broadcasting channel for the purpose of minimiaing weak signal areas and depressing of radiation pattern to prevent some interference in known quadrants may be needed in TV broadcasting. This study shows that, the two needs mentioned above are solvable by adjusting the phases of feeding points, or redesigning the lengths of feeder lines between transmitter outend and feeder inputs in super gain antenna. A theoretical study on lengths of coaxial cables and a practical procedure of designing cable lengths, which is simple and inexpensive to apply, is presented.

• Bulletin of the Korean Chemical Society
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• v.25 no.8
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• pp.1143-1146
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• 2004

A simple and effective procedure for conversion of primary, secondary, allylic and benzylic alcohols into the corresponding iodides is described using $CeCl_3{\cdot}7H_2O/NaI\;over\;SiO_2$ under microwave irradiation. Benzylic alcohols are selectively converted in the presence of saturated alcohols into their corresponding benzylic iodides under these conditions.

• Bulletin of the Korean Chemical Society
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• v.32 no.3
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• pp.787-792
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• 2011

Under mild conditions and without any additional organic solvent, synthesis of carbamatoalkyl naphthols could be carried out in the present of two halogen-free Br${\phi}$nsted acidic ionic liquids, 3-methyl-1-(4-sulfonic acid)butylimidazolium hydrogen sulfate and N-(4-sulfonic acid)butylpyridinium hydrogen sulfate. A wide range of aromatic aldehydes easily undergo condensation with $\beta$-naphthol and methyl or benzyl carbamate to afford the desired products of good purity in excellent yields. The present methodology offers several advantages such as a simple procedure with an easy work-up, short reaction times, and excellent yields. The catalysts could be recycled and reused for several times without substantial reduction in their catalytic activities.