• Title/Summary/Keyword: signal sequence

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Molecular Cloning of Chicken Major Histocompatibility Complex Class II Molecules

  • Sung, Aree-Moon
    • Toxicological Research
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    • v.8 no.2
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    • pp.331-342
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    • 1992
  • The chicken major histocompatibility complex (MHC), the B complex, is beginning to be analyzed at the DNA level. Inbred lines of chickens have been reported to possess 3~5 MHC class II genes. To further analyzed the molecular structure of the chicken MHC class II genes, cDNA clones coding for chicken MHC class II (B-L) ${\beta}$ chain molecules were isolated from chicken spleen and liver. Tissue-specific transcription of B-L ${\beta}$genes was studied by Northern blot analysis. A high level of expression was detected for spleen poly(A)$^+$ RNA whereas a faint signal was detected for liver poly(A)$^+$ RNA. Twenty-nine cDNA clones were isolated from the spleen and eight cDNA clones were isolated from the liver. Based on restriction maps, most clones could be clustered into one family of genes. Four cDNA clones were sequenced (S7, S10 and S19 from the spleen and L1, which was identical to S19, from the liver). Complete amino acid sequences of B-L ${\beta}$ chain molecules were predicated from the nucleotide sequences of the cDNA clones. Although both the nature and the location of the conserved residues were similar in chicken and mammalian sequences, some species-specific differences were found, suggesting that the structures of the B-L molecules are similar, but not identical to their mammalian counterparts.

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Study of 3 dimensional wide area continuous laser micro patterning (3차원 대면적 연속 마이크로 레이저 패터닝을 위한 연구)

  • Kim, Kyunghan;Sohn, Hyonkee;Lee, Jaehoon
    • Laser Solutions
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    • v.18 no.4
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    • pp.1-5
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    • 2015
  • For continuous laser micro patterning on three-dimensional free form surface, innovative laser system is developed. The two axis galvanometer is combined with the dynamic focusing unit to increase optical distance. Also, it is synchronized with the 3 axis mechanical system. To determine laser machining sequence, laser CAM system is developed. It can make possible of 3D surface micro patterning under $25{\mu}m$ pattern width. The uniformity of pattern width is about 2.8% and it is validated that focal plane is well conserved by the dynamic focusing unit. Velocity and positional information of 1 axis is stage is fed to the scanner control board by the encoder signal and it makes possible real time synchronization. With this system, possible patterning volume is enlarged from $40{\times}40mm^2$ to $40{\times}120{\times}30mm^3$.

Ectopic Overexpression of Coiled-Coil Domain Containing 110 Delays G2/M Entry in U2-OS Cells

  • Lee, Sue Nyoung;Hong, Kyeong-Man;Seong, Yeon Sun;Kwak, Sahng-June
    • Development and Reproduction
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    • v.24 no.2
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    • pp.101-111
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    • 2020
  • Coiled-coil domain containing 110 (CCDC110, KM-HN-1) is a protein containing C-terminal coiled-coil domain (CCD) which was previously discovered as a member of the human cancer/testis antigen (CTA). In addition, CCDC110 has both nuclear localization signal sequence and the leucine zipper motif. Although the functional role of CCDC110 has yet to be fully identified, the mRNA expression levels of CCDC110 are known to be highly elevated in various cancer types including testis, implying its relevance to cancer pathogenesis. In this study, we first developed several monoclonal antibody (mAb) hybridoma clones targeting CCDC110 and further isolated clone by characterizing for its specificity using immunoblotting and immunoprecipitation approaches with basal parenchymal sperm cells in testis tissue. Next, using these mAbs, we showed that the Tet-inducible overexpression of CCDC110 protein delayed the entry of G2/M phase in U2-OS osteosarcoma cells. Based on these results, we propose that CCDC110 plays a crucial role in cell cycle progression.

The multi-use interfernce cancellation of synchronous DS/CDMA system using SIMPLEX coed and PN code (SIMPLEX 부호와 PN 부호를 사용한 동기 DS/CDMA 시스템의 다원접속간섭제거)

  • 김남선
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.23 no.4
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    • pp.967-975
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    • 1998
  • This paper presents a system to cancel the multi-user interference of synchronous DS/CDMA systems by using the estimation circuit and the reference correlator. In the code-division multiple access(CDMA) scheme, the spectrum of the user's signal is directly spreaded by means of the Simplex coed or the phase offsetted PN code. It is interesting for the Simplex code and the PN code to have a similar correalation property. It these codes are used in DS/CDMA systems, the number of acceptable users can be increased in comparison with conventioal DS/CDMA systems. This thesis presents a interference cancellation model to cancel the multi-use interference in DS/CDMA systems by using Simples code of PN code as a spreading sequence. In AWGN environment, we analyze interference generated from other users and compare the resulting performance with that of the conventioanl receiver in same user side.

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UWB Communication and Ranging System using Frequency Slope Modulated Chirp (주파수 효율 및 성능 향상을 위한 Frequency Slope Modulated Chirp 신호를 이용한 UWB 시스템)

  • Kim, Jung-Hyun;Kim, Ji-Hyun;You, Cheol-woo
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.2A
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    • pp.127-132
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    • 2011
  • This paper proposes a ranging and communicating system that uses the UWB frequency slope modulated chirp signal. Instead of using only the up-chirp and down-chirp with the same frequency sweeping rate, the proposed system uses several chirps that have different frequency sweeping rates with frequency hopping. This system performs better than the conventional communication and ranging schemes because it is capable of increasing the data transmission rate and at the same time decreasing the interference between sequences used by users. In this paper, we propose simulations of UWB communication system to show validity by using the MATLAB.

IMPROVING THE SPEECH INTELLIGIBILITY IN AN AIR-TRFFIC CONTROL ROOM

  • Pavuza, Franz G.;Beszedics, Geza W.;Pichler, Heinrich
    • Proceedings of the Acoustical Society of Korea Conference
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    • 1994.06a
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    • pp.912-918
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    • 1994
  • Poor speech intelligibility in an air traffic control room is frequently a result of many, quite different causes and occasionally leads to complaints of the controller personnel. The paper describes a sequence of successful tasks performed in a local control room. The initial measurements included an investigation of the background noise (caused by fans, air condition, computer and radar equipment) and performance checks of the electronic audio and communication equipment with respect to the audio transmission behavior. The spectral composition of the noise as well as the characteristics of the audio communication path between the controllers and the pilots(which showed a loss of spectral information in the audio band due to built-in notch filters for the suppression of control tones) required adaptations of the amplitude behavior of the amplifiers through user adjustable tone controls. The radar console fans, which contributed significantly to the overall noise floor of the room, underwent a substantial reconstruction by replacing the tight mounting with an elastic double suspension, reducing the noise level by 50%. Finally, a possible source of untimely fatigue of the controllers during their working hours has been found in strong spectral components of the noise above the audio band, radiated by numerous video monitors in the control through vibrating components excited by the line frequency of the video signal.

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북한산 국립공원의 식물상

  • 이영노
    • Proceedings of the Botanical Society of Korea Conference
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    • 1985.08b
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    • pp.19-22
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    • 1985
  • Magnaporthe grisea (Hebert) Barr (anamorph: Pyricularia grisea) is a typical heterothallic Ascomycete and the causal agent of rice blast, one of the most destructive diseases on rice (Oryza sativa L.) worldwide. The interactions between cells of the pathogen and those of the host involve a complex of biological influences which can lead to blast disease. The early stages of infection process in particular may be viewed as a sequence of discrete and critical events. These include conidial attachment, gemination, and the formation of an appressorium, a dome-shaped and melanized infection structure. Disruption of this process at any point will result in failure of the pathogen to colonize host tissues. This may offer a new avenue for developing innovative crop protection strategies. To recognize and capture such opportunities, understanding the very bases of the pathogenesis at the cellular and molecular level is prerequisite. Much has been learned about environmental cues and endogenous signaling systems for the early infection-related morphogenesis in M. grisea during last several years. The study of signal transduction system in phytopathogenic filamentous fungi offers distinct advantages over traditional mammalian systems. Mammalian systems often contain multiple copies of important genes active in the same tissue under the same physiological processes. Functional redundancy, alternate gene splicing, and specilized isoforms make defining the role of any single gene difficult. Fungi and animals are closely related kingdoms [3], so inferences between these organisms are often justified. For many genes, fungi frequently possess only a single copy, thus phenotype can be attributed directly to the mutation or deletion of any particular gene of interest.

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A Neutral-Point Voltage Balance Controller for the Equivalent SVPWM Strategy of NPC Three-Level Inverters

  • Lyu, Jianguo;Hu, Wenbin;Wu, Fuyun;Yao, Kai;Wu, Junji
    • Journal of Power Electronics
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    • v.16 no.6
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    • pp.2109-2118
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    • 2016
  • Based on the space vector pulse width modulation (SVPWM) theory, this paper realizes an easier SVPWM strategy, which is equivalently implemented by CBSPWM with zero-sequence voltage injection. The traditional SVPWM strategy has no effect on controlling the neutral-point voltage balance. In order to solve the neutral-point voltage unbalance problem for neutral-point-clamped (NPC) three-level inverters, this paper proposes a neutral-point voltage balance controller. The proposed controller realizes controlling the neutral-point voltage balance by dynamically calculating the offset superimposed to the three-phase modulation waves of an equivalent SVPWM strategy. Compared with the traditional SVPWM strategy, the proposed neutral-point voltage balance controller has a strong ability to balance the neutral-point voltage, has good steady-state performance, improves the output waveforms quality and is easy for digital implementation. An experiment has been carried out on a NPC three-level inverter prototype based on a digital signal processor-complex programmable logic device (DSP-CPLD). The obtained experimental results verify the effectiveness of the proposed neutral-point voltage balance controller.

Performance improvement of the DS-CDMA/DPSK cellular mobile communication system with CCI canceller and RAKE receiver (DS-CDMA/DPSK 셀룰라 이동통신 시스템에서 간섭 제거기와 RAKE 수신기에 의한 성능 개선)

  • 이경준;오창헌;조성준;채수환
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.33A no.4
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    • pp.37-46
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    • 1996
  • In this paper, we analyzed the performance improvement of the DS-CDMA/dPSK cellular mobile communication system with CCI canceller and RAKE receiver techniques in mobile radio channel which is characterized by AWGN, Multi-user interference (mUI) and frequency-selective rayleigh fading. System capacity i.e., number of user per cell has been derived and the evaluated results are shown in figuraes as a function of PN code sequence length, number of RAKE receiver tap, BER and E$_{b}$/N$_{o}$. The voice activity factor is assumed to be 3/8 the number of sectors in a cell 3 and MUI is modeled as gaussian process. From the results, the capacity of the DS-CDMA/DPSK cellular mobile communication system is improved by adopting CCI canceller. When we adopt the RAKE receiver to mitigate the multipath fading, the error performance is improved and the amount of improvement is proportional ot the number of taps L in the case that each tap contains a signal component and the better of improvement can be obtained, the smaller of the SNR difference in each tap. The system capacity is more increased when the CCI canceller and the RAKE receiver is used in cascade.

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A Parallel Video Encoding Technique for U-HDTV (U-HDTV를 위한 향상된 병렬 비디오 부호화 기법)

  • Jung, Seung-Won;Ko, Sung-Jea
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.48 no.1
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    • pp.132-140
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    • 2011
  • Ultra-High Definition Television (U-HDTV) is a promising candidate for the next generation television. Since the U-HDTV video signal requires a huge amount of data, parallel implementation of the U-HDTV compression system is highly demanding. In the conventional parallel video codec, a video is divided into sub-sequences and the sub-sequences are independently encoded. In this paper, for efficient parallel processing, we propose a pipelined encoding structure which exploits cross-correlation among the sub-sequences. The experimental results demonstrate that the proposed technique improves the coding efficiency and provides the sub-sequences of the balanced visual quality.