• Journal of the Institute of Convergence Signal Processing
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• v.9 no.3
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• pp.201-207
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• 2008

This paper presents the implementation of a Tiling System about Preprocessing functions of JPEG 2000. The system covers the JPEG 2000 standard and is designed to determine the size of the image, to expand the image area and to split input image into several tiles. In order to split the input image with the progressive transmission into several tiles and transmit a tile of this image to others, this system store this image into Frame Memory. Therefore, this is designed as the Finite State Machine (FSM) to sequence through specific patterns of states in a predetermined sequential manner by using Verilog-HDL and be designed to handle a maximum 5M image. Moreover, for identifying image size for expansion, we propose several formula which are based on remainder after division (rem). we propose the true table which determines the size of the image input patterns by using results of these formula. Under the condition of TSMC 0.25um ASIC library, gate count is 18,725 and maximum data arrival time is 18.94 [ns].

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.8 no.1
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• pp.42-51
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• 1997

The satellite channel with a line-of-sight signal component is modeled by a shadowed Rician fading channel. We adopt a direct-sequence / code division multiple access (DS / CDMA), which has the advantage to suppress the multipath effect and increase the user capacity. The performance which is evaluated by bit error probability is subjected to the influence of branch number, multi-user number, and spreading code-length. As the result of the analysis, performance advance is achieved with multi-user number decreasing, number of brnaches increasing, and spreading code-length increasing as chip duration is constant. To use both of diversity combining scheme and channel coding is more efficient for performance improvement than the case using diversity combining scheme only. The use of BCH coding and convolutional coding shows better consequence than Hamming coding. Totally, the performance degradation for heavy shadowing is much larger than that for light and average shadowing as heavy shadowing decreases LOS signal.

• Investigative Magnetic Resonance Imaging
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• v.20 no.4
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• pp.215-223
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• 2016

Purpose: The management of metal-induced field inhomogeneities is one of the major concerns of distortion-free magnetic resonance images near metallic implants. The recently proposed method called "Slice Encoding for Metal Artifact Correction (SEMAC)" is an effective spin echo pulse sequence of magnetic resonance imaging (MRI) near metallic implants. However, as SEMAC uses the noisy resolved data elements, SEMAC images can have a major problem for improving the signal-to-noise ratio (SNR) without compromising the correction of metal artifacts. To address that issue, this paper presents a novel reconstruction technique for providing an improvement of the SNR in SEMAC images without sacrificing the correction of metal artifacts. Materials and Methods: Low-rank approximation in each coil image is first performed to suppress the noise in the slice direction, because the signal is highly correlated between SEMAC-encoded slices. Secondly, SEMAC images are reconstructed by the best linear unbiased estimator (BLUE), also known as Gauss-Markov or weighted least squares. Noise levels and correlation in the receiver channels are considered for the sake of SNR optimization. To this end, since distorted excitation profiles are sparse, $l_1$ minimization performs well in recovering the sparse distorted excitation profiles and the sparse modeling of our approach offers excellent correction of metal-induced distortions. Results: Three images reconstructed using SEMAC, SEMAC with the conventional two-step noise reduction, and the proposed image denoising for metal MRI exploiting sparsity and low rank approximation algorithm were compared. The proposed algorithm outperformed two methods and produced 119% SNR better than SEMAC and 89% SNR better than SEMAC with the conventional two-step noise reduction. Conclusion: We successfully demonstrated that the proposed, novel algorithm for SEMAC, if compared with conventional de-noising methods, substantially improves SNR and reduces artifacts.

• Journal of Microbiology
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• v.40 no.2
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• pp.140-145
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• 2002

The 5.8 kb pMMH1, rolling-circle replication (RCR) plasmid of the wild type soil Bacillus mesentericus was developed into a novel secretion vector system in Bacillus subtilis. The pMMHl turned out to have a replication origin and two open reading frames (ORFs) of the putative γ-GTP and type I signal peptidase (sipP). To characterize the regions necessary for plasmid stability and high copy number, five vectors (pPS, pPP, pEN, pMN, pME) were constructed by disruption or deletion of each region in pMMH1. Like pMMHl all constructed vectors were stable over 100 generations In a non-selective medium. Since pPS was the smallest (2.3 kb)of all, it was selected for the construction of a navel secretion vector, Using the $\alpha$-amylase promoter/signal sequence of B. subtilils the novel plasmid pJSN was constructed. When $\beta$-glucosidase was expressed using pJSN, we found $\beta$-glucosidase activity in the medium. This result strongly suggested that plasmid pJSN can be used for the production of bioactive peptides in B. subtilis.

• Journal of the Institute of Convergence Signal Processing
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• v.2 no.1
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• pp.1-11
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• 2001

This paper presents a learning-based approach for the construction of license Plate recognition system. The system consist of three modules. They are respectively, car detection module, license plate recognition module and recognition module. Car detection module detects a car in the given image sequence obtained from the camera with simple color-based approach. Segmentation module extracts the license plate in detect car image using neural network as filters for analyzing the color and texture properties of license plate. Recognition module then reads characters in detected license plate with support vector machine (SVM)-based characters recognizer. The system has been tested from parking lot and tollgate, etc. and have show the following performances on average: Car detect rate 100%, segmentation rate 97.5%, and character recognition rate about 97.2%. Overall system performances is 94.7% and processing time is one sec. Then our propose system does well using real world.

• Journal of the Institute of Convergence Signal Processing
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• v.5 no.2
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• pp.159-164
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• 2004

This paper proposes a new digital filter implementation which adopts an identical structure at both behavioral and logic level in top-down design. This methodology is based on the observation that multiplication is a form of convolution and carrying, and therefore multiplication is implemented with the same structure as that of a convolution in a recursive manner at the logic level. In order to demonstrate a recursive structure-based FIR digital filter, we select L-tap transposed and systolic FIR filters, and implement them to have a single structure. The proposed filter design becomes regular and modular because of the recursive adoption of a single structure for convolutions, and is very compact in that it needs only two 1-bit I/O ports in addition to significant improvement on hardware complexity without time penalty on the output sequence.

• Genomics & Informatics
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• v.7 no.4
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• pp.195-202
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• 2009

BIRC5 (Survivin) belongs to the inhibitor of apoptosis gene family. The BIRC5 protein inhibits caspases and consequently blocks apoptosis. Thus, BIRC5 contributes to the progression of cancer allowing for continued cell proliferation and survival. In this study, we identified eight sequence variants of BIRC5 through direct DNA sequencing. Among the eight single nucleotide polymorphisms (SNPs), six common variants with frequencies higher than 0.05 were selected for larger-scale genotyping (n=1,066). Results of the study did not show any association between the promoter region polymorphisms and the clearance of hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC) occurrence. This is in line with a previous study in which polymorphisms in the promoter region does not influence the function of BIRC5. Initially, we were able to detect a signal with the ＋9194A>G, which disappeared after multiple corrections but led to a change in amino acid. Similarly, we were also able to detect an association signal between two haplotypes (haplotype-2 and haplotype-5) on the onset age of HCC and/or HCC occurrence, but the signals also disappeared after multiple corrections. As a result, we concluded that there was no association between BIRC5 polymorphisms and the clearance HBV infection and/or HCC occurrence. However, our results might useful to future studies.

• Journal of the Institute of Convergence Signal Processing
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• v.4 no.3
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• pp.34-40
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• 2003

The paper presents a method to detect dissolve shots of video scene change detections in an MPEG compressed domain. The proposed algorithm uses color-R DCT coefficients of Ⅰ, P-frames for a fast operation and accurate detection and a minimum decoding process in MPEG sequences. The paper presents a method to detect dissolve shot for three-dimensional visualization and analysis of Image in order to recognize easily in computer as a human detects accurately shots of scene change. First, Color-R DCT coefficients for 8*8 units are obtained and the features are summed in a row. Second, Four-step analysis are Performed for differences of the sum in the frame sequences. The experimental results showed that the algorithm has better detection performance, such as precision and recall rate, than the existing method using an average for all DC image by performing four step analysis. The algorithm has the advantage of speed, simplicity and accuracy. In addition. it requires less amount of storage.

• The Plant Pathology Journal
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• v.27 no.1
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• pp.89-92
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• 2011

Cyclic AMP receptor-like protein (Clp), is known to be a global transcriptional regulator for the expression of virulence factors in Xanthomonas campestris pv. campestris (Xcc). Sequence analysis showed that Xanthomonas oryzae pv. oryzae (Xoo) contains a gene that is strongly homologous to the Xcc clp. In order to determine the role of the Clp homolog in Xoo, a marker exchange mutant of $clp_{xoo4158}$ was generated. Virulence and virulence factors, such as the production of cellulase, xylanase, and extracellular polysaccharides (EPS) and swarming motility were significantly decreased in the $clp_{xoo4158}$ mutant. Moreover, the mutation caused the strain to be more sensitive to hydrogen peroxide and to over-produce siderophores. Complementation of the mutant restored the mutation-related phenotypes. Expression of $clp_{xoo4158}$, assessed by reverse-transcription realtime PCR and clp promoter activity, was significantly reduced in the rpfB, rpfF, rpfC, and rpfG mutants. These results suggest that the clp homolog, $clp_{xoo4158}$, is involved in the control of virulence and resistance against oxidative stress, and that expression of the gene is controlled by RpfC and RpfG through a diffusible signal factor (DSF) signal in Xanthomonas oryzae pv. oryzae KACC10859.

• Animal cells and systems
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• v.11 no.1
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• pp.39-50
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• 2007

Tau plays a role in numerous neuronal processes, such as vesicle transport, microtubule-plasma membrane interaction and intracellular localization of proteins. SUMO (Small Ubiquitin-like Modifier) modification (SUMOylation) appears to regulate diverse cellular processes including nuclear transport, signal transduction, apoptosis, autophagy, cell cycle control, ubiquitin-dependent degradation, as well as gene transcription. We noticed that putative SUMOylation site is localized at $^{340}K$ of $Tau(^{339}VKSE^{342})$ with the consensus sequence information (${\Phi}KxE$ ; where ${\Phi}$ represents L, I, V or F and x is any amino acid). In this report, we demonstrated that $^{340}K$ of Tau is the SUMOylation site and that a point mutant of Tau S214E (an analog of the phospho $^{214}S$ Tau) promotes its SUMOylation at $^{340}K$ and its nuclear or nuclear vicinity localization, by co-immunoprecipitation and confocal microscopy analysis. Further, we demonstrate that the Tau S214E (neither Tau S214A nor Tau K340R) mutant increases its protein stability. However, the SUMOylation at $^{340}K$ of Tau did not influence cell survival, as determined by FACS analysis. Therefore, our results suggested that the phosphorylation of Tau on $^{214}S$ residue promotes its SUMOylation on $^{340}K$ residue and nuclear vicinity localization, and increases its stability, without influencing cell survival.