• 대한방사선기술학회지:방사선기술과학
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• 제38권3호
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• pp.253-259
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• 2015

본 연구에서는 가돌리늄 조영제를 다양한 몰농도로 희석하여 T1 효과를 나타내는 펄스 시퀀스 중 고속스핀에코와 에코타임이 극도로 짧은 ultra short time echo에서 최대 신호 강도 분포를 나타내는 조영제 희석 몰농도를 3.0T에서 각각 알아보고자 하였다. T1 조영제인 gadoxetic acid 와 완충용액으로는 증류수, 2% agarose gel을 이용하여 다양한 몰농도로 조영제 팬텀을 제작하였다. 팬텀 제작의 정확성을 측정하기 위해 T1 이완시간 측정의 표준방식인 2D inversion recovery spine-echo 펄스시퀀스를 이용하였으며 팬텀의 중간 부의 한 개의 관상면 영상을 획득하여 T1 이완 시간을 계산하였다. 스핀에코에서는 1-2 mmol/L 조영제 몰농도에서 가장 높은 신호를 나타냈으며, ultra short time echo에서는 7 mmol/L에서 가장 큰 신호를 나타냈다. ultra short time echo 펄스 시퀀스를 이용한 조영증강 효과를 보기 위해서는 고속스핀에코 기법 보다 2-3배의 조영제 농도가 목적 장기에 유지하여야 하며 이와 관련된 조영제량 및 투여 방법의 연구가 이루어져야 한다.

• 한국통신학회논문지
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• 제32권2A호
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• pp.169-178
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• 2007

본 논문에서는 SC-FDE(Single Carrier with Frequency Domain Equalization) 시스템의 수신 성능을 최적화하기 위한 신호 구조와 수신기 설계 방안을 제안한다. 기존의 SC-FDE 시스템은 수신단에서 신호 복조를 위해 이용되는 파일럿 신호가 시간 영역에서 생성되기 때문에 주파수 영역 전력 분포가 불균일하여 채널 등화 과정에서의 오류를 발생시키며, 이는 수신기 성능 열화의 주요인으로 작용한다. 본 논문에서는 기존 방식의 단점을 보완하기 위해 시간과 주파수 영역 모두에서 전력 분포가 일정한 CAZAC(Constant Amplitude Zero Auto-Correlation) sequence를 응용하여 이를 반복하는 형태로 파일럿 신호를 생성함으로써 수신 성능을 향상시킬 수 있는 신호 구조를 설계하였으며, 이에 적합한 수신기 구조를 제시한다. 컴퓨터 시뮬레이션을 통해 이동 무선 채널 환경에서 제안된 구조가 기존의 구조에 비해 프레임과 주파수 동기 그리고 채널 등화의 관점에서 더욱 우수한 성능을 보임을 입증하였다.

• 한국해양공학회지
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• 제24권1호
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• pp.166-171
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• 2010

In this paper, the front-end of a digital receiver with a 25 kHz carrier frequency, 5 kHz symbol rate, and any excess-bandwidth is designed using two basic facts. The first is known as the uniform sampling theorem, which states that the sampled sequence might not suffer from aliasing even if its sampling rate is lower than the Nyquist sampling rate if the analog signal is a bandpass one. The other fact is that if the sampling rate is 4 times the center frequency of the sampled sequence, the front-end processing complexity can be dramatically reduced due to the half of the sampled sequence to be multiplied by zero in the demixing process. Furthermore, the designed front-end is simplified by introducing sub-filters and sub-sampling sequences. The designed front-end is composed of an A/D converter, which takes samples of a bandpass filtered signal at a 20 kHz rate; a serial-to-parallel converter, which converts a sampled bandpass sequence to 4 parallel sub-sample sequences; 4 sub-filter blocks, which act as a frequency shifter and lowpass filter for a complex sequence; 4 synchronized switches; and 2 adders. The designed front-end dramatically reduces the computational complexity by more than 50% for frequency shifting and lowpass filtering operations since a conventional front-end requires a frequency shifting and two lowpass filtering operations to get one lowpass complex sample, while the proposed front-end requires only four filtering operation to get four lowpass complex samples, which is equivalent to one filtering operation for one sample.

• 대한전자공학회논문지TC
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• 제40권11호
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• pp.17-26
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• 2003

시간영역 확산을 하는 순방향 링크 OFCDM 시스템에서 고출력 증폭기의 비선형 왜곡을 경감시키고자 IFFT단 부반송파의 다중레벨 입력신호를 clipping을 한 후 MPSK(Multilevel-PSK) 신호로 전송하는 기술을 적용한다. AWGN 채널에서 고출력 증폭기의 비선형 왜곡이 고려된 경우 extended m 부호열을 사용한 clipping OFCDM 시스템이 extended m 부호열을 사용한 OFCDM 시스템에 비해 N이 8, 16명인 경우 2.2㏈ 이상 성능이 우수하였다. Quasi-static 채널에서 고출력 증폭기의 비선형 왜곡이 고려된 경우 extended m 부호열을 사용한 clipping OFCDM 시스템이 extended m 부호열을 사용한 OFCDM 시스템에 비해 N이 8, 16명인 경우는 2㏈ 이상 우수하였다.

• Parasites, Hosts and Diseases
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• 제39권2호
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• pp.151-160
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• 2001

Randomly selected 435 clones from Acanthamoeba healyi cDNA library were sequenced and a total of 387 expressed sequence tags (ESTs) had been generated. Based on the results of BLAST search, 130 clones (34.4%) were identified as the genes enconding surface Proteins , enzymes for DNA, energy Production or other metabolism, kinases and phosphatases, protease, proteins for signal transduction, structural and cytoskeletal proteins, cell cycle related proteins, transcription factors, transcription and translational machineries, and transporter proteins. Most of the genes (88.5%) are newly identified in the genus Acanthamoeba. Although 15 clones matched the genes of Acanthamoeba located in the public databases, twelve clones were actin gene which was the most frequently expressed gene in this study. These ESTs of Acanthamoeba would give valuable information to study the organism as a model system for biological investigations such as cytoskeleton or cell movement, signal transduction, transcriptional and translational regulations. These results would also provide clues to elucidate factors for pathogenesis in human granulomatous amoebic encephalitis or keratitis by Acanthamoeba.

• ETRI Journal
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• 제19권1호
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• pp.1-12
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• 1997

In this paper, we present an improved multicarrier direct sequence (DS) code division multiple access (CDMA) scheme by modifying the system originally proposed by Kondo and Milstein [13]. In this modified system, different spreading sequences multiplied by a data sequence modulate different carriers. This is to prevent the multiple access capability from reducing when the fading characteristics of different carrier frequencies are highly correlated. We have derived a formula which determines the mean values of the relative received signal strength in a single carrier DS CDMA rake system and in a multicarrier DS-CDMA system. We present results on the comparison of the bit error rate (BER) performance of the two systems including the effect of correlation between fading characteristics of different frequencies under various multipath fading conditions. The results indicate that with 50 users the modified multicarrier DS CDMA system can achieve an uncoded irreducible BER of $1.7{\times}10^{-3}$ with an average received signal-to-noise ratio per bit of 10dB, which is better that $3.0{\times}10^{-3}$ achieved by the single carrier DS CDMA rake system, and also show that if multicarrier CDMA system is used with respect to single carrier CDMA system, the SNR gain is up to 4.5 dB for the uncode BER of $10^{-3}$ being achieved.

• BMB Reports
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• 제40권6호
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• pp.1095-1099
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• 2007

Endonuclease G (EndoG) is a mitochondrial non-specific nuclease that is highly conserved among the eukaryotes. Although the precise role of EndoG in mitochondria is not yet known, the enzyme is released from the mitochondria and digests nuclear DNA during apoptosis in mammalian cells. Schizosaccharomyces pombe has an EndoG homolog Pnu1p (previously named SpNuc1) that is produced as a precursor protein with a mitochondrial targeting sequence. During the sorting into mitochondria the signal sequence is cleaved to yield the functionally active endonuclease. From the analogy to EndoG, active extramitochondrial Pnu1p may trigger cell killing by degrading nuclear DNA. Here, we tested this possibility by expressing a truncated Pnu1p lacking the signal sequence in the extramitochondrial region of pnu1-deleted cells. The truncated Pnu1p was localized in the cytosol and nuclei of yeast cells. And ectopic expression of active Pnu1p led to cell death with fragmentation of nuclear DNA. This suggests that the Pnu1p is possibly involved in a certain type of yeast cell death via DNA fragmentation. Although expression of human Bak in S. pombe was lethal, Pnu1p nuclease is not necessary for hBak-induced cell death.

• BMB Reports
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• 제34권4호
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• pp.371-378
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• 2001

The Glycoprotein D (gD) gene of the HSV-1 strain F was cloned, sequenced, recombinated into the HcNPV (Hyphantria cunea nuclear polyhedrosis virus) expression vector and expressed in insect cells. The gD gene was located in the 6.43 kb BamHI fragment of the strainF. The open reading frame (ORF) of the gD gene was 1,185 by and codes 394 amino acid residues. Recombinant baculoviruses, GD-HcNPVs, expressing the gD protein were constructed. Spodoptera frugiperda cells, infected with the recombinant virus, synthesized a matured gX-gD fusion protein with an approximate molecular weight of 54 kDa and secreted the gD proteins into the culture media by an immunoprecipitation assay The fusion gD protein was localized on the membrane of the insect cells, seen by using an immunofluorescence assay The deduced amino acid sequence presents additional characteristics compatible with the structure of a viral glycoprotein: signal peptide, putative glycosylation sites and a long C-terminal transmembrane sequence. These results indicate the utility of the HcNPV-insect cell system for producing and characterizing eukaryotic proteins.

• 말소리와 음성과학
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• 제1권1호
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• pp.63-67
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• 2009

In this paper, in order to protect music copyrights, we propose a music identification system which is scalable to the number of pieces of registered music and robust to signal-level variations of registered music. For its implementation, we define the new concepts of 'music word' and 'music phoneme' as recognition units to construct 'music acoustic models'. Then, with these concepts, we apply the HMM-based framework used in continuous speech recognition to identify the music. Each music file is transformed to a sequence of 39-dimensional vectors. This sequence of vectors is represented as ordered states with Gaussian mixtures. These ordered states are trained using Baum-Welch re-estimation method. Music files with a suspicious copyright are also transformed to a sequence of vectors. Then, the most probable music file is identified using Viterbi algorithm through the music identification network. We implemented a music identification system for 1,000 MP3 music files and tested this system with variations in terms of MP3 bit rate and music speed rate. Our proposed music identification system demonstrates robust performance to signal variations. In addition, scalability of this system is independent of the number of registered music files, since our system is based on HMM method.

• 한국전자파학회논문지
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• 제18권1호
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• pp.90-95
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• 2007

LDR(Low Date Rate) UWB(Ultra Wide Band) 시스템에서 chaotic 신호를 이용한 OOK(On Off Keying) 통신 방법이 선택적 사항으로 채택되어 있다. 이 시스템에서 중요 회로 중에 하나인 chaotic 신호 발생 회로는 현재 대부분 아날로그 형태의 피드백 구조를 이용하고 있으나, 아날로그 형태의 피드백 구조는 공정 변화에 대한 취약점이 있어 양산성에 어려움이 있다. 이를 해결하기 위해 본 논문에서는 0.18 um CMOS 공정을 이용하여 디지털 구조의 PN-sequence를 응용하여 중심 주파수 4 GH에서 2 GHz의 대역폭을 갖는 Quasi-chaotic 신호 발생 회로를 설계 및 검증하였다.