• Journal of the Korea Institute of Information and Communication Engineering
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• v.20 no.8
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• pp.1407-1414
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• 2016

In this study, we develop that Location Recommending System using personal emotion information based on Collaborative Filtering. Previous Location Recommending System recommended a place visited by the user of the rating or the pattern of location for the user place. These systems are not high user satisfaction because that dose not consider the user status or have not objectively the information. Using user's personal emotion information to recommend a high-affinity users who have visited the place felt similar emotions objectively can improve user satisfaction with the place. In this study, a user using a mobile application directly register the recognized emotion information using the current position and bio-signal, and using the registered information measuring the similarity of user with a similarity emotion, predicts a preference for the place it is recommended to emotional place. The system consists of a user interface, a database, a recommendation module.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.6
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• pp.2812-2818
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• 2013

Medicine such as Korean oriental medicine and alternative medicine is inferior to western medicine in diagnostic skills and treatment regimen but despite going through a lot of in western medicine preference to that is situations. Likewise, in Korean oriental medicine and alternative medicine have been closely linked to that effect not proven scientifically to be solved is regarded as the biggest drawback. In this paper, auricular therapy that is often used in alternative medicine to help strengthen the internal organs function which whether the conduct of stimulating ear is effective or not by applying to ocular inspection of Korean oriental medicine is proposed. For this purpose, lung ear reflex points to stimulate were performed after the right cheek color by measuring stimulation before comparison and analysis of the experiments. In addition, in order to examine this first analysis of the human body to the lungs and the elements of image analysis is to study. Experimental result, derived b value increased to a value of the right cheek and the results by lung ear to stimulate reflex point.

• Journal of Microbiology and Biotechnology
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• v.26 no.2
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• pp.315-325
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• 2016

A novel esterase gene, est7K, was isolated from a compost metagenomic library. The gene encoded a protein of 411 amino acids and the molecular mass of the Est7K was estimated to be 44,969 Da with no signal peptide. Est7K showed the highest identity of 57% to EstA3, which is an esterase from a drinking water metagenome, when compared with the enzymes with reported properties. Est7K had three motifs, SMTK, YSV, and WGG, which correspond to the typical motifs of family VIII esterases, SxxK, Yxx, and WGG, respectively. Est7K did not have the GxSxG motif in most lipolytic enzymes. Three additional motifs, LxxxPGxxW, PLGMxDTxF, and GGxG, were found to be conserved in family VIII enzymes. The results of the phylogenetic analysis and the alignment study suggest that family VIII enzymes could be classified into two subfamilies, VIII.1 and VIII.2. The purified Est7K was optimally active at 40ºC and pH 10.0. It was activated to exhibit a 2.1-fold higher activity by the presence of 30% methanol. It preferred short-length p-nitrophenyl esters, particularly p-nitrophenyl butyrate, and efficiently hydrolyzed glyceryl tributyrate. It did not hydrolyze β-lactamase substrates, tertiary alcohol esters, glyceryl trioleate, fish oil, and olive oil. Est7K preferred an S-enantiomer, such as (S)-methyl-3-hydroxy-2-methylpropionate, as the substrate. The tolerance to methanol and the substrate specificity may provide potential advantage in the use of the enzyme in pharmaceutical and other biotechnological processes.

• Journal of Broadcast Engineering
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• v.24 no.6
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• pp.1024-1034
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• 2019

Preference for music is determined by a variety of factors, and identifying characteristics that reflect specific factors is important for music recommendations. In this paper, we propose a method to extract the singing voice related music features reflecting various musical characteristics by using a model learned for singer identification. The model can be trained using a music source containing a background accompaniment, but it may provide degraded singer identification performance. In order to mitigate this problem, this study performs a preliminary work to separate the background accompaniment, and creates a data set composed of separated vocals by using the proven model structure that appeared in SiSEC, Signal Separation and Evaluation Campaign. Finally, we use the separated vocals to discover the singing voice related music features that reflect the singer's voice. We compare the effects of source separation against existing methods that use music source without source separation.

• Investigative Magnetic Resonance Imaging
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• v.17 no.1
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• pp.1-7
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• 2013

Purpose : The purpose of this study is to correlate the imaging findings and the clinical findings in patients with transient splenial lesions (TSL). Materials and Methods: Total of 7 patients (M: F = 4: 3; age range 11 - 38 years, mean age 25.5 years) were studied between November 2006 and April 2011. The MRI findings and clinical findings in all patients were retrospectively reviewed. The location, MR signal intensity, restricted diffusion, enhancement pattern and reversibility from the follow up images were reviewed. Clinical features were reviewed with respect to the presented symptoms, signs, treatment and outcome. Results: The lesions were located in the splenium of corpus callosum in all patients. All lesions showed high signal intensity on diffusion weighted imaging (DWI), and six patients showed restricted diffusion on the apparent diffusion coefficient (ADC) map. ADC map was not available in one patient. All lesions (n = 7) showed high signal intensity on the T2 weighted image (T2WI). Five of the patients (71.4%) with follow up images (range 7 - 34 days) showed complete resolution of focal high signal intensity on DWI, with recovery of ADC values as well as T2WI. After contrast media administration, none of the lesions showed any enhancements. All lesions with various etiologies including TB medication were developed in younger age patients and showed reversibility after the acceptable period of minimum 7 days with conservative treatment. Conclusion: All TSL showed nonspecific imaging findings, including restricted diffusion on DWI and ADC map on the initial images. However, reversibility of the lesions and the young age preference can be a characteristic finding of TSL with acceptable period of minimum 7 days. In addition, to keep it in mind that various etiologies including TB medication may cause TSL, is important for radiologists as well as clinicians.

• Microbiology and Biotechnology Letters
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• v.38 no.4
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• pp.349-361
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• 2010

In this review, the current knowledge of the carbon metabolism and global carbon regulation in Corynebacterium glutamicum are summarized. C. gluamicum has phosphotransferase system (PTS) for the utilization of sucrose, glucose, and fructose. C. glutamicum does not show any preference for glucose when various sugars or organic acids are present with glucose, and thus cometabolizes glucose with other sugars or organic acids. The molecular mechanism of global carbon regulation such as carbon catabolite repression (CCR) in C. glutamicum is quite different to that in Gram-negative or low-GC Gram-positive bacteria. GlxR (glyoxylate bypass regulator) in C. glutamicum is the cyclic AMP receptor protein (CRP) homologue of E. coli. GlxR has been reported to regulate genes involved in not only glyoxylate bypass, but also central carbon metabolism and CCR including glycolysis, gluconeogenesis, and tricarboxylic acid (TCA) cycle. Therefore, GlxR has been suggested as a global transcriptional regulator for the regulation of diverse physiological processes as well as carbon metabolism. Adenylate cyclase of C. glutamicum is a membrane protein belonging to class III adenylate cyclases, thus it could possibly be a sensor for some external signal, thereby modulating cAMP level in response to environmental stimuli. In addition to GlxR, three additional transcriptional regulators like RamB, RamA, and SugR are also involved in regulating the expression of many genes of carbon metabolism. Finally, recent approaches for constructing new pathways for the utilization of new carbon sources, and strategies for enhancing amino acid production through genetic modification of carbon metabolism or regulatory network are described.