• Korean Journal of Pharmacognosy
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• v.34 no.2 s.133
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• pp.145-149
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• 2003

Many chemotherapeutic drugs were developed and contributed to the increase of cure rate of cancer, however severe side effect of these drugs is a major cause of poor quality of life of cancer patients. Effect of deer blood on cancer therapy was investigated in mouse tumor model. Deer blood itself was shown to have mild antitumor activity. However it has significant effect on the reduction of the side effects of chemotherapy. Deer blood recovered the reduction of WBC and platelet (myelotoxicity) during fluorouracil chemotherapy. Deer blood also recovered the increase of serum blood urea nitrogen (BUN; indicator of renal toxicity) and increase of serum amylase activity (AMY; indicator of pancreatic toxicity) almost to the control level during cisplatin chemotherapy. Fluorouracil and cisplatin are major chemotherapeutic drugs which are currently used in clinical cancer therapy, and the results strongly suggest that deer blood can be used for reducing the side effects and improving the quality of life during chemotherapy of cancer patients.

• Korean Journal of Biological Psychiatry
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• v.5 no.1
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• pp.114-121
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• 1998

Bethanechol, a cholinergic agonist, has been recommended for the management of peripheral anticholinergic side effects during the treatment of antipsychotic medications. But there have been few studies which have evaluated the drug interactions of antipsychotics and bethanechol, even the treatment effects of bethanechol on anticholinergic side effects. So the authors have evaluated whether psychopathology and plasma haloperidol and reduced haloperidol concentrations are significantly changed or not when bethanechol was administrated with maintained doses of haloperidol and other coadministrated drugs(such a benztropine). Also we have evaluated the abating effects of bethanechol on anticholinergic side effects during the treatment with haloperidol. Fifteen schizophrenics with higher than 5 of total score of anticholinergic side effects of 'Rating scale for side effect' were assigned to two groups, and bethanechol 30mg/day and 60mg/day were applied on each group for 4 weeks. The daily haloperidol dosages were fixed before 2 weeks of study. We assessed anticholinergic side effects by 'Rating scale for side effect' and psychopathology by BPRS, and plasma haloperidol and reduced haloperidol concentrations by HPLC at baseline, 2nd week and 4th week. The results were as followed, 1) there was no significant change of plasma haloperidol and reduced haloperidol concentration, 2) at baseline, the dosage of haloperidol showed significant correlation with the total score of anticholinergic side effect, but not at 2nd week and 4th week, 3) in 60mg/day group, dry mouth and the total score of anticholinergic side effects were significantly improved, but not in 30mg/day group, 4) there was no significant change of BPRS except withdrawal at 2nd week. These results suggest that coadministration of bethanechol influenced neither on psychopathology nor on plasma haloperidol and reduced haloperidol concentrations and that improved dry mouth and total score of anticholinergic side effects at 60mg/day.

• Journal of Korean Elementary Science Education
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• v.27 no.4
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• pp.437-445
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• 2008

The purpose of this study was to examine about science gifted class student's effect of education for the science gifted class. For this, 21 item-questionnaires were given to 292 students at the 4th, 5th and 6th graders in 3 elementary gifted schools located in Incheon. The results of this study were as follows: First, science gifted students were positive in effect of gifted class. This was more positive as class is low. Second, gifted students are thinking that it is helped to own learning that study at gifted class in cognitive side but appeared relatively low regarding school record or utterance, study method, thinking faculty, creativity. Third, they did not think that is exerting a lot of effects about own habit that study, interest, pride in emotional side. Fourth, they thought that is effective in relation with new friends more than teachers and parents in sociocultural side. Fifth, in private tutoring side they thought that is not influencing to solve academy taking a course of decrease.

• Journal of Korea Water Resources Association
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• v.48 no.8
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• pp.673-683
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• 2015

The existing flood protection in rivers has shown the limitation due to the urbanization around rivers and the abnormal climate. Thus, the demand for the constructions of side-weir detention basin are being increased as a part of integrated watershed flood protection plan. It is necessary to estimate the quantitative flood-control effect for including the side-weir detention basin in flood-control measures. For the determination, it is required to reduce the uncertainty of the design factors which can affect the flood-control effect of side-weir detention basin. Among the factors, however, the water level in river always contains uncertainty. Therefore, the design method considering the uncertainty is required. For the reasons, the design method considering uncertainty of the water level in river is suggested in this study with using the length of side-weir which is relatively easy-determinable by designers. Therefore, it is examined how the variation of the length of side-weir can affect the flood-control effect, using HEC-RAS, and then the method to determine the side-weir length considering the uncertainty of the water level in river through results from analyses. Since the uncertainty of the water level in river can be taken into account in the suggested design method, it is evaluated that the design method is more effective to suggest the flood-control effect of the side-weir type detention basin with higher safety side.

• International Journal of Automotive Technology
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• v.7 no.5
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• pp.585-593
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• 2006

The effect of the shape of the side wall on vaporization and fuel mixture were investigated for the impinging spray of a direct injection(DI) gasoline engine under a variety of conditions using the LIEF technique. The characteristics of the impinging spray were investigated under various configurations of piston cavities. To simulate the effect of piston cavity configurations and injection timing in an actual DI gasoline engine, the parameters were horizontal distance from the spray axis to side wall and vertical distance from nozzle tip to impingement plate. Prior to investigating the side wall effect, experiments on free and impinging sprays for flat plates were conducted and these results were compared with those of the side wall impinging spray. For each condition, the impingement plate was located at three different vertical distances(Z=46.7, 58.4, and 70 mm) below the injector tip and the rectangular side wall was installed at three different radial distances(R=15, 20, and 25 mm) from the spray axis. Radial propagation velocity from spray axis along impinging plate became higher with increasing ambient temperature. When the ambient pressure was increased, propagation speed reduced. High ambient pressures tended to prevent the impinging spray from the propagating radially and kept the fuel concentration higher near the spray axis. Regardless of ambient pressure and temperature fully developed vortices were generated near the side wall with nearly identical distributions, however there were discrepancies in the early development process. A relationship between the impingement distance(Z) and the distance from the side wall to the spray axis(R) was demonstrated in this study when R=20 and 25 mm and Z=46.7 and 58.4 mm. Fuel recirculation was achieved by adequate side wall distance. Fuel mixture stratification, an adequate piston cavity with a shorter impingement distance from the injector tip to the piston head should be required in the central direct injection system.

• Journal of Sericultural and Entomological Science
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• v.10
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• pp.27-33
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• 1969

This study was carried out to investigate the variation of mulberry yield in various parts of mulberry field. The results obtained from the study are summarized as follows. 1. For all the varieties, higher yield was observed side part than in the middle part. 2. With respect to the direction of field, the side faced south produced the highest yield, which was followed both side parts faced east and west. The side part fated north also produced relatively high yield. 3. No significant difference in yield was obtained between the central part and the near the each side, even the former seemed to be some what higher in yield than the latter. 4. Such a variety as Kaeryangsuban havins small leaves on many twigs with small internodes appeared to have more side effect than the otherwise variety, i.e. Rosang. 5. The variety Kaeryangsuban, showed more side effect in spring than in Autumm, however Rosang showed reversed effect. 6. Similar results were obtained in the leaf dry weight. 7. As a conclusion, it can he an important factor to increase yield to set up the mulberry field in east and west resulting less side effect.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.54 no.11
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• pp.557-560
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• 2005

This paper proposes the demand-side management(DSM) monitoring system of high efficient end-use equipments considering demand-side bidding (DSB). The effect on the market penetration of high efficient equipments by demand side bidding is analysed. Seasonal peak demand forecasting and penetration capacity of these equipments . are analysed.

• International Journal of Industrial Entomology and Biomaterials
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• v.26 no.2
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• pp.113-118
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• 2013

In this study, silk sericin films were prepared using different extraction methods, and the molecular conformation of sericin was examined using Fourier-transform infrared spectroscopy with attenuated total reflection geometry. Additionally, the effect of the film side (air-facing side or plate-facing side) on the molecular conformation of the sericin films was investigated. Interestingly, the molecular conformation of the sericin film depended on the film side. The molecular conformation of air-facing side of the sericin film was significantly influenced by extraction solution and time. The ${\beta}$-sheet crystallization and the crystallinity index of the sericin film markedly increased with an increase in the extraction time in hot water. The order of the crystallinity indices for the sericin films obtained with different extraction solutions was as follows: citric acid solution > urea solution >> hot water. In contrast, no remarkable differences were observed in the molecular conformation of the plate-facing side of the sericin film after extraction in hot water for different time periods. Urea and citric acid solution extractions showed remarkably higher crystallinity indices for sericin than those obtained after hot water extraction. However, no significant differences were observed in the crystallinity index of sericin between urea and citric acid solution extraction in plate-facing side of the film.

• The Journal of Korean Medicine
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• v.16 no.1 s.29
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• pp.71-95
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• 1995

To be helpful to the treatment of pulmonary cancer with oriental medicine, we got clinical reports together and analyzed the data. The results were obtained as follows: 1. The treating methods could be summarized as three methods that were reinforcing vital energy, eliminating harmful Qi, and reinforcing vital energy with eliminating harmful Qi. The methods of reinforcing vital energy were supplementing Qi & Yin, increasing pahological heat & reinforcing kidney, augmenting Qi & blood, supplementing vital energy and strengthening fundermental energy, reinforcing spleen and increasing Qi, lubricate Yin and lung, and the other methods of eliminating harmful Qi were transforming pathological fluid and softening, clarifying heat and eliminating poison, dipersing lung and softening, toxicding and softening, guiding Qi and activating blood, clarifying heat and dispersing lung, guiding Qi and counteracting stress etc., and the methods of supplementing vital energy with eliminating poison were reinforcing spleen and transforming pathological fluid, increasing Qi and activating blood, supplementing Yin and clarifying heat, reinforcing spleen and dry the dampness, lubricating lung and transforming patholigical fluid and supplementing Qi and activating blood. 2. The oriental prescriptions used for pulmonary cancer were Chunkeum-Weekyungtang & Sohamhwingtang, Jinhayookgunjatang, Hyulboochukeotang, Bokbangkyogonamtang was reported to be effective in the treatment of metastasis. 3. Bokbangshinjingtang and haewool were applied for the complications of pulmonary cancer, Soshihotang for fever, hangamryung for tumor pain. Prunus ansu Komarov, Eriobotrya japonica Lirdley, Pyrrosiae lingua Farwel, Steomon japonica Miguel, Maximowiczia chinensis Ruprecht var, Morus bombycis Koidzumi for cough, Panax Pseudo-ginseng Wall. var, Bletilla striata Reichenbach f., Acacia catechu(兒茶) for hemoptysis, Lonicerae flos, Aspongopus chinensis(九香蟲) for chest pain, Cypsum Fibrosum, Gazella gutturosa, Scutellaria baicalensis Georgi, Gypsophila oldhamiana Miquel for fever, Lepidii semen descurainiae semen, Belamcanda chinensis D.C, Gnaphalium affine(佛耳草) for asthma. 4. For the reduction of side effect by chemotherapy and radiotherapy it was known that supplementing Qi was used chiefly for side effect of chemotherapy and augmenting Yin applied to side effect of radiotherapy. 5. The oriental presciptions were suggested for the side effect by chemotherapy and radiotherapy ; Sammaekaek(參麥液), Whaebokwontang(化瘀復元湯), Hwangjungomitang(黃精五味湯), Yukmijihwangtang(六味地黃湯), Hyangsayukgunjatang(香砂六君子湯), Samlyeekulsan for side effect by chemotherapy while Geumgweisingiwhan, Hwanglyentang(黃連湯), Hwanglyenhaedoktang(黃連解毒湯), Yangyeunchungpeitang(養陰淸肺湯), Idongtang(二冬湯), Jayeunkanghwatang(滋陰降火湯) for side effect by radiotherapy.

• Journal of Ocean Engineering and Technology
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• v.15 no.3
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• pp.63-68
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• 2001

SG-365 steel is an important material and used for manufacturing a pressure vessel which the gas piping. In this investigation, the elastic plastic fracture toughness of this material is evaluated by the an unloading compliance method according to the ATM E813-97 method on the smooth and side groove 1CT specimens. The effect of smooth and side groove is studied on the elastic plastic fracture toughness. The side grooved specimen is very useful in estimation of the $J_IC. Because it is much easier than the smooth specimen to the onset of the ductile tearing by the R curve method. Besides, it improves the accuracy of toughness values, decreases the scattering of them and tunneling and shear lip by the side groove.