• Proceedings of the KOSOMBE Conference
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• v.1993 no.11
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• pp.121-123
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• 1993

• Steel and Composite Structures
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• v.26 no.2
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• pp.241-253
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• 2018

Mode II fracture toughness, $K_{IIC}$, of single-ply triaxially woven fabric (TWF) composite due to tow waviness and anisotropy effects were numerically and experimentally studied. The numerical wavy beam network model with anisotropic material description denoted as TWF anisotropic was first validated with experimental Mode II fracture toughness test employing the modified compact tensile shear specimen configuration. 2D planar Kagome and TWF isotropic models were additionally constructed for various relative densities, crack lengths, and cell size parameters for examining effects due to tow waviness and anisotropy. $K_{IIC}$ generally increased with relative density, the inverse of cell size, and crack length. It was found that both the waviness and anisotropy of tow inflict a drop in $K_{IIC}$ of TWF. These effects were more adverse due to the waviness of tow compared to anisotropy.

• Proceedings of the KSME Conference
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• 2004.11a
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• pp.1510-1515
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• 2004

Aggregability of red blood cells (RBCs) was determined by a laser backscattering light analysis in a microfluidic channel. Available techniques for RBC aggregation often adopt a rotational Couette-flow using bob-and-cup system for disaggregating RBCs, which causes the system to be complex and expensive. A disposable microfluidic channel and vibration generating mechanism were used in the proposed new detection system for RBC aggregation. Prior to measurement, RBC aggregates in a blood sample were completely disaggregated by applying vibration-induced shear. With the present apparatus, the aggregation indexes of RBCs can be easily measured with small quantities of blood sample. The measurements with the present aggregometer were compared with those of LORCA and showed a strong correlation between them. The aggregability of the defibrinogenated blood RBCs is markedly lower than that of the normal RBCs. The noble feature of this design is the vibration-induced disaggregation mechanism, which enables to incorporate disposable element that holds the blood sample.

• Tribology and Lubricants
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• v.15 no.3
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• pp.272-277
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• 1999

The objective of this investigation is to examine the influence of the micro catheters, which mimic the intravascular micro active endoscopes, on local pressure changes and flow rate in an arterial branch model similar to the femoral artery of human. The effects of branch to main lumen flow rate ratios and the locations of a catheter tip were found to be significant on the local pressure changes. Relatively large pressure drops and an increase in shear stress due to the obstruction effects may induce an endothelial cell damage and a change in arterial wall permeability, which have been reported to be the primary cause of the initiation of the atherosclerosis and other major vascular diseases.

• Tribology and Lubricants
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• v.14 no.1
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• pp.94-98
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• 1998

혈관내피세포는 혈관의 내벽에 단일 층을 구성하고 있는 상피세포로 동맥경화나 혈관협착의 원인에 매우 중요한 역할을 하는 것으로 알려져 있다. 그리고, 모든 혈관 질환의 발생장소가 혈관이 나뉘는 분지부에 집중되고 있어, 혈류역학과 혈관질환 간에 상호연관성이 있음을 짐작할 수 있다. 특히, 최근에 와서 혈관내피세포가 혈액유동에 의해 발생하는 전단응력을 인지하여 혈관의 제반 생리적 반응을 조절한다는 연구결과가 속속 발표되고 있어, 혈관질환의 극복을 위한 연구 개발에 혈관내피세포에 대한 이해의 중요성이 증대되고 있다. 이에 본 연구에서는 혈관내피세포에 혈류와 같은 크기의 전단응력을 부가하여 세포의 생리적 반응을 고찰할 수 있는 평판형 층류발생장치를 설계, 제작하였다. 설계된 평판형 층류발생장치는 유동환경 하에서의 혈관내피세포의 동적반응을 고찰 할 수 있도록 유동액의 온도, 산도, 전단응력의 크기를 조절할 수 있도록 설계하였으며, 제작된 실험장치를 이용하여 전단응력에 의한 혈관내피세포의 형태변화를 고찰하였다. 개발된 층류발생장치는 혈관내피세포의 연구 뿐 아니라, 백혈구의 점착, 암세포의 전이등에도 다양하게 활용이 가능하다.

• Proceedings of the Korea Concrete Institute Conference
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• 2009.05a
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• pp.27-28
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• 2009

In earthquake simulation tests of building structures, it is sometimes necessary to measure the shear forces in two orthogonal directions and axial force of a particular member. This study shows the manufacture and calibration of load cells for measuring 2-direction shears and uniaxial compression.

• Proceedings of the Korea Concrete Institute Conference
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• 1997.10a
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• pp.575-580
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• 1997

This study presents the techniques to manufacture the model concrete and model reinforcement for the 1/5-scale 3-story reinforced concrete frame. The used model concrete has sufficient workability but shows a little lower strength than expected model steel was made of commercial $\phi$3.2mm and $\phi$2.0mm wire by using deforming device and vacuum tube electric furnace. The yield strength can be simulated but it was difficult to simulate the other properties. The load cell was specially manufactured to measure the shear force in the columns of the first story. The carrying frame and the hinge adapter of artificial mass are explained. The special problems in the process of construction of model are also dressed.

• Bulletin of the Korean Chemical Society
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• v.35 no.1
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• pp.123-128
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• 2014

In this study, we have investigated the flow rate effects of Ag nanoparticle (NP) suspensions on the progress of the cell cycle by using a microfluidic image cytometry (${\mu}FIC$)-based approach. Compared with the conventional "static" exposure conditions, enhancements in G2 phase arrest were observed for the cells under continuously flowing "dynamic" exposure conditions. The "dynamic" exposure conditions, which mimic in vivo systems, induced an enhanced cytotoxicity by accelerating G2 phase arrest and subsequent apoptosis processes. Moreover, we have also shown that the increases in delivered NP dose due to the continuous supply of Ag NPs contributed dominantly to the enhanced cytotoxicity observed under the "dynamic" exposure conditions, while the shear stress caused by these slowly flowing fluids (i.e., flow rates of 6 and $30{\mu}L/h$) had only a minor influence on the observed enhancement in cytotoxicity.

• Journal of the Korean Graphic Arts Communication Society
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• v.28 no.2
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• pp.45-56
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• 2010

The computer simulation is presented of gravure ink transferring behavior and penetration to the paper when an gravure roller is used to transfer a printing ink onto a substrate. The three dimensional unsteady ink motion is simulated by Polyflow package software and experimented by IGT gravure printing test machine. The simulation is performed where the flow domain is bounded above by a stress free surface and bounded below by a moving substrate. Specific predictions are made for particular pattern of cells and substrates. Cell size and ink rheological properties are found to be the principal determination of transferring behavior. Simulation is currently restricted to the flow domain beneath the receding meniscus. Both Newtonian and shear thinning inks are considered.

• YAKHAK HOEJI
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• v.31 no.5
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• pp.308-314
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• 1987

In cardiovascular disease the flow adaptation of erythrocytes can be affected by reduced shear stresses and metabolic influences on red cell fluidity as a consequence of tissue hypoxia. In addition there are indications that risk factors of cardiovascular diseases are able to decrease the intrinsic red cell deformability. Erythrocyte deformability was studied by the filtration technique of Reid et al. to investigate the relationship between blood pressure chances and erythrocyte deformability. In this experiment normotensive rats, spontaneously and DOCA-salt treated hypertensive rats were used. Erythrocyte deformability was significantly reduced by blood pressure elevation in hypertensive rats but was not fully recovered by normalization of blood pressure after antihypertensive drug treatment. Therefore other factors than blood pressure may be involved in erythrocyte deformability reduction during blood pressure elevation.