• 제목/요약/키워드: serious loss

검색결과 682건 처리시간 0.028초

오인된 심부 정맥 혈전증에 대하여 항응고제 투여 후 발생한 급성 구획 증후군 (Acute Compartment Syndrome after Anticoagulant Therapy to Misdiagnosed Deep Vein Thrombosis)

  • 황석하;전호승;우영균;임성태
    • 대한정형외과학회지
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    • 제54권2호
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    • pp.177-181
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    • 2019
  • 급성 구획 증후군은 정형외과적 응급 질환이며, 구획 내의 압력이 증가하여 비가역적인 조직의 괴사를 유발한다. 이것은 기능적 장애, 하지의 손실 및 심할 경우 신 기능 저하를 유발하여 사망까지 이를 수 있다. 환자가 초기에 통증과 종창을 호소하는 경우 심부 정맥 혈전증과 유사하여 두 질환 간의 감별이 매우 중요하다고 알려져 있다. 저자들은 마사지 후 좌측 하퇴부의 통증과 종창을 보이는 환자를 심부 정맥 혈전증으로 오인하였고 항응고제를 투여하여 발생한 급성 구획 증후군에 근막 절개술을 시행하였고 만족스러운 치료 결과를 얻었으며, 문헌 고찰과 함께 본 증례를 보고하고자 한다.

갑상선 기능 저하증을 동반한 비만 환자에게 반하백출천마탕 투여 후 호전된 증례 2예 (Korean Medicine Treatment (Banhabakchulchunma-tang) for an Obese Patient With Hypothyroidism: Two Case Reports)

  • 심상송;박인혜;박창은;정원석
    • 한방비만학회지
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    • 제23권1호
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    • pp.42-50
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    • 2023
  • 본 증례보고는 갑상선 기능 저하증을 동반한 비만 환자 2명에게 반하백출천마탕(半夏白朮天麻湯加味方)을 투여하여 각각 77일, 66일 동안의 치료기간 동안 각각 6.5 kg, 4.5 kg의 체중 감 량의 효과 및 소증의 개선을 보였으며, 증례 2의 경우 갑상선 기능의 개선 또한 관찰하였다. 이와 같이 갑상선 기능 저하증의 환자에게 단독 한약치료를 시행하여 유의미한 효과를 보였기에 이를 보고하는 바이다.

최저가입찰제 및 실적공사비적산 환경에서의 대응방안 (The Corresponding Plan for Integrated Environment-the Lowest Cost Bid and The Current Cost Estimate System)

  • 김병수
    • 대한토목학회논문집
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    • 제26권5D호
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    • pp.849-859
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    • 2006
  • 최근 국내 건설업체는 최저가입찰제와 실적공사비적산제도로 인하여 수익성에 심각한 타격이 예상되고 있다. 2005년 최저가낙찰공사의 평균낙찰률은 60% 이하로 업체의 실행에도 못 미치는 수준이라고 할 수 있다. 이러한 낮은 낙찰률로 인하여 부실시공, 저가하도급, 연쇄적 기업손실 등 많은 문제점이 도출되고 있다. 여기에 정부발주 계약단가를 실적단가로 사용하는 실적공사비적산제도의 확대실시로 건설업체의 수익성은 더욱 악화될 것으로 판단된다. 본 연구는 이러한 환경에서 외국의 입찰제도를 국내제도와 비교 고찰하고 최저가입찰제와 실적공사비적산제도의 상관관계를 분석함으로써 입낙찰 제도적 측면 및 건설업체의 대응방안을 제시하여 국내 건설업체들이 향후 대응방향을 설정하는데 도움을 주고자 하였다.

Studies on QTLs for Bakanae Disease Resistance with Populations Derived from Crosses between Korean japonica Rice Varieties

  • Dong-Kyung Yoon;Chaewon Lee;Kyeong-Seong Cheon;Yunji Shin;Hyoja Oh;Jeongho Baek;Song-Lim Kim;Young-Soon Cha;Kyung-Hwan Kim;Hyeonso Ji
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2022년도 추계학술대회
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    • pp.201-201
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    • 2022
  • Rice bakanae disease is a serious global threat in major rice-cultivating regions worldwide causing high yield loss. It is caused by the fungal pathogen Fusarium fujikuroi. Varying degree of resistance or susceptibility to bakanae disease had been reported among Korean japonica rice varieties. We developed a modified in vitro bakanae disease bioassay method and tested 31 Korean japonica rice varieties. Nampyeong and Samgwang varieties showed highest resistance while 14 varieties including Junam and Hopum were highly susceptible with 100% mortality rate. We carried out mapping QTLs for bakanae disease resistance with four F2:F3 populations derived from the crosses between Korean japonica rice varieties. The Kompetitive Allele-Specific PCR (KASP) markers developed in our laboratory based on the SNPs detected in Korean japonica rice varieties were used in genotyping F2 plants in the populations. We found four major QTLs on chromosome 1, 4, 6, and 9 with LOD scores of 21.4, 6.9, 6.0, and 60.3, respectively. In addition, we are doing map-based cloning of the QTLs on chromosome 1 and 9 which were found with Junam/Nampyeong F2:F3 population and Junam/Samgwang F2:F3 population, respectively. These QTLs will be very useful in developing bakanae disease resistant high quality rice varieties.

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Elastic local buckling behaviour of corroded cold-formed steel columns

  • Nie Biao;Xu Shanhua;Hu WeiCheng;Chen HuaPeng;Li AnBang;Zhang ZongXing
    • Steel and Composite Structures
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    • 제48권1호
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    • pp.27-41
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    • 2023
  • Under the long-term effect of corrosive environment, many cold-formed steel (CFS) structures have serious corrosion problems. Corrosion leads to the change of surface morphology and the loss of section thickness, which results in the change of instability mode and failure mechanism of CFS structure. This paper mainly investigates the elastic local buckling behavior of corroded CFS columns. The surface morphology scanning test was carried out for eight CFS columns accelerated corrosion by the outdoor periodic spray test. The thin shell finite element (FE) eigen-buckling analysis was also carried out to reveal the influence of corrosion surface characteristics, corrosion depth, corrosion location and corrosion area on the elastic local buckling behaviour of the plates with four simply supported edges. The accuracy of the proposed formulas for calculating the elastic local buckling stress of the corroded plates and columns was assessed through extensive parameter studies. The results indicated that for the plates considering corrosion surface characteristics, the maximum deformation area of local buckling was located at the plates with the minimum average section area. For the plates with localized corrosion, the main buckling shape of the plates changed from one half-wave to two half-wave with the increase in corrosion area length. The elastic local buckling stress decreased gradually with the increase in corrosion area width and length. In addition, the elastic local buckling stress decreased slowly when corrosion area thickness was relatively large, and then tends to accelerate with the reduction in corrosion area thickness. The distance from the corrosion area to the transverse and longitudinal centerline of the plate had little effect on the elastic local buckling stress. Finally, the calculation formula of the elastic local buckling stress of the corroded plates and CFS columns was proposed.

톱밥 및 요소의 투입이 감자 더뎅이병 병원균(Streptomyces scabiei) 및 감자 더뎅이병 이병도 지수에 미치는 영향 (Effects of Sawdust and Urea Application on Disease Severity and Streptomyces scabiei Pathogen Dynamics)

  • 백계령;이정태;지삼녀
    • 한국환경과학회지
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    • 제32권11호
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    • pp.777-788
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    • 2023
  • Potato common scab disease is caused by pathogens belonging to Streptomyces spp. and results in a serious yield loss worldwide. Despite decades of research aimed at disease management, a definitive control method remains undiscovered. This study aims to explore the correlation between the C/N ratio and urea application with potato common scab pathogen dynamics and disease severity. We applied sawdust with a high C/N ratio and urea into the soil prior to potato cropping, both in pot and field experiments. Disease severity assessments and quantification of the TxtB gene were conducted at the harvest stage. Furthermore, culture experiments were performed to assess the direct impact of urea on the pathogen. Our findings revealed that higher disease severity was correlated with a high C/N ratio application and pathogenic gene quantity. Urea exhibited a direct influence on S. scabiei activity, reducing the disease severity in pot experiments. However, the effects of urea application on disease suppression in the conductive field were inconclusive. Although the results of urea application experiments displayed inconsistencies between pot and field trials, urea worked as the control to suppress S. scabiei activity. Further investigations are needed under various field conditions to confirm these findings.

비균일 음속 다중경로환경에서 선배열 센서를 이용한 근거리 표적의 3차원 위치추정 기법 (3-D Near Field Localization Using Linear Sensor Array in Multipath Environment with Inhomogeneous Sound Speed)

  • 이수형;최병웅
    • 한국음향학회지
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    • 제25권4호
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    • pp.184-190
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    • 2006
  • 최근에 Lee 등은 1차원 수평배열 센서만을 사용하여 다중경로를 통해 들어오는 신호로부터 표적의 3차원 위치를 추정하였다. 그러나 이 기법에서 음속은 수심에 상관없이 일정하다고 가정하였기 때문에 음속이 수심에 따라 다양하게 변화하는 실제 해양환경에서는 그 추정 성능이 현저하게 저하된다. 따라서 본 논문에서는 비균일 음속 환경에 적합한 근거리 표적의 3차원 위치추정 기법을 제안한다. 제안한 기법에서는 선형의 음속구조를 가지는 근거리 다중경로 환경에서 음파전달 모델을 기반으로 한 위치추정함수를 구성하였으며 이로부터 표적의 방위각, 거리 및 깊이를 3차원 탐색을 통하여 추정하였다. 선형 음속구조 및 실제 환경과 유사한 비선형 음속구조를 적용하여 제안한 기법의 성능을 기존의 기법과 비교, 분석하였으며 기존의 기법에 비해 거리 추정 오차는 최대 100m, 깊이 추정 오차는 50m정도 감소됨을 확인하였다.

규칙적인 신체활동과 운동중재가 노인의 우울증에 미치는 영향분석 (Combined Impacts of Physical Activity and Exercise on Depression in Elderly People)

  • 오정윤;양정옥;곽이섭
    • 생명과학회지
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    • 제34권3호
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    • pp.208-213
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    • 2024
  • 본 연구는 노인의 우울증 예방 및 치료를 위해 신체활동과 운동이 어떠한 효과가 있는지를 확인하는 것이다. 전 세계적으로 우울증은 지속적으로 증가하는 추세이며 특히 가속화되어 가는 고령화 사회에서 노인의 우울증은 더욱 심각한 문제라고 볼 수 있다. 노인의 우울증은 젊은 층에 비해 예후가 좋지 않으며 노화로 인한 신체적 질병의 증가와 신체적 장애에 의한 자존감 저하로 더욱 취약하다고 할 수 있다. 그러나 노인들의 우울증 관리, 노쇠로 인한 우울증 등의 문제에도 불구하고 지금까지 예방 및 치료에 관한 연구는 미미하다고 판단된다. 따라서 본 연구는 중요한 매개 변인인 수면장애와 우울증, 우울증에 대한 운동과 해마의 연관성, 우울증 관리를 위한 신체활동 및 운동의 과학적 효과를 분석하였다. 추후 노인의 우울증 개선과 자살예방에 관한 다양한 연구들이 수행되어져야 할 것으로 여겨진다.

봉독이 피부 노화에 미치는 영향 (The Effect of Bee Venom Therapy on Skin Aging)

  • 김진명;김윤범
    • 한방안이비인후피부과학회지
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    • 제23권2호
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    • pp.27-40
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    • 2010
  • Background and Objective : Increasing interest in anti-aging and anti-wrinkling agents for the skin has triggered the recent outflow of researches and studies in this field. This study was designed to investigate the effects of bee venom on skin wrinkling and skin aging by testing the skin wrinkling, skin elasticity, trans-epidermal water loss (TEWL), free radical level, anti-oxidative agent level, and skin tissue after infusion of bee venom on hairless mouse. Materials and Methods : Fifteen hairless mice aged between 36~40 weeks were divided randomly into 3 Group; the Bee Venom Syringe Group, the Bee Venom Needle Group, and the control group. The Bee Venom Syringe Group were injected subcutaneously with bee venom (0.1cc in total) using an insulin syringe on three spots in the lumbar spine (one spot on the center and two spots 1~2cm to the side bilaterally). The Bee Venom Needle Group were pricked with bee venom-smeared acupuncture needles on three longitudinal spots in the lumbar spine each 1cm apart, after which the needles were removed 10 minutes later. The Control Group did not receive any form of intervention. All procedures took place thrice a week for four weeks, during which the mice were allowed free access to water and fodder. The mice were measured and compared in the weight, skin wrinkling scale, skin elasticity, and TEWL before and after the experiment. After the experiment, blood samples were taken to measure the free radical and anti-oxidative agent level, and the skin tissue was sliced for examination. Data was analyzed using the SPSS program (ver 12.0). The ANOVA analysis was used to compare and contrast the three groups, and t-test for paired samples was used to evaluate skin-wrinkling before and after experiment. The cut-off p-value of significance was set at p<0.05. Results : 1. Administration of bee venom did not cause serious weight loss or gain. 2. Compared to the control group, the Bee Venom Syringe Group and the Bee Venom Needle Group both showed a decrease in skin wrinkling scale after intervention. Especially, the Bee Venom Syringe Group showed a significant decrease (p<0.05). 3. Compared to the control group, the Bee Venom Syringe Group and the Bee Venom Needle Group both showed an increase in skin elasticity. Especially, the Bee Venom Syringe Group showed a significant increase (p<0.05). 4. No significant change in TEWL was found in the mice in all the three groups before and after experiment. 5. Free radical level was normal in all 15 mice in all the three groups, and anti-oxidative agent was not significantly different across the three groups. 6. The Bee Venom Syringe Group, the Bee Venom Needle Group, and the control group did not show any significant difference in the thickness of epidermis and dermis, infiltration of inflammatory cells, and skin wrinkling. The epidermis layer was relatively better preserved in the Bee Venom Syringe Group as compared to the Bee Venom Needle Group and the control group. Conclusion : Direct injection of bee venom on the hairless mouse using a syringe was found to improve wrinkling of the skin and increase skin elasticity but did not show effectiveness on skin dryness due to water loss. The bee venom appears to have suppressive effects on skin wrinkling, one of the symptoms of skin aging, through a process independent of suppression of free radicals or increase of anti-oxidative agent.

Considerations of Environmental Factors Affecting the Detection of Underwater Acoustic Signals in the Continental Regions of the East Coast Sea of Korea

  • Na, Young-Nam;Kim, Young-Gyu;Kim, Young-Sun;Park, Joung-Soo;Kim, Eui-Hyung;Chae, Jin-Hyuk
    • The Journal of the Acoustical Society of Korea
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    • 제20권2E호
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    • pp.30-45
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    • 2001
  • This study considers the environmental factors affecting propagation loss and sonar performance in the continental regions of the East Coast Sea of Korea. Water mass distributions appear to change dramatically in a few weeks. Simple calculation with the case when the NKCW (North Korean Cold Water) develops shows that the difference in propagation loss may reach in the worst up to 10dB over range 5km. Another factor, an eddy, has typical dimensions of 100-200km in diameter and 150-200m in thickness. Employing a typical eddy and assuming frequency to be 100Hz, its effects on propagation loss appear to make lower the normal formation of convergence zones with which sonars are possible to detect long-range targets. The change of convergence zones may result in 10dB difference in received signals in a given depth. Thermal fronts also appear to be critical restrictions to operating sonars in shallow waters. Assuming frequency to be 200Hz, thermal fronts can make 10dB difference in propagation loss between with and without them over range 20km. An observation made in one site in the East Coast Sea of Korea reveals that internal waves may appear in near-inertial period and their spectra may exist in periods 2-17min. A simulation employing simple internal wave packets gives that they break convergence zones on the bottom, causing the performance degradation of FOM as much as 4dB in frequency 1kHz. An acoustic experiment, using fixed source and receiver at the same site, shows that the received signals fluctuate tremendously with time reaching up to 6.5dB in frequencies 1kHz or less. Ambient noises give negative effects directly on sonar performance. Measurements at some sites in the East Coast Sea of Korea suggest that the noise levels greatly fluctuate with time, for example noon and early morning, mainly due to ship traffics. The average difference in a day may reach 10dB in frequency 200Hz. Another experiment using an array of hydrophones gives that the spectrum levels of ambient noises are highly directional, their difference being as large as 10dB with vertical or horizontal angles. This fact strongly implies that we should obtain in-situ information of noise levels to estimate reasonable sonar performance. As one of non-stationary noise sources, an eel may give serious problems to sonar operation on or under the sea bottoms. Observed eel noises in a pier of water depth 14m appear to have duration time of about 0.4 seconds and frequency ranges of 0.2-2.8kHz. The 'song'of an eel increases ambient noise levels to average 2.16dB in the frequencies concerned, being large enough to degrade detection performance of the sonars on or below sediments. An experiment using hydrophones in water and sediment gives that sensitivity drops of 3-4dB are expected for the hydrophones laid in sediment at frequencies of 0.5-1.5kHz. The SNR difference between in water and in sediment, however, shows large fluctuations rather than stable patterns with the source-receiver ranges.

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