• 제목/요약/키워드: sequence-to-sequence model

검색결과 1,626건 처리시간 0.03초

Analyses of Expressed Sequence Tags from Chironomus riparius Using Pyrosequencing : Molecular Ecotoxicology Perspective

  • Nair, Prakash M. Gopalakrishnan;Park, Sun-Young;Choi, Jin-Hee
    • Environmental Analysis Health and Toxicology
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    • 제26권
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    • pp.10.1-10.7
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    • 2011
  • Objects: Chironomus riparius, a non-biting midge (Chironomidae, Diptera), is extensively used as a model organism in aquatic ecotoxicological studies, and considering the potential of C. riparius larvae as a bio-monitoring species, little is known about its genome sequences. This study reports the results of an Expressed Sequence Tags (ESTs) sequencing project conducted on C. riparius larvae using 454 pyrosequencing. Method: To gain a better understanding of C. riparius transcriptome, we generated ESTs database of C.ripairus using pyrosequencing method. Results: Sequencing runs, using normalized cDNA collections from fourth instar larvae, yielded 20,020 expressed sequence tags, which were assembled into 8,565 contigs and 11,455 singletons. Sequence analysis was performed by BlastX search against the National Center for Biotechnology Information (NCBI) nucleotide (nr) and uniprot protein database. Based on the gene ontology classifications, 24% (E-value${\leq}1^{-5}$) of the sequences had known gene functions, 24% had unknown functions and 52% of sequences did not match any known sequences in the existing database. Sequence comparison revealed 81% of the genes have homologous genes among other insects belonging to the order Diptera providing tools for comparative genome analyses. Targeted searches using these annotations identified genes associated with essential metabolic pathways, signaling pathways, detoxification of toxic metabolites and stress response genes of ecotoxicological interest. Conclusions: The results obtained from this study would eventually make ecotoxicogenomics possible in a truly environmentally relevant species, such as, C. riparius.

Residual seismic performance of steel bridges under earthquake sequence

  • Tang, Zhanzhan;Xie, Xu;Wang, Tong
    • Earthquakes and Structures
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    • 제11권4호
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    • pp.649-664
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    • 2016
  • A seismic damaged bridge may be hit again by a strong aftershock or another earthquake in a short interval before the repair work has been done. However, discussions about the impact of the unrepaired damages on the residual earthquake resistance of a steel bridge are very scarce at present. In this paper, nonlinear time-history analysis of a steel arch bridge was performed using multi-scale hybrid model. Two strong historical records of main shock-aftershock sequences were taken as the input ground motions during the dynamic analysis. The strain response, local deformation and the accumulation of plasticity of the bridge with and without unrepaired seismic damage were compared. Moreover, the effect of earthquake sequence on crack initiation caused by low-cycle fatigue of the steel bridge was investigated. The results show that seismic damage has little impact on the overall structural displacement response during the aftershock. The residual local deformation, strain response and the cumulative equivalent plastic strain are affected to some extent by the unrepaired damage. Low-cycle fatigue of the steel arch bridge is not induced by the earthquake sequences. Damage indexes of low-cycle fatigue predicted based on different theories are not exactly the same.

가금 기능유전체 연구를 위한 메추리 모델의 활용 (Application of Quail Model for Studying the Poultry Functional Genomics)

  • 신상수
    • 한국가금학회지
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    • 제44권2호
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    • pp.103-111
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    • 2017
  • The quail (Coturnix japonica) has been used as a model animal in many research fields and its application is still expanding in other fields. Compared to the chicken, the quail is quicker to reach sexually maturity, has short generation intervals, is easy to handle, requires less space and feed, and is sturdy. In addition, it produces many eggs and the research tools developed for chicken can be applied directly to quail or with some modifications. Due to recent advances in next-generation sequencing, abundant sequence data for the quail genome and transcripts have been generated. These sequence data are valuable sources for studying functional genomics using quail, which is one of the model animal used to investigate gene function and networks. Although there are some obstacles to be removed, the quail is the best optimized model to study the functional genomics of poultry. In many research fields, functional genomics study using the quail model will provide the best opportunity to understand the phenomena and principles of life. We review why, among many other birds, the quail is the best model for studying poultry functional genomics.

비선형 줌-렌즈 왜곡 모델을 이용한 비디오 영상에서의 줌-렌즈 왜곡 보정 (Zoom Lens Distortion Correction Of Video Sequence Using Nonlinear Zoom Lens Distortion Model)

  • 김대현;신형철;오주현;남승진;손광훈
    • 방송공학회논문지
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    • 제14권3호
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    • pp.299-310
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    • 2009
  • 본 논문은 줌-렌즈로 취득한 비디오 영상에 대해서 줌-렌즈의 왜곡을 자동으로 보상할 수 있는 새로운 방법을 제안하였다. 먼저, 초점거리의 증가에 따라 렌즈의 왜곡 계수가 비선형적으로 단조 감소하는 특징으로부터 초점거리와 렌즈 왜곡 계수로 표현되는 비선형 줌-렌즈 왜곡 모델을 정의하였다. 그리고 취득한 비디오 영상으로부터 몇 장의 샘플 영상을 선정하고, 이 샘플영상에 대한 초점거리와 렌즈 왜곡 계수는 기존의 방법들을 이용하여 측정하였다. 이렇게 측정한 초점거리와 렌즈 왜곡 계수들로 부터 줌-렌즈 왜곡 모델을 최적화 시켰다. 최적화된 줌-렌즈 왜곡 모델은 각 비디오 영상의 초점거리를 입력으로 하여 렌즈 왜곡계수를 자동으로 계산할 수 있다. 본 논문에서 제안한 방법은 다양한 실사 영상과 비디오 영상에 적용하여 그 성능을 검증하였으며, 화질의 열화 없이 영상의 왜곡을 보상할 수 있었다.

방사성 우주기원 동위원소를 이용한 티벳고원에서 가장 오래된 제4기(?) 빙성퇴적물인 Bunthang sequence의 절대 연대측정과 이의 고환경 및 지반운동에 대한 의미 (Absolute Age Determination of One of the Oldest Quaternary(?) Glacial Deposit (Bunthang Sequence) in the Tibetan Plateau Using Radioactive Decay of Cosmogonic $^{10}Be$ and $^{26}Al$, the Central Kavakoram, Pakistan: Implication for Paleoenvironment and Tectonics)

  • 성영배
    • 대한지리학회지
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    • 제42권2호
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    • pp.165-176
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    • 2007
  • 티벳고원의 서쪽, 중부 카라코람의 인더스 강이 지나는 Skardu 근처에서 발견된 약 1.3km의 두께를 보이는 Bunthang 시퀀스의 절대 연대측정을 우주 기원 동위원소인 $^{10}Be$$^{26}Al$의 비를 이용해서 측정했으며 약 2백 65만년전에 급격하게 퇴적된 것으로 확인되었다. 이러한 퇴적시기는 지금까지 발견된 가장 오래된 직접적인 빙하활동의 증거로서 이전의 고지자기 연구와도 일치한다. Bunthang 시퀀스는 아래에서부터 빙퇴석, 호성 퇴적물, 하천 퇴적물 그리고 다시 호성 퇴적물로 이루어지며 어떠한 단층운동의 증거도 발견되지 않는 점으로 미루어 볼 때 분지의 생성은 빙하의 하방침식에 의해서 만들어졌으며 빙하의 후퇴와 더불어 proglacial과 paraglacial 프로세스에 의해서 생성된 것으로 판단된다. 이 지역에 있어서 신생대의 활발한 지반 활동은 인더스 강의 구배를 변형시킴으로써 연구지역과 같은 국지적인 호소퇴적층의 활발한 퇴적을 용이하게 하였으며 또한 지반운동과 빙하의 침식에 의한 사면의 불안정성은 이러한 국지적 퇴적 작용을 더욱 촉발시켰을 것으로 판단된다. 이전의 연구와 본 연구의 결과로써 지난 제4기 동안 빙하의 활동이 약해진 것으로 보건데 지난 마지막 빙기 최성기를 정점으로 티벳고원에 커다란 빙상이 존재했다는 가설은 틀린 것으로 보인다. 이 지역에서 제4기 동안의 빙하 활동의 축소는 희말라야 산맥과 카라코람 산맥 중심의 급격한 융기로 인해 Indian monsoon의 유입이 줄어든 것에서 기인한 것으로 추측된다.

Linear Eddy Model을 이용한 스칼라의 혼합특성 해석 (Analysis for Scalar Mixing Characteristics using Linear Eddy Model)

  • 김후중;류연숙;김용모
    • 한국분무공학회지
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    • 제11권1호
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    • pp.1-6
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    • 2006
  • The present study is focused on the small scale turbulent mixing processes in the scalar Held. In order to deal with molecular mixing in turbulent flow, the linear eddy model is addressed. In each realization, the molecular mixing term is implemented deterministically, and turbulent stirring is represented by a sequence of instantaneous, statistically independent rearrangement event called by triplet map. The LEM approach is applied with relatively simple conditions. The characteristics of scalar mixing and PDF profiles are addressed in detail.

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공정순서에 기초한 생산셀 설계를 위한 유전 알고리즘 접근 (A Genetic Algorithm for Manufacturing Cell Design Based on Operation Sequence)

  • 문치웅;김재균
    • 한국경영과학회지
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    • 제23권3호
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    • pp.123-133
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    • 1998
  • A cell design model based on operation sequence is proposed for maximizing the total parts flow within cells considering the data of Process plans for parts, Production volume, and cell size. A relationship between machines is calculated on the basis of the process plans for parts obtained from process plan sheets. Then the machines are classified into machine cells using the relationship. The model is formulated as a 0-1 integer programming and a genetic algorithm approach is developed to solve the model. The developed approach is tested and Proved using actual industrial data. Experimental results indicate that the approach is appropriate for large-size cell design problems efficiently.

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항공교통관제사의 항공기 합류순서결정에 대한 확률적 예측모형 개발 (Probabilistic Model for Air Traffic Controller Sequencing Strategy)

  • 김민지;홍성권;이금진
    • 한국항공운항학회지
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    • 제22권3호
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    • pp.8-14
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    • 2014
  • Arrival management is a tool which provides efficient flow of traffic and reduces ATC workload by determining aircraft's sequence and schedules while they are in cruise phase. As a decision support tool, arrival management should advise on air traffic control service based on the understanding of human factor of its user, air traffic controller. This paper proposed a prediction model for air traffic controller sequencing strategy by analyzing the historical trajectory data. Statistical analysis is used to find how air traffic controller decides the sequence of aircraft based on the speed difference and the airspace entering time difference of aircraft. Logistic regression was applied for the proposed model and its performance was demonstrated through the comparison of the real operational data.

Multi-layered attentional peephole convolutional LSTM for abstractive text summarization

  • Rahman, Md. Motiur;Siddiqui, Fazlul Hasan
    • ETRI Journal
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    • 제43권2호
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    • pp.288-298
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    • 2021
  • Abstractive text summarization is a process of making a summary of a given text by paraphrasing the facts of the text while keeping the meaning intact. The manmade summary generation process is laborious and time-consuming. We present here a summary generation model that is based on multilayered attentional peephole convolutional long short-term memory (MAPCoL; LSTM) in order to extract abstractive summaries of large text in an automated manner. We added the concept of attention in a peephole convolutional LSTM to improve the overall quality of a summary by giving weights to important parts of the source text during training. We evaluated the performance with regard to semantic coherence of our MAPCoL model over a popular dataset named CNN/Daily Mail, and found that MAPCoL outperformed other traditional LSTM-based models. We found improvements in the performance of MAPCoL in different internal settings when compared to state-of-the-art models of abstractive text summarization.

Measurement and Simulation of Wide-area Frequency in US Eastern Interconnected Power System

  • Kook, Kyung Soo;Liu, Yilu
    • Journal of Electrical Engineering and Technology
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    • 제8권3호
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    • pp.472-477
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    • 2013
  • An internet-based, real-time GPS synchronized wide-area power system frequency monitoring network(FNET) has been monitoring wide-area power system frequency in continuous time in the United States. This paper analyzes the FNET measurement to the verified disturbances in the US eastern interconnected power system and simulates it using the dynamic system model. By comparing the frequency measurements with its simulation results to the same disturbances in detail, this paper finds that the sequence of monitoring points to detect the frequency fluctuation caused by the disturbances is matched well in the measured data and the simulation results. The similarity comparison index is also proposed to quantify the similarity of the compared cases. The dynamic model based simulation result is expected to compensate for the lack of FNET measurement in its applications.