• Title/Summary/Keyword: sequence-to-sequence model

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Analyses of Expressed Sequence Tags from Chironomus riparius Using Pyrosequencing : Molecular Ecotoxicology Perspective

  • Nair, Prakash M. Gopalakrishnan;Park, Sun-Young;Choi, Jin-Hee
    • Environmental Analysis Health and Toxicology
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    • v.26
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    • pp.10.1-10.7
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    • 2011
  • Objects: Chironomus riparius, a non-biting midge (Chironomidae, Diptera), is extensively used as a model organism in aquatic ecotoxicological studies, and considering the potential of C. riparius larvae as a bio-monitoring species, little is known about its genome sequences. This study reports the results of an Expressed Sequence Tags (ESTs) sequencing project conducted on C. riparius larvae using 454 pyrosequencing. Method: To gain a better understanding of C. riparius transcriptome, we generated ESTs database of C.ripairus using pyrosequencing method. Results: Sequencing runs, using normalized cDNA collections from fourth instar larvae, yielded 20,020 expressed sequence tags, which were assembled into 8,565 contigs and 11,455 singletons. Sequence analysis was performed by BlastX search against the National Center for Biotechnology Information (NCBI) nucleotide (nr) and uniprot protein database. Based on the gene ontology classifications, 24% (E-value${\leq}1^{-5}$) of the sequences had known gene functions, 24% had unknown functions and 52% of sequences did not match any known sequences in the existing database. Sequence comparison revealed 81% of the genes have homologous genes among other insects belonging to the order Diptera providing tools for comparative genome analyses. Targeted searches using these annotations identified genes associated with essential metabolic pathways, signaling pathways, detoxification of toxic metabolites and stress response genes of ecotoxicological interest. Conclusions: The results obtained from this study would eventually make ecotoxicogenomics possible in a truly environmentally relevant species, such as, C. riparius.

Residual seismic performance of steel bridges under earthquake sequence

  • Tang, Zhanzhan;Xie, Xu;Wang, Tong
    • Earthquakes and Structures
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    • v.11 no.4
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    • pp.649-664
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    • 2016
  • A seismic damaged bridge may be hit again by a strong aftershock or another earthquake in a short interval before the repair work has been done. However, discussions about the impact of the unrepaired damages on the residual earthquake resistance of a steel bridge are very scarce at present. In this paper, nonlinear time-history analysis of a steel arch bridge was performed using multi-scale hybrid model. Two strong historical records of main shock-aftershock sequences were taken as the input ground motions during the dynamic analysis. The strain response, local deformation and the accumulation of plasticity of the bridge with and without unrepaired seismic damage were compared. Moreover, the effect of earthquake sequence on crack initiation caused by low-cycle fatigue of the steel bridge was investigated. The results show that seismic damage has little impact on the overall structural displacement response during the aftershock. The residual local deformation, strain response and the cumulative equivalent plastic strain are affected to some extent by the unrepaired damage. Low-cycle fatigue of the steel arch bridge is not induced by the earthquake sequences. Damage indexes of low-cycle fatigue predicted based on different theories are not exactly the same.

Application of Quail Model for Studying the Poultry Functional Genomics (가금 기능유전체 연구를 위한 메추리 모델의 활용)

  • Shin, Sangsu
    • Korean Journal of Poultry Science
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    • v.44 no.2
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    • pp.103-111
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    • 2017
  • The quail (Coturnix japonica) has been used as a model animal in many research fields and its application is still expanding in other fields. Compared to the chicken, the quail is quicker to reach sexually maturity, has short generation intervals, is easy to handle, requires less space and feed, and is sturdy. In addition, it produces many eggs and the research tools developed for chicken can be applied directly to quail or with some modifications. Due to recent advances in next-generation sequencing, abundant sequence data for the quail genome and transcripts have been generated. These sequence data are valuable sources for studying functional genomics using quail, which is one of the model animal used to investigate gene function and networks. Although there are some obstacles to be removed, the quail is the best optimized model to study the functional genomics of poultry. In many research fields, functional genomics study using the quail model will provide the best opportunity to understand the phenomena and principles of life. We review why, among many other birds, the quail is the best model for studying poultry functional genomics.

Zoom Lens Distortion Correction Of Video Sequence Using Nonlinear Zoom Lens Distortion Model (비선형 줌-렌즈 왜곡 모델을 이용한 비디오 영상에서의 줌-렌즈 왜곡 보정)

  • Kim, Dae-Hyun;Shin, Hyoung-Chul;Oh, Ju-Hyun;Nam, Seung-Jin;Sohn, Kwang-Hoon
    • Journal of Broadcast Engineering
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    • v.14 no.3
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    • pp.299-310
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    • 2009
  • In this paper, we proposed a new method to correct the zoom lens distortion for the video sequence captured by the zoom lens. First, we defined the nonlinear zoom lens distortion model which is represented by the focal length and the lens distortion using the characteristic that lens distortion parameters are nonlinearly and monotonically changed while the focal length is increased. Then, we chose some sample images from the video sequence and estimated a focal length and a lens distortion parameter for each sample image. Using these estimated parameters, we were able to optimize the zoom lens distortion model. Once the zoom lens distortion model was obtained, lens distortion parameters of other images were able to be computed as their focal lengths were input. The proposed method has been made experiments with many real images and videos. As a result, accurate distortion parameters were estimated from the zoom lens distortion model and distorted images were well corrected without any visual artifacts.

Absolute Age Determination of One of the Oldest Quaternary(?) Glacial Deposit (Bunthang Sequence) in the Tibetan Plateau Using Radioactive Decay of Cosmogonic $^{10}Be$ and $^{26}Al$, the Central Kavakoram, Pakistan: Implication for Paleoenvironment and Tectonics (방사성 우주기원 동위원소를 이용한 티벳고원에서 가장 오래된 제4기(?) 빙성퇴적물인 Bunthang sequence의 절대 연대측정과 이의 고환경 및 지반운동에 대한 의미)

  • Seong, Yeong-Bae
    • Journal of the Korean Geographical Society
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    • v.42 no.2 s.119
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    • pp.165-176
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    • 2007
  • Absolute age of the deposition of 1.3 km-thick Bunthang sequence within the Skardu intermontane basin of the Central Karakoram was determined using radioactive decay of cosmogonic $^{10}Be$ and $^{26}Al$ burial dating. The Bunthang sequence deposited around 2.65 Ma, which is the oldest glaciation in the region. The timing of deposition of the Bunthang sequence is consistent with the previous suggestion that the basin filling took place between Brunhess and Matuyama chrons. Four major sedimentary facies interfinger within the Bunthang sequence: glacial diamict, lacustrine, fluvial and lacustrine facies upward. This sedimentary distinctiveness and the lack of evidence on the faults for alternative pull-apart basin model around the Bunthang sequence, suggest that the depressional basin was formed by deep subglacial erosion during the exrtensive Bunthang Glacial Stage and subsequently the sediments underlain by basal diamict, was quickly deposited by preglacial and paraglacial processes. Temporary ponding of the Indus River due to tectonic uplift in the downstream or blockage by mass movements might make the basin filing more possible. The hypothesis that the single ice sheet developed on the Tibetan Plateau during the global last glacial cycle should be refuted by the existence of the older extensive Bunthang glacier Furthermore, the extensive glaciation during the early Quaternary (and thus progressive decrease in extent with time) suggests that there may have been significant uplift of the Pamir to the west and Himalaya to the south, which would have reduced the penetration of westerlies and Indian summer monsoon and hence moisture supply to the region.

Analysis for Scalar Mixing Characteristics using Linear Eddy Model (Linear Eddy Model을 이용한 스칼라의 혼합특성 해석)

  • Kim, H.J.;Ryu, L.S.;Kim, Y.M.
    • Journal of ILASS-Korea
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    • v.11 no.1
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    • pp.1-6
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    • 2006
  • The present study is focused on the small scale turbulent mixing processes in the scalar Held. In order to deal with molecular mixing in turbulent flow, the linear eddy model is addressed. In each realization, the molecular mixing term is implemented deterministically, and turbulent stirring is represented by a sequence of instantaneous, statistically independent rearrangement event called by triplet map. The LEM approach is applied with relatively simple conditions. The characteristics of scalar mixing and PDF profiles are addressed in detail.

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A Genetic Algorithm for Manufacturing Cell Design Based on Operation Sequence (공정순서에 기초한 생산셀 설계를 위한 유전 알고리즘 접근)

  • 문치웅;김재균
    • Journal of the Korean Operations Research and Management Science Society
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    • v.23 no.3
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    • pp.123-133
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    • 1998
  • A cell design model based on operation sequence is proposed for maximizing the total parts flow within cells considering the data of Process plans for parts, Production volume, and cell size. A relationship between machines is calculated on the basis of the process plans for parts obtained from process plan sheets. Then the machines are classified into machine cells using the relationship. The model is formulated as a 0-1 integer programming and a genetic algorithm approach is developed to solve the model. The developed approach is tested and Proved using actual industrial data. Experimental results indicate that the approach is appropriate for large-size cell design problems efficiently.

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Probabilistic Model for Air Traffic Controller Sequencing Strategy (항공교통관제사의 항공기 합류순서결정에 대한 확률적 예측모형 개발)

  • Kim, Minji;Hong, Sungkwon;Lee, Keumjin
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.22 no.3
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    • pp.8-14
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    • 2014
  • Arrival management is a tool which provides efficient flow of traffic and reduces ATC workload by determining aircraft's sequence and schedules while they are in cruise phase. As a decision support tool, arrival management should advise on air traffic control service based on the understanding of human factor of its user, air traffic controller. This paper proposed a prediction model for air traffic controller sequencing strategy by analyzing the historical trajectory data. Statistical analysis is used to find how air traffic controller decides the sequence of aircraft based on the speed difference and the airspace entering time difference of aircraft. Logistic regression was applied for the proposed model and its performance was demonstrated through the comparison of the real operational data.

Multi-layered attentional peephole convolutional LSTM for abstractive text summarization

  • Rahman, Md. Motiur;Siddiqui, Fazlul Hasan
    • ETRI Journal
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    • v.43 no.2
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    • pp.288-298
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    • 2021
  • Abstractive text summarization is a process of making a summary of a given text by paraphrasing the facts of the text while keeping the meaning intact. The manmade summary generation process is laborious and time-consuming. We present here a summary generation model that is based on multilayered attentional peephole convolutional long short-term memory (MAPCoL; LSTM) in order to extract abstractive summaries of large text in an automated manner. We added the concept of attention in a peephole convolutional LSTM to improve the overall quality of a summary by giving weights to important parts of the source text during training. We evaluated the performance with regard to semantic coherence of our MAPCoL model over a popular dataset named CNN/Daily Mail, and found that MAPCoL outperformed other traditional LSTM-based models. We found improvements in the performance of MAPCoL in different internal settings when compared to state-of-the-art models of abstractive text summarization.

Measurement and Simulation of Wide-area Frequency in US Eastern Interconnected Power System

  • Kook, Kyung Soo;Liu, Yilu
    • Journal of Electrical Engineering and Technology
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    • v.8 no.3
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    • pp.472-477
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    • 2013
  • An internet-based, real-time GPS synchronized wide-area power system frequency monitoring network(FNET) has been monitoring wide-area power system frequency in continuous time in the United States. This paper analyzes the FNET measurement to the verified disturbances in the US eastern interconnected power system and simulates it using the dynamic system model. By comparing the frequency measurements with its simulation results to the same disturbances in detail, this paper finds that the sequence of monitoring points to detect the frequency fluctuation caused by the disturbances is matched well in the measured data and the simulation results. The similarity comparison index is also proposed to quantify the similarity of the compared cases. The dynamic model based simulation result is expected to compensate for the lack of FNET measurement in its applications.