• Journal of Korean Library and Information Science Society
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• v.52 no.1
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• pp.229-254
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• 2021

The purpose of this study is to construct contents of elementary and secondary education which will be included in the information literacy education and to obtain basic information and implications necessary for developing new textbooks. For this study, three types of previously developed textbooks for information literacy education were analyzed, and curriculum content structure, and textbook structure of the draft version of the textbook 'Media and Information Life' developed in 2019-2020 were analyzed. The analysis results are as follows. the information literacy education textbook applied the information problem solving process model and contained the contents of print, and digital media and the media literacy necessary for democratic citizens, but it was necessary to add the types of libraries and media in sequence. Second, library, media, information, and reading literacy were major learning elements that made up the contents of the information literacy curriculum. Third, the "media and information life" textbook needed to present subject competencies, generalized knowledge, content system, and achievement standards in accordance with the system of the 2015 revised curriculum. In addition, social discussion was needed to derive the name of the information literacy curriculum.

• International Journal of Oral Biology
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• v.45 no.4
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• pp.211-217
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• 2020

Molecular mimicry is the most common mechanism that breaches self-tolerance. We previously identified autoantibodies to aquaporin-5 (AQP5) in the sera of patients with Sjögren's syndrome and found that the aquaporin of Prevotella melaninogenica (PmAqp), an oral commensal, is highly homologous to human AQP5. This study aimed to test whether PmAqp can induce anti-AQP5 autoantibodies via molecular mimicry. From the amino acid sequence of PmAqp, an immunizing peptide; i.e., PmE-L, was designed, which contained both the B cell epitope "E" and T cell epitope. C57BL/6 and BALB/c mice were subcutaneously immunized with linear or cyclic forms of PmE-L emulsified in incomplete Freund's adjuvant. The concentrations of the antibodies in sera were measured using enzyme-linked immunosorbent assays. Both linear and cyclic PmE-L induced high levels of antibodies against not only the immunized peptides but also autoantibodies against AQP5E and antibodies against PmE, a Pm homolog of AQP5E. In C57BL/6 mice; however, the cyclic form of PmE-L was more efficient than the linear form in inducing autoantibodies against AQP5E that contained a cyclic epitope. The levels of anti-PmE antibodies and anti-AQP5E autoantibodies showed a strong positive correlation (r = 0.95, p < 0.0005), suggesting molecular mimicry. Collectively, the mice produced anti-AQP5E autoantibodies in response to a PmAqp-derived peptide. This model proved to be useful for studying the mechanisms of autoantibody production by molecular mimicry.

• Mycobiology
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• v.49 no.6
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• pp.582-588
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• 2021

The interaction of mating pheromone and pheromone receptor from the B mating-type locus is the first step in the activation of the mushroom mating signal transduction pathway. The B mating-type locus of Lentinula edodes is composed of Bα and Bβ subloci, each of which contains genes for mating pheromone and pheromone receptor. Allelic variations in both subloci generate multiple B mating-types through which L. edodes maintains genetic diversity. In addition to the B mating-type locus, our genomic sequence analysis revealed the presence of a novel chromosomal locus 43.3 kb away from the B mating-type locus, containing genes for a pair of mating pheromones (PHBN1 and PHBN2) and a pheromone receptor (RCBN). The new locus (Bα-N) was homologous to the Bα sublocus, but unlike the multiallelic Bα sublocus, it was highly conserved across the wild and cultivated strains. The interactions of RcbN with various mating pheromones from the B and Bα-N mating-type loci were investigated using yeast model that replaced endogenous yeast mating pheromone receptor STE2 with RCBN. The yeast mating signal transduction pathway was only activated in the presence of PHBN1 or PHBN2 in the RcbN producing yeast, indicating that RcbN interacts with self-pheromones (PHBN1 and PHBN2), not with pheromones from the B mating-type locus. The biological function of the Bα-N locus was suggested to control the expression of A mating-type genes, as evidenced by the increased expression of two A-genes HD1 and HD2 upon the treatment of synthetic PHBN1 and PHBN2 peptides to the monokaryotic strain of L. edodes.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.4A
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• pp.795-808
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• 2006

In this paper, an analytical method which can predict the occurrence of plastic shrinkage cracking on concrete slabs with sequential placement is proposed on the basis of the numerical model introduced in the previous study. The influence of many design variables on plastic shrinkage cracking such as the number of layers and the time interval between layers is quantitatively analyzed through parametric studies using the analytical method. In advance, two equations are introduced to take into account the effect of sequential placement on the plastic shrinkage cracking of concrete slab; The first one is to calculate the time at which the surface of concrete slab begins to dry, and the second one is to determine the critical time interval to prevent the surface drying of previously placed concrete layers. The timing of curing and the sequence of concrete placement, which are important for the prevention of plastic shrinkage cracking, can be effectively planned using the introduced both equations without any rigorous analysis.

• The Plant Pathology Journal
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• v.40 no.1
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• pp.59-72
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• 2024

A comprehensive survey of mungbean-growing areas was conducted to observe leaf spot disease caused by Alternaria alternata. Alternaria leaf spot symptoms were observed on the leaves. Diversity of 50 genotypes of mungbean was assessed against A. alternata and data on pathological traits was subjected to cluster analysis. The results showed that genotypes of mungbean were grouped into four clusters based on resistance parameters under the influence of disease. The principal component biplot demonstrated that all the disease-related parameters (% disease incidence, % disease intensity, lesion area, and % of infection) were strongly correlated with each other. Alt a 1 gene that is precisely found in Alternaria species and is responsible for virulence and pathogenicity. Alt a 1 gene was amplified using gene specific primers. The isolated pathogen produced similar symptoms when inoculated on mungbean and tobacco. The sequence analysis of the internal transcribed spacer (ITS) region, a 600 bp fragment amplified using specific primers, ITS1 and ITS2 showed 100% identity with A. alternata. Potato virus X (PVX) -based silencing vector expressing Alt a 1 gene was constructed to control this pathogen through RNA interference in tobacco. Out of 50 inoculated plants, 9 showed delayed onset of disease. Furthermore, to confirm our findings at molecular level semi-quantitative reverse transcriptase polymerase chain reaction was used. Both phenotypic and molecular investigation indicated that RNAi induced through the VIGS vector was efficacious in resisting the pathogen in the model host, Tobacco (Nicotiana tabacum). To the best of our knowledge, this study has been reported for the first time.

• Journal of KIISE:Software and Applications
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• v.33 no.11
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• pp.986-998
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• 2006

There has been an increasing necessity of Semantic Web-based metadata that helps computers efficiently understand and manage an information increased with the growth of Internet. However, it seems inevitable to face some semantically ambiguous information when metadata is generated. Therefore, we need a solution to this problem. This paper proposes a new method for automated metadata generation with the help of a concept of class, in which some ambiguous words imbedded in information such as documents are semantically more related to others, by using probability model of consequent words. We considers ambiguities among defined concepts in ontology and uses the Hidden Markov Model to be aware of part of a named entity. First of all, we constrict a Markov Models a better understanding of the named entity of each class defined in ontology. Next, we generate the appropriate context from a text to understand the meaning of a semantically ambiguous word and solve the problem of ambiguities during generating metadata by searching the optimized the Markov Model corresponding to the sequence of words included in the context. We experiment with seven semantically ambiguous words that are extracted from computer science thesis. The experimental result demonstrates successful performance, the accuracy improved by about 18%, compared with SemTag, which has been known as an effective application for assigning a specific meaning to an ambiguous word based on its context.

• Journal of Radiation Protection and Research
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• v.40 no.4
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• pp.216-222
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• 2015

Facilities processing raw materials containing naturally occurring radioactive materials (NORM) may give rise to enhanced radiation dose to workers due to chronic inhalation of airborne particulates. Internal radiation dose due to particulate inhalation varies depending on particulate properties, including size, shape, density, and absorption type. The objective of the present study was to assess inhalation dose sensitivity to physicochemical properties of airborne particulates. Committed effective doses to workers resulting from inhalation of airborne particulates were calculated based on International Commission on Radiological Protection 66 human respiratory tract model. Inhalation dose generally increased with decreasing particulate size. Committed effective doses due to inhalation of $0.01{\mu}m$ sized particulates were higher than doses due to $100{\mu}m$ sized particulates by factors of about 100 and 50 for $^{238}U$ and $^{230}Th$, respectively. Inhalation dose increased with decreasing shape factor. Shape factors of 1 and 2 resulted in dose difference by about 18 %. Inhalation dose increased with particulate mass density. Particulate mass densities of $11g{\cdot}cm^{-3}$ and $0.7g{\cdot}cm^{-3}$ resulted in dose difference by about 60 %. For $^{238}U$, inhalation doses were higher for absorption type of S, M, and F in that sequence. Committed effective dose for absorption type S of $^{238}U$ was about 9 times higher than dose for absorption F. For $^{230}Th$, inhalation doses were higher for absorption type of F, M, and S in that sequence. Committed effective dose for absorption type F of $^{230}Th$ was about 16 times higher than dose for absorption S. Consequently, use of default values for particulate properties without consideration of site specific physiochemical properties may potentially skew radiation dose estimates to unrealistic values up to 1-2 orders of magnitude. For this reason, it is highly recommended to consider site specific working materials and conditions and use the site specific particulate properties to accurately access radiation dose to workers at NORM processing facilities.

• Journal of Korea Water Resources Association
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• v.53 no.7
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• pp.493-505
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• 2020

The rainfall-runoff model has been generally adopted to obtain a consistent runoff sequence with the use of the long-term ground-gauged based precipitation data. The Thiessen polygon is a commonly applied approach for estimating the mean areal rainfall from the ground-gauged precipitation by assigning weight based on the relative areas delineated by a polygon. However, spatial bias is likely to increase due to a sparse network of the rain gauge. This study aims to generate continuous runoff sequences with the mean areal rainfall obtained from radar rainfall estimates through a PRMS rainfall-runoff model. Here, the systematic error of radar rainfall is corrected by applying the G/R Ratio. The results showed that the estimated runoff using the corrected radar rainfall estimates are largely similar and comparable to that of the Thiessen. More importantly, one can expect that the mean areal rainfall obtained from the radar rainfall estimates are more desirable than that of the ground in terms of representing rainfall patterns in space, which in turn leads to significant improvement in the estimation of runoff.

• Journal of Intelligence and Information Systems
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• v.29 no.2
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• pp.323-338
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• 2023

TV advertising with deep analysis of watching pattern of audiences is important to set-top box audience targeting. Applying session-based recommendation model(SBR) to internet commercial, or recommendation based on searching history of user showed its effectiveness in previous studies, but applying SBR to the TV advertising was difficult in South Korea due to data unavailabilities. Also, traditional SBR has limitations for dealing with user preferences, especially in data with user identification information. To tackle with these problems, we first obtain set-top box data from three major broadcasting companies in South Korea(SKB, KT, LGU+) through collaboration with Korea Broadcast Advertising Corporation(KOBACO), and this data contains of watching sequence of 4,847 anonymized users for 6 month respectively. Second, we develop personalized session-based recommendation model to deal with hierarchical data of user-session-item. Experiments conducted on set-top box audience dataset and two other public dataset for validation. In result, our proposed model outperformed baseline model in some criteria.

• Economic and Environmental Geology
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• v.28 no.6
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• pp.599-612
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• 1995

Some REE ore deposits are located in the middle part the of Korean peninsula. Geotectonically, the REE ore deposits situated on the Kyemyeongsan Formation of northern margin of the Okcheon geosynclinal belt and in the transitional zone between Kyeonggi massif and the Okcheon belt, with a deep-seated fracture separating the two tectonic units. The Kyemyeongsan Formation are different in lithology and metamorphic grade from the Gyeonggi massif and the Okcheon super group. The sequence of Kyemyeongsan Formation is dominantly composed of acidic metavolcanic and volcaniclastic rocks associated with alkaline igneous rocks which are related to volcano-plutonism. The REE ore deposits contain mainly Ce-La, Ta-Nb, Y, Y-Nd and Nd-Th group minerals. More than 15 RE and REE minerals have been found in the deposits, such as allanite, fergusonite, thorite bestnaesite, euxenite, polyclase, monazite, columbite, (Nb)-rutile, okanoganite, sphene, zircon, illmenite and some other unknown minerals. According to the characteristics of the mineral association, the REE ore deposits may be divided into 4 ore types; Zircon-REE, allanite-REE, feldspar-REE and fluorite-REE type. The Sm-Nd isochron age of the REE ore is 330 Ma, and the Sm-Nd model age is 1.11 Ga with ${\varepsilon}_{Nd(t)}$ being - 2.9. This data suggest that the REE ore deposit was formed in the early Carboniferous, and the ore-forming material came from the mantle. The REE ores show distinct light REE enrichment with strong negative Eu anomaly. The REE patterns of schistose rocks from Kyemyeongsan Formation are similar to felsic volcanics from rifts or back arc basins in or near continental crust. The genesis of the REE ore deposit is quite complicated. Different geologic processes are displayed in the studied area; sedimentation, volcanic activity, metamorphism and hydrothermal replacement. Alkali granite has suffered extensive post-magmatic metasomatism of a high temperature to produce alkali metasomatites. Geochemical charateristics show that metasomatism of alkaline fluid was probably the dominant ore-forming process in Chungju district.