• Journal of Breast Cancer
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• v.21 no.4
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• pp.442-446
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• 2018

Purpose: The definition of nodal pathologic complete response (pCR) after a neoadjuvant chemotherapy (NAC) just included the evaluation of axillary lymph node (ALN) without internal mammary lymph node. This study aimed to evaluate the feasibility of internal mammary-sentinel lymph node biopsy (IM-SLNB) in patients with breast cancer who underwent NAC. Methods: From November 2011 to 2017, 179 patients with primary breast cancer who underwent operation after NAC were included in this study. All patients received radiotracer injection with modified injection technology. IM-SLNB would be performed on patients with internal mammary sentinel lymph node (IMSLN) visualization. Results: Among the 158 patients with cN+ disease, the rate of nodal pCR was 36.1% (57/158). Among the 179 patients, the visualization rate of IMSLN was 31.8% (57/179) and was 12.3% (7/57) and 87.7% (50/57) among those with $cN_0$ and cN+ disease, respectively. Furthermore, the detection rate of IMSLN was 31.3% (56/179). The success rate of IM-SLNB was 98.2% (56/57). The IMSLN metastasis rate was 7.1% (4/56), and all of them were accompanied by ALN metastasis. The number of positive ALNs in patients with IMSLN metastasis was 3, 6, 8, and 9. The pathology nodal stage had been changed from $pN_1/pN_2$ to $pN_{3b}$. The pathology stage had been changed from IIA/IIIA to IIIC. Conclusion: Patients with visualization of IMSLN should perform IM-SLNB after NAC, especially for patients with cN+ disease, in order to complete lymph nodal staging. IM-SLNB could further improve the definition of nodal pCR and guide the internal mammary node irradiation.

• The Korean Journal of Nuclear Medicine Technology
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• v.16 no.2
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• pp.62-67
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• 2012

Purpose : At this time, the sentinel lymph node mapping using radioisotope and blue dye is preceded for breast cancer patient's sentinel lymph node biopsy. But all patients were applied the same protocol without consideration of physical specific character like the breast sizes and body mass indexes. The purpose of this study is search the optimized scan time in breast sentinel lymphangiography by observing how much the body mass index and breast size influence speed of lymphatic flow. Materials and Methods : The Object of this study was 100 breast cancer patients(Female, 100 persons, average age $50.34{\pm}10.26$ years old)at Severance hospital from October 2011 to December 2011. They were scanned breast sentinel lymphangiography before operation. This study was performed on Forte dual heads gamma camera (Philips Medical Systems, Nederland B.V.). All patients were intra-dermal injected $^{99m}Tc$-Phytate 18.5 MBq, 0.5 ml. For 80 patients, we have scanned without limitation of scan time until the lymphatic flow from the lymph node since injection. We measured how long the lymphatic flow time between departures from injects site and arrival to lymph node using stopwatch. After we calculated patient's Body mass Index and classified as 4 groups. And we measured patient's breast size and classified 3 groups. The modified breast lymphangiography that changing scan time according to comparison study's result was performed on 20 patients and was estimated. Results : The mean scan time as breast size was A group 2.48 minutes, B group 7.69 minutes, C group 10.43 minutes. The mean scan time as body mass index was under weight 1.35 minutes, normal weight 2.56 minutes, slightly over 5.62 minutes, over weighted 5.62 minutes. The success rate of modified breast lymphangiography was 85%. Conclusion : As the Body mass index became higher and breast size became bigger, the total scan time is increased. Based on the obtained information, we designed modified breast lymphangiography protocol. At the cases applying that protocol, most of sentinel lymph nodes were visualized as lymphatic pool. In conclusion, we found that the more success rate in modified protocol considering physical individuality than study carrying out in the same protocol.

• Korean Journal of Remote Sensing
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• v.37 no.6_1
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• pp.1773-1784
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• 2021

In order to minimize damage to oil spill accidents in the ocean, it is essential to collect a spilled area as soon as possible. Thus satellite-based remote sensing is a powerful source to detect oil spills in the ocean. With the recent rapid increase in the number of available satellites, it has become possible to generate a status report of marine oil spills soon after the accident. In this study, the oil spill area was calculated using various satellite images for the Symphony oil spill accident that occurred off the coast of Qingdao Port, China, on April 27, 2021. In particular, improving the accuracy of oil spill area determination was applied using high-resolution commercial satellite images with a spatial resolution of 2m. Sentinel-1, Sentinel-2, LANDSAT-8, GEO-KOMPSAT-2B (GOCI-II) and Skysat satellite images were collected from April 27 to May 13, but five images were available considering the weather conditions. The spilled oil had spread northeastward, bound for coastal region of China. This trend was confirmed in the Skysat image and also similar to the movement prediction of oil particles from the accident location. From this result, the look-alike patch observed in the north area from the Sentinel-1A (2021.05.01) image was discriminated as a false alarm. Through the survey period, the spilled oil area tends to increase linearly after the accident. This study showed that high-resolution optical satellites can be used to calculate more accurately the distribution area of spilled oil and contribute to establishing efficient response strategies for oil spill accidents.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.sup3
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• pp.317-321
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• 2016

Detection of micrometastasis in sentinel lymph nodes (SLNs) is a very useful tool for appropriate assessment of the clinical stage of disease in breast cancer patients. Early identification of clinically relevant disease could lead to early treatment or staging approaches for breast cancer patient. Micrometastases in SLNs of women with invasive breast cancer are of great significance in this context. In this study we examined SLN biopsies considered to have small numbers of cancerous cells by real time RT-PCR. All of the samples underwent immunohistochemical staining for cytokeratin for confirmation of the presence or absence of micrometastases. BUB1b expression assay of selected patients with and without metastasis showed overexpression in the former, but not in normal breast and lymph node tissue. Our results may be taken into account in the discussion about the merits of routine use of molecular assessment in pathogenetic studies of SLNs.

• Journal of Korea Water Resources Association
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• v.55 no.11
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• pp.913-922
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• 2022

The purpose of this research is to propose the measurement of improving DEM by using the water surface range of SAR image analysis for river corridors and to suggest the construction of satellite-based 3D river spatial information of inaccessible regions such as North Korea. For this research, it has been progressed from the accessible area, watershed of Namgang river, the branch of Nakdonggang river. The satellite image was collected from SAR satellite image data for a year in 2021 which was provided by ESA from Sentinel-1A/B data and extracted from the seasonal water surface area. Ground gauge water level was collected from hourly intervals data by WAMIS. The DEM was improved by analysis of the river altitude of water surface area change by the combination of the ground water level of minimum to maximum water surface area data extracted from SAR image analysis. After the improvement of DEM, the altitude of the river varied that it is defined to comprise more natural form of river DEM than the existing DEM. The correction validation of improvement DEM was necessary in field survey elevation data; however, the correction validation was not progressed due to the absence of the data. Although, the purpose of this research is to provide the improvement of DEM by using the analyzed water surface by existing DEM data and SAR image analysis. After the progression of additional correction validation research, we would plan to examine the application in other places and to progress the additional methodological research to apply in inaccessible and unmeasured area including the North Korea.

• Korean Journal of Remote Sensing
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• v.36 no.6_2
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• pp.1509-1521
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• 2020

Experiments for validation of surface reflectance produced by Korea Multi-Purpose Satellite (KOMPSAT-3A) were conducted using Chinese Baotou (BTCN) data among four sites of the Radical Calibration Network (RadCalNet), a portal that provides spectrophotometric reflectance measurements. The atmosphere reflectance and surface reflectance products were generated using an extension program of an open-source Orfeo ToolBox (OTB), which was redesigned and implemented to extract those reflectance products in batches. Three image data sets of 2016, 2017, and 2018 were taken into account of the two sensor model variability, ver. 1.4 released in 2017 and ver. 1.5 in 2019, such as gain and offset applied to the absolute atmospheric correction. The results of applying these sensor model variables showed that the reflectance products by ver. 1.4 were relatively well-matched with RadCalNet BTCN data, compared to ones by ver. 1.5. On the other hand, the reflectance products obtained from the Landsat-8 by the USGS LaSRC algorithm and Sentinel-2B images using the SNAP Sen2Cor program were used to quantitatively verify the differences in those of KOMPSAT-3A. Based on the RadCalNet BTCN data, the differences between the surface reflectance of KOMPSAT-3A image were shown to be highly consistent with B band as -0.031 to 0.034, G band as -0.001 to 0.055, R band as -0.072 to 0.037, and NIR band as -0.060 to 0.022. The surface reflectance of KOMPSAT-3A also indicated the accuracy level for further applications, compared to those of Landsat-8 and Sentinel-2B images. The results of this study are meaningful in confirming the applicability of Analysis Ready Data (ARD) to the surface reflectance on high-resolution satellites.

• Korean Journal of Remote Sensing
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• v.38 no.6_1
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• pp.1343-1356
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• 2022

Clouds or shadows are the most problematic when monitoring crops using optical satellite images. To reduce this effect, a composite algorithm was used to select the maximum Normalized Difference Vegetation Index (NDVI) for a certain period. This Maximum NDVI Composite (MNC) method reduces the influence of clouds, but since only the maximum NDVI value is used for a certain period, it is difficult to show the phenomenon immediately when the NDVI decreases. As a way to maintain the spectral information of crop as much as possible while minimizing the influence of clouds, a Score-Based Composite (SBC) algorithm was proposed, which is a method of selecting the most suitable pixels by defining various environmental factors and assigning scores to them when compositing. In this study, the Sentinel-2A/B Level 2A reflectance image and cloud, shadow, Aerosol Optical Thickness(AOT), obtainging date, sensor zenith angle provided as additional information were used for the SBC algorithm. As a result of applying the SBC algorithm with a 15-day and a monthly period for Dangjin rice fields and Taebaek highland cabbage fields in 2021, the 15-day period composited data showed faster detailed changes in NDVI than the monthly composited results, except for the rainy season affected by clouds. In certain images, a spatially heterogeneous part is seen due to partial date-by-date differences in the composited NDVI image, which is considered to be due to the inaccuracy of the cloud and shadow information used. In the future, we plan to improve the accuracy of input information and perform quantitative comparison with MNC-based composite algorithm.

• Korean Journal of Remote Sensing
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• v.36 no.5_3
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• pp.1095-1107
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• 2020

Flood monitoring using satellite data has been constrained by obtaining satellite images for flood peak and accurately extracting flooded areas from satellite data. Deep learning is a promising method for satellite image classification, yet the potential of deep learning-based flooded area extraction using SAR data remained uncertain, which has advantages in obtaining data, comparing to optical satellite data. This research explores the performance of SegNet and U-Net on image segmentation by extracting flooded areas in the Khorat basin, Mekong river basin, and Cagayan river basin in Thailand, Laos, and the Philippines from Sentinel-1 A/B satellite data. Results show that Global Accuracy, Mean IoU, and Mean BF Score of SegNet are 0.9847, 0.6016, and 0.6467 respectively, whereas those of U-Net are 0.9937, 0.7022, 0.7125. Visual interpretation shows that the classification accuracy of U-Net is higher than SegNet, but overall processing time of SegNet is around three times faster than that of U-Net. It is anticipated that the results of this research could be used when developing deep learning-based flood monitoring models and presenting fully automated flooded area extraction models.

• Korean Journal of Remote Sensing
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• v.35 no.6_1
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• pp.933-944
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• 2019

This study analyzes the tide deformation of land boundary regions on the east (Region A) and west (Region B) sides of the Ross Ice Shelf in Antarctica using Double-Differential Interferometric Synthetic Aperture Radar (DDInSAR). A total of seven Sentinel-1A SAR images acquired in 2015-2016 were used to estimate the accuracy of tide prediction model and Young's modulus of ice shelf. First, we compared the Ross Sea Height-based Tidal Inverse (Ross_Inv) model, which is a representative tide prediction model for the Antarctic Ross Sea, with the tide deformation of the ice shelf extracted from the DDInSAR image. The accuracy was analyzed as 3.86 cm in the east region of Ross Ice Shelf and it was confirmed that the inverse barometric pressure effect must be corrected in the tide model. However, in the east, it is confirmed that the tide model may be inaccurate because a large error occurs even after correction of the atmospheric effect. In addition, the Young's modulus of the ice was calculated on the basis of the one-dimensional elastic beam model showing the correlation between the width of the hinge zone where the tide strain occurs and the ice thickness. For this purpose, the grounding line is defined as the line where the displacement caused by the tide appears in the DDInSAR image, and the hinge line is defined as the line to have the local maximum/minimum deformation, and the hinge zone as the area between the two lines. According to the one-dimensional elastic beam model assuming a semi-infinite plane, the width of the hinge region is directly proportional to the 0.75 power of the ice thickness. The width of the hinge zone was measured in the area where the ground line and the hinge line were close to the straight line shown in DDInSAR. The linear regression analysis with the 0.75 power of BEDMAP2 ice thickness estimated the Young's modulus of 1.77±0.73 GPa in the east and west of the Ross Ice Shelf. In this way, more accurate Young's modulus can be estimated by accumulating Sentinel-1 images in the future.

• Korean Journal of Remote Sensing
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• v.37 no.5_2
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• pp.1329-1340
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• 2021

The intertidal zone, which is a transitional zone between the ocean and the land, requires continuous monitoring as various changes occur rapidly due to artificial activity and natural disturbance. Monitoring of coastal topography changes using remote sensing method is evaluated to be effective in overcoming the limitations of intertidal zone accessibility and observing long-term topographic changes in intertidal zone. Most of the existing coastal topographic monitoring studies using remote sensing were conducted through high spatial resolution images such as Landsat and Sentinel. This study extracted the waterline using the NDWI from the GOCI-II (Geostationary Ocean Color Satellite-II) data, identified the changes in the intertidal area in Gyeonggi Bay according to various tidal heights, and examined the utility of DEM generation and topography altitude change observation over a short period of time. GOCI-II (249 scenes), Sentinel-2A/B (39 scenes), Landsat 8 OLI (7 scenes) images were obtained around Gyeonggi Bay from October 8, 2020 to August 16, 2021. If generating intertidal area DEM, Sentinel and Landsat images required at least 3 months to 1 year of data collection, but the GOCI-II satellite was able to generate intertidal area DEM in Gyeonggi Bay using only one day of data according to tidal heights, and the topography altitude was also observed through exposure frequency. When observing coastal topography changes using the GOCI-II satellite, it would be a good idea to detect topography changes early through a short cycle and to accurately interpolate and utilize insufficient spatial resolutions using multi-remote sensing data of high resolution. Based on the above results, it is expected that it will be possible to quickly provide information necessary for the latest topographic map and coastal management of the Korean Peninsula by expanding the research area and developing technologies that can be automatically analyzed and detected.