• Imaging Science in Dentistry
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• 제47권3호
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• pp.199-207
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• 2017

Purpose: Evaluation of alveolar bone is important in the diagnosis of dental diseases. The periodontal ligament space is difficult to clearly depict in cone-beam computed tomography images because the reconstruction filter conditions during image processing cause image blurring, resulting in decreased spatial resolution. We examined different reconstruction filters to assess their ability to improve spatial resolution and allow for a clearer visualization of the periodontal ligament space. Materials and Methods: Cone-beam computed tomography projections of 2 skull phantoms were reconstructed using 6 reconstruction conditions and then compared using the Thurstone paired comparison method. Physical evaluations, including the modulation transfer function and the Wiener spectrum, as well as an assessment of space visibility, were undertaken using experimental phantoms. Results: Image reconstruction using a modified Shepp-Logan filter resulted in better sensory, physical, and quantitative evaluations. The reconstruction conditions substantially improved the spatial resolution and visualization of the periodontal ligament space. The difference in sensitivity was obtained by altering the reconstruction filter. Conclusion: Modifying the characteristics of a reconstruction filter can generate significant improvement in assessments of the periodontal ligament space. A high-frequency enhancement filter improves the visualization of thin structures and will be useful when accurate assessment of the periodontal ligament space is necessary.

• Archives of Plastic Surgery
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• 제38권4호
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• pp.494-497
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• 2011

Purpose: Schwannoma, a benign peripheral nerve tumor, is slow-growing, encapsulated neoplasm that originates from the Schwann cell of the nerve sheath. Schwannoma most frequently involves the major nerve. Schwannoma occurring in the superficial radial nerve rare. This is a report of our experience with schwannoma arising from the superficial radial nerve with neurologic symptom. Methods: A 55-year-old woman presented with eight-month history of progressive numbness and paresthesia in dorsum of the thumb and index finger. Physical examination revealed a localized mass on the midforearm. Sonographic examination showed an ovoid, heterogenous, hypoechoic lesion, located eccentrically in related to the superficial radial nerve. The lesion was mobile in the transverse but not in the longitudinal axis of the nerve, which was thought to favour schwannoma rather than neurofibroma. At operation, a $20{\times}15mm$ ovoid, yellowish grey mass was seen arising from the superficial radial nerve. The tumor present as eccentric masses over which the nerve fibers are splayed. Using operating microscope, the tumor was removed, preserving the surrounding nerve. Results: Histology confirmed that the mass was a benign schwannoma. There were no postoperative complications. After two months the patient had no clinically demonstrable sensory deficit. Conclusion: An unsusual case of a schwannoma of the superficial radial nerve is presented. In case with neurologic symptom, prompt surgical decompression must be made to prevent further nerve damage and to restore nerve function early.

• 한국안광학회지
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• 제14권1호
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• pp.81-86
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• 2009

목적: 본 연구는 새롭게 개발한 MYSTERY CIRCLE, Anaglyphs 및 Block string을 이용하여 양안시 기능적, 감각적, 증상 변화에 대해 비교 관찰하고, 훈련방식별 개선효과와 실용 가능성을 알아보고자 하였다. 방법: 대상자는 T안경원의 75명의 시기능 훈련 대상자(남자 40명, 여자 35명)이며 7주(49일)동안 시기능 훈련을 실시하였다. 결과: 모든 훈련방식(MYSTERY CIRCLE, Anaglyphs, Block string)에서 시기능 훈련자의 양안시 개선에 도움이 되었으나, 정상화 성공기준에 포함된 대상자수를 비교한 결과 MYSTERY CIRCLE훈련이 유의수준 0.05에서 다른 훈련방식과 유의한 차이를 보였다. 결론: 본 연구에서 MYSTERY CIRCLE 훈련이 양안시 이상자의 시기능 개선 및 정상화에 우수한 개선효과가 있는 것으로 나타났다.

• 동의생리병리학회지
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• 제25권2호
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• pp.217-226
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• 2011

The aim of this study is to identify central neural pathway of neurons following the projection to the large intestine and Hapgok(LI4) which is Won acupoint of the large intestine meridian of hand-yangmyeong. In this experiment, Bartha's strain of pseudorabies virus was used to trace central localization of neurons related with large intestine and acupoint(LI4) which has been known to be able to regulate intestinal function. The animals were divided into 3 groups: group 1, injected into the large intestine; group 2, injected into the acupoint(LI4); group 3, injected into the acupoint(LI4) after severing the radial, ulnar, median nerve. After four days survival of rats, PRV labeled neurons were identified in the spinal cord and brain by immunohistochemical method. First-order PRV labeled neurons following the projection to large intestine, acupoint(LI4) and acupoint(LI4) after cutting nerve were found in the cervical, thoracic, lumbar and sacral spinal cord. Commonly labeled neurons were labeled in the lumbosacral spinal cord and thoracic spinal cord. They were found in lamina V- X, intermediomedial nucleus and dorsal column area. The area of sensory neurons projecting was L5-S2 spinal ganglia and T12-L1 spinal ganglia, respectively. In the brainstem, the neurons were labeled most evidently and consistently in the nucleus tractus solitarius, area postrema, dorsal motor nucleus of vagus nerve, reticular nucleus, raphe nuclei(obscurus, magnus and pallidus), C3 adrenalin cells, parapyramidal area(lateral paragigantocellular nucleus), locus coeruleus, subcoeruleus nucleus, A5 cell group, periaqueductal gray matter. In the diencephalon, PRV labeled neurons were marked mostly in the arcuate nucleus and median eminence. These results suggest that overlapped CNS locations are related with autonomic nuclei which regulate the functions of large intestine-related organs and it was revealed by tracing PRV labeled neurons projecting large intestine and related acupoint(LI4).

• Archives of Reconstructive Microsurgery
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• 제7권1호
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• pp.35-40
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• 1998

The incidence of brachial plexus injury is increasing because of the development of motor vehicle but the the results of treatment was reported poor due to its complex anatomical structure and changes of function and sensory during the recovery after trauma. But the results of treatment has been improved by the recently introduced high sensitive diagnostic method that can evaluate accurately the site and extent of the injury and treatment method. Restoration of the elbow flexion is the most important goal of treatment after brachial plexus injury and nerve graft, neurotization and muscle transfer were used for methods of treatment. From December 1992 to May 1994, the author performed 6 cases of latissimus dorsi transfer at the same side for the improvement of elbow flexion in the patients of brachial plexus injury. There were 5 cases of male, one case of female and average age was 22 years old. The causes of injury were traffic accident in 3 cases, gun shot injury, falldown and birth injury in each one case and in all cases, the type of injury were upper arm type. The average follow up period were 1 year 5 months ranging from 12 months to 4 years 5 months. In all cases, active elbow flexion was impossible before operation and average muscle power was grade I. We analysed the active range of motion, muscle power and the functional results. At the last follow up, range of active elbow flexion was average $124^{\circ}$ and flexion contracture was average 11 degrees and the average of muscle power was grade IV. In the functional analysis, there were two cases of excellent, three cases of good and 1 case of fair. There was no complications including wound infection, vascular compromise and donor site problem. The results of latissimus dorsi transfer for improvement elbow flexion in the patients of brachial plexus injury is one of the useful mettled for the restoration of elbow flexion.

• 한국콘텐츠학회논문지
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• 제9권6호
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• pp.187-195
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• 2009

본 연구는 흰쥐를 대상으로 좌골신경 압좌 손상 유발 후 경피신경전기자극과 전침자극을 적용하고 진통효과와 기능회복에 미치는 영향을 알아보았다. 실험동물은 경피신경전기자극군을 적용한 TENS군, 전침자극군을 적용한 EA군과 대조군으로 구분하였고, 각각의 군은 전기자극 적용기간에 따라 1일군, 7일군 및 14일군으로 나누었다. 경피신경자극과 전침자극을 적용한 결과, 실험군에서 대조군에 비하여 통각신경활성의 지표로 이용되는 c-fos 발현의 감소, 발도피지연시의 증가, 좌골신경기능지수의 증가를 통해 전기자극이 말초신경 손상에서 통증억제와 기능회복을 증가시키는 것으로 나타났다. 하지만 경피신경전기자극군과 전침자극군간의 유의한 차이는 관찰되지 않았다.

• 한국응용과학기술학회지
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• 제35권4호
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• pp.1472-1479
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• 2018

본 연구는 지속적인 곡예 운동이 여자 체조, 프리스타일 스키어 및 피겨 스케이터 선수의 동적자세 유지 능력에 미치는 영향을 분석하고자 하였다. 이 연구에 참여한 피험자는 운동경력이 4-6년 된 운동선수로서 체조선수 7명, 프리스타일 스키어 선수8명, 피겨 스케이터 7명과 일반 여학생 10명을 통제집단으로 분류하였다. 동적자세의 운동능력을 비교하고자 뉴로컴사의 동적자세측정기를 이용하여 6가지 각 조건에 맞는 이른바, 시각계, 전정계 및 체성감각계가 동원되는 상황을 연출하면서 실험에 임하였다. 자료처리는 일원변량분석을 실시하였고, 사후검증으로는 집단 간의 차이를 보고자 Scheffe로 하였고, 통계학적 유의수준은 .05로 하였다. 연구결과 운동집단 간에는 조건 5에서 프리스타일 선수와 체조선수 간의 유의한 차이가 있었으며, 운동선수 집단과 일반인 여학생 간에는 조건 2, 3, 4, 5, 6에서 유의한 차이가 나타났다. 결론적으로 지속적인 곡예 운동은 평형기관계를 자극하여 동적자세 조절의 향상에 효과가 있는 것으로 사료된다.

• 한국포장학회지
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• 제24권3호
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• pp.113-120
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• 2018

The one-way gas valve developed in this study was designed to prevent the breakage of packages from increased internal pressure, which is a problem in packaged Kimchi, and simultaneously reduce the outflow of the offodor release. The effect of the one-way gas valve on the headspace atmospheric compositions was investigated in the packaging system. The changes of atmospheric compositions and quality factors of Kimchi, such as $CO_2$ accumulation, pH, titratable acidity, and salinity, were measured during a 4-week storage period at $4^{\circ}C$. The Kimchi package with the one-way gas valve dramatically reduced pressure build-up in the pouch by allowing the controlled flow of gas to the atmosphere. In addition, the package design allows the possibility of controlling the gas generated from Kimchi by adjusting the viscosity of the open pressure control oil. The one-way gas valve did not affect the sensory characteristics of Kimchi products during the storage period. Furthermore, the deodorizing capability of the activated carbon contained in the one-way gas valve effectively reduced the off-odor of Kimchi products released along with carbon dioxide. The novel one-way gas valve is considered to be an active packaging system that can solve major problems of expansion and off-odor leakage in the packaging of Kimchi.

• Journal of Microbiology and Biotechnology
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• 제29권10호
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• pp.1522-1542
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• 2019

To adapt to environmental changes and to maintain cellular homeostasis, microorganisms adjust the intracellular concentrations of biochemical compounds, including metal ions; these are essential for the catalytic function of many enzymes in cells, but excessive amounts of essential metals and heavy metals cause cellular damage. Metal-responsive transcriptional regulators play pivotal roles in metal uptake, pumping out, sequestration, and oxidation or reduction to a less toxic status via regulating the expression of the detoxification-related genes. The sensory and regulatory functions of the metalloregulators have made them as attractive biological parts for synthetic biology, and the exceptional sensitivity and selectivity of metalloregulators toward metal ions have been used in heavy metal biosensors to cope with prevalent heavy metal contamination. Due to their importance, substantial efforts have been made to characterize heavy metal-responsive transcriptional regulators and to develop heavy metal-sensing biosensors. In this review, we summarize the biochemical data for the two major metalloregulator families, SmtB/ArsR and MerR, to describe their metal-binding sites, specific chelating chemistry, and conformational changes. Based on our understanding of the regulatory mechanisms, previously developed metal biosensors are examined to point out their limitations, such as high background noise and a lack of well-characterized biological parts. We discuss several strategies to improve the functionality of the metal biosensors, such as reducing the background noise and amplifying the output signal. From the perspective of making heavy metal biosensors, we suggest that the characterization of novel metalloregulators and the fabrication of exquisitely designed genetic circuits will be required.

• 대한통합의학회지
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• 제8권4호
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• pp.213-221
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• 2020

Purpose : This study aimed to evaluate the changes in visual perception and daily life activities after simultaneously applying the visual perception training program and transcranial DC stimulation. Particularly, this study tried to understand what changes in abilities among daily life activities influenced cognition. Methods : This study selected 50 dementia patients to achieve the objective. This study applied transcranial DC stimulation and a visual perception training program to a treatment group (n=25) and a visual perception training program to a control group (n=25). The intervention was applied five times per week and 30 minutes per session (total of 30 intervention sessions). This study measured visual perception functions and daily life activities using MVPT and FIM before and after applying the intervention. Results : The visual perception, mobility of daily life activities, cognition, and total score of the treatment group (n=25), which received the visual perception training program and transcranial DC at the same time, were significantly (p<.05) different between before and after the intervention. Moreover, when the visual perception and daily life activities of the treatment group and those of the control group after implementing the intervention were compared, they were significantly (p<.05) different between the two groups. Conclusion : The results of this study showed that the simultaneous application of the visual perception training program and transcranial DC stimulation was an effective means to enhance the visual perception and daily life activities of dementia patients. The results implied that transcranial DC stimulation, as well as the application of visual perception training program, as well as a visual perception training program, was effective for improving the visual perception functions and daily life activities dementia patients and simultaneous application of the two interventions would increase the effect even further.