Park, Su-Jung;Kim, Ji-Hee;Ko, Han-Suk;Kim, Chong-Rak;Kim, Han-Do;Kang, Ho-Sung
Biomedical Science Letters
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v.7
no.4
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pp.167-172
/
2001
Nebulin is an approximately 700 kDa filamentous protein in vertebrate skeletal muscle. It binds to the Z line and also binds side-by-side to the entire thin actin filament in a sarcomere. The correlation of nebulin size with thin filament length have led to the suggestion that nebulin acts as a molecular ruler for the length of thin filaments. The C-terminal part of human nebulin is anchored in the sarcomeric Z-disk and contains an SH3 domain. SH3 domains have been identified in an ever-increasing number of proteins important for a wide range of cellular processes, from signal transduction to cytoskeleton assembly and membrane localization. However, the exact physiological role of SH3 domains remains, in many cases, unclear. To explore the role of nebulin SH3 in the cytoskeletal rearrangement that accompanies myoblast differentiation, we transfected sense and antisense nebulin SH3 domain fused to enhanced green fluorescent protein in myoblast. Cells expressing nebulin SH3 fragment showed decrease of cell-cell adhesion, and cells transfected with antisense nebulin SH3 gene showed a rounded cell morphology and loss of cell-matrix adhesion. No alteration in cell shape and differentiation were observed in control cells expressing enhanced green fluorescent protein. Perturbation of nebulin altered the cell shape and disrupted cell adhesion in myoblast, demonstrating that nebulin can affect cytoskeleton rearrangement.
Journal of The Korean Association of Information Education
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v.26
no.5
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pp.353-360
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2022
The purpose of this study is to verify the effect of artificial intelligence storytelling education program designed to help learning artificial intelligence based on storytelling, the most important element of human intelligence, on learning flow. To this end, a 16-hour artificial intelligence education program was designed and developed, and applied over 8 weeks to 19 gifted students in 5th and 6th grades of elementary school. Artificial intelligence storytelling education program was developed in the form of teaching and learning course plans for each class and storybooks. Artificial intelligence storytelling education program application results showed significant improvements in average scores in all 9 sub-factors of learning flow, including combination of challenges and abilities, integration of behavior and consciousness, clear goal, concrete feedback, focus on task, sense of control, loss of self-consciousness, Distortion of the sense of time, and self-purpose experience. In other words, it was confirmed that artificial intelligence storytelling education program was effective in improving learning flow.
This research is intended to study the dietary experiences by college women to promote women's health through the proper diet. The approach method was used grounded theory. The participants were selected 3 colleges in Seoul, Inchon, and Cheongju. The selected 15 women were college students who had a history of dietary experiences or who were on the way of diet at the time of the start of this research. The data were collected from August 2001 to October 2001. Data collecting method was a Focus Group Interview. The data were analysed by the Strauss and Corbin's method(1966). The results were showed that the 236 concepts in the dietary experiences were gathered into 48 sub-categories, eventually being integrated into 17 higher categories. 'Esthetic self-pursuit' is the core phenomenon of the dietary experiences. Such phenomenon is due to subjects physical problems, sense of comparison and desire of weight-loss. In the circumstantial context, the esthetic self-pursuit phenomenon is enhanced by social opinions, aesthetic senses, and the recognition of self-control. The interaction strategy of the esthetic self-pursuit can be intensified and sustained by will power, supporting systems, and accessibility. Through the dietary experiences, the body changes positive or negative figures. Following the sense of success or failure, the diet are sustained or abandoned accordingly. Therefore for the application of promoting health, an intervention strategy should be created a collect organized diet program in a social level not a private level.
The Journal of Korean Institute of Communications and Information Sciences
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v.27
no.7B
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pp.706-718
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2002
In bluetooth system, there are two kinds of interference. One is the frequency static interference, for example 802.11 direct sequence, the interferer uses fixed frequency band. Another is frequency dynamic interference, for example other piconets or 802.11 frequency hopping, the interferer uses dynamic frequency channel and cant be estimated. In this paper we introduce a novel solution of hybrid method of Listen-Before-Talk (LBT) and Adaptive Frequency Hopping (AFH) to address the coexistence of bluetooth and Direct Sequence of wireless local area network (WLAN). Before any bluetooth packet transmission, in the turn around time of the current slot, both the sender and receiver sense the channel whether there is any transmission going on or not. If the channel is busy, packet transmission is withdrawn until another chance. This is the LBT in Bluetooth. Because of asymmetry sense ability of WLAN and bluetooth, AFH is introduced to combat the left front-edge packet collisions. In monitor period of AFH, LBT is performed to label the channels with static interference. Then, all the labeled noisy channels are not used in the followed bluetooth frequency hopping. In this way, both the frequency dynamic and frequency static interference are effectively mitigated. We evaluate the solution through packet collision analysis and a detail realistic simulation with IP traffic. It turns out that the hybrid method can combat both the frequency dynamic and frequency static interference. The packet collision analysis shows it almost doubles the maximal system aggregate throughput. The realistic simulation shows it has the least packet loss.
The purpose of the study was to investigate the relationship between the degree of participation and flow for participants in ground, water, and air leisure sports-based tourism activities. A total of 437 participants' data was employed for the analyses (one-way ANOVA and multiple regression analysis) using SPSS Win 18.0 program. Main findings are as follows; First, there were differences in clear goals, transformation of time, loss of self-consciousness, challenge-skill balance, autotelic experience, unambiguous feedback, and sense of control out of flow dimensions based on types of leisure sports-based tourism activities. Second, participation period and frequence had positive effects on flow. Specifically, period had an influence on challenge-skill balance. clear goals: frequence had an effect on challenge-skill balance, transformation of time, clear goals, autotelic experience, unambiguous feedback, and sense of control: intensity had an influence on transformation of time and autotelic experience.
When various kinds of products are produced from a single energy system, the methodology which allocates the common cost to each product cost is very important because it is directly related with the profit and loss of producer and purchaser. In the cost allocation methodology of electricity and heat for CHP, there are heat method, work method, benefit distribution method, exergy method, and so on. Benefit distribution method is the most widely known worldwide, and exergy method is widely recognized among thermal engineers. As a result of review, it is judged that the rationality of benefit distribution method is low because the result deviates from common sense, and the rationality of exergy method is high because the result consistent with common sense. In accounting, it is calculated as merit methodology and the result is used for negotiations between producer and buyer, but In thermal engineering, the rationality of exergy methodology is described only as a thesis. The purpose of this study is to compare and examine the rationality of merit methodology and exergy methodology, and the aim is to describe in detail in order that producer and buyer can understand the rationality of each methodology.
Risk regarding the possibility of loss can be especially problematic. If a loss is certain to occur, it may be planned for in advance and treated as a definite, known expense. It is when there is uncertainty about the occurrence of a loss that risk becomes an important problem. The word risk is often used in connection with insurance. No one generally accepted definition of risk exists, however. Of the many definitions, two distinctive ones are commonly used. One defines risk as the variation in possible outcomes of an event based on chance. That is, the greater the number of different outcomes that may occur, the greater the risk. Another way of expressing this concept is to state: The greater the variation around an average expected loss, the greater the risk. The second definition of risk is the uncertainty concerning a possible loss. The definition of risk as a useful one because it focuses attention on the degree of risk in given situations. The degree of risk is a measure of the accuracy with which the outcome of an event based on chance can be predicted. For now, it will serve our purpose to note the more accurate the prediction of the outcome of an event based on chance, the lower the degree of risk. After sources of risks are identified and measured, a decision can be made as to how the risk should be handled. A pure risk that is not identified does not disappear, the business merely loses the opportunity to consciously decide on the best technique for dealing with that risk. The process used to systematically manage risk exposures is known as risk management. Some persons use the term risk management only in connection with businesses, and often the term refers only to the management of pure risks. In this sense, the traditional risk management goal has been to minimize the cost of pure risk to the company. But as firms broaden the ways that they view and manage many different types of risk, the need for new terminology has become apparent. The terms integrated risk management and enterprise risk management reflect the intent to manage all forms of risk, regardless of type. International trade transaction is called between countries has features of globalism, cultural gap, long distance and long terms for the transaction. It is riskier than domestic transaction has its specific risks, such as foreign exchange risk and political risk, and requires various active risk management skills. Risks in relation to the international trade transaction are the contract risk, transit risk and payment risk, etc. The risk management in relation to the international trade transaction is to identify and measure these risks. The purpose of this study is to analyse the practical problems and its solution plan by analyzing various cases related to the risk management of bill of lading in the international trade transaction.
The objective of this study was to take a closer look at the clothing benefits sought by breast cancer survivors in Korea. A qualitative descriptive study was conducted, using the focus group interview. Data was collected from members of online breast cancer forum. 18 participants were breast cancer survivors who had mastectomy or lumpectomy in their 30s~50s. The data was analyzed using content analysis in order to identify significant themes. The analysis indicated that benefits were sought after functional/comfort, health, feminity, and compensation were found. First, breast cancer survivors considered functional/comfort to be most important benefit so as to keep the body comfortable from the weather. Second, participants put the healthy body as the first priority and chose a well-being lifestyle and were likely to wear clothes made in healthy fabric, such as organic, bamboo or charcoal. Also, they preferred to look active by wearing sport brands or outdoorwear brands. Third, after the surgery, they experienced the sense of femininity loss and the sense of crisis as a woman. Single women and married women in early 30s recognized more seriously, and they tried to recover feminity by wearing clothes with feminine details. Forth, breast cancer survivor consumers tended to shop for the psychological compensation. In summary, consumers with breast cancer surgery, unlike general healthy women, did not sought to be economic, fashion, self-expression benefits, rather they sought health, femininity, and compensation benefits. Therefore, it seems necessary to develop proper products and marketing strategy to meet the said consumer's special needs.
Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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2021.05a
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pp.47-51
/
2021
In this study, we try to find out and analyze the results of reduced self-esteem and loss using text mining. Physical health is important, of course, but these days, mental health is considered more important. In order for the mind to be healthy, it is important to have self-esteem and self-confidence first. Self-esteem decreases, and if lost, it directly leads to depression. If depression is severe, the worst will lead to self-harm and suicide. However, more and more people are committing suicide these days because both ordinary people and entertainers cannot overcome depression. For this reason, the seriousness of depression and loss of self-esteem are also considered important and become an issue. Therefore, we want to collect data for a certain period of time through Naver, Instagram, and Twitter searches and extract the words of the data to anticipate and analyze the cause of loss of self-esteem, how serious the recent depression is, and what the consequences of loss of self-esteem are.
Three materials for sport underwear were manufactured by order for study, and among them, suitable material in order to perform an experiment on the effect of wearing was adopted. The results are as follows: The result of wearing an experimental clothes for sports manufactured as a foundation-type underwear for sports showed that if the same compositional materials were applied, laminating material had higher rate than that of others in the amount of sweat. Concerning relative humidity in clothes and the amount of sweat absorbed in clothes among the two kinds of materials which were produced by laminate, material 2(nylon+modal) was statistically exerts higher influence on the amount of sweat. The humidity in clothes keeps the optimal condition of 59.8%, and breast part showed the highest relative humidity. The material 2(nylon+modal) showed the highest comfortableness, the sense of warmth, humidity and voluminousness, and the sense of pressure. Follow-up survey revealed that in case of material 2, higher amount of sweat than that of the group objects in its early phase, and the amount of sweat varies from individuals. The temperature in clothes of folded parts of experimental clothes and maximum surface temperature was equivalent to that of average skin. With the lapse of time, the weight decreased of 11.03% in maximum, and 3.12% in minimum. The amount of change in the girth was greater in part of body frame than that of limbs, and especially, navel and waist part showed high decrease, and upper breast, breast and the largest part of abdomen showed relatively low decrease. The above experiment revealed that materials for suitable to the underwear for sports for loss of weight by an exercise should be made of doubled-nylon and modal, along with the laminate processing, which heightens the amount of sweat. Thus, wearing an experimental wear gave satisfaction in the view of the beauty of appearance as it did not discharge flowing secretion to the outside at the time of exercise.
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