• Title/Summary/Keyword: self-sampling device

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Comparative Assessment of a Self-sampling Device and Gynecologist Sampling for Cytology and HPV DNA Detection in a Rural and Low Resource Setting: Malaysian Experience

  • Latiff, Latiffah A;Ibrahim, Zaidah;Pei, Chong Pei;Rahman, Sabariah Abdul;Akhtari-Zavare, Mehrnoosh
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.18
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    • pp.8495-8501
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    • 2016
  • Purpose: This study was conducted to assess the agreement and differences between cervical self-sampling with a Kato device (KSSD) and gynecologist sampling for Pap cytology and human papillomavirus DNA (HPV DNA) detection. Materials and Methods: Women underwent self-sampling followed by gynecologist sampling during screening at two primary health clinics. Pap cytology of cervical specimens was evaluated for specimen adequacy, presence of endocervical cells or transformation zone cells and cytological interpretation for cells abnormalities. Cervical specimens were also extracted and tested for HPV DNA detection. Positive HPV smears underwent gene sequencing and HPV genotyping by referring to the online NCBI gene bank. Results were compared between samplings by Kappa agreement and McNemar test. Results: For Pap specimen adequacy, KSSD showed 100% agreement with gynecologist sampling but had only 32.3% agreement for presence of endocervical cells. Both sampling showed 100% agreement with only 1 case detected HSIL favouring CIN2 for cytology result. HPV DNA detection showed 86.2%agreement (K=0.64, 95% CI 0.524-0.756, p=0.001) between samplings. KSSD and gynaecologist sampling identified high risk HPV in 17.3% and 23.9% respectively (p=0.014). Conclusion: The self-sampling using Kato device can serve as a tool in Pap cytology and HPV DNA detection in low resource settings in Malaysia. Self-sampling devices such as KSSD can be used as an alternative technique to gynaecologist sampling for cervical cancer screening among rural populations in Malaysia.

Self-Collection Tools for Routine Cervical Cancer Screening: A Review

  • Othman, Nor Hayati;Zaki, Fatma Hariati Mohamad
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.8563-8569
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    • 2014
  • Sub-optimal participation is a major problem with cervical cancer screening in developing countries which have no organized national screening program. There are various notable factors such as 'embarrassment', 'discomfort' and 'no time' cited by women as they are often also the bread winners for the family. Implementation of self-sampling methods may increase their participation. The aim of this article was to provide a survey of various types of self-sampling tools which are commonly used in collection of cervical cells. We reviewed currently available self-sampling devices and collated the advantages and disadvantages of each in terms of its acceptance and its accuracy in giving desired results. In general, regardless of which device is used, self-sampling for cervical scrapings is highly acceptable to women in most of the studies cited.

First Trial of Cervical Cytology in Healthy Women of Urban Laos using by Self-sampling Instrument

  • Nabandith, Viengvansay;Pholsena, Vatsana;Mounthisone, Phouthasone;Shimoe, Kyoko;Kato, Saiko;Aoki, Kunio;Noda, Sadamu;Takamatsu, Reika;Saio, Masanao;Yoshimi, Naoki
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.9
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    • pp.4665-4667
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    • 2012
  • Cervical cancer is the most common cancer in Laos women and a screening programme, even with the PAP smear test (PAP test), has yet to be established for routine use. The Pap test is accepted as the most appropriate for cervical cancer screening in some settings but it is not commonly available in Laos hospitals, because there are few cytopathologists and gynecologists have little experience. As a pilot program, seminars for the PAP test were given in 2007 and 2008, and then PAP tests were carried out using self-sampling instrument (Kato's device) with 200 healthy volunteers in Setthathirath hospital, Laos, in 2008. The actual examination number was 196, divided into class I 104 (53.1%), class II 85 (43.3%), class IIIa 4 (2.0%), class IIIb 1 (0.5%), and class V 1 (0.5%) by modified Papanicolau classification. Four cases had menstruation. There were 6 cases with epithelial cell abnormalities including malignancy. There were 7 cases with fungus and 2 cases with trichomonas in Class II. More than 70% volunteers felt comfortable with the Kato's device and wanted to use it next time, because of the avoidance of the embarrassment and a low cost as compared with pelvic examination by gynecologists. This first trial for PAP test for healthy Laos women related to a hospital found three percent to have abnormal cervical epithelial cells. Therefore, this appraoch using a self-sampling device suggests that it should be planned for cervical cancer prevention in Laos.

Assessment of the Reliability of a Novel Self-sampling Device for Performing Cervical Sampling in Malaysia

  • Latiff, Latiffah A.;Rahman, Sabariah Abdul;Wee, Wong Yong;Dashti, Sareh;Asri, Andi Anggeriana Andi;Unit, Nor Hafeeza;Li, Shirliey Foo Siah;Esfehani, Ali Jafarzadeh;Ahmad, Salwana
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.2
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    • pp.559-564
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    • 2015
  • Background: The participation of women in cervical cancer screening in Malaysia is low. Self-sampling might be able to overcome this problem. The aim of this study was to assess the reliability of self-sampling for cervical smear in our country. Materials and Methods: This cross-sectional study was conducted on 258 community dwelling women from urban and rural settings who participated in health campaigns. In order to reduce the sampling bias, half of the study population performed the self-sampling prior to the physician sampling while the other half performed the self-sampling after the physician sampling, randomly. Acquired samples were assessed for cytological changes as well as HPV DNA detection. Results: The mean age of the subjects was $40.4{\pm}11.3years$. The prevalence of abnormal cervical changes was 2.7%. High risk and low risk HPV genotypes were found in 4.0% and 2.7% of the subjects, respectively. A substantial agreement was observed between self-sampling and the physician obtained sampling in cytological diagnosis (k=0.62, 95%CI=0.50, 0.74), micro-organism detection (k=0.77, 95%CI=0.66, 0.88) and detection of hormonal status (k=0.75, 95%CI=0.65, 0.85) as well as detection of high risk (k=0.77, 95%CI=0.4, 0.98) and low risk (K=0.77, 95%CI=0.50, 0.92) HPV. Menopausal state was found to be related with 8.39 times more adequate cell specimens for cytology but 0.13 times less adequate cell specimens for virological assessment. Conclusions: This study revealed that self-sampling has a good agreement with physician sampling in detecting HPV genotypes. Self-sampling can serve as a tool in HPV screening while it may be useful in detecting cytological abnormalities in Malaysia.

Acceptability of Self-Sampling HPV Testing Among Thai Women for Cervical Cancer Screening

  • Oranratanaphan, Shina;Termrungruanglert, Wichai;Khemapech, Nipon
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.17
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    • pp.7437-7441
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    • 2014
  • Background: Acceptability of self-sampling HPV testing is confirmed worldwide. However, some cultural differences may affect this question. Therefore, this study was conducted to evaluate the acceptability of self-sampling HPV testing in Thai women. Materials and Methods: One hundred women aged 30-65 years with an intact cervix were included in this study. The participants were asked to do the Pap test by physicians and then brush type self-sampling instruments were assigned for self-collection and finally completed a questionnaire for acceptability evaluation. The questionnaire contains 2 parts. Part one covered general information of the participants and part two is the acceptability questions. Results: Mean age was 40.6 years. The incidence of high risk HPV detection in this study was 16%. The most common reason for doing Pap smear was for annual checkup. On the topic of ease of use, 85 % of the subjects agreed. Most of the participants (82%) reported that they felt less pain. However, reliability of the result was not satisfactory because 37% of the participants hesitated to rely on the results of the test. According to the price, if the price is less than 1,000 Baht (32.59 Baht = 1USD), 82% of the subjects would use it for their next screening. Conclusions: The acceptability of self-sampling device in this study is quite good but the reliability of the test was questioned by some of the participants. Moreover, the price of the test in Thailand may also influence the acceptability of the test.

Design of a 7-bit 2GSPS Folding/Interpolation A/D Converter with a Self-Calibrated Vector Generator (자체보정 벡터 발생기를 이용한 7-bit 2GSPS A/D Converter의 설계)

  • Kim, Seung-Hun;Kim, Dae-Yun;Song, Min-Kyu
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.48 no.4
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    • pp.14-23
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    • 2011
  • In this paper, a 7-bit 2GSPS folding/interpolation A/D Converter(ADC) with a Self-Calibrated Vector Generator is proposed. The ADC structure is based on a folding/interpolation architecture whose folding/interpolation rate is 4 and 8, respectively. A cascaded preprocessing block is not only used in order to drive the high input signal frequency, but the resistive interpolation is also used to reduce the power consumption. Based on a novel self-calibrated vector generator, further, offset errors due to device mismatch, parasitic resistors. and parasitic capacitance can be reduced. The chip has been fabricated with a 1.2V 0.13um 1-poly 7-metal CMOS technology. The effective chip area including the calibration circuit is 2.5$mm^2$. SNDR is about 39.49dB when the input frequency is 9MHz at 2GHz sampling frequency. The SNDR is improved by 3dB with the calibration circuit.

Measurement of nursing students' sleep using by an automated wireless sleep tracker and subjective sleep scales (간호대학생에서 자동화 무선 수면추적기와 주관적 수면도구를 이용한 수면측정)

  • Kim, Mi Jong
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.19 no.4
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    • pp.434-443
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    • 2012
  • Purpose: This study was conducted to investigate sleep patterns in nursing students as measured by an automated wireless sleep tracker and self-reported sleep scales. Methods: Data were collected from October, 2011 to May, 2012. ZQ (a symbolic number that measures the quality and quantity of sleep) was calculated from the automated wireless sleep tracker. Pittsburgh Sleep Quality Index-Korean version, Sleep scale A, and sleep satisfaction were used as self-report sleep scales. Female nursing college students (n=37) were recruited by convenience sampling. Before going to bed, they were asked to put on a head-band type sleeping sensor and to move it the next morning. Every student slept 2~4 nights with the sleep tracker. Data were collected for 86 (91.4%) of 94 nights' sleep. The students were also requested to fill in the PSQI-K, sleep scale A, and sleep satisfaction. Results: The only statistically significant correlation was between ZQ and sleep satisfaction (r=.869, p=.026). The biggest obstacle in using this device was putting on the head-band type sensor. Conclusion: Validity of the wireless sleep tracker was verified in part. The usefulness of this device in nursing research and practice was identified. Further evaluation need to be conducted with various populations.

Comparator design using high speed Bipolar device (고속 Bipolar 소자를 이용한 comparator 설계)

  • Park Jin-Woo;Cho Jung-Ho;Gu Young Sea;An Chel
    • Proceedings of the IEEK Conference
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    • 2004.06b
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    • pp.351-354
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    • 2004
  • This thesis presents Bipolar transistor with SAVEN(Self-Aligned VErtical Nitride) structure as a high-speed device which is essential for high-speed system such as optical storage system or mobile communication system, and proposes 0.8${\mu}m$ BiCMOS Process which integrates LDD nMOS, LDD pMOS and SAVEN bipolar transistor into one-chip. The SPICE parameters of LDD nMOS, LDD pMOS and SAVEN Bipolar transistor are extracted, and comparator operating at 500MHz sampling frequency is designed with them. The small Parasitic capacitances of SAVEN bipolar transistor have a direct effect on decreasing recovery time and regeneration time, which is helpful to improve the speed of the comparator. Therefore the SAVEN bipolar transistor with high cutoff frequency is expected to be used in high-speed system.

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Factors influencing on smart health

  • Kim, Mincheol;Chen, Li;Park, Sangwon
    • The Journal of Industrial Distribution & Business
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    • v.10 no.2
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    • pp.17-23
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    • 2019
  • Purpose - This study aims to clarify the impact of smart health gadgets (specfically, smart watches/sports wristbands) on promoting healthy behavior. It also aims to understand the use and characteristics of the devices, to explore the relationship between device factors and factors that affect healthy behavior, and to discuss the development of health promotion. Research, design, data, and methodology - Smart device users were investigated through a random sampling method of 185 respondents, including all ages and all levels of occupation, education, and income. The SmartPLS 3.0 software enabled the path analysis and the descriptive statistical analysis; the theoretical model was evaluated for the parameter analysis. Results - The size and path of each factor impacting health promoting behavior were ascertained. The objective factors that attract users to the smart wristband were investigated as well as the methods by which the device and the HPM are bound to each other and the correlation factors to seek out the closest relationship. Conclusions - According to the analysis, the real-time smart watch/sports wristband exerts a positive impact on one's health promoting behavior. Health awareness is increasingly promoted in the process of using the device, and the impact of health awareness and self-efficacy effects on healthy behavior is considerable.

Energy Efficient Sequential Sensing in Multi-User Cognitive Ad Hoc Networks: A Consideration of an ADC Device

  • Gan, Xiaoying;Xu, Miao;Li, He
    • Journal of Communications and Networks
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    • v.14 no.2
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    • pp.188-194
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    • 2012
  • Cognitive networks (CNs) are capable of enabling dynamic spectrum allocation, and thus constitute a promising technology for future wireless communication. Whereas, the implementation of CN will lead to the requirement of an increased energy-arrival rate, which is a significant parameter in energy harvesting design of a cognitive user (CU) device. A well-designed spectrum-sensing scheme will lower the energy-arrival rate that is required and enable CNs to self-sustain, which will also help alleviate global warming. In this paper, spectrum sensing in a multi-user cognitive ad hoc network with a wide-band spectrum is considered. Based on the prospective spectrum sensing, we classify CN operation into two modes: Distributed and centralized. In a distributed network, each CU conducts spectrum sensing for its own data transmission, while in a centralized network, there is only one cognitive cluster header which performs spectrum sensing and broadcasts its sensing results to other CUs. Thus, a wide-band spectrum that is divided into multiple sub-channels can be sensed simultaneously in a distributed manner or sequentially in a centralized manner. We consider the energy consumption for spectrum sensing only of an analog-to-digital convertor (ADC). By formulating energy consumption for spectrum sensing in terms of the sub-channel sampling rate and whole-band sensing time, the sampling rate and whole-band sensing time that are optimal for minimizing the total energy consumption within sensing reliability constraints are obtained. A power dissipation model of an ADC, which plays an important role in formulating the energy efficiency problem, is presented. Using AD9051 as an ADC example, our numerical results show that the optimal sensing parameters will achieve a reduction in the energy-arrival rate of up to 97.7% and 50% in a distributed and a centralized network, respectively, when comparing the optimal and worst-case energy consumption for given system settings.