• Human Ecology Research
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• v.57 no.3
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• pp.445-457
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• 2019

This study investigated the impact of parentification on ambivalence over the emotional expression of early adults who had a sibling with disabilities and examined if rejection sensitivity moderated the relationship of parentification and ambivalence over emotional expression. Participants consisted of 116 siblings in early adulthood who had a sibling with disabilities (45 male; 71 female). The data were collected from 13 centers for family disability, four community rehabilitation centers, three parent societies for people with disabilities, and three self-help groups in Seoul, Busan, and Gyeonggi province. The levels of ambivalence over emotional expression, parentification, and rejecton sensitivity were measured by the Ambivalence over Emotional Expression Questionnaire (King & Emmons, 1990), the Filial Responsibility Scale-Adult (Jurkovic, Thirkield, & Morrell, 2001), and the Rejection Sensitivity Questionnaire (Downey & Feldman, 1996), respectively. The PROCESS Macro program examined the moderating model. The Results indicated that both levels of parentification and rejection sensitivity increased the level of ambivalence over emotional expression of non-disabled siblings. In addition, rejection sensitivity moderated the effect of parentification on ambivalence over emotional expression. The influence of parentification on ambivalence over emotional expression was greater when the level of rejection sensitivity was high, compared to when it was low.

• Journal of East-West Nursing Research
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• v.14 no.2
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• pp.54-59
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• 2008

Purpose: To investigate self-esteem according to differences between real and ideal Body Mass Index (BMI) in female college students. Methods: Subjects were 587 female students in Korea. Data was collected by using a developed questionnaire through pretesting. Results: Actual number (46.7%) and actual number (5.1%) of participants were defined as being underweight and overweight, respectively. Nearly all participants expression high dissatisfaction with their body shape. Averages of 1.02, 2.97, 7.81 were revealed for underweight, normal weight and overweight group differences between real and ideal BMI. Those who were defined as overweight exhibited significantly self-esteem than those who were defined as underweight. Conclusions: The belief that body shape is heavier than actually the case may be prevalent among female college students in Korea. This difference between the real and ideal BMI negatively influences self-esteem. Programs aimed at improving body image awareness an self-esteem among female college students are needed.

• Journal of Ginseng Research
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• v.43 no.3
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• pp.421-430
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• 2019

Background: The ginsenoside Rg3, one of active components of red ginseng, has chemopreventive and anticancer potential. Cancer stem cells retain self-renewal properties which account for cancer recurrence and resistance to anticancer therapy. In our present study, we investigated whether the standardized Korean Red Ginseng extract (RGE) and Rg3 could modulate the manifestation of breast cancer stem cell-like features through regulation of self-renewal activity. Methods: The effects of RGE and Rg3 on the proportion of $CD44^{high}/CD24^{low}$ cells, as representative characteristics of stem-like breast cancer cells, were determined by flow cytometry. The mammosphere formation assay was performed to assess self-renewal capacities of breast cancer cells. Aldehyde dehydrogenase activity of MCF-7 mammospheres was measured by the ALDEFLUOR assay. The expression levels of Sox-2, Bmi-1, and P-Akt and the nuclear localization of hypoxia inducible $factor-1{\alpha}$ in MCF-7 mammospheres were verified by immunoblot analysis. Results: Both RGE and Rg3 decreased the viability of breast cancer cells and significantly reduced the populations of $CD44^{high}/CD24^{low}$ in MDA-MB-231 cells. RGE and Rg3 treatment attenuated the expression of Sox-2 and Bmi-1 by inhibiting the nuclear localization of hypoxia inducible $factor-1{\alpha}$ in MCF-7 mammospheres. Suppression of the manifestation of breast cancer stem cell-like properties by Rg3 was mediated through the blockade of Akt-mediated self-renewal signaling. Conclusion: This study suggests that Rg3 has a therapeutic potential targeting breast cancer stem cells.

• BMB Reports
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• v.51 no.2
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• pp.92-97
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• 2018

B cell leukemia/lymphoma 3 (Bcl3) plays a pivotal role in immune homeostasis, cellular proliferation, and cell survival, as a co-activator or co-repressor of transcription of the $NF-{\kappa}B$ family. Recently, it was reported that Bcl3 positively regulates pluripotency genes, including Oct4, in mouse embryonic stem cells (mESCs). However, the role of Bcl3 in the maintenance of pluripotency and self-renewal activity is not fully established. Here, we report the dynamic regulation of the proliferation, pluripotency, and self-renewal of mESCs by Bcl3 via an influence on Nanog transcriptional activity. Bcl3 expression is predominantly observed in immature mESCs, but significantly decreased during cell differentiation by LIF depletion and in mESC-derived EBs. Importantly, the knockdown of Bcl3 resulted in the loss of self-renewal ability and decreased cell proliferation. Similarly, the ectopic expression of Bcl3 also resulted in a significant reduction of proliferation, and the self-renewal of mESCs was demonstrated by alkaline phosphatase staining and clonogenic single cell-derived colony assay. We further examined that Bcl3-mediated regulation of Nanog transcriptional activity in mESCs, which indicated that Bcl3 acts as a transcriptional repressor of Nanog expression in mESCs. In conclusion, we demonstrated that a sufficient concentration of Bcl3 in mESCs plays a critical role in the maintenance of pluripotency and the self-renewal of mESCs via the regulation of Nanog transcriptional activity.

• Journal of Korean Clinical Health Science
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• v.8 no.2
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• pp.1436-1443
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• 2020

Purpose: The purpose of this study was to differences in the expression rate of Porphyromonas gingivalis according to smoking status, smoking amount and period of smoking. Methods: At the time of investigation, 30 smokers and non-smokers were recruited among patients with periodontitis with a probing pocket depth(PPD) of 4 mm or more. General information was collected using a self-questionnaire, and the average value was used by a dentist to measure the probing pocket depth of three times each for the first or second molar. Plaque collection and analysis were performed by collecting only subgingival plaque using a conventional method, and the expression rate of P. gingivalis was confirmed using polymerase chain reaction (PCR). For statistical analysis, the SPSS Ver 25.0 program was used. Results: Smoking did not have a significant effect on the expression of P. gingivalis, but it did affect the expression of more type II genotypes (p<0.05). In addition, smokers had more slight periodontal pocket, and the amount and duration of smoking did not affect the expression of P. gingivalis. Conclusions: In the future, it is necessary to reinforce the group of smokers and non-smokers with healthy oral conditions, and to investigate the quantitative difference in the expression rate and genotype of P. gingivalis over time of harmful substances in smoking.

• Journal of Families and Better Life
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• v.20 no.2
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• pp.203-214
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• 2002

This study of the relationships between children's depression and anxiety and their children's self-esteem and emotional intelligence had a sample of 984 5th grade children The higher the levels of children's depression and anxiety were, the lower their self-esteem consisting of scholastic competence, social acceptance, atheletic competence, physical appearance, behavioral conduct, and global self-worth were. The higher the levels of children's depression and anxiety were, the lower their emotional intelligence(EI) consisting of self-regulation and emotion utilization, perception of emotion, other-regulation and self-expression were. For boys, scholastic competence and social competence among children's self-esteem factors were the factors best explained by children's depression and anxiety. In addition, boy's perception of emotion was explained by their depression and anxiety. For girls, on the other hand global self-worth and social competence among self-esteem factors were the two factors best explained by their depression and anxiety. Self-regulation and emotion utilization was the El factor best explained by depression and anxiety among girls.

• Journal of Fashion Business
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• v.2 no.2
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• pp.66-76
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• 1998

The purpose of this study was to examine the proximity of clothing to self and proximity of cosmetic to self by Degree of Cosmetics. The scales used in this study include the arranged on the basis of Sontag (1978) 's study for proximity of clothing to self, and the scale developed by the researcher for proximity of cosmetic to self. The subjects of this study were 885 adult women in Taegu. The data collected were analyzed by using MANOVA, ANOVA, and the Cronbach a was also applied. The results of this study were summarized as follows: 1. The persons with high degree of cosmetics showed high degrees of joy of change, self-value expression, novelty, self-consciousness and consciousness to others in the sub-factors of proximity of clothing to self, while there was not significant difference in physical satisfaction. 2. The persons with high degree of cosmetics showed high degrees of social confidence, skin care, joy of change, self-satisfaction, instrument of disguise in the sub-factors of proximity of cosmetic to self.

• International Journal of Advanced Culture Technology
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• v.11 no.4
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• pp.429-434
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• 2023

This is a single-group pre-post study conducted to determine the effect of a calligraphy program on nursing students' career decision-making self-efficacy and self- leadership. The data collected from 231 second-year nursing students were analyzed using SPSS WIN 25.0 to determine descriptive statistics, paired t-test to analyze the effect of calligraphy, and Pearson correlation coefficient to determine the relationship between career decision self-efficacy and self-leadership. After the program, both career decision self-efficacy (t=7.23, p<.001) and self-leadership (t=6.81, p<.001) improved. The analysis of career decision self-efficacy and self-leadership after the program showed a strong correlation (r=.849, p<.001). The results of this study are significant in that they validate the effectiveness of a calligraphy program in promoting self-leadership and career decision-making self-efficacy among nursing students who do not have clear career goals. Students' overall satisfaction with the calligraphy program was 4/5 points, and they most highly evaluated the smooth interaction between fellow students through the program. At a time when the importance of cultural arts education is gradually increasing in social and educational fields around the world, calligraphy has the advantage of laying the foundation for the promotion of basic arts for the revitalization of cultural arts, so educational support is needed not only in terms of improving the quality of life and pursuing self-actualization of individuals with emotional expression and creative problem-solving skills, but also at the social level.

• Journal of The Korea Institute of Healthcare Architecture
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• v.11 no.2
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• pp.63-71
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• 2005

The purpose of this study is to find the complementary idea of the psychological elements in aesthetic expression of architectural space in the sense of healing. Marks $L\ddot{u}scher$, the swiss psychologist suggested reasonable categories of emotional character according to the couple combinations among Content, Self-Esteem, Confidence, and Liberty. His theory on healing is not only the concept but the practical method to understand and control the conflict between contrary elements of emotion. Compared to the Freud's objective theory of cause and consequence, his idea is focused on the subjective and autonomous harmony. This theory based on complementary idea is applied to psychological attitude of architects on Spatial Expression in this study. Refuge, Prospect, Flow and Void are assumed as equivalent spatial elements to the four major emotional conditions suggested by $M.L\ddot{u}scher$. The couple combinations among them also characterize the architectural characters definitely and it is expected to be the reasonable criteria in analysing aesthetic value and motive of creating human space.

• Journal of Korean Academy of Nursing Administration
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• v.16 no.4
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• pp.428-436
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• 2010

Purpose: The purposes of this study were to describe events resulting in perceived hurts in nursing, and to identify factors influencing forgiveness in clinical nurses. Methods: The study was a descriptive correlation design. From May to July, 2009, the researcher used interviews to collect data from 148 clinical nurses from five hospitals in D city. Results: Clinical nurses received perceived hurt from peer-nurses, care-givers, and doctors, and the reasons for the perceived hurts were blame, neglect, and valuation. Levels of forgiveness in clinical nurses were different according to who caused the perceived hurt, the degree of the perceived hurt, and endeavors to resolve the perceived hurts. Levels of forgiveness in clinical nurses were negatively correlated with age, degree of perceived hurt, and degree of anger expression, and positively correlated with degree of self-esteem. The strongest predictors of forgiveness in clinical nurses were degree of anger expression, age, and degree of hurt. Conclusion: The findings of the study suggest that nursing staff should be able to identify reasons for perceived hurt in clinical nurses and provide a forgiveness program for each nursing situation.