• Journal of the Korean Applied Science and Technology
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• v.36 no.3
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• pp.804-812
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• 2019

The purpose of this study was to investigate the effects of different types of exercise training on neurodegeneration and cognitive function in mice with impaired glucose tolerance (IGT). Thirty-six male C57BL/6 mice were randomly assigned to the control (CO, n = 9) and impaired glucose tolerance (IGT, n = 27) groups. The IGT group consumed 45% high fat diet for 4 weeks and received 40 mg/kg of streptozotocin twice in the lower abdomen to induce IGT. After the IGT induction period, the IGT group was subdivided into IGT + sedentary (IGT, n = 9), IGT + endurance exercise (IGTE, n = 9), and IGT + resistance exercise (IGTR, n = 9). The IGTE and IGTR groups performed treadmill and ladder climbing exercises 5 times per week for 8 weeks, respectively. Fasting glucose and glycated hemoglobin (HbA1c) levels were significantly higher in IGT group than in CO, IGTE, and IGTR groups (p < 0.05). HOMA-IR was significantly higher in IGT group than CO group (p < 0.05). Hippocampal catalase (CAT) was significantly lower in IGT group than in CO group (p < 0.05), while beta-amyloid ($A{\beta}$) was significantly higher in IGT group than in CO group (p < 0.05). Hippocampal tau was significantly higher in IGT group than in CO, IGTE, and IGTR groups (p < 0.05). The Y-maze test performance for cognitive function was significantly lower in IGT group than in CO, IGTE, and IGTR groups (p <0.05). These results suggest that IGT induces neurodegeneration and negatively affects cognitive function, while regular exercise may be effective in alleviating neurodegeneration and cognitive decline regardless of exercise type.

• Journal of Environmental Health Sciences
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• v.45 no.1
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• pp.1-8
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• 2019

Objectives: The purpose of this study was to estimate the ventilation rate of residential homes in Korea through tracer gas methods using indoor and outdoor concentrations of carbon dioxide ($CO_2$) and $CO_2$ generation rates from breathing. Methods: In this study, we calculated the number of occupants in a home by time through data on the average number of people per household from the Korean National Statistical Office and also measured the amount of $CO_2$ generation by breathing to estimate the indoor $CO_2$ generation rate. To estimate the ventilation rate, several factors such as the $CO_2$ generation rate and average volume of residential house provided by the Korean National Statistical Office, indoor $CO_2$ concentrations measured by sensors, and outdoor $CO_2$ concentrations provided by the Korea Meteorological Administration, were applied to a mass balance model for residential indoor environments. Results: The average number of people were 2.53 per household and Koreans spend 61.0% of their day at home. The $CO_2$ generation rate from breathing was $13.9{\pm}5.3L/h$ during sleep and $15.1{\pm}5.7L/h$ in a sedentary state. Indoor and outdoor $CO_2$ concentrations were 849 ppm and 407 ppm, respectively. The ventilation rate in Korean residential houses calculated by the mass balance model were $42.1m^3/h$ and 0.71 air change per hour. Conclusions: The estimated ventilation rate tended to increase with an increase in the number of occupants. Since sensor devices were used to collect data, sustainable data could be collected to estimate the ventilation rate of Korean residential homes, which enables further studies such as on changes in the ventilation rate by season resulting from the activities of occupants. The results of this study could be used as a basis for exposure and risk assessment modeling.

• Journal of Life Science
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• v.31 no.11
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• pp.1037-1045
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• 2021

The prevalence of obesity is increasing worldwide, and since obesity is associated with dietary factors and sedentary lifestyles, it is a disease that is readily developing in the modern population. Because obesity is accompanied by serious complications such as diabetes and cardiovascular disease, prevention and treatment are important. Currently, drugs such as liraglutide and phentermine are used to treat obesity by suppressing appetite and inducing gastrointestinal motility delay. However, various side effects may occur, including thyroid cancer, cardiovascular problems, and central nervous system disorders. Therefore, to explore an obesity treatment method with relatively few side effects, a method known as "fat browning" was introduced to change white adipose tissue into brown adipose tissue to increase energy consumption. Ongoing studies are attempting to find effective natural substances to safely induce browning. Many natural substances have been identified. The induction of browning by treatment with natural substances generally involves three mechanisms: positive control of browning-inducing factors, inhibition of differentiation into white adipose tissue, and the activation of mechanisms related to browning. In this study, we describe plant extracts with known browning-inducing effects, such as strawberry, black raspberry, cinnamomum cassia, and Ecklonia stolonifera extracts. We also summarize the underlying mechanisms of action identified thus far, including the signaling pathway mediated by these extracts to induce browning. Furthermore, the effects of brown adipose tissue generated through browning on heart disease as an endocrine organ disruptor are discussed.

• Journal of the Korea Society of Computer and Information
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• v.27 no.2
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• pp.153-161
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• 2022

Physical activities are decreasing and sitting time is increasing due to the automation, smartization, and intelligence of necessary household items throughout daily life. Recent healthcare studies have reported that the likelihood of obesity, diabetes, cardiovascular disease, and early death increases in proportion to sitting time. In this paper, we develop a sitting posture correction cushion in real time using capacitive pressure sensor based on conductive textile. It develops a pressure sensor using conductive textile, a key component of the posture correction cushion, and develops a low power-based pressure measurement circuit. It provides a function to transmit sensor values measured in real time to smartphones using BLE short-range wireless communication on the posture correction cushion, and develops a mobile application to check the condition of the sitting posture through these sensor values. In the mobile app, you can visualize your sitting posture and check it in real time, and if you keep it in the wrong posture for a certain period of time, you can notify it through an alarm. In addition, it is possible to visualize the sitting time and posture accuracy in a graph. Through the correction cushion in this paper, we experiment with how effective it is to correct the user's posture by recognizing the user's sitting posture, and present differentiation and excellence compared to other product.

• 한국체육학회지인문사회과학편
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• v.55 no.4
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• pp.507-516
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• 2016

The purpose of this study is to identify the effects of PPARβ/δ over-expression on PGC-1α mRNA and protein stability after single bout of swimming exercise in mice skeletal muscle. Empty vector (EV) or PPARβ/δ was over-expressed in tibialis anterior(TA) using electroporation(EPO) technique to compare with non-treatment muscle(control; Con). TA muscles were dissected at 0h, 24h or 54h after termination of exercise. PGC-1α mRNA in Con, EV and PPARβ/δ over-expressed muscles were increased 6.8 fold (p<.001), 6.2 fold(p<.001) and 7.1 fold(p<.001), respectively, than sedentary(Sed) group at 0h after exercise and then reverted to Sed group levels at 24h and 54h after termination of exercise. PGC-1α and PGC-1α ubiquitination in EV treated muscles were increased 2.2 fold and 1.74 fold, respectively, than Sed group at 24h after termination of exercise, and then reverted to Sed group levels at 54h after termination of exercise. PGC-1α in PPARβ/δ over-expressed muscles at 24h and 54h after termination of exercise were increased 2.5 fold and 2.2 fold, respectively, than Sed group, but PGC-1α ubiquitination was not increased at 24h and 54h after termination of exercise. Our results indicate that PPARβ/δ over-expression does not increase PGC-1α mRNA stability, but increase PGC-1α protein stability through post-translation mechanism after termination of exercise.

• 한국체육학회지인문사회과학편
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• v.55 no.3
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• pp.465-472
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• 2016

The purpose of this study was to analyze the amount of physical activity and body composition and to investigate physical activity according to cancer type, sex, and age among colorectal and gastric cancer survivors. A total of 354 participants who were colorectal (n=185) and gastric (n=169) cancer survivors had completed all treatment less than 4 years ago at Y university hospital between June 2014 and April 2015. The Global Physical Activity Questionnaire (GPAQ) was used to measure time and intensity of physical activity according to the different types of activity. The colorectal cancer survivors were significantly higher in body mass index, waist circumference, percent body fat, blood pressure, and the prevalence of diabetes compared to gastric cancer survivors. In addition, the results showed that only 26.5% of colorectal cancer survivors met American College of Sports Medicine (ACSM) guidelines (at least of 150 min of moderate intensity of higher physical activity per week) for physical activity, compared with 41.4% of gastric cancer survivors. Additionally, only 13.6% of colorectal and gastric cancer survivors met strength exercise guidelines. The male cancer survivors were significantly higher in moderate physical activity, participation in resistance exercise, and sedentary behaviors compared to female cancer survivors. In additions, less than 65 years cancer survivors were higher in strenuous intensity exercise and moderate physical activity compared to more than 65 years cancer survivors. The alternative for promoting physical activity participation rates of colorectal and gastric cancer survivors should be presented.

• The Journal of Korean Philosophical History
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• no.29
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• pp.179-202
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• 2010

In addition to the emphasis on filial piety ethics in everyday life, filial piety obtained a further significance in Confucianism which had the strong sense of ancestor worship. This paper focuses on filial piety as a mechanism of continuity within Confucianism and points out that it owed its development to its connection to agricultural culture. The sedentary life with less mobility forged a relative intimacy among people and filial piety was the actual expression of that kind of intimate affection. Yet, filial piety in Confucianism created a unique culture in terms that it not only stipulated material and emotional support for parents but also expected one's piety to the further ancestors through a memorial service and made its connection to the infinite posterity through sons. From the perspective of Confucianism that established filial piety at the turning point from life to death, the self existing in present was not an isolated self anymore. Yet, one can see another characteristic of Confucianism from that filial piety, based on blood bonds, could move beyond paternalism to broaden itself. It could be expanded to the care for strangers. The aged experience and wisdom through agricultural life begot the insight that the nature made its infinite connections with everything through circulation. As a stone thrown in a pond would enlarge its boundary by drawing larger and larger concentric circles, this thought enabled people to enlarge their affection to their parents to universal humanity. In this enlarged network, though it was natural to make distinctions between the closer and the farther, Confucianism sought to overcome it by establishing oneself upright. Confucianism emphasized the moral cultivation with its filial piety concept that contained the diachronic thought penetrating life and death and the broadened perspective relating everything around. In Confucianism, filial piety provided an important medium in forming a moral subject that penetrated life and death and related self and others. Inherent in it is the Confucius thought of continuity that searched for a paragon of a moral human being regardless of time and space.

• 한국노년학
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• v.31 no.2
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• pp.303-315
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• 2011

The purpose of this study was to investigate effect of resistance training on BMD and bone metabolism related markers in aging rats. Thirty male Spraugue-Daweley rats were divided into sedentary (CON; n=10 ) non-load resistance trained(NLRTG; n=10), and load resistance trained(LRTG; n=10) groups at the age of 64 weeks. The rats in the resistance training groups((NLRTG and LRTG) performed the tower climbing exercise 4 times a week. The LRTG groups were conditioned to climb a vertical ladder with weights appended to their tail 4 days/wk for 12 wks. After 12 weeks of exercise, serum osteocalcin, bone mineral density (BMD), breaking force, ash, Ca, and P in the femur were measured. After training, serum osteocalcin (OC) was significantly (p < 0.05) higher in both LRTG and NLRTG when compared to Control. Right femur BMD was significantly (p < 0.05) greater for LRTG when compared to both NLRTG and Control with no significant difference between NLRTG and Conrtol. The breaking force of femur was significantly (p < 0.05) greater for LRTG and NLRTG when compared to Control. The Ash, Ca, content of femur were significantly increased in resistance training groups than control group. These results suggest that the increase in bone mineral density induced by resistance training is mediated by changes in bone microarchitecture as well as training intensity and osteocalcin.

• Journal of Industrial Convergence
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• v.22 no.6
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• pp.107-120
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• 2024

This study aimed to identify factors associated with metabolic abnormalities in non-obese and obese postmenopausal women based on biopsychosocial model. Secondary data analysis was conducted using data from 5,335 postmenopausal women who participated in the Korean National Health and Nutrition Examination Survey (2015-2021). According to logistic analysis with applying a complex simple analysis in SPSS 26.0, biomedical (increased age; a family history of hypertension, type 2 diabetes, dyslipidemia, and cardiovascular diseases) and biosocial factors (low educational level) were associated with 1-2 metabolic abnormalities and metabolic syndrome, regardless of adiposity. Additionally, low familial socioeconomic status and prolonged sedentary behaviors were the biosocial and psychosocial factors associated with metabolic syndrome regardless of adiposity. Finally, insufficient physical activity was associated with metabolic syndrome in obese postmenopausal women. Based on these results, tailored strategies should be developed considering the significant factors associated with metabolic abnormalities and adiposity in postmenopausal women.

• Journal of the Korean association of regional geographers
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• v.3 no.2
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• pp.37-87
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• 1997

As a results of researches on the cultivation processes and settlement developments on the Mangyoung river valley as a whole could be have four 'Space-Time Continuity' through a [Origin-Destination] theory model. On a initial phases of cultivation, the cultivation process has been begun at mountain slopes and tributory plains in upper part of river-basin from Koryo Dynasty to early Chosun Dynasty. At first, indigenous peasants burned forests on the mountain slopes for making 'dryfield' for a cereal crops. Following population increase more stable food supply is necessary facets of life inducing a change production method into a 'wetfield' in tributory plains matching the population increase. First sedentary agriculture maybe initiated at this mountain slopes and tributory plains on upper part of river basin through a burning cultivation methods. Mountain slopes and tributory plains are become a Origin area in cultivation processes. It expanded from up to down through the valleys with 'a bits of land' fashion in a steady pace like a terraced fields expanded with bit by bit of land to downward. They expanded their land to the middle part of river basin in mid period of Chosun Dynasty with dike construction techniques on the river bank. Lower part of river cultivated with embankment building techniques in 1920s and then naturally expanded to the tidal marshes on the estuaries and river inlets of coastal areas. 'Pioneer fringes' are consolidated at there in modern times. Changes in landscapes are appeared it's own characters with each periods of time. Followings are results of study through the Mangyoung river valley as a whole. (1) Mountain slopes and tributory plains on the upper part of river are cultivated 'dryfields' by indigenous peasants with Burning cultivation methods at first and developed sedentary settlements at the edges of mountain slopes and on the river terrace near the fields. They formed a kind of 'periphery-located cluster type' of settlement. This type of settlement are become a prominant type in upper part of river basin. 'Dryfields' has been changed into a 'wetfields' at the narrow tributory plains by increasing population pressure in later time. These wetfields are supplied water by Weir and Ponds Irrigation System(제언수리방법). Streams on the tributory plains has been attracted wetfields besides of it and formed a [water+land] complex on it. 'Wetfields' are expanded from up to downward with a terraced land pattern(adder like pattern, 붕전) according to the gradient of valley. These periphery located settlements are formed a intimate ecological linkage with several sets of surroundings. Inner villages are expanded to Outer villages according to the expansion of arable lands into downward. (2) Mountain slopes and tributory plains expanded its territory to the alluvial deposited plains on the middle part of river valley with a urgent need of new land by population increase. This part of alluvial plains are cultivated mainly in mid period of Chosun Dynasty. Irrigation methods are changed into a Dike Construction Irrigation method(천방수리방법) for the control of floods. It has a trend to change the subjectives of cultivation from community-oriented one who constructed Bochang along tributories making rice paddies to local government authorities who could be gather large sums of capitals, techniques and labours for the big dike construction affairs. Settlements are advanced in the midst of plains avoiding friction of distances and formed a 'Centrallocated cluster type' of settlements. There occured a hierarchical structures of settlements in ranks and sizes according merits of water supply and transportation convenience at the broad plains. Big towns are developed at there. It strengthened a more prominant [water+land] complex along the canals. Ecological linkages between settlements and surroundings are shaded out into a tiny one in this area. (3) It is very necessary to get a modern technology of flood control at the rivers that have a large volume of water and broad width. The alluvial plains are remained in a wilderness phase until a technical level reached a large artificial levee construction ability that could protect the arable land from flood. Until that time on most of alluvial land at the lower part of river are remained a wilderness of overgrown with reeds in lacks of techniques to build a large-scale artificial levee along the riverbank. Cultivation processes are progressed in a large scale one by Japanese agricultural companies with [River Rennovation Project] of central government in 1920s. Large scale artificial levees are constructed along the riverbank. Subjectives of cultivation are changed from Korean peasants to Japanese agricultural companies and Korean peasants fell down as a tenant in a colonial situation of that time in Korea. They could not have any voices in planning of spatial structure and decreased their role in planning. Newly cultivated lands are reflected company's intensions, objectives and perspectives for achieving their goals for the sake of colonial power. Newly cultivated lands are planned into a regular Rectangular Block settings of rice paddies and implanted a large scale Bureaucratic-oriented Irrigation System on the cultivated plains. Every settlements are located in the midst of rice paddies with a Central located Cluster type of settlements. [water+land] complex along the canal system are more strengthened. Cultivated space has a characters of [I-IT] landscapes. (4) Artificial levees are connected into a coastal emnankment for a reclamation of broad tidal marshes on the estuaries and inlets of rivers in the colonial times. Subjectives of reclamation are enlarged into a big agricultural companies that could be acted a role as a big cultivator. After that time on most of reclamation project of tidal marshes are controlled by these agricultural companies formed by mostly Japanese capitalists. Reclaimed lands on the estuaries and river inlets are under hands of agricultural companies and all the spatial structures are formed by their intensions, objectives and perspectives. They constructed a Unit Farming Area for the sake of companies. Spatial structures are planned in a regular one with broad arable land for the rice production of rectangular blocks, regular canal systems and tank reservoir for the irrigation water supply into reclaimed lands. There developed a 'Central-located linear type' of settlements in midst of reclaimed land. These settlements are settled in a detail program upon this newly reclaimed land at once with a master plan and they have planned patterns in their distribution, building materials, location, and form. Ecological linkage between Newly settled settlemrnts and its surroundings are lost its colours and became a more artificial one by human-centred environment. [I-IT] landscapes are become more prominant. This region is a destination area of [Origin-Destination] theory model and formed a 'Pioneer Fringe'. It is a kind of pioneer front that could advance or retreat discontinously by physical conditions and socio-cultural conditions of that region.