• 한국산학기술학회논문지
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• 제20권4호
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• pp.264-274
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• 2019

본 연구는 선호하는 식물성 Base oil에 따른 클렌징 오일이 피부에 미치는 영향에 대해 알아보고자 하였다. 먼저 설문조사(100명)를 통해 세안 습관 실태 및 선호하는 식물성 Base oil를 파악하고, 이를 바탕으로 4종의 클렌징 오일을 제조하여 실험을 진행하였다. 실험은 20~30대 성인여성 10명을 대상으로 선정하여 실험 전 후 수분보유량, 유분보유량, 경피수분손실량(TEWL)을 측정하였고, 실험 후 만족도 설문조사를 실시하여 분석하였다. 그 결과, 클렌징 오일의 식물성 Base oil 종류에 따른 선호도 설문조사에서는 로즈힙 오일, 올리브 오일, 살구씨 오일, 동백 오일 순으로 나타났다. 임상 실험결과, 선호하는 식물성 Base oil에 따른 클렌징 오일(4종)의 클렌징 전 후 수분보유량과 유분보유량의 변화폭은 Base oil에 따라 차이는 있었으나 모두 증가하는 것으로 나타났다(p<0.001, p<0.001). 또한 TEWL의 변화량도 Base oil에 따라 차이는 있었으나 모두 감소하였다(p<0.01). 실험 후 주관적 만족도 설문조사 결과에서는 로즈힙 오일이 함유된 클렌징 오일(RHC)이 세정력 및 주관적인 만족도면에서 가장 높게 나타났다. 결론적으로 선호하는 식물성 Base oil에 따른 클렌징 오일이 피부의 유 수분보유량과 TEWL의 개선에 긍정적인 영향을 미쳐 피부장벽을 보호함으로서 피부개선 효과가 있음을 알 수 있었다. 따라서 개개인마다 피부타입과 선호하는 오일 및 사용감에 따른 만족도는 다르지만 본 연구의 식물성 Base oil에 따른 클렌징 오일은 단순히 세정의 차원을 넘어 피부건조와 피부장벽을 보호하는 피부보호 제품으로서 도움이 될 수 있을 것이다.

• 한방안이비인후피부과학회지
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• 제26권3호
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• pp.1-19
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• 2013

Objective : The primary purpose of present study is to evaluate the effect of herbal cosmetics containing Cortex Betulae Platyphyllae extract complex on acne. The second is to comparatively evaluate safety of this cosmetics. Methods : We opened collecting of applicant that men and women(the 18~35-year-old) with acne on face. We selected subjects who came up to entire inclusion criteria and were not included in the exclusion criteria. We checked changes of Acne Global score, skin sebum, moisture, pores counts, Skindex-29 for 8 weeks. Results : 1. Comparison of changes in Global score, it declined in both experimental group and control group. But Experimental group showed a statistically significant decline than control group. 2. Comparison of changes in sebum and moisture, it declined in both experimental group and control group. But there was no statistically significant difference between those two groups. 3. Comparison of changes in erythema normal area, it declined in both experimental group and control group. But there was no statistically significant difference between those two groups. 4. Comparison of changes in pore counts, it increased statistically significantly in both experimental group and control group. 5. Comparison of changes in Skindex-29, it declined in both experimental group and control group. But there was no statistically significant difference between those two groups. Conclusion : Considering the above experiments, it is suggested that herbal cosmetics containing Cortex Betulae Platyphyllae extract complex have a positive effect on acne.

• 한국응용과학기술학회지
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• 제32권3호
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• pp.439-450
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• 2015

으름열매는 폴리페놀과 사포닌과 같은 페놀성 물질을 많이 함유하고 있다. 본 연구는 세포실험을 통해 으름열매 추출물의 항산화활성을 확인하고, 피부에 적용하였을 때 수분과 유분, 멜라닌과 홍반변화의 효과를 측정하였다. 항산화 효과 측정결과, 농도 의존적으로 폴리페놀, 플라보노이드, DPPH소거능이 상승한 것으로 확인되었고, 으름열매 추출물 크림을 사용하였을 때 수분함량 변화, 유분함량 변화, 멜라닌지수, 홍반지수의 감소가 통계적으로 유의미한 변화를 보여 으름열매 추출물 함유 화장품이 피부개선을 위한 기능성화장품으로서 활용 가능성을 확인할 수 있었다. 따라서 본 연구에서는 으름열매 추출물은 독성을 나타내지 않으면서도 피부보습, 피부개선효과를 가진 천연 및 기능성화장품 소재로서 활용 가능성이 있다고 사료된다.

• 대한한의학회지
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• 제25권1호
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• pp.161-171
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• 2004

Objectives: Sasang Constitutional Medicine is popularly appliedto treatment in Korea. Constitution is a holistic concept contained internal and external characteristics, and physical traits including ordinary symptoms. Skin is one of constitutional property elements. So we researched a correlation female facial skin and sasang constitution. This is a basic study to find constitution can be a major factor to care and manage skin. Methods: We examined sasang constitution and facial skin condition of 100 healthy women who aged from 30 to 59. Hydration and sebum of facial skin was measured by skin diagnostic instrument and skin type was calculated from the data. Keratin, pore size, acne, and brightness of face was measured by skin magnifying lens and subjective skin troubles in ordinary times was also investigated. Constitution diagnosis and Skin diagnosis was investigated separately as a blind test andthe data was statistically analyzed with chi-square test, Correlation analysis, One-way analysis of variance. Results: 1. In sasang constitution, Taeeumingroup bad significant tendencies of larger hydration and sebum amount, combination degree of forehead and cheek was also higher than other constitutions(p<0.05). 2. Facial skin type was significantly different according to Sasang Constitution, Soeumin and Soyangin had a tendency of dry skin comparatively, but Taeeumin had mainly a tendency of combination skin and secondly dry skin(p<0.05). On the other hand, there was no correlation between age and skin type. 3. In subjective skin trouble, Soeumin group had less acne trouble than Soyangin and Taeeumin group(p<0.1). Pore size trouble was more frequent in Soyangin group than Soeumin group(p<0.05). Keratin trouble was more frequent in Soeumin group than Soyangin and Taeumin group(p<0.1). Conclusions: Korean healthy women's skin condition was different according to sasang constitution.

• 대한화장품학회:학술대회논문집
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• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book II
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• pp.253-267
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• 2003

Inositol and phytic acic extracted from rice bran were investigated for applying cosmetics. Skin lotions containing 0∼3.0wt% inositol and 0∼1.5wt% phytic acid were applied respectively, to the arm skins of 45 Asian women 20'-40's for 7 weeks. Improvement on moisture was evaluated. In addition, improvements on sebum, elasticity, and wrinkle were examined after applying placebo, Inositol and phytic acid-containing skin lotions for face, respectively. For 1.0 wt% inositol resulted in 19% increase of moisture. The wrinkle reduction and elasticity improved 12.4% and 17.0% on average, respectively. Applying 0.5wt% phytic acid resulted in 71.6% increase the moisture. Improvements on wrinkle and elasticity were 15.9% and 21.9% respectively. Applying inositol or phytic acid regardless of dry or oily, resulted in sebum value recovery to that of the normal skin after 2- 4 weeks. Inositol is inferior to phytic acid in improvenients of the skin, and phytic acid is not suitable to sensitive skin. So 0-0.5wt% of phytic acid were added to 1.0wt% inositol and similar experiments were carried out. In case of added 0.1wt% phytic acid, moisture increased 63.8% approximately. Improvements on elasticity and reduction on wrinkle were 17.2% and 17.4%, respectively. Both skin types were turned to normal skin type after 2 weeks. It could improve the skin condition when used inositol added phytic acid. The optimized concentration of phytic acid was 0.10wt% with 1.0wt% of inositol for synergic effect.

• 동의생리병리학회지
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• 제20권6호
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• pp.1561-1566
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• 2006

Sebum is secreted due to the effect of androgen, which start to be secreted at puberty. Androgens have profound effects on the physiology of the sebaceous gland, Using the human sebocyte cell line SZ95, we investigated the inhibitory effect of Chelidonii Harba (CH) on the subum production. Our results showed that numerous cytoplasmic lipid droplets were examined by Oil red staining and lipid droplets were increased markedly by testosterone. Cell viability was dose-dependently decreased by CH as compared with untreated cells, while total lipid content and cholesterol slightly were increased by CH. Testosterone significantly stimulated the synthesis of total lipid and the synthesis of specific sebaceous lipids such as cholesterol and triglyceride. Combined treatment with CH and testosterone resulted in a lower lipid synthesis than with testosterone alone. Especially cholesteol content was reduced by combined treatment with CH and testosterone. These results indicate that CH inhibits the testosterone-induced lipid synthesis in SZ95 cells and acts antagonistically to androgen at the cellular level.

• 한국전통의학지
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• 제15권1호
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• pp.77-82
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• 2006

Lavandula vera is indispensable member of the herb family, used for perfumes and potpourri. Androgens have profound effects on the physiology of the sebaceous gland. Sebum is secreted due to the effect of androgen, which starts to be secreted at puberty. Using the human sebocyte cell line SZ95. the author investigated the inhibitory effect of Lavandula vera on the lipid production. Light microscopic finding were examined numerous cytoplasmic lipid droplets SZ95 cells by Oil red staining and lipid droplets were increased markedly by testosterone. On the other hand, combined treatment with Lavandula vera and testosterone resulted in a lower lipid droplets than with testosterone alone in a dose-dependent manner. These findings indicate that Lavandula vera acts antagonistically to testosterone and inhibits the lipid synthesis of SZ95 cells at the cellular level.

• 대한한방부인과학회지
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• 제25권4호
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• pp.46-55
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• 2012

Objectives: It is well known that genetic factors and environmental factors play major role in aging skin. In general, son and daughter take after their parents in appearance. But comparability of skin properties in Korean family has not been well estimated. So we evaluated the correlation of skin properties in Korean mother-daughter pairs. Methods: 10 couples of mother and daughter pair(n=20) participate in this study. Mothers and daughters were aged $50.6{\pm}2.459$ and $23.8{\pm}2.15$ years, respectively. Skin moisture, sebum, skin color and elasticity is measured using non-invasive method : Corneometer CM825, Sebumeter(MPA580), Mexameter MX18, Cutometer MPA580. Statistical analysis program we used is Minitab 14 Korea. Results: The Skin moisture of mother group was significantly higher than daughter group. And skin elasticity(R2) of the daughter group was significantly higher than mother group. In the results of correlation analysis between mother and daughter pairs, skin elasticity(R2) had high positive correlation(r=0.729, p=0.026). But skin moisture, sebum, melanin index, erythema index and skin elasticity(R5) did not be confirmed a significant correlation. Conclusions: Skin elasticity(R2) is the only factor that showed high positive correlation significantly in mother and daughter pairs. Mother and daughter share the genetic factors and environmental factors that influence skin aging. So, mother's aging pattern will be a good guide for anti-aging of daughters.

• 한국콘텐츠학회논문지
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• 제21권9호
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• pp.742-749
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• 2021

본 연구에서는 60대 여성들을 대상으로 시트 마스크의 사용빈도에 따른 피부상태 변화를 비교 분석하고자 하였다. 2020년 5월 1일부터 2020년 6월 3일까지 5주간 실험을 진행하였으며, 연구의 목적을 이해하고 실험에 대한 서면동의를 받은 60대 여성 70명을 선정하였다. 본 연구의 실증분석은 모두 유의수준 5%에서 검증하였으며, 통계처리는 SPSS WIN 21.0 프로그램을 사용하여 분석하였다. 수분 증가와 거칠기 감소, 유분 증가 및 색소의 감소가 시트 마스크를 주 7회 적용한 그룹에서 효과가 있는 것으로 나타나 피부에 자극을 주지 않는 범위 내에서 시트 마스크의 사용빈도가 높을수록 피부상태에 긍정적 영향을 주는 것으로 나타났다. 향후 피부 유형별 체계적인 측정과 개선을 시도하는 노력의 효과를 증대시키는데 기여할 것이며, 피부상태에 영향을 미치는 요인을 규명하기 위해 식습관이나 생활습관 영향, 유전적 영향, 생활환경 등을 살펴보고 요인별 비교가 필요할 것으로 사료된다.

• 대한본초학회지
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• 제24권1호
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• pp.133-139
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• 2009

Objectives : This study was designed to investigate the effects of alcoholic fermentation extract from ovary and rind of pear on human skin. Methods : We investigated the effects of samples on human skin in terms of clinical trial. 32 of healthy volunteers, who lived in mokpo participated in clinical trial. Effects of sample on hygroscopicity and water-holding capacity were investigated. Sebum, moisture, scabrousness and desquamation were also investigated. Facial massages were conducted 8 times in each volunteers. Results : Single treatment group showed elevated levels of hygroscopicity (Normal : 106.4$\pm$2.1%, vs Pear : 114.1$\pm$6.2) and water-holding capacity (Normal : 87.1$\pm$4.4%, vs Pear : 96.2$\pm$1.3) on forearm of 16 volunteers respectively. In addition, massage group using sample showed elevated moisture (Control : 3.8$\pm$5.8%, vs Sample : 15.2$\pm$4.7%) and lowered scabrousness levels (Control : -12.3$\pm$4.4%, vs Sample : -22.0$\pm$5.2%) significantly. However, the levels of sebum did not affected by sample. Conclusions : These result suggest that alcoholic fermentation extract from ovary and rind of pear has moisturizing effect on human skin.