• Bulletin of the Korean Chemical Society
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• 제35권7호
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• pp.1956-1964
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• 2014

To provide the scientific corroboration of the traditional uses of Akebia quinata (Thunb.) Decne., a detailed analytical examination of A. quinata stems was carried out using a reversed-phase high performance liquid chromatography (RP-HPLC) method coupled to photodiode array detector (PDA) for the simultaneous determination of four phenolic substances; cuneataside D (1), 2-(3,4-dihydroxyphenyl)ethyl-O-${\beta}$-D-glucopyranoside (2), 3-caffeoylquinic acid (3) and calceolarioside B (4). Particular attention was focused on the main compound, 3-caffeoylquinic acid (3), which has a range of biological functions. In addition, 2-(3,4-dihydroxyphenyl)ethyl-O-${\beta}$-D-glucopyranoside (2) was considered as a discernible marker of A. quinata from its easy confuse plants. The contents of compounds 2 and 3 ranged from 0.72 to 2.68 mg/g and from 1.66 to 5.64 mg/g, respectively. The validation data indicated that this HPLC/PDA assay was used successfully to quantify the four phenolic compounds in A. quinata from different locations using relatively simple conditions and procedures. The pattern-recognition analysis data from 53 samples classified them into two groups, allowing discrimination between A. quinata and comparable herbs. The results suggest that the established HPLC/PDA method is suitable for quantitation and pattern-recognition analyses for a quality evaluation of this medicinal herb.

• 한국문헌정보학회지
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• 제30권4호
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• pp.129-149
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• 1996

학문으로서의 문헌정보학은 1930년대부터 사회과학(또는 응용사회과학)의 한 분야로 출발하였다. 그러나 실무와 기술을 강조하는 기능 주의적 입장으로 인해 문헌정보학의 사회과학성은 점차 상실되었고, 대신 과학기술적인 입장이 강조되었다. 결국 문헌정보학은 주된 연구대상인 도서관과 그 관련기관을 사회적 지식체계로 파악하지 못하였으며, 사회과학적 이론과 철학을 도입하는 데도 소홀할 수밖에 업었다. 그러므로 이 연구에서는 현 단계 문헌정보학의 학문성에 대한 인식론적 전환을 위하여 도서관사회학이라는 연구영역을 시론 적으로 제시하려고 하였다. 이것은 문헌정보학의 본질을 사회과학에서 파악한 것으로서 그것을 뒷받침해 줄 수 있는 대표적인 인식론으로서 사회인식론과 지식사회학을 제시하고 이를 토대로 도서관사회학이라는 새로운 연구영역을 시론 적으로 모색하게 되었다.

• 대한한방소아과학회지
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• 제22권1호
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• pp.49-57
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• 2008

Objectives As children are physiologically and pathologically sensitive and likely to have trouble developing respiratory and the digestive system, it is necessary for them to improve and adapt to their digestive and respiratory capacity slowly. Although they desperately need to practice Healthcare Qi Gong as they get older, few studies have been conducted about that. While collecting materials on child Healthcare Qi Gong, In order to study more about Dan Dong Ten Lessons, medical researchers and children's parent should be more concerned to these studies. The purpose of this study was to understand Dan Dong Ten Lessons through research on children's healthcare Qi Gong. Methods This study was prepared through collecting data from past oriental medicine studies. Through the examination of Chinese medicine books and scientific studies about Dan Dong Ten Lessons and healthcare Qi Gong, Dan Dong Ten Lessons was classified and systemized. Results Dan Dong Exercise among the contents of children's healthcare Qi Gong was classified through the classification and theorization of Dan Dong Ten Lessons, although the classification and development of children's Qi Gong methods should have been carried out in the area of korean medicine, but it was not easy to find the references. Conclusions Dan Dong Ten Lessons is a song and Qi Gong therapy for children. It also teaches children how to live their life, guides them in the right direction for their life. Therefore, it should be developed academically and practically, so that it can pass down to the next generation as traditional heritage.

• Journal of Korean Neurosurgical Society
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• 제39권2호
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• pp.130-135
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• 2006

Objective : After ischemic stroke, partial recovery of function frequently occurs and may depend on the plasticity of axonal connections. Here, we examine whether blockade of the Nogo/NogoReceptor[NgR] pathway might enhance axonal sprouting and thereby recovery after focal brain infarction. Methods : Adult male Sprague Dawley rats weighing $250{\sim}350g$ were used. Left middle cerebral artery occlusion[MCAO] was induced with a intraluminal filament. An osmotic mini pump [Alzet 2ML4, Alza Scientific Products, Palo Alto, CA] for the infusion of NgR-Ecto[310]-Fc to block Nogo/NgR pathway was implanted 1 week after cerebral ischemia. Prior to induction of ischemia, all animals received training in the staircase and rotarod test. Two weeks after biotin dextran amine injection, animals were perfused transcardially with PBS, followed by 4% paraformadehyde/PBS solution. Brain and cervical spinal cord were dissected. Eight coronal sections spaced at 1mm intervals throughout the forebrain of each animal with cresyl violet acetate for determination of infarction size. Images of each section were digitized and the infarct area per section was measured with image analysis software. Results : Histological examination at 11 weeks post-MCAO demonstrates reproducible stroke lesions and no significant difference in the size of the stroke between the NgR[310]Ecto-Fc protein treated group and the control group. Behavioral recovery is significantly better and more rapid in the NgR-Ecto[310]-Fe treated group. Blockade of NgR enhances axonal sprouting from the uninjured cerebral cortex and improves the return of motor task performance. Conclusion : Pharmacological interruption of NgR allows a greater degree of axonal plasticity in response this is associated with improved functional recovery of complicated motor tasks.

• Journal of Nutrition and Health
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• 제42권2호
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• pp.189-196
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• 2009

The purposes of this study were to establish the scope of population groups to be set and nutrients to be included for Codex Nutrient Reference Values (NRVs). Examination of a variety of documents and reports on the principles of scientific evidence was gone through to choose representative groups from a variety of population groups and kinds of nutrients for setting Codex NRVs. Also, hearings from the groups of NRVs expertise has been formed and was gone through by e-working process. The differences of food and foods being consumed in general and by specific population groups and limited actual space on packages for food labeling were considered. This paper suggest the options on the scope of population groups to be set and nutrients to be included for Codex NRVs on the basis of the above procedures. Also, the advantages and disadvantages of these options are commented when the options are applied for establishment and revision of the Codex NRVs.

• 보존과학회지
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• 제27권4호
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• pp.451-458
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• 2011

이 연구에서는 문헌조사와 광학적 및 과학적 분석조사를 토대로 송산리 6호분 벽화의 제작기법에 대해 고찰하였다. 연구결과, 송산리 6호분의 전축방식은 공적법이 아닌 모르타르를 이용하여 전(塼)을 축조하였고 줄눈(masonry joint) 재료로 석회, 모래 및 석고를 이용하였다. 전돌 표면에는 전체적으로 흑색을 칠한 다음 백색 회(灰)칠을 하였다. 그 위에 벽화제작을 위한 점토 바탕 층을 조성하였는데 수비가 잘된 점토를 흙손 등의 도구를 이용하지 않고 붓으로 바르듯이 완성하였다. 바탕층에 사용된 점토의 재료적 특성은 $30{\mu}m$ 실트질 크기 이하의 광물입자들로 구성되어 있다. 현재까지 고대의 고분벽화에서 사신도의 채색 부위에만 점토 바탕층을 조성하여 제작된 고분벽화는 송산리 6호분이 유일하다. 이 송산리 6호분은 동양을 비롯한 한국의 다른 벽화에서 볼 수 없는 제작기술이라 할 수 있으며 1933년 발굴 당시에 벽화는 이미 심각하게 훼손된 상태였다고 가정하더라도 종합적으로 볼 때 미완의 벽화라고 추정할 수 있다.

• 대한치과보철학회지
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• 제42권5호
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• pp.544-555
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• 2004

Statement of problem: Shade selection has traditionally been accomplished by visual examination, which is particularly relevant to the shade selection of anterior teeth, but the subjective nature of visual analysis can lead to errors in shade matching. Recently shade selection systems have been developed to provide a more objective and scientific approach to understanding and clarifying shade selection. Purpose : The purpose of this study was analysis of various shade analyzing equipment with the goal of providing a more objective shade selection. Materials and method: Visual shade matching system selection(Vita Lumin Vacuum shade guide, Vitapan 3D Master shade guide) and mechanical shade matching method($ShadeEye^{(R)}$-EX Chroma Meter, $Shadescan^{TM}$ System) used for this study. The shade guide tap specimens for 10 extracted maxillary anterior teeth were produced by selecting shades using each shade matching system. The accuracy of the selection of shades for the teeth and fabricated specimens were evaluated by analyzing the calculated shade difference(${\Delta}E^*$), using a spectrophotometer and calculating the output of value $L^*,\;a^*,\;b^*$. Results and conclusion: The results show that the average ${\{Delta}E^*$ value (difference of shade) of the shade tap specimens to the actual specimen decreased in the following order: Vita Lumin Vacuum Shade Guide(VL), $ShadeEye^{(R)}$-EX Chroma Meter(SE) Vitapan 3D Master Shade guide(V3), and $Shadescan^{TM}$ System(55) : and that there are significant statistical differences between the VL and SS (p<0.05). In the analysis of the ${\Delta}E^*$ (difference of shade) value,40% of the VL group was found to be less than 3.3 (limit value of shade tap specimens clinically acceptable), 60% in the V3 group, 50% in the SE group, and 80% in the SS group.

• 한국재료학회지
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• 제30권9호
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• pp.453-457
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• 2020

Tomb No. 1 (Donghachong) of the Buyeo Neungsan-ri Tomb complex (listed as UNESCO World Heritage Site), is a royal tomb of the Baekje Sabi Period. One wooden coffin unearthed there is an important relic of the funerary culture of the Baekje. This study examines the production techniques of gilt-bronze objects attached to the wooden coffin excavated from Donghachong. The base metal of the gilt-bronze object is pure copper, with single α phase crystals in a heterogeneous form containing annealing twins; Au and Hg are detected in the gilt layer. We suggest that the surface of the forging copperplate is gilded using a mercury amalgam technique; it is thought that the annealing twins of the base material formed during the heat treatment process for the sheet metal. The gilt layer is three to five times thicker for the gilt-bronze objects found near the foot of the coffin than those near the head. We estimate the plating process is carried out at least three times because three layers are identified on the plate near the head. Therefore, it is likely that the materials and methods used to construct the gilt-bronze objects found in different parts of the coffin are the same, but the number of platings is different. This research confirms the metal crafting techniques used in Baekje by the examination of production techniques of these gilt-bronze objects. Further, our paper presents an important example of restoration and reconstruction for a museum exhibition, through effective use of scientific analysis and investigation.

• 산업경영시스템학회지
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• 제22권51호
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• pp.175-187
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• 1999

The notion of productivity has been extended from the quantitative change of input factors to the efficiency change meaning efficient use of resources, and to the technical change meaning the qualitative improvement of input resources. In this way, the technical change is termed as total factor productivity in the individual businesses or the manufacturing industries. They should efficiently respond to the variations of economic environment and at the same time, have to make the efforts to improve productivity by increasing managerial efficiency and rasing the level of technology change for the continuous growth. Considering the growing importance of productivity, this study closely examines the factors influctuation on the productivity, fluctuation using total factor productivity in korean manufacturing industries. For the objective this study investigates the methods of measurement about total factor productivity, establishes the hypotheses based on the preceding research and finding. The results are obtained through the examination on the outcoms of regression analysis and related data. The results can be summarized as follows, First, in the progress of korean industrialization, the qualitative growth does not depend on the total factor productivity of the technical advance, and does not lead to the industry expansion. That is, the contribution of total factor productivity turns out to be relatively low. Second, it is necessary for the manufacturing industry to improve the level of technology and to emphasize the innovation of business, since the capital investment does not completely become fixed in the growth rate of productivity. Finally, continuous R&D investment should be made to increase total factor productivity. Namely, the regulation of industrial structure with an intensive technical development is essential and should be based on scientific and technical knowledge.

• 한국축산식품학회지
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• 제35권5호
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• pp.674-682
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• 2015

The objective of this study was to evaluate the risk of illness from Campylobacter spp. on ham. To identify the hazards of Campylobacter spp. on ham, the general characteristics and microbial criteria for Campylobacter spp., and campylobacteriosis outbreaks were investigated. In the exposure assessment, the prevalence of Campylobacter spp. on ham was evaluated, and the probabilistic distributions for the temperature of ham surfaces in retail markets and home refrigerators were prepared. In addition, the raw data from the Korea National Health and Nutrition Examination Survey (KNHNES) 2012 were used to estimate the consumption amount and frequency of ham. In the hazard characterization, the Beta-Poisson model for Campylobacter spp. infection was used. For risk characterization, a simulation model was developed using the collected data, and the risk of Campylobacter spp. on ham was estimated with @RISK. The Campylobacter spp. cell counts on ham samples were below the detection limit (<0.70 Log CFU/g). The daily consumption of ham was 23.93 g per person, and the consumption frequency was 11.57%. The simulated mean value of the initial contamination level of Campylobacter spp. on ham was −3.95 Log CFU/g, and the mean value of ham for probable risk per person per day was 2.20×10⁻¹². It is considered that the risk of foodborne illness for Campylobacter spp. was low. Furthermore, these results indicate that the microbial risk assessment of Campylobacter spp. in this study should be useful in providing scientific evidence to set up the criteria of Campylobacter spp..