• Proceedings of the Korean Society for Bioinformatics Conference
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• 2003.10a
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• pp.17-25
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• 2003

Determining the binding sites in protein-nucleic acid complexes is essential to the complete understanding of protein-nucleic acid interactions and to the development of new drugs. We have developed a set of algorithms for analyzing protein-nucleic acid interactions and for predicting potential binding sites in protein-nucleic acid complexes. The algorithms were used to analyze the hydrogen-bonding interactions in protein-RNA and protein-DNA complexes. The analysis was done both at the atomic and residue level, and discovered several interesting interaction patterns and differences between the two types of nucleic acids. The interaction patterns were used for predicting potential binding sites in new protein-RNA complexes.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2002.07b
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• pp.739-742
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• 2002

This paper described on the fabrication of microstructures by DRIE(deep reactive ion etching). SOI(Si-on-insulator) electric devices with buried cavities are fabricated by SDB technology and electrochemical etch-stop. The cavity was fabricated the upper handling wafer by Si anisotropic etch technique. SDB process was performed to seal the fabricated cavity under vacuum condition at -760 mmHg. In the SDB process, captured air and moisture inside of the cavities were removed by making channels towards outside. After annealing($1000^{\circ}C$, 60 min.), The SDB SOI structure was thinned by electrochemical etch-stop. Finally, it was fabricated microstructures by DRIE as well as an accurate thickness control and a good flatness.

• Journal of the Korean Society for Precision Engineering
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• v.18 no.9
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• pp.140-146
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• 2001

Seals in a universal joint bearing are important components reinforcing lubrication performance by holding lubricant and preventing infiltration of dust, moisture, etc.. There is a great difference in seal performance according to seal shape and bonding position. Therefore, in this study, as for both the lip type seal and the O-ring type seal, FE analysis is conducted using Mooned-Rivlin Model. The results show that O-ring type seal does not have any effect of misalignment angle compared with lib type seal, which is more profitable.

• Journal of Dental Rehabilitation and Applied Science
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• v.19 no.1
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• pp.35-41
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• 2003

With the understanding of tooth crown biomechanics and the progress of dentin adhesives, bonded porcelain restorations including a porcelain laminate veneer present an extended spectrum of indications for anterior teeth. Porcelain laminate veneer as a restoration offers the conservative solution that balances the functional and esthetic needs of the anterior dentition. Porcelain's stiffness, its surface characteristics, and the biomechanical strength achieved through bonding to tooth surface enable the restoration of the tooth as a whole supporting occlusal force and masticatory function. Namely, the optical effects inherent in the tooth and the lifelike features of the porcelain make that this restoration approaches the ultimate in esthetic satisfaction for both the dentist and the patient. A 49-year-old female patient with the incisal discoloration of upper central incisors and black triangle between the central incisors was referred to correct her esthetic problems with prosthodontic approach. The patient was satisfied with two porcelain laminate veneers that were made according to prof. Magne and Belser's recommendation.

• Molecular & Cellular Toxicology
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• v.2 no.4
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• pp.279-284
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• 2006

This paper describes the fabrication methods of a carbon nanotube (CNT) filter and a microdialysis chip. A CNT filter can help perform dialysis on a microfluidic chip. In this study, a membrane type of a CNT filter is fabricated and located in a microfluidic chip. The filter plays a role of a dialysis membrane in a microfluidic chip. In the fabrication process of a CNT filter, individual CNTs are entangled each other by amide bonding that is catalyzed by 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and N-hydroxysuccinimide (NHS). The chemically treated CNTs are shaped to form a CNT filter using a PDMS film-mold and vacuum filtering. Then, the CNT filter is sandwiched between PDMS substrates, and they are bonded together using a thin layer of PDMS prepolymer as adhesive. The PDMS substrates are fabricated to have a microchannel by standard photo-lithography technique.

• Proceedings of the KIPE Conference
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• 2006.06a
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• pp.532-533
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• 2006

In this research work attempts were made to study the bonding of thermoplastics with adhesives using solar energy. In order to study the curing behaviour necessary experiments were conducted under varying conditions of temperature, exposure time and power. The cured samples were then studied under the optical microscope before subjecting to tensile testing in order to study their mechanical properties. The fracture surfaces were further studied under the Scanning Electron Microscopy in order to study the microstructural changes that are taken place during curing. From the present study it is evident that curing under higher solar energy temperature, generally improves bond strength and quality of the adhesive joints when compared to other modes of curing process expect the microwave curing process.

• KSBB Journal
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• v.27 no.5
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• pp.273-280
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• 2012

Graphene is a one-atom-thick sheet composed of carbon atoms only. It has a two-dimensional honeycomb structure with $sp^2$ orbital bonding, which presents some unique properties. Due to large Young's modulus, good electrical conductivity, ability to immobilize several kinds of small molecules and proteins, and biocompatibility of graphene, it has attracted interests inits ability to enhance cell growth and differentiation, followed by recent several studies. We reviewed about the osteogenic differentiation of mesenchymal stem cells, and neurogenic differentiation of neuron stem cells, and the ectodermal and mesodermal differentiation of induced pluripotent stem cells using graphene. Graphene has not only enhanced the adhesion and proliferation of mesenchymal stem cells, but also led to the faster differentiation even without any other exogenous signals. Nonetheless, graphene has some cytotoxicities in its amount-response manner, which is critical to regenerative medicine. The cytotoxicities of graphene were compared with those of grapheneoxide and carbon nanotubes.

• Proceedings of the KACD Conference
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• 2001.11a
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• pp.586.1-586
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• 2001

Large butt-joint box typed class II cavites with cervical margins 1mm below the cemento-enamel junction were cut into 70 extracted human molars. The cavities(7 groups, n=10) were filled using a closed/open sandwich restoration or total bond restoration technique with materials according to the manufacturer's recommandation using the single-component bonding agent for each system. Teeth were thermocycled 500 times between $5^{\circ}C$ and $55^{\circ}C$ with 30-second dwell times.(omitted)

• Textile Coloration and Finishing
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• v.21 no.4
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• pp.57-62
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• 2009

N-Halamines are compounds which have covalent bonding between nitrogen and halogen. N-Halamine materials possess strong antimicrobial properties against wide spectrum of bacteria. The aim of this study is to prepare N-halamine membranes using m-aramid and poly(vinyl alcohol) (PVA). Surface characteristics using scanning electron microscope (SEM), pore size distribution, liquid permeability and mean pore size were measured to confirm feasibility as membrane. The results indicated that increased PYA portion up to 15% in the m-aramid/PVA blend resulted in improved pore size distribution, liquid permeability as well as mean pore size. Furthermore, antibacterial efficacy of the membranes after chlorination was confirmed and the results showed that bacteria in water were inactivated.

• Journal of Sensor Science and Technology
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• v.13 no.3
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• pp.175-181
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• 2004

A pressure sensor for high temperature was fabricated by using a SDB(Silicon-Direct-Bonding) wafer with a Si/$SiO_{2}$/ Si structure. High pressure sensitivity was shown from the sensor using a single crystal silicon of the first layer as a piezoresistive layer. It also was made feasible to use under the high temperature as of over $120^{\circ}C$, which is generally known as the critical temperature for the general silicon sensor, by isolating the piezoresistive layer dielectrically and thermally from the silicon substrate with a silicon dioxide layer of the second layer. The pressure sensor fabricated in this research showed very high sensitivity as of $183.6{\mu}V/V{\cdot}kPa$, and its characteristics also showed an excellent linearity with low hysteresis. This sensor was usable up to the high temperature range of $300^{\circ}C$.