• Title/Summary/Keyword: scale-up technology

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Removal of iron scale from feed-water in thermal power plant by magnetic separation - Introduction to chemical cleaning line -

  • Yamamoto, Junya;Mori, Tatsuya;Hiramatsu, Mami;Akiyama, Yoko;Okada, Hidehiko;Hirota, Noriyuki;Matsuura, Hideki;Namba, Seitoku;Sekine, Tomokazu;Mishima, Fumihito;Nishijim, Sigehiro
    • Progress in Superconductivity and Cryogenics
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    • v.20 no.2
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    • pp.6-10
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    • 2018
  • Removal of iron oxide scale from feed-water in thermal power plant can improve power generation efficiency. We have proposed a novel scale removal system utilizing High Gradient Magnetic Separation (HGMS). This system can be applied to high temperature and pressure area. We have conducted the lab-scale model experiments using ${\varphi}50mm$ filters and it demonstrated high removal efficiency in HGMS, but scale-up of the system is required toward practical use. In this study, we conducted a large scale mock-up HGMS experiment. We used the superconducting solenoidal magnet with ${\varphi}400mm$ bore and demonstrated that our HGMS system can achieve sufficient scale removal capacity that is required to introduce into both off-line and on-line system.

5kg $U_3O_8$/Batch Scale Mock-up Test for the Electrochemical Reduction of Spent Oxide Fuel (사용후핵연료의 전기화학적 금속전환을 위한 5kg $U_3O_8$/Batch 규모의 Mock-up시험)

  • 오승철;허진목;홍순석;이원경;서중석;박성원
    • Proceedings of the Korean Radioactive Waste Society Conference
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    • 2003.11a
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    • pp.358-362
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    • 2003
  • An electrochemical reduction technology which can reduce the decay heat, volume, and radioactivity of spent fuel by a factor of quarter by converting oxide type spent fuel to a metallic form in a molten salt was developed and mock-up test in a 5kg $U_3O_8$/batch scale was carried out. The electrochemical reaction was analyzed regarding the operational factors. The research efforts was also concentrated on the apparatus development for a hot test. Fresh $U_3O_8$ powder was metallized with a more than 99% yield via this electrochemical technology and design data for the 20kg $U_3O_8$/batch scale apparatus were also obtained.

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Mass Production of Paclitaxel by Plant Cell Culture (식물세포배양에 의한 항암제 Paclitaxel의 대랑 생산)

  • CHOI Hyung-Kyoon;SON Joo-Sun;NA Gwang-Hwee;HONG Seung-Suh;SONG Jai-Young
    • Proceedings of the Korean Society of Plant Biotechnology Conference
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    • 2002.04a
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    • pp.27-31
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    • 2002
  • Samyang Genex succeeded in commercialization of anticancer agent-paclitaxel by plant cell culture technology. The core technology of Samyang Genex relating paclitaxel production includes cell line development, cell line preservation, cell culture, scale-up technology, and purification technology. On the basis of the research, Samyang Genex built the factory operated by CGMP (current good manufacturing practice). The $paclitaxel-Genexol^{TM}$ is commercially available in Korea, and it will be launched to world market including USA after approval US FDA.

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Mass Production of Paclitaxel by Plant Cell Culture (식물세포배양에 의한 항암제 Paclitaxel의 대량 생산)

  • Choi, Hyung-Kyoon;Son, Joo-Sun;Na, Gwang-Hee;Hong, Seung-Suh;Song, Jai-Young
    • Proceedings of the Korean Society of Plant Biotechnology Conference
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    • 2002.04b
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    • pp.27-31
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    • 2002
  • Samyang Genex succeeded in commercialization of anticancer agent-paclitaxel by plant cell culture technology. The core technology of Samyang Genex relating paclitaxel production includes cell line development, cell line preservation, cell culture, scale-up technology, and purification technology. On the basis of the research, Samyang Genex built the factory operated by CGMP (current good manufacturing practice). The $paclitaxel-Cenexol^{TH}-is$ commercially available in Korea, and it will be launched to world market including USA after approval of US FDA.

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Mass Production of Paclitaxel by Plant Cell Culture (식물세포배양에 의한 항암제 Paclitaxel의 대량 생산)

  • Choi, Hyung-Kyoon;Son, Joo-Sun;Na, Gwang-Hwee;Hong, Seung-Suh;Park, Yeon-Seung;Song, Jai-Young
    • Journal of Plant Biotechnology
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    • v.29 no.1
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    • pp.59-62
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    • 2002
  • Samyang Genex succeeded in commercialization of anticancer agent-paclitaxel by plant cell culture technology. The core technology of Samyang Genex relating paclitaxel production includes cell line development, cell line preservation, cell culture, scale-up technology, and purification technology. On the basis of the research, Samyang Genex built the factory operated by CGMP (current good manufacturing practice). The paclitaxel-Genexol$^{TM}$-is commercially available in Korea, and it will be launched to world market including USA after approval of US FDA.

Comparative Analysis of the Performance of SIFT and SURF (SIFT 와 SURF 알고리즘의 성능적 비교 분석)

  • Lee, Yong-Hwan;Park, Je-Ho;Kim, Youngseop
    • Journal of the Semiconductor & Display Technology
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    • v.12 no.3
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    • pp.59-64
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    • 2013
  • Accurate and robust image registration is important task in many applications such as image retrieval and computer vision. To perform the image registration, essential required steps are needed in the process: feature detection, extraction, matching, and reconstruction of image. In the process of these function, feature extraction not only plays a key role, but also have a big effect on its performance. There are two representative algorithms for extracting image features, which are scale invariant feature transform (SIFT) and speeded up robust feature (SURF). In this paper, we present and evaluate two methods, focusing on comparative analysis of the performance. Experiments for accurate and robust feature detection are shown on various environments such like scale changes, rotation and affine transformation. Experimental trials revealed that SURF algorithm exhibited a significant result in both extracting feature points and matching time, compared to SIFT method.

Application of Scale-Up Criterion of Constant Oxygen Mass Transfer Coefficient ($k_La$) for Production of Itaconic Acid in a 50 L Pilot-Scale Fermentor by Fungal Cells of Aspergillus terreus

  • Shin, Woo-Shik;Lee, Dohoon;Kim, Sangyong;Jeong, Yong-Seob;Chun, Gie-Taek
    • Journal of Microbiology and Biotechnology
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    • v.23 no.10
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    • pp.1445-1453
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    • 2013
  • The scale-up criterion of constant oxygen mass transfer coefficient ($k_La$) was applied for the production of itaconic acid (IA) in a 50 L pilot-scale fermentor by the fungal cells of Aspergillus terreus. Various operating conditions were examined to collect as many $k_La$ data as possible by adjusting the stirring speed and aeration rate in both 5 L and 50 L fermentor systems. In the fermentations performed with the 5 L fermentor, the highest IA production was obtained under the operating conditions of 200 rpm and 1.5 vvm. Accordingly, we intended to find out parallel agitation and aeration rates in the 50 L fermentor system, under which the $k_La$ value measured was almost identical to that ($0.02sec^{-1}$) of the 5 L system. The conditions of 180 rpm and 0.5 vvm in the 50 L system turned out to be optimal for providing almost the same volumetric amount of dissolved oxygen (DO) into the fermentor, without causing shear damage to the producing cells due to excessive agitation. Practically identical fermentation physiologies were observed in both fermentations performed under those respective operating conditions, as demonstrated by nearly the same values of volumetric ($Q_p$) and specific ($q_p$) IA production rates, IA production yield ($Y_{p/s}$), and specific growth rate (${\mu}$). Specifically, the negligible difference of the specific growth rate (${\mu}$) between the two cultures (i.e., $0.029h^{-1}$ vs. $0.031h^{-1}$) was notable, considering the fact that ${\mu}$ normally has a significant influence on $q_p$ in the biosynthesis of secondary metabolites such as itaconic acid.

A Study on the Analysis of Management Efficiency of Start-up Investment Companies (창업투자회사의 경영 효율성 분석에 관한 연구)

  • Lee, Jun-Hyung;Yoon, Jun-Sang
    • Journal of Digital Convergence
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    • v.19 no.5
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    • pp.353-363
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    • 2021
  • This study analyzed to provide information for business improvement by analyzing the management efficiency of start-up investment companies so that startup investment companies can operate efficiently and by presenting information on inefficient factors. From 2014 to 2018, 83 start-up investment companies were analyzed using the DEA model. Input variables were he number of employees, capital, and output variables were selected for start-up investment assets, operating income, and net profit. As a result of the analysis, technical efficiency and pure technical efficiency showed a pattern with an increase in average, but scale efficiency repeatedly increased and decreased. It is believed that the decline in technology efficiency was due to the decrease in pure technology efficiency, and the inefficiency of start-up investment companies seems to have influenced the inefficiency of start-up investment companies rather than the inefficiency of scale. In addition, the size revenue shows that the DRS value is gradually decreasing, and the IRS value is generally increasing. It is believed that efficiency can be improved if operational inefficiency is improved based on the results and efficiency measures are established through scale expansion.

Depth-hybrid speeded-up robust features (DH-SURF) for real-time RGB-D SLAM

  • Lee, Donghwa;Kim, Hyungjin;Jung, Sungwook;Myung, Hyun
    • Advances in robotics research
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    • v.2 no.1
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    • pp.33-44
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    • 2018
  • This paper presents a novel feature detection algorithm called depth-hybrid speeded-up robust features (DH-SURF) augmented by depth information in the speeded-up robust features (SURF) algorithm. In the keypoint detection part of classical SURF, the standard deviation of the Gaussian kernel is varied for its scale-invariance property, resulting in increased computational complexity. We propose a keypoint detection method with less variation of the standard deviation by using depth data from a red-green-blue depth (RGB-D) sensor. Our approach maintains a scale-invariance property while reducing computation time. An RGB-D simultaneous localization and mapping (SLAM) system uses a feature extraction method and depth data concurrently; thus, the system is well-suited for showing the performance of the DH-SURF method. DH-SURF was implemented on a central processing unit (CPU) and a graphics processing unit (GPU), respectively, and was validated through the real-time RGB-D SLAM.

Multi-Valued Logic Device Technology; Overview, Status, and Its Future for Peta-Scale Information Density

  • Kim, Kyung Rok;Jeong, Jae Won;Choi, Young-Eun;Kim, Woo-Seok;Chang, Jiwon
    • Journal of Semiconductor Engineering
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    • v.1 no.1
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    • pp.57-63
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    • 2020
  • Complementary metal-oxide-semiconductor (CMOS) technology is now facing a power scaling limit to increase integration density. Since 1970s, multi-valued logic (MVL) has been considered as promising alternative to resolve power scaling challenge for increasing information density up to peta-scale level by reducing the system complexity. Over the past several decades, however, a power-scalable and mass-producible MVL technology has been absent so that MVL circuit and system implementation have been delayed. Recently, compact MVL device researches incorporating multiple-switching characteristics in a single device such as 2D heterojunction-based negative-differential resistance (NDR)/transconductance (NDT) devices and quantum-dot/superlattices-based constant intermediate current have been actively performed. Meanwhile, wafer-scale, energy-efficient and variation-tolerant ternary-CMOS (T-CMOS) technology has been demonstrated through commercial foundry. In this review paper, an overview for MVL development history including recent studies will be presented. Then, the status and its future research direction of MVL technology will be discussed focusing on the T-CMOS technology for peta-scale information processing in semiconductor chip.