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http://dx.doi.org/10.5010/JPB.2002.29.1.059

Mass Production of Paclitaxel by Plant Cell Culture  

Choi, Hyung-Kyoon (Samyang Genex Biotech Research Institute)
Son, Joo-Sun (Samyang Genex Biotech Research Institute)
Na, Gwang-Hwee (Samyang Genex Biotech Research Institute)
Hong, Seung-Suh (Samyang Genex Biotech Research Institute)
Park, Yeon-Seung (Samyang Genex Biotech Research Institute)
Song, Jai-Young (Samyang Genex Biotech Research Institute)
Publication Information
Journal of Plant Biotechnology / v.29, no.1, 2002 , pp. 59-62 More about this Journal
Abstract
Samyang Genex succeeded in commercialization of anticancer agent-paclitaxel by plant cell culture technology. The core technology of Samyang Genex relating paclitaxel production includes cell line development, cell line preservation, cell culture, scale-up technology, and purification technology. On the basis of the research, Samyang Genex built the factory operated by CGMP (current good manufacturing practice). The paclitaxel-Genexol$^{TM}$-is commercially available in Korea, and it will be launched to world market including USA after approval of US FDA.
Keywords
Cell line development; commercialization; $Genexol^{TM}$; plant cell culture; purification technology; scale-up technology;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
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