• Journal of Physiology & Pathology in Korean Medicine
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• v.32 no.1
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• pp.75-79
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• 2018

Animal models of atopic dermatitis (AD) are widely used to investigate therapeutic effects of candidates for AD. However, the characteristics of each model are not fully understood. This study was designed to compare the animal models of dermatitis induced by dinitrofluorobenzene (DNFB) and oxazolone (Ox). We investigated the effects of DNFB and Ox on skin thicknesses and weights as well as skin lesions associated with AD such as scale, crust and erythematous eruption, and histopathological changes such as hyperkeratosis, dermal and epidermal hyperplasia and immune cell infiltration in inflamed tissues. Multiple application of 0.5% Ox onto the skin increased skin thickness and weight compared to those of DNFB treated mice, as well as those of normal mice. In addition, topical application of DNFB induced marked scale, crust and erythematous eruption, while Ox induced erythematous eruption and mild scale and crust. Histopathological examination revealed that 0.5% Ox induced marked hyperplasia in the dermis and epidermis, large vesicles, spongiotic changes, mild hyperkeratosis and immune cell infiltration in balb/c mice. These data suggest that multiple applications of Ox can induce chronic AD like dermatitis in balb/c mice.

• The Journal of Fisheries Business Administration
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• v.44 no.1
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• pp.59-70
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• 2013

The purpose of this paper is to integrate various models of price formation and let the data choose the most proper model. After the data choose the proper model, one can analyze the price formation process and demand structures for fishery resources under the restriction of Korean fisheries regulations. This study suggests the integrated model including quasi-linear price formation model, Translog price formation model, AIDS price formation model and Lewbel price formation model as level variables. It also suggests another integrated model including AIDS price formation model, Rotterdam price formation model, Latinen-Theil price formation model and Neves price formation model as difference variables. The empirical results show that the AIDS price formation model is the most preferred in both level and difference variables of fishery resources. The estimated parameters show that all sample species have (-) sign of price flexibilities, thus following the law of demand. The scale flexibilities of all species are estimated as (-) sign, thus being adapted to the theory. The contribution and results are summarized as follows. First, the integrated model of fishery market demand has been developed and the data can choose the proper model without arbitrary choice of the researcher. Second, the fishery market demand structure could be analyzed in a way different from the ordinary demand analysis, which is based upon price flexibility and scale flexibility. Third, the integrated model for fishery resources can be used easily when catching restrictions are imposed by policies.

• New & Renewable Energy
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• v.5 no.4
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• pp.39-43
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• 2009

The variation of inflow at stream and hydrologic performance for small scale hydro power(SSHP) plants due to climate change have been studied. The model, which can predict flow duration characteristic of stream, was developed to analyze the variation of inflow caused from rainfall condition. And another model to predict hydrologic performance for SSHP plants is established. Monthly inflow data measured at Andong dam for 32 years were analyzed. The existing SSHP plant located in upstream of Andong dam was selected and analyzed hydrologic performance characteristics. The predicted results from the developed models show that the data were in good agreement with measured results of long term inflow at Andong dam and the existing SSHP plant. Inflow and ideal hydro power potential had increased greatly in recent years, however, these did not lead annual energy production increment of existing SSHP plant. As a results, it was found that the models represented in this study can be used to predict the primary design specifications and inflow of SSHP plants effectively.

• Computers and Concrete
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• v.24 no.4
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• pp.283-293
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• 2019

The limited availability of raw materials and increasing service demands for pavements pose a unique challenge in terms of pavement design and concrete material selection. The self-compacting rubberized concrete (SCRC) can be used in pavement design. The SCRC pavement slab has advantages of excellent toughness, anti-fatigue and convenient construction. On the premise of satisfying the strength, the SCRC can increase the ductility of pavement slab. The aim of this investigation is proposing a new method to predict the crack growth and flexural capacity of large-scale SCRC slabs. The mechanical properties of SCRC are obtained from experiments on small-scale SCRC specimens. With the increasing of the specimen depth, the bearing capacity of SCRC beams decreases at the same initial crack-depth ratio. By constructing extended finite element method (XFEM) models, crack growth and flexural capacity of large-scale SCRC slabs with different fracture types and force conditions can be predicted. Considering the diversity of fracture types and force conditions of the concrete pavement slab, the corresponding test was used to verify the reliability of the prediction model. The crack growth and flexural capacity of SCRC slabs can be obtained from XFEM models. It is convenient to conduct the experiment and can save cost.

• Journal of The Korean Astronomical Society
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• v.48 no.1
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• pp.57-66
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• 2015

Monte-Carlo radiative models of the diffuse Galactic light (DGL) in our Galaxy are calculated using the dust radiative transfer code MoCafe, which is three-dimensional and takes full account of multiple scattering. The code is recently updated to use a fast voxel traversal algorithm, which has dramatically increased the computing speed. The radiative transfer models are calculated with the generally accepted dust scale-height of 0.1 kpc. The stellar scale-heights are assumed to be 0.1 or 0.35 kpc, appropriate for far-ultraviolet (FUV) and optical wavelengths, respectively. The face-on optical depth, measured perpendicular to the Galactic plane, is also varied from 0.2 to 0.6, suitable to the optical to FUV wavelengths, respectively. We find that the DGL at high Galactic latitudes is mostly due to backward or large-angle scattering of starlight originating from the local stars within a radial distance of r < 0.5 kpc from the Earth. On the other hand, the DGL measured in the Galactic plane is mostly due to stars at a distance range that corresponds to an optical depth of $${\sim_\sim}$$ 1 measured from the Earth. Therefore, the low-latitude DGL at the FUV wavelength band would be mostly caused by the stars located at a distance of $r{\leq}0.5$ kpc and the optical DGL near the Galactic plane mainly originates from stars within a distance range of $1{\leq}r{\leq}2kpc$. We also calculate the radiative transfer models in a clumpy two-phase medium. The clumpy two-phase models provide lower intensities at high Galactic latitudes compared to the uniform density models, because of the lower effective optical depth in clumpy media. However, no significant difference in the intensity at the Galactic plane is found.

• Journal of Korean Society on Water Environment
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• v.24 no.1
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• pp.54-62
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• 2008

It is often believed that a more complex water quality model is better able to simulate reality. The more complex a model, however, the more parameters are involved thus increases the cost and uncertainty of modeling processes. The objective of this study was to compare the performance of two steady-state river water quality models, QUAL2E and QUAL-NIER, that have different complexity. QUAL-NIER is recently developed by National Institute of Environmental Research aiming to enhance the simulation capability of QUAL2E for eutrophic rivers. It is a carbon based model that considers different forms, such as dissolved versus particulate and labile versus refractory, of carbon and nutrients, and the contribution of autochthonous loading due to algal metabolism. The models were simultaneously applied to Nakdong River and their performance was evaluated by statistical verification with field data. Both models showed similar performance and satisfactorily replicated the longitudinal variations of BOD, T-N, T-P, Chl.a concentrations along the river. The algal blooms occurred at the stagnant reaches of downstream were also reasonably captured by the models. Although QUAL-NIER somewhat reduced the magnitude of errors, the hypothesis tests revealed no statistical evidence to justify its better performance. The contribution of autochthonous carbon and nutrient load by algal metabolism was insignificant because the hydraulic retention time is relatively short compare to the time scale of kinetic reactions. The results imply that the kinetic processes included in QUAL-NIER are too complex for the nature and scale of the real processes involved, thus needs to be optimized for improving the modeling efficiency.

• Journal of Soil and Groundwater Environment
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• v.22 no.6
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• pp.66-73
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• 2017

Empirical erosion models like Universal Soil Loss Equation (USLE) models have been widely used to make spatially distributed soil erosion vulnerability maps. Even if the models detect vulnerable sites relatively well utilizing big data related to climate, geography, geology, land use, etc within study domains, they do not adequately describe the physical process of soil erosion on the ground surface caused by rainfall or overland flow. In other words, such models are still powerful tools to distinguish the erosion-prone areas at large scale, but physics-based models are necessary to better analyze soil erosion and deposition as well as the eroded particle transport. In this study a physics-based soil erosion modeling system was developed to produce both runoff and sediment yield time series at watershed scale and reflect them in the erosion and deposition maps. The developed modeling system consists of 3 sub-systems: rainfall pre-processor, geography pre-processor, and main modeling processor. For modeling system validation, we applied the system for various erosion cases, in particular, rainfall-runoff-sediment yield simulation and estimation of probable maximum sediment (PMS) correlated with probable maximum rainfall (PMP). The system provided acceptable performances of both applications.

• Atmosphere
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• v.29 no.2
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• pp.131-147
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• 2019

On the urban scale, Micro-climate analysis models for urban scale have been developed to investigate the atmospheric characteristics in urban surface in detail and to predict the micro-climate change due to the changes in urban structure. BioCAS (Biometeorological Climate Impact Assessment System) is a system that combines such analysis models and has been implemented internally in the Korea Meteorological Administration. One of role in this system is the analysis of the health impact by heat waves in urban area. In this study, the vegetation cooling models A and B were developed and linked with BioCAS and evaluated by the temperature drop at the vegetation areas during ten selected heat-wave days. Smaller prediction errors were found as a result of applying the vegetation cooling models to the heat-wave days. In addition, it was found that the effects of the vegetation cooling models produced different results according to the distribution of vegetation area in land cover near each observation site - the improvement of the model performance on temperature analysis was different according to land use at each location. The model A was better fitted where the surrounding vegetation ratio was 50% or more, whereas the model B was better where the vegetation ratio was less than 50% (higher building and impervious areas). Through this study, it should be possible to select an appropriate vegetation cooling model according to its fraction coverage so that the temperature analysis around built-up areas would be improved.

• Wind and Structures
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• v.36 no.3
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• pp.161-174
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• 2023

The analytical model of tornado vortices plays an essential role in tornado wind description and tornado-resistant design of civil structures. However, there is still a lack of guidance for the selection and application of tornado analytical models since they are different from each other. For single-cell tornado vortices, this study conducts a comparative study on the velocity characteristics of the analytical models based on numerically simulated tornado-like vortices (TLV). The single-cell stage TLV is first generated by Large-eddy simulations (LES). The spatial distribution of the three-dimensional mean velocity of the typical analytical tornado models is then investigated by comparison to the TLV with different swirl ratios. Finally, key parameters are given as functions of swirl ratio for the direct application of analytical tornado models to generate full-scale tornado wind field. Results show that the height of the maximum radial mean velocity is more appropriate to be defined as the boundary layer thickness of the TLV than the height of the maximum tangential mean velocity. The TLV velocity within the boundary layer can be well estimated by the analytical model. Simple fitted results show that the full-scale maximum radial and tangential mean velocity increase linearly with the swirl ratio, while the radius and height corresponding to the position of these two velocities decrease non-linearly with the swirl ratio.

• Korean Journal of Health Education and Promotion
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• v.6 no.2
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• pp.23-39
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• 1989

There have been a lot of considerable. discussion and debate surrounding the management model in the health insurance management system and opinions regarding the management operating cost. It is a well known fact that there have always been dissenting opinions and debates surrounding the issue. The management operating cost varies according to the scale of the management organization and component members characteristics of the insurance carrier. Therefore, it is necessary to examine and compare the management operating cost to the simulated management models developed to cover those eligible for the health insurance scheme in this country. Since the management operating cost can vary according to the different models of management, four alternative management models have been established based on the critical evaluation of existing theories concerned, as well as on the basis of the survey results and simulation attempts. The first alternative model is the Unique Insurance Carrier Model(Ⅰ) ; desigened to cover all of the people with no classification of insurance qualifications and finances from the source of contribution of the insured, nationwide. The second is the Management Model of Large-scale District Insurance Carrier(Ⅱ) ; this means the Korean society would be divided into 21 large districts; each having its own insurance carrier that would cover the people in that particular district with no classification of insurance qualifications arid finances as in Model I. The third is the Management Model of Insurance Carrier Divided by Area and Classified with Occupation if Largescale (Ⅲ) ; to serve the self-employed in the 21 districts divided as in Model Ⅱ. It would serve the employees and their dependents by separate insurance carriers in large-scale similar to the area of the district-scale for the self-employed, so that the insurance qualifications and finances would be classified with each of the insurance carriers: The last is the Management Model of the Multi - insurance Carrier (Ⅳ) based on the Si. Gun. Gu area which will cover their own self- employed people in the area with more than 150 additional insurance carriers covering the employees and their dependents. The manpower necessary to provide services to all of the people according to the four models is calculated through simulation trials. It indicates that the Management Model of Large-scale District Insurance Carrier requires the most manpower among the four alternative models. The unit management operating costs per the insured individuals and covered persons are leveled with several intervals based on the insurance recipients. in their characteristics. The interval levels derived from the regression analysis reveal that the larger the scale of the insurance carriers is in the number of those insured and covered. the more the unit management operating cost decreases. significantly. Moreover. the result of the quadratic functional formula also shows the U-shape significantly. The management operating costs derived from the simulated calculation. on the basis of the average salary and related cost per staff- member of the Health Insurance Societies for Occupational Labours and Korean Medical Insurance Corporation for the Official Servants and Private School Teachers in 1987 fiscal year. show that the Model of Multi-insurance Carrier warrants the highest management operating cost. Meanwhile the least expensive management operating cost is the Management Model of Unique Insurance Carrier. Insurance Carrier Divided by Area and Classified with Occupation in Large-scale. and Large-scale District Insurance Carrier. in order. Therefore. it is feasible to select the Unique Insurance Carrier Model among the four alternatives from the viewpoint of the management operating cost and in the sense of the flexibility in promoting the productivity of manpower in the human services field. However. the choice of the management model for health insurance systems and its application should be examined further utilizing the operation research analysis for such areas as the administrative efficiency and factors related to computer cost etc.