• Journal of the Korean Statistical Society
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• 제29권2호
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• pp.201-217
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• 2000

The method of generalized estimating equations (GEE) has become very popular for the analysis of longitudinal data. We extend this work to the use of M-estimators; the resultant regression estimates are robust to heavy tailed errors and to outliers. The proposed method does not require correct specification of the dependence structure between observation, and allows for heterogeneity of the error. However, an estimate of the dependence structure may be incorporated, and if it is correct this guarantees a higher efficiency for the regression estimators. A goodness-of-fit test for checking the adequacy of the assumed M-estimation regression model is also provided. Simulation studies are conducted to show the finite-sample performance of the new methods. The proposed methods are applied to a real-life data set.

• 대한간호학회지
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• 제45권2호
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• pp.169-182
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• 2015

Purpose: This study was a meta-analysis designed to identify effects of Cognitive Behavioral Therapy (CBT) interventions in alleviating main symptoms of Attention Deficit Hyperactivity Disorder (ADHD) among school-aged children in Korea. Methods: Examination of several databases including Research Information Sharing Service, Korean Studies Information Service System, Data Base Periodical Information Academic and hand-searched article references, resulted in identification of 1,298 studies done between 2000 and 2013 of which 21 met the inclusion criteria. Comprehensive Meta-Analysis version 2.0 was used to analyze effect sizes, explore possible causes of heterogeneity, and check publication bias with a funnel plot and its trim-and-fill analysis. Results: Overall effect size of CBT intervention was large (g=1.08) along with each outcome of self-control (g=1.26), lack of attention (g=1.02), social skills (g=0.92), and hyperactivity (g=0.92). For heterogeneity, moderator analysis was performed, but no significant differences were found between the RCT (Randomized Controlled Trials) group and the NRCT (Non RCT) group. Also, meta-regression was performed using sample size, number of sessions, and length of session as predictors, but no statistically significant moderators were found. Finally, a funnel plot along with trim-and-fill analysis was produced to check for publication bias, but no significant bias was detected. Conclusion: Based on these findings, there is clear evidence that CBT intervention has significant positive effects on the main symptoms of school-aged children suffering ADHD. Further research is needed to target diverse age groups with ADHD along with more RCT studies to improve the effectiveness of the CBT intervention.

• Clinical and Experimental Pediatrics
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• 제63권2호
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• pp.34-43
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• 2020

Phenylketonuria is a disease caused by congenital defects in phenylalanine metabolism that leads to irreversible nerve cell damage. However, its detection in the early days of life can reduce its severity. Thus, many countries have started disease screening programs for neonates. The present study aimed to determine the worldwide prevalence of classic phenylketonuria using the data of neonatal screening studies.The PubMed, Web of Sciences, Sciences Direct, ProQuest, and Scopus databases were searched for related articles. Article quality was evaluated using the Joanna Briggs Institute Critical Appraisal Evaluation Checklist. A random effect was used to calculate the pooled prevalence, and a phenylketonuria prevalence per 100,000 neonates was reported. A total of 53 studies with 119,152,905 participants conducted in 1964-2017 were included in this systematic review. The highest prevalence (38.13) was reported in Turkey, while the lowest (0.3) in Thailand. A total of 46 studies were entered into the meta-analysis for pooled prevalence estimation. The overall worldwide prevalence of the disease is 6.002 per 100,000 neonates (95% confidence interval, 5.07-6.93). The meta-regression test showed high heterogeneity in the worldwide disease prevalence (I²=99%). Heterogeneity in the worldwide prevalence of phenylketonuria is high, possibly due to differences in factors affecting the disease, such as consanguineous marriages and genetic reserves in different countries, study performance, diagnostic tests, cutoff points, and sample size.

• 생태와환경
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• 제52권2호
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• pp.151-160
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• 2019

서식지 이질성은 복잡한 구조를 가진 서식지일수록 생물다양성이 증가된다는 개념으로 농업생태계에서도 적용이 가능하다. 특히 농업생태계에서 해충 조절과 같이 포식자로 기능하는 거미를 이용할 경우 농업생태계의 전반에 관한 이해의 폭을 넓힐 수 있다. 본 연구는 우리나라 농업생태계의 대표적인 재배 유형인 밭과 논에서 거미의 다양성이 공간 스케일에 따라 어떠한 특성을 나타내는지 확인하고자 수행하였다. 함정트랩을 설치하여 밭에서 24개 샘플을, 논에서 24개 샘플을 수집하였다. 공간 스케일에 따른 밭과 논의 종수는 누적 곡선과 추정 곡선을 통해 평가하였다. 전체 조사 지점들에서 종수는 밭에서 높게 나타났고 조사 지점별 평균 종수는 논에서 높게 나타났다. 이를 통해 작은 공간 스케일에서는 서식지 구조의 복잡성이, 큰 공간 스케일에서는 작물 종류의 다양성이 거미의 다양성에 영향을 미치는 것을 확인할 수 있었다.

• 암석학회지
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• 제24권2호
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• pp.77-90
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• 2015

피션트랙 검출에 의해 고체 및 액체상태 지질물질 내 우라늄을 정밀정량하는 최적기법을 제안하고 그 적용성을 검증하였다. 우라늄 정량은 중성자 조사에 의해 유도시킨 $^{235}U$의 핵분열 흔적을 트랙 디텍터에 기록하여 고배율 현미경 하에서 계수함으로써 이루어진다. 우라늄-친화력이 좋은 암석(예: 화강암, 석탄)을 분말 펠릿시료로 만들어 건식 검출하면, 그다지 높지 않은 우라늄함량(<5 ppm, 즉 ${\mu}g\;g^{-1}$)에서도 빈번하게 함유된 함-우라늄광물에 기인한 트랙 군집현상으로 인해 시료의 전체평균 함량 결정이 쉽지 않았으며, 트랙 균질부와 군집부를 별도로 검토해야 한다. 시료의 균질성이 유지된다면 백운모-Lexan 디텍터에 의한 중복 측정과 여러 차례 중성자 조사에 의한 반복 측정에서 높은 재현성이 확인되었다. 건고 액체시료 경우에 $10^1ppm$ 수준 및 그 이상의 우라늄함량에서 흔히 나타나는 불균질 현상을 극복하기 위해, 진공 석영튜브를 이용한 습식 검출법을 제안한다. 습식 검출에서 우라늄 균질성은 $10^0ppm$ 수준 이하에서 회복되며, 측정하한은 $10^2ppb$ (i.e. $ng\;g^{-1}$) 수준까지 무난한 것으로 입증되었다.

• 대한간호학회지
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• 제46권4호
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• pp.475-489
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• 2016

Purpose: This study was a systematic review and meta-analysis designed to investigate the effects of stimulation-oriented interventions for behavioral problems among people with dementia. Methods: Based on the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA), a literature search was conducted using seven electronic databases, gray literature, and other sources. Methodological quality was assessed using the Scottish Intercollegiate Guidelines Network (SIGN) for randomized controlled trials (RCTs). Data were analyzed using R with the 'meta' package and the Comprehensive Meta-Analysis (CMA 2.0) program. Results: Sixteen studies were included for meta-analysis to investigate the effect of stimulation-oriented interventions. The quality of individual studies was rated as '++' for eight studies and '+' for the rest. The effect sizes were analyzed according to three subgroups of interventions (light, music, and others); Hedges' g=0.04 (95% CI: -0.38~0.46), -0.23 (95% CI: -0.56~0.10), -0.34 (95% CI: -0.34~0.00), respectively. To explore the possible causes of heterogeneity ($I^2=62.8%$), meta-regression was conducted with covariates of sample size, number of sessions, and length of session (time). No moderating effects were found for sample size or number of sessions, but session time showed a significant effect (Z=1.96, 95% CI: 0.00~0.01). Finally, a funnel plot along with Egger's regression test was performed to check for publication bias, but no significant bias was detected. Conclusion: Based on these findings, stimulation-oriented interventions seem to have a small effect for behavioral problems among people with dementia. Further research is needed to identify optimum time of the interventions for behavioral problems among dementia pateints.

• 한국정보통신학회논문지
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• 제20권3호
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• pp.630-638
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• 2016

본 논문에서는 자연스러운 파노라마 영상 생성을 위해 SIFT와 SURF 방법보다 빠른 FAST(Features from Accelerated Segment Test)를 이용한 특징점 기반의 파노라마 영상 생성 기법을 제안한다. 다수의 영상을 이용해 자연스러운 파노라마 영상을 만들기 위해 실린더 투영을 수행 한 후 추출된 특징점들을 RANSAC(Random Sample Consensus)을 이용해 정합 시 오차율을 최소화한다. 서로 다른 방향에서 얻는 다수의 영상을 합성할 때 정합 경계 주변의 이질감을 보완하기 위해 블렌딩 기법을 사용함으로써 자연스러운 파노라마 영상을 생성한다. 제안하는 기법에서는 영상을 정합할 때 영상의 입력 순서와 방향에 관계없이 파노라마 영상을 만들 수 있다. 또한 기존의 방법보다 빠른 속도로 영상 정합이 가능하다. 다수의 영상으로 실험을 한 결과 왜곡이 보정되고 자연스러운 파노라마 영상을 생성할 수 있었다.

• 산업경영시스템학회지
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• 제32권2호
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• pp.29-37
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• 2009

National R&D programs play an important role in the development of a country in this age of the knowledge economy. Since many numbers of R&D programs compete for limited resources such as national R&D budget, the R&D program evaluation problem is a challenging decision-making problem faced by decision makers that deal with R&D management. In this sense, DEA(Data Envelopment Analysis) has been regarded as one of the most widely accepted methods to measure the relative efficiency of productivity of R&D programs. DEA is a methodology to measure and to evaluate the relative efficiency of a homogeneous set of decision-making units(DMUs) in a process which uses multiple inputs to produce multiple outputs. However, the sample of the R&D programs could consist of two or more naturally occurring subsets, thus exhibiting clear signs of heterogeneity such as different objectives. In such situations, the fairness of DEA is limited, for the nature of the relative efficiency of a DMU is likely to be influenced by its membership in a particular subset of the sample. In this study, we propose a methodology AI-DEA(attainment index DEA) allowing for reflecting decision maker's subjective judgement on difference among different subsets of R&D programs which have heterogeneous objectives. This methodology combines AHP and Delphi in order to decide the attainmnet index of each DMU for each outputs, and apply them to DEA model. We illustrate the proposed approach with a pilot evaluation of 13 programs involving 6 different subsets of Korean National R&D programs and compares the results of the original DEA model and AI-DEA model.

• Computers and Concrete
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• 제31권5호
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• pp.395-403
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• 2023

The paper investigates the effect of two parameters - sand content (SC) and grain migration during shearing - on the mechanical properties of gravel-sand mixtures. Consolidated undrained (CU) triaxial tests were carried out on eight series of mixtures containing gravel (1<d<16 mm) and sand (0.1<d<1 mm). The prepared mixtures have sand contents of 0, 10, 15, 20, 40, 54, 94 and 100%, and a relative density of 60%. The transition sand content (TSC) is experimentally defined and marks the transition from gravel-driven to sand-driven behavior. For SC<TSC, the dry density of the mixture increases with SC. This induces an increase in undrained peak strength and dilative trend. The slope and position of the critical state line (CSL) are also deeply dependent on SC. At SC=TSC, the mixtures exhibit the largest dry density and yield the highest undrained peak strength and the largest dilative trend. During shearing, large internal migration of grains was observed at the TSC, causing heterogeneity in the sample. Analysis of the CSL deduced from the final points of the triaxial tests shows that, at the TSC, failure appears to correspond to the behavior of the coarsest fraction of the soil. This fraction is located in the upper part of the sample, where the sand particles had been eliminated by suffusion. On the other hand, in the more stable materials, the CSL is consistent with the bulk grain size distribution of the soil.

• Geomechanics and Engineering
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• 제37권5호
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• pp.431-441
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• 2024

A newly developed line-style sand pluviator has been calibrated to prepare repeatable sand specimens of specific statuses of compactness and homogeneity for laboratory tests. Sand is falling via a bottom slot of a fixed hopper, and by moving the sample container under the slot, the container is evenly filled with sand. The pluviator is designed with high flexibility: The falling height of sand, the hopper's opening width and the relative moving speed between the hopper and the sample box can be easily adjusted. By changing these control factors, sand specimens of a wide range of densities can be prepared. A series of specimen preparation was performed using the coarse Merwede River sand. Performance of the pluviator was systematically evaluated by exploring the alteration of achievable density, as well as checking the homogeneity and fabric of the prepared samples by CT scanning. It was found that the density of prepared coarse sand samples has monotonic correlations with none of the three control factors. Furthermore, CT scanning results suggested that the prepared samples exhibited excellent homogeneity in the horizontal direction but periodical alteration of density in the vertical direction. Based on these calibration test results, a preliminary hypothesis is proposed to describe the general working principles of this type of pluviators a priori, illustrating the mechanisms dominating the non-monotonic correlations between control factors and the relative density as well as the vertically prevalent heterogeneity of specimens. Accordingly, practical recommendations are made in a unified framework in order to lessen the load of similar calibration work.