• Journal of Embryo Transfer
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• v.18 no.2
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• pp.115-124
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• 2003

The objective of this study was to compare the effect of four different estrus induction methods in anestrus cows on the estrus induction and pregnancy following artificial insemination (AI). Sixty-five cows (3∼4 years old) were selected and divided into four different estrus induction treatment groups. Group 1, 12 cows were treated by Ovsynch program combined with GnRH and PGF$_2$a. Group 2, 12 cows were treated by "Tow plus Two" program with GnRH and PGF$_2$a. Group 3, 20 cows were treated by "Tow plus Two" program following intravaginal progesterone implantation (CIDR). Twenty one cows in Group 4 were treated by "Tow plus Two" program following follicular rupture and intravaginal progesterone implantation. Cows were then observed estrus induction and inseminated artificially at 12 h and 24 h after standing estrus. The rates of estrus induction in Group 4 (18/21, 86%) was significantly (P<0.05) higher than those in groups 1, 2 and 3 (8/12, 67%; 9/12, 75%; 14/20, 70%). In the mean time of onset of estrus after final administration of GnRH in different hormone-treated cows, the cows in Group 3 (24.2$\pm$2.2) and Group 4 (23.4$\pm$2.0) were significantly (P<0.05) shorter than that in Group 1 (28.5$\pm$4.6) and Group 2 (26.4$\pm$3.3). The rates of pregnancy diagnosed on Day 28 were significantly different between treatment groups. Significantly (P<0.05) higher rate of pregnancy was observed in Group 4 (17/20, 85.0%) than those in Groups 1, 2 and 3 (7/11, 63.6%; 8/12, 66.7%; 15/20, 75.0%, respectetively). The rate of abortion diagnosed on 49 days of gestation was significantly (P<0/05) lower in Group 4 (1/17, 5.9%) than those in Groups 1, 2 and 3 (2/7, 28.7%; 2/8, 25% and 3/15, 20%, respectively). In conclusion, combined treatments with GnRH and PGF$_2$a following follicular rupture and progesterone implant in anestrus cows was considered to be most effective in estrus induction and maintenance of pregnancy. Further studies are needed to verify the functional mechanisms of residual follicles in anestrus ovaries on retarding the response of hormonal treatments.sponse of hormonal treatments.

• BMB Reports
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• v.48 no.6
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• pp.303-312
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• 2015

Receptor-interacting protein kinase-3 (RIP3, or RIPK3) is an essential protein in the "programmed", or "regulated" necrosis cell death pathway that is activated in response to death receptor ligands and other types of cellular stress. Programmed necrotic cell death is distinguished from its apoptotic counterpart in that it is not characterized by the activation of caspases; unlike apoptosis, programmed necrosis results in plasma membrane rupture, thus spilling the contents of the cell and triggering the activation of the immune system and inflammation. Here we discuss findings, including our own recent data, which show that RIP3 protein expression is absent in many cancer cell lines. The recent data suggests that the lack of RIP3 expression in a majority of these deficient cell lines is due to methylation-dependent silencing, which limits the responses of these cells to pro-necrotic stimuli. Importantly, RIP3 expression may be restored in many cancer cells through the use of hypomethylating agents, such as decitabine. The potential implications of loss of RIP3 expression in cancer are explored, along with possible consequences for chemotherapeutic response. [BMB Reports 2015; 48(6): 303-312]

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.36 no.11
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• pp.1094-1103
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• 2008

A fuel specific detonation wave in a pipe propagates with a predictable wave velocity. This internal detonation wave speed determines the level of flexural wave excitation of pipes and the possibility of resonant response leading to a large displacement. In this paper, we present particular solutions of displacements and the resonance conditions for internally loaded pipe structures. These analytical results are compared to numerical simulations obtained using a hydrocode(multi-material blast wave analysis tool). We expect to identify potential explosion hazards in the general power industries.

• Fisheries and Aquatic Sciences
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• v.19 no.7
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• pp.30.1-30.7
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• 2016

Due to decreased supplies of marine resources and byproducts, new processing technologies for the development of analogs for natural fishery products are becoming increasingly important in the fishing industry. In the present study, we investigated the optimal processing conditions for flying fish roe analogs based on alginate hydrogels. Optimized processing of these analogs was performed by response surface methodology. The optimal processing conditions for the flying fish roe analogs (based on sphericity) were at a sodium alginate concentration of 2.41 %, calcium chloride solution curing time of 40.65 min, calcium chloride concentration of 1.51 %, and a reactor stir speed of $254{\times}g$. When the experiment was performed under these optimized conditions, the size (mm), sphericity (%), and rupture strength (kPa) of the analogs were $2.2{\pm}0.12$, $98.2{\pm}0.2$, and $762{\pm}24.68$, respectively, indicating physical properties similar to their natural counterparts.

• Structural Engineering and Mechanics
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• v.34 no.6
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• pp.755-778
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• 2010

Near-fault ground motion with directivity or fling effects is significantly influenced by the rupture mechanism and substantially different from ordinary records. This class of ground motion has large amplitude and long period, exhibits unusual response spectra shapes, possesses high PGV/PGA and PGD/PGA ratios and is best characterized in the velocity and the displacement time-histories. Such ground motion is also characterized by its energy being contained in a single or very few pulses, thus capable of causing severe damage to the structures. This paper investigates the characteristics of near-fault pulse-like ground motions and their implications on the structural responses using new proposed measures, such as, the effective frequency range, the energy rate (in time and frequency domains) and the damage indices. The paper develops also simple mathematical expressions for modeling this class of ground motion and the associated structural responses, thus eliminating numerical integration of the equations of motion. An optimization technique is also developed by using energy concepts and damage indices for modeling this class of ground motion for inelastic structures at sites having limited earthquake data.

• Structural Engineering and Mechanics
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• v.28 no.4
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• pp.411-442
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• 2008

Ground motions in near source region of large crustal earthquakes are significantly affected by rupture directivity and tectonic fling. These effects are the strongest at longer periods and they can have a significant impact on Engineering Structures. In this paper, it is aimed to determine near-fault ground motion effects on the nonlinear response of dams including dam-reservoir-foundation interaction. Four different types of dam, which are gravity, arch, concrete faced rockfill and clay core rockfill dams, are selected to investigate the near-fault ground motion effects on dam responses. The behavior of reservoir is taken into account by using Lagrangian approach. Strong ground motion records of Duzce (1999), Northridge (1994) and Erzincan (1992) earthquakes are selected for the analyses. Displacements, maximum and minimum principal stresses are determined by using the finite element method. The displacements and principal stresses obtained from the four different dam types subjected to these nearfault strong-ground motions are compared with each other. It is seen from the results that near-fault ground motions have different impacts on the dam types.

• Earthquakes and Structures
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• v.20 no.1
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• pp.87-96
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• 2021

Ground motions recorded in near-fault sites, where the rupture propagates toward the site, are significantly different from those observed in far-fault regions. In this research, finite element modeling is used to investigate the effect of pile cap stiffness on the seismic response of soil-pile-structure systems under near-fault ground motions. The Von Wolffersdorff hypoplastic model with the intergranular strain concept is applied for modeling of granular soil (sand) and the behavior of structure is considered to be non-linear. Eight fault-normal near-field ground motion records, recorded on rock, are applied to the model. The numerical method developed is verified by comparing the results with an experimental test (shaking table test) for a soil-pile-structure system. The results, obtained from finite element modeling under near-fault ground motions, show that when the value of cap stiffness increases, the drift ratio of the structure decreases, whereas the pile relative displacement increases. Also, the residual deformations in the piles are due to the non-linear behavior of soil around the piles.

• Geomechanics and Engineering
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• v.34 no.6
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• pp.665-681
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• 2023

Liquefaction is one of the most devastating geotechnical phenomena that severely damage vital structures and lifelines. Before constructing structures on problematic ground, it is necessary to improve the site and solve the geotechnical problem. Among ground improvement methods dealing with liquefaction, gravel drain (GD) columns and deep soil mixing (DSM) columns are popular. In this study, the results of a series of seismic experiments in a 1g environment on a structure located over liquefiable ground with different thicknesses reinforced with GD and DSM techniques were presented. The dynamic response of the reinforced ground system was investigated based on the parameters of subsidence rate, excess pore water pressure ratio, and maximum acceleration. The time history of the input acceleration was applied harmonically with an acceleration range of 0.2g and at frequencies of 1, 2, and 3 Hz. The results show that the thickness of the liquefiable layer and the frequency of the input motion have a significant impact on the effectiveness of the improvement method and all responses. Among the two techniques used, DSM in thick liquefied layers was much more efficient than GD in controlling the subsidence and rupture of the soil under the foundation. Maximum settlement values, settlement rate, and foundation rotation in the thicker liquefied layer at the 1-Hz input frequency were higher than at other frequencies. At low thicknesses, the dynamic behavior of the GD was closer to that of the DSM.

• Geomechanics and Engineering
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• v.29 no.4
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• pp.451-461
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• 2022

The roadways surrounded by rock and coal will lose their stability or even collapse under rock burst. Rock burst mainly involves an evolution of dynamic loading which behaves quite differently from static or quasi-static loading. To compare the dynamic response of coal and rocks with different static strengths, three different rocks and bituminous coal were selected for testing at three different dynamic loadings. It's found that the dynamic compression strength of rocks and bituminous coal is much greater than the static compression strength. The dynamic compression strength and dynamic increase factor of the rocks both increase linearly with the increase of the strain rate, while those of the bituminous coal are irregular due to the characteristics of multi-fracture and heterogeneity. Moreover, the absorbed energy of the rocks and bituminous coal both increase linearly with an increase in the strain rate. And the ratio of absorbed energy to the total energy of bituminous coal is greater than that of rocks. With the increase of dynamic loading, the failure degree of the sample increases, with the increase of the static compressive strength, the damage degree also increases. The static compassion strength of the bituminous coal is lower than that of rocks, so the number of small-scale fragments was the largest after bituminous coal rupture.

• Corrosion Science and Technology
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• v.23 no.3
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• pp.246-254
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• 2024

Recently, coal-fired power plants are experiencing many problems that they have never experienced before due to an increase in flexible operation. In particular, a two-phase flow accelerated corrosion on water wall tubes in a boiler has not been detected overseas or domestically. There is no response plan to deal with such corrosion problem either. However, oxide film damage and tube material corrosion due to a two-phase flow accelerated corrosion are being discovered on water wall boiler tubes of domestic coal-fired power plants recently. If this situation is severe, it can cause enormous damage such as tube rupture. Therefore, in this paper, in order to prepare a response plan for a two-phase flow accelerated corrosion on water wall tubes in the future, differences between a two-phase flow accelerated corrosion and a single-phase flow accelerated corrosion were investigated and an example of discovery of a two-phase flow accelerated corrosion on water wall tubes was presented.