• Journal of Technology Innovation
• /
• v.13 no.1
• /
• pp.193-212
• /
• 2005

Leader-Member Exchange (LMX) model of leadership has suggested that members within the same work team are differentiated in terms of their level of the quality of leader member relationships. However, the differentiation in leader member relationships has not been examined for its possible team-level effects. In this study, the possible impact of this role differentiation on team members' affective reactions was explored. As hypothesized, teams whose members experienced higher level of LMX tended to have higher overall job satisfaction, organizational commitment, and team efficacy. Contrary to expectation, however, the team-level mean on LMX was not related with team-level variability on LMX. Based on these findings, several theoretical and practical Implications are discussed.

• Research in Plant Disease
• /
• v.18 no.3
• /
• pp.175-185
• /
• 2012

The problems caused by synthetic pesticides have led the need for effective biodegradable pesticides with greater selectivity. Botanical pesticides are generally recognized as safe in agriculture systems. Thus, they have been regarded as attractive alternatives to synthetic chemical pesticides for the pest management. Both lower efficacy and higher costs of production make botanicals more expensive to use than conventional pesticides. Moreover, only a small portion of plant-derived metabolites among a number of bioactive metabolites are in use because commercialization of botanicals is inhibited by several problems such as toxicity, or high production cost. However, with the growing acceptance of botanical pesticides as an efficient crop protection alternative resulting in increasing demand, plant-based pesticides will play a significant role in achieving sustainable agriculture in future.

• Korean Journal of Human Ecology
• /
• v.16 no.1
• /
• pp.17-26
• /
• 2007

The purpose of this study was to compare parenting stress between mothers who have young children with and without disabilities. The subjects of this study were 100 mothers who take care of disabled children and 123 mothers who take care of non-disabled children. The children's ages were from 3 to 6 years. The results of this study were as follows; First, the mothers who have disabled children have more parenting stress than those who have ordinary children. Second, the mothers who have developmentally disabled children had more parenting stress than mothers who had other disabled children. Children's and mothers' ages had an influence on the parenting stress of the ordinary mothers. The mothers who had children with and without disabilities got less parenting stress as the mothers received more higher parenting efficacy, parent role satisfaction, marital satisfaction and family support.

• The Journal of Korea Robotics Society
• /
• v.8 no.3
• /
• pp.206-216
• /
• 2013

We investigate the role of contact location information on the perception of local features during contour following in a virtual environment. An absolute identification experiment is conducted under force-alone and force-plus-contact-location conditions to investigate the effect of the contact location information. The results show that the participants identify the local features significantly better in terms of higher information transfer for the force-plus-contact-location condition, while no significant difference was found for measures of the efficacy of contour following between the two conditions. Further data analyses indicate that the improved identification of local features with contact location information is due to the improved identification of small surface features.

• The Korean Journal of Physiology and Pharmacology
• /
• v.18 no.6
• /
• pp.457-460
• /
• 2014

At central synapses, activity-dependent synaptic plasticity has a crucial role in information processing, storage, learning, and memory under both physiological and pathological conditions. One widely accepted model of learning mechanism and information processing in the brain is Hebbian Plasticity: long-term potentiation (LTP) and long-term depression (LTD). LTP and LTD are respectively activity-dependent enhancement and reduction in the efficacy of the synapses, which are rapid and synapse-specific processes. A number of recent studies have a strong focal point on the critical importance of another distinct form of synaptic plasticity, non-Hebbian plasticity. Non-Hebbian plasticity dynamically adjusts synaptic strength to maintain stability. This process may be very slow and occur cell-widely. By putting them all together, this mini review defines an important conceptual difference between Hebbian and non-Hebbian plasticity.

• Proceedings of the PSK Conference
• /
• 2002.10a
• /
• pp.250.2-251
• /
• 2002

DA-8159 is a new. highly selective. potent cyclic-GMP phosphodiesterase 5 inhibitor developed by Dong-A Pharmaceutical Company(Kyunggi, Korea) as an oral drug for the treatment of erectile dysfunction. NO- cGMP signal transduction pathway plays a key role for relaxation of corpus cavernosal smooth muscle. In this study. the efficacy of DA-8159 was evaluated by measuring the length of uncovered penile mucosa in spinal cord injury(SCI) rabbits. (omitted)

• Korean Journal of Biological Psychiatry
• /
• v.18 no.2
• /
• pp.80-89
• /
• 2011

Pavlovian fear conditioning has been extensively studied for the understanding of neurobiological basis of memory and emotion. Pavlovian fear conditioning is an associative memory which forms when conditioned stimulus (CS) is paired with unconditioned stimulus (US) once or repeatedly. This behavioral model is also important for the understanding of anxiety disorders such as posttraumatic stress disorder. Here we describe the neural circuitry involved in fear conditioning and the molecular mechanisms underlying fear memory formation. During consolidation some memories fade out but other memories become stable and concrete. Emotion plays an important role in determining which memories will survive. Memory becomes unstable and editable again immediately after retrieval. It opens the possibility for us of modulating the established fear memory. It provides us with very efficient tools to improve the efficacy of cognitive-behavior therapy and other exposure-based therapy treating anxiety disorders.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.11 no.sup1
• /
• pp.127-135
• /
• 2008

According to the hygiene hypothesis, westernized and urbanized life style leads to the increase of allergic disease. This hypothesis supports the use of probiotic therapy for the prevention or treatment of food allergy. The probiotics which contains potentially beneficial microorganism have been used for the treatment of some gastrointestinal disorders and atopic disease as dietary supplements. Many results of studies support the immunologic bases of probiotics therapy. The most important mechanism is that probiotics suppress Th2-skewed immunity as the stimulation of regulatory T cell. The difficulties of diagnosis of food allergy, variable symptoms, many kinds of microorganism, diet style and non-standardized study designs are attributed to the variety and controversy of the effectiveness of probiotics in food allergy with infant and children. More studies is needed to confirm the efficacy of probiotics in infant and children with food allergy.

• Asia pacific journal of information systems
• /
• v.14 no.2
• /
• pp.61-86
• /
• 2004

Despite their potential value, the mobile Internet services in the domestic market have not been widely accepted as industry experts have expected. To understand why, this study uses the TAM, Technology Acceptance Model, and explores the factors affecting the usage behavior of the end-users. Based on statistical analysis of survey data, we show that social influence and perceived ease of use affect perceived usefulness, and that self-efficacy and focus significantly influence perceived ease of use. Furthermore, perceived usefulness is shown to play a significant role in explaining actual usage of the mobile Internet services. However, contrary to the hypothesized relationships, service quality, focus, and innovativeness of users turn out to have little impact on the traditional endogenous TAM variables such as perceived usefulness, perceived ease of use, and actual usage behavior. Based on these results, we attempt to provide managerial implications for the domestic mobile Internet service providers and to suggest future research directions in this domain of research.

• Journal of Integrative Natural Science
• /
• v.9 no.4
• /
• pp.228-233
• /
• 2016

Cysteinyl leukotrienes are inflammatory mediators having important role in pathophysiological conditions such as asthma and allergic rhinitis. CysLT1 receptor mediates most of the disease regulatory actions of the CysLTs and it is been implicated in a number of inflammatory conditions including gastrointestinal and cardiovascular diseases. Hence in the present study, molecular docking of CysLT1 was performed with its potent and orally efficacious antagonist CP-199330 and CP-199331. The aim of this study was to compare the interaction of CP-199330 and CP-199331 with known drugs such as Zafirlukast, Pranlukast and Montelukast which had already showed clinical efficacy in the treatment of asthma. The residues such as TYR83, GLN274, LYS311 and SER313 were found to interact with both the antagonist and the known drugs. Also, we noticed the docking scores and interaction of the antagonists were comparable with the known drugs. Hence these antagonists could serve as better drugs for the treatment of allergy.