• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7459-7466
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• 2013

Background: Some 60 years after introduction of the Papanicolaou smear worldwide, cervical cancer remains a burden in developing countries where >85% of world new cases and deaths occur, suggesting a failure to establish comprehensive cervical-cancer control programs. Effective interventions are available to control cervical cancer but are not all affordable in low-income settings. Disease awareness saves lives by risk-reduction as witnessed in reducing mortality of HIV/AIDS and smoking-related cancers. Subjects and Methods: We initiated a community-based awareness program on cervical cancer in two low-income Muslim Uyghur townships in Kashi (Kashgar) Prefecture, Xinjiang, China in 2008. The education involved more than 5,000 women from two rural townships and awareness was then evaluated in 2010 and 2011, respectively, using a questionnaire with 10 basic knowledge questions on cervical cancer. Demographic information was also collected and included in an EpiData database. A 10-point scoring system was used to score the awareness. Results: The effectiveness and feasibility of the program were evaluated among 4,475 women aged 19-70 years, of whom >92% lived on/below US$1.00/day. Women without prior education showed a poor average awareness rate of 6.4% (164/2,559). A onetime education intervention, however, sharply raised the awareness rate by 4-fold to 25.5% (493/1,916). Importantly, low income and illiteracy were two reliable factors affecting awareness before or after education intervention. Conclusions: Education intervention can significantly raise the awareness of cervical cancer in low-income women. Economic development and compulsory education are two important solutions in raising general disease awareness. We propose that implementing community-based awareness programs against cervical cancer is realistic, locally affordable and sustainable in low-income countries, which may save many lives over time and, importantly, will facilitate the integration of comprehensive programs when feasible. In this context, adopting this strategy may provide one good example of how to achieve "good health at low cost".

• Korean Security Journal
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• no.27
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• pp.129-159
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• 2011

Physical security has always been an extremely important facet within the security arena. A comprehensive security plan consists of three components of physical security, personal security and information security. These elements are interrelated and may exist in varying degrees defending on the type of enterprise or facility being protected. The physical security component of a comprehensive security program is usually composed of policies and procedures, personal, barriers, equipment and records. Human beings kept restless struggle to preserve their and tribal lives. However, humans in prehistoric ages did not learn how to build strong house and how to fortify their residence, so they relied on their protection to the nature and use caves as protection and refuge in cold days. Through the history of man, human has been establishing various protection methods to protect himself and his tribe's life and assets. Physical security methods are set in the base of these security methods. Those caves that primitive men resided was rounded with rock wall except entrance, so safety was guaranteed especially by protection for tribes in all directions. The Great Wall of China that is considered as the longest building in the history was built over one hundred years from about B.C. 400 to prevent the invasion of northern tribes, but this wall enhanced its protection function to small invasions only, and Mongolian army captured the most part of China across this wall by about 1200 A.D. European lords in the Middle Ages built a moat by digging around of castle or reinforced around of the castle by making bascule bridge, and provided these protections to the resident and received agricultural products cultivated. Edwin Holmes of USA in 20 centuries started to provide innovative electric alarm service to the development of the security industry in USA. This is the first of today's electrical security system, and with developments, the security system that combined various electrical security system to the relevant facilities takes charging most parts of today's security market. Like above, humankind established various protection methods to keep life in the beginning and its development continues. Today, modern people installed CCTV to the most facilities all over the country to cope with various social pathological phenomenon and to protect life and assets, so daily life of people are protected and observed. Most of these physical security systems are installed to guarantee our safety but we pay all expenses for these also. Therefore, establishing effective physical security system is very important and urgent problem. On this study, it is suggested methods of establishing effective physical security system by using system integration on the principle of security design about effective security system's effective establishing method of physical security system that is increasing rapidly by needs of modern society.

• Journal of the Korean Institute of Landscape Architecture
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• v.43 no.3
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• pp.92-100
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• 2015

Unlike most other planning processes, brownfield planning generally requires a high level of technical and legal expertise due to potential site contamination. To successfully engage in inclusionary decision making, an adaptive collaboration strategy for brownfield planning is therefore critical. This study examines how a communicative planning approach can be used to overcome the challenge of enabling experts from different fields to work alongside lay people from the local community to achieve a properly balanced collaboration in brownfield planning. After identifying appropriate indicators for collaboration through a literature review of established communicative planning theory, these indicators are applied to the brownfield planning process, highlighting critical points of collaboration such as site prioritization, assessment, remediation, and redevelopment throughout. The results suggest the critical need for an adaptive model focusing on three aspects: 1. Facilitation of a balanced dialogue between the experts with social, cultural, and design-based knowledge and the ones with scientific and engineering-based knowledge, 2. Preparation of an appropriate tool for risk communication with the lay people, 3. Development of decision support system for the integration of expert-oriented technical data and public opinion-oriented subjective data.

• Journal of the Economic Geographical Society of Korea
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• v.19 no.4
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• pp.597-615
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• 2016

Since 1997 the United Kingdom has pursued creative industry and creative city development in accordance with the New Labor Party policy, strengthening its cluster policy by assigning creative city policies to traditional manufacturing-oriented regions. Tech City in London, one of the most successful examples of digital clusters, is an area in which diverse ecosystems for venture business integration have been established, as the once barren space began to spontaneously develop. For this region, systematic linkages including universities, private companies, start-ups, and accelerators have been added, along with the UK government's active support system. As a result of this opportunity, the scale of the UK start-up ecosystem has significantly grown, the number of local companies has surged, and brand effect has greatly improved. Tech City is an example of a well-balanced combination of public effort and private governance, based on the region's historical background and its potential for growth. It is an effective coordination of public policy and private active investment, services, research, and education. The market platform for institutional technology and commercialization, and aggressive investment shares in the risk, have lead to its growth as a start-up and an innovative city. Britain's efforts to expand the nationwide cluster for the future-oriented digital economy is most noteworthy.

• BMB Reports
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• v.51 no.11
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• pp.584-589
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• 2018

Secondary prevention via earlier detection would afford the greatest chance for a cure in premalignant lesions. We investigated the exomic profiles of non-malignant and malignant changes in head and neck squamous cell carcinoma (HNSCC) and the genomic blueprint of human papillomavirus (HPV)-driven carcinogenesis in oropharyngeal squamous cell carcinoma (OPSCC). Whole-exome (WES) and whole-genome (WGS) sequencing were performed on peripheral blood and adjacent non-tumor and tumor specimens obtained from eight Korean HNSCC patients from 2013 to 2015. Next-generation sequencing yielded an average coverage of $94.3{\times}$ for WES and $35.3{\times}$ for WGS. In comparative genomic analysis of non-tumor and tumor tissue pairs, we were unable to identify common cancer-associated early mutations and copy number alterations (CNA) except in one pair. Interestingly, in this case, we observed that non-tumor tonsillar crypts adjacent to HPV-positive OPSCC appeared normal under a microscope; however, this tissue also showed weak p16 expression. WGS revealed the infection and integration of high-risk type HPV16 in this tissue as well as in the matched tumor. Furthermore, WES identified shared and tumor-specific genomic alterations for this pair. Clonal analysis enabled us to infer the process by which this transitional crypt epithelium (TrCE) evolved into a tumor; this evolution was accompanied by the subsequent accumulation of genomic alterations, including an ERBB3 mutation and large-scale CNAs, such as 3q27-qter amplification and 9p deletion. We suggest that HPV16-driven OPSCC carcinogenesis is a stepwise evolutionary process that is consistent with a multistep carcinogenesis model. Our results highlight the carcinogenic changes driven by HPV16 infection and provide a basis for the secondary prevention of OPSCC.

• Journal of Korea Multimedia Society
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• v.17 no.2
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• pp.170-179
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• 2014

Recently the U-Healthcare system has been rapidly advanced to manage emergence rescue for seniors. We can access emergency rescue systems with high quality services anytime, anywhere under ubiquitous healthcare systems. The more the various systems develop, the more software security systems become important. Therefore, the safety-critical system has been widely spread to the world by advancement of the information and communication technologies. There are a lot kind of fault analysis methods to evaluate software security systems. However due to characteristics of software that is not applied by human error, it can be prevented the enormous damages and losses from improving the safety of safety-critical system. So this paper proposes an integration method of FTA and Forward and Backward FMECA. This method has each strength of FTA and FMECA which is visual and numeric in normalization. First, by use of FTA, we can redraw FTA with Forward FMECA and Backward FMECA in consideration of occurrence, severity, detection, correctness, robustness, and security. Also according to value of NRVP at each event, we can modify FTA diagrams as shown critical paths given by severity and occurrence. Also, we propose the improved emergency rescue service platform of ubiquitous healthcare systems through identifying priorities of the criticality according to normalized risk priority values (NRPV).

• The Journal of the Korea Contents Association
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• v.18 no.4
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• pp.416-427
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• 2018

As the loan size of real estate PF is huge, its market ripple effect gets bigger when overdue occurs. Accordingly, the management of the delinquency rate and macroeconomic analysis are required. As the preceding research mainly proceeded with microeconomic analysis through the real estate PF data of individual banks to evaluate importance of list or analyzed core factors for delinquency, it lacked research on comprehensive real estate PF size. In order to overcome the limitations of such data, this research studied real estate PF delinquency rate of the entire market and effect relationship by the size. The research utilized the size of real estate PF loans, money supply, interest rate, consumer price index(CPI), and GDP data. Also, it applied the first model of VECM as linear relationship between at least two or more variables, following the result of co-integration test. As a result of Granger-causality test, the real estate PF loans delinquency rate is influenced by their loan size, and as a result of impulse response analysis, the interest rate is shown to be affecting delinquency rate the most. Interest rate could risesomeday and aggravate the delinquency rate of real estate PF. Also, risk exposure could be serious as the loan size increases.Therefore, the management of real estate PF delinquency rate requires continuous monitoring, tracking and observing issued loans from a macro point of view. The plans to prevent delinquency will be necessary.

• Journal of the Korean association of regional geographers
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• v.10 no.2
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• pp.252-266
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• 2004

This study analyzes the influence of the construction of a high-speed railroad on territorial organization in France. After development of a new transportation network, the French territorial organization has been largely modified. Many economic urban areas are modified by their position in the territorial hierarchy according to their condition of connection with the TGV network. At first, spatial convergence is the most important effect of the TGV network construction. Second, the development of a transportation network concentrated in the Paris area has influence as an intensified factor on metropolitan areas and as a weakening factor on middle- and small-sized cities. Thus, this system has risk in increasing territorial imbalance in France. Third, to implant an economic activity zone around new TGV stations, a new town or a new economic center starts to develop. This is going to grow into a second core outside of the old city center so that regional spatial organization is transformed from a mono-polarized(mono-centric) organization to a multi-polarized(polycentric) one. Lastly, the integration of the EU railroad system enhances the concentration of economic activity in European metropolitan areas as each metropolitan area tries to develop more competitive space for its rising position in the global urban hierarchical system.

• Journal of the Korean Society of Marine Environment & Safety
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• v.26 no.2
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• pp.129-138
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• 2020

This study recognizes problems in the current system of providing navigation safety information (NSI), which is centered on merchant ships, to prevent maritime accidents of fishing boats and small vessels in coastal areas. The system proposed in this study is an effective method of providing NSI to support the safe navigation of small vessels such as fishing boats. First, the status and characteristics of recent maritime accidents were examined, and NSI service targets were identified. Second, the limitations of the current NSI system were determined, and measures were proposed to establish an NSI Integrated Platform (NSIP) that ensures the integration, accessibility, and usability of NSI for a substantial portion of the public. Third, to utilize the NSIP, various NSIs are applied as additional information for the electronic chart system used in the e-navigation ship terminals being developed in connection with the Korean e-navigation project. Functions that set the audiovisual alarm function to automatically operate when a ship enters a navigation risk zone is proposed. These functions are technically achieved by reviewing expert opinions of related organizations and professional producers. The results of this study suggest that NSI can be applied to small vessels such as fishing boats, through the Korean e-Navigation project, to prevent maritime accidents caused by the human error of navigators.

• KIPS Transactions on Software and Data Engineering
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• v.6 no.9
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• pp.419-428
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• 2017

In an embedded system, modules exchange data by interacting among themselves. Exchanging erroneous resource data among modules may lead to execution errors. The interacting resources produce dependencies between the two modules where any change of the resources by one module affects the functionality of another module. Several investigations of the embedded systems show that interaction faults between the modules are one of the major cause of critical software failure. Therefore, interaction testing is an essential phase for reducing the interaction faults and minimizing the risk. The direct and indirect interactions between the modules generate interaction faults. The direct interaction is the explicit call relation between the modules, and the indirect interaction is the remaining relation that is made underneath the interface that possesses data dependence relationship with resources. In this paper, we investigate the errors that are based on the indirect interaction between modules and introduce a new test criterion for identifying the errors that are undetectable by existing approaches at the integration level. We propose a novel approach for generating the interaction model using the indirect interaction pattern and design test criteria that are based on different interaction errors to generate test cases. Finally, we use the fault injection technique to evaluate the feasibility and effectiveness of our approach.