• Journal of Pharmacopuncture
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• v.16 no.3
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• pp.23-29
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• 2013

Objectives: Dyslipidemia in diabetes mellitus is a significant risk factor for the development of cardiovascular complications. The aim of this study was to evaluate the effect of the ethyl-acetate fraction of an ethanolic extract from Streospermum suaveolens on lipid metabolism in streptozotocin (STZ)-induced diabetic rats. Methods: Diabetes was induced by intraperitonial injection of STZ (50 mg/kg). Diabetic rats were treated with an ethyl-acetate fraction orally at doses of 200 and 400 mg/kg daily for 14 days. On the $15^{th}$ day, serum lipid profiles, such as total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL), and high-density lipoprotein (HDL), were estimated in experimental rats. The atherogenic (AI) and the coronary risk (CRI) indices were also evaluated. Results: The ethyl-acetate fraction at doses of 200 and 400 mg/kg significantly (P < 0.001) and dose-dependently reduced serum cholesterol, triglycerides and LDL, but increased HDL towards near normal levels as compared to diabetic control rats. The fraction also significantly (P < 0.001) lowered the atherogenic index (AI) and coronary risk index (CAI) in a dose-dependent manner. Conclusion: The present study demonstrated that the ethyl-acetate fraction of Stereospermum suaveolens exhibits a potent antihyperlipidemic activity in hyperglycemic rats and suggests that the plant may have therapeutic value in treating the diabetic complication of hyperlipidemia.

• Journal of Korea Water Resources Association
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• v.56 no.8
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• pp.521-528
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• 2023

An approach for producing a rip current risk index using the rip current likelihood distribution obtained through the FUNWAVE simulations was applied to a rip current forecast system. The approach originally developed for an observation-based real-time rip current warning system was utilized with wave forecast data instead of observations for the rip current forecast system. The availability of the present approach was checked by comparing the observation-based rip current risk index and the wave forecast-based rip current risk index of the Haeundae Beach in 2021.

• Korean Journal of Child Studies
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• v.25 no.5
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• pp.147-161
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• 2004

This study was designed to explore developmental evaluation in healthy full-term, at risk preterm and full-term infants. Specifically the purposes of the study were to investigate Psychomotor Developmental Index(PDI) and Mental Developmental Index(MDI) based on Bayley Scales of Infant Development(1993). The subjects were 72 infants, 24 each for healthy full-term infants, 24 each for at risk preterm infants and 24 each for at risk full-term infants such as having neonatal asphyxia, hypoxic ischemic brain damage, respiratory distress syndrome. The data were analyzed through Kruskal-Wallis test and correlations to examine healthy full-term, at risk pre-term and at risk full-term infants. Results showed that there were significant differences among healthy full-term, at risk pre-term and at risk full-term infants in PDI and MDI. On the correlation with PDI and MDI, infants showed significant correlations. Early interventions for developmental improvement are required for functional outcome in these infants.

• Korean Journal of Construction Engineering and Management
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• v.8 no.4
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• pp.99-109
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• 2007

Risk elements of highway safety facilities are affected by complex environments. Thus, risk-based approach for traffic safety facilities is needed. For this, in this study, qualitative and quantitative risk assessment methodology and procedure for highway safety facilities is proposed, which can be used as risk-based approach incorporating VE process. Also, for the quantitative risk assessment, event tree using EPDO(Equivalent Property Damage Only) with respect to frequency and magnitude of risk events is introduced. As a result, risk index of alternative 1(140cm) and 2(127(cm) which can be used as performance factor in VE approach are estimated.

• Asia pacific journal of information systems
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• v.8 no.2
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• pp.37-51
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• 1998

This study attempts to draw a blueprint of risk analysis for Information Systems (IS). We introduce two main variables for measuring IS risk - business-impact intensity and IS-vulnerability index - through the investigation of information characteristics, business processes and human-related factors. IS-vulnerability index consists of two factors such as degree of openness and degree of preparedness to the threats. Based on these factors, we built two integrative frameworks for risk analysis and management: One is a conceptual framework to enhance the understandability of IS risk itself; the other is an integrative framework to improve the managerial insight of overall IS risk. We then conducted a field study to empirically validate the proposed framework using a structural equations modeling method. We found that IS maturity and business-impact intensity were positively correlated to degree of openness to the threats, while IS maturity was negatively correlated to degree of preparedness to the threats.

• International conference on construction engineering and project management
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• 2009.05a
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• pp.1000-1014
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• 2009

Research sponsored by the Korean Government investigated the establishment of a risk management process by Korean contractors involved with plant projects in the Middle East. This research effort builds upon the work completed by the Construction Industry Institute (CII), called the International Project Risk Assessment (IPRA) tool and method, and also explored how CII's Project Definition Rating Index (PDRI) could be incorporated to improve project planning by addressing risks and scope development issues. Specific findings and recommendations were developed including the creation of the Contractor Critical Areas of Concern (CCAC) risk screening tool for Korean contractors pursuing Middle East oil and gas projects.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.4B
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• pp.203-211
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• 2012

Once drought occurs, it results in the extensive affected area and considerable socio-economic damages. Thus, it is necessary to assess drought risk and to prepare its counterplans. In this study, using various observation data on meteorological and socio-economical factors, drought risk was evaluated in South Korea. To quantify drought risk, Drought Hazard Index (DHI) was calculated based on the occurrence probability of drought, and Drought Vulnerability Index (DVI) was computed to reflect socio-economic consequences of drought. Drought Risk Index (DRI) was finally suggested by combining DHI and DVI. These indices were used to assess drought risk for different administrative districts of South Korea. The overall results show that the highest drought risk area was Jeolla Province where agricultural practice is concentrated. The drought risk map proposed in this study reflects regional characteristics, thus it could be utilized as a basic data for the establishment of drought preventive measures.

• Journal of radiological science and technology
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• v.46 no.4
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• pp.303-313
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• 2023

This study aimed to investigate the relevance of cardiovascular disease risk factors AI and AIP, divided into three groups, among 300 individuals who underwent health checkups at the hospital. Various variables such as Age, Sex, BMI, WC, TC, TG, HDL-C, LDL-C, FBS, HbA1C, SBP, DBP, HR, AI (TC/HDL-C), and AIP (log(TG/HDL-C)) were analyzed using statistical methods including frequency analysis, cross-tabulation, one-way ANOVA, Pearson's correlation analysis, and multiple linear regression analysis. The cross-analysis based on cardiovascular disease risk criteria revealed that men and individuals in their 50s had higher cardiovascular disease risk based on AI and AIP. Significant differences were observed in TG, TC, HDL-C, LDL-C, SBP, DBP, AI (TC/HDL-C), and AIP (log(TG/HDL-C)) according to AI criteria. For the AIP criteria, TG, TC, HDL-C, FBS, HbA1C, HR, AI (TC/HDL-C), and AIP (log(TG/HDL-C)) were identified as cardiovascular disease risk factors. FBS and HbA1c showed the highest positive correlation In the correlation analysis, followed by TC and LDL-C. The lowest positive correlation was observed between LDL-C and DBP. In terms of negative correlation, HDL-C and AI had the highest negative correlation, while LDL-C and TG showed the lowest negative correlation. Multiple regression analysis indicated that the AI and AIP risk criteria had explanatory powers of 73.6% and 72.5%, respectively. HDL-C had the greatest negative effect on the AI risk criterion, while TG had the most significant influence on the AIP risk criterion. In conclusion, while other serological variables are important, managing HDL-C and TG levels may help reduce the risk of cardiovascular disease.

• Tuberculosis and Respiratory Diseases
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• v.87 no.3
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• pp.357-367
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• 2024

Background: Obstructive sleep apnea (OSA) is a prevalent sleep disorder associated with various health issues. Although some studies have suggested an association between reduced lung function and OSA, this association remains unclear. Our study aimed to explore this relationship using data from a nationally representative population-based survey. Methods: We performed an analysis of data from the 2019 Korea National Health and Nutrition Examination Survey. Our study encompassed 3,675 participants aged 40 years and older. Risk of OSA was assessed using the STOP-Bang (Snoring, Tiredness during daytime, Observed apnea, and high blood Pressure-Body mass index, Age, Neck circumference, Gender) questionnaire and lung function tests were performed using a portable spirometer. Logistic regression analysis was applied to identify the risk factors associated with a high-risk of OSA, defined as a STOP-Bang score of ≥3. Results: Of 3,675 participants, 600 (16.3%) were classified into high-risk OSA group. Participants in the high-risk OSA group were older, had a higher body mass index, and a higher proportion of males and ever-smokers. They also reported lower lung function and quality of life index in various domains along with increased respiratory symptoms. Univariate logistic regression analysis indicated a significant association between impaired lung function and a high-risk of OSA. However, in the multivariable analysis, only chronic cough (odds ratio [OR], 2.413; 95% confidence interval [CI], 1.383 to 4.213) and sputum production (OR, 1.868; 95% CI, 1.166 to 2.992) remained significantly associated with a high OSA risk. Conclusion: Our study suggested that, rather than baseline lung function, chronic cough, and sputum production are more significantly associated with OSA risk.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.43 no.3
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• pp.309-319
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• 2023

Recently, the frequency and intensity of meteorological disasters have increased due to climate change. In South Korea, there are regional differences in vulnerability and response capability to cope with climate change because of regional climate characteristics. In particular, drought results from various factors and is linked to extensive meteorological, hydrological, and agricultural impacts. Therefore, in order to effectively cope with drought, it is necessary to use a composite drought index that can take into account various factors, and to evaluate future droughts comprehensively considering climate change. This study evaluated hydrologic risk(${\bar{R}}$) of future drought in the Nakdong River basin based on the Dynamic Naive Bayesian Classification (DNBC)-based composite drought index, which was calculated by applying Standardized Precipitation Index (SPI), Streamflow Drought Index (SDI), Evaporate Stress Index (ESI) and Water Supply Capacity Index (WSCI) to the DNBC. The indices used in the DNBC were calculated using observation data and climate scenario data. A bivariate frequency analysis was performed for the severity and duration of the composite drought. Then using the estimated bivariate return periods, hydrologic risks of drought were calculated for observation and future periods. The overall results indicated that there were the highest risks during the future period (2021-2040) (${\bar{R}}$=0.572), and Miryang River (#2021) had the highest risk (${\bar{R}}$=0.940) on average. The hydrologic risk of the Nakdong River basin will increase highly in the near future (2021-2040). During the far future (2041-2099), the hydrologic risk decreased in the northern basins, and increased in the southern basins.