• 제목/요약/키워드: risk and meta-analysis

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수술 후 폐 합병증 예방을 위한 심호흡 운동의 효과에 대한 체계적 고찰 (Effectiveness of Deep Breathing Exercise for Postoperative Pulmonary Complications Prevention: A Systematic Review)

  • 이월숙;양유리;오의금
    • 기본간호학회지
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    • 제21권4호
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    • pp.423-432
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    • 2014
  • Purpose: This study was done to evaluate effectiveness of deep breathing exercise as a postoperative intervention to prevent pulmonary complications. Methods: A search of databases from 1990 to 2012 was done including MEDLINE, EMBASE, CINAHL, Cochrane Library and eight Korean databases. Ten studies met eligibility criteria. Researchers trained in systematic review, independently assessed the methodological quality of selected studies using the Cochrane's risk of bias tool. Data were analyzed using RevMan 5.2 program. Results: Among ten RCTs in four studies, deep breathing exercise was compared with an instrument using interventions such as incentive spirometry, in the other four studies deep breathing exercise was compared with non-intervention, and in last two studies bundles of interventions including coughing and early ambulation were assessed. A significant difference was found between deep breathing exercise group and non-intervention group. The odds ratio (OR) of occurrence of pulmonary complications for deep breathing exercise versus non-intervention was 0.30. However, there was no significant difference between deep breathing exercise group and incentive spirometry group (OR=1.22). Conclusion: Deep breathing exercise is vital to improving cost-effectiveness and efficiency of patient care in preventing postoperative pulmonary complications. For evidence-based nursing, standardized guidelines for deep breathing in postoperative care should be further studied.

원발성 월경통의 추나 치료에 대한 체계적 문헌 고찰 (Chuna Manual Therapy for Primary Dysmenorrhea: A Systematic Review)

  • 서하라;이옥진;이재은;김명규
    • 한방재활의학과학회지
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    • 제27권3호
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    • pp.81-93
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    • 2017
  • Objectives The purpose of this study is to evaluate the effectiveness of Chuna therapy for primary dysmenorrhea. Methods Researchers searched on 7 electronic databases (Pubmed, National Digital Science Library, China National Knowledge Infrastructure, Wangfang med online, Korean Studies Information Service System, Research Information Sharing Service and Oriental medicine Advanced Searching Integrated System). The search included Korean, English, Chinese reports and there was no limit on the search period. All of randomized controlled clinical trials (RCTs) that used Chuna manual therapy for primary dysmenorrhea were selected. Results 27 RCTs met required condition. Meta-analysis showed positive results for Chuna manual therapy for primary dysmenorrhea in terms of therapeutic effects and reduction of symptom scores compared to west medicine, herbal medicine, acupucture and other treatments. Conclusions Above results showed that performing chuna is effective in treating dysmenorrhea. However, in some studies, there was no statistic significance between the experimental group and the control group. Also, according to Cochrane Risk of Bias (RoB) evaluation method, quality of the studies were not high enough. Since most of the materials were in Chinese, more high-quality clinical trials about Chuna therapy for primary dysmenorrhea are needed in Korea.

중국 및 한국 Database에서의 위식도 역류질환에 대한 반하사심탕의 효과에 대한 최근 10년간의 연구경향 (A Study Trend for the Effects of Banxia-xiexin-tang Decoction (Banhasasim-tang) on Gastroesophageal Reflux Disease (GERD) in Chinese and Korean Databases over the Last Ten Years)

  • 정유진;김윤정;홍상훈
    • 대한한방내과학회지
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    • 제41권3호
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    • pp.362-413
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    • 2020
  • Objectives: The purpose of this research is to examine the recent clinical research trends on the efficiency of traditional herb medicine (THM) on gastroesophageal reflux disease (GERD), and to provide clinical evidence of herbal medicine, Banhasasin-tang or Banxiexin decoction by using a systemic review and meta-analysis of randomized trials (RCTs). Methods: In this study, randomized controlled trials (RCTs) were included that verified effects of traditional herbal medicine (THM), including a Banxia-xiexin-tang decoction, as a treatment for GERD. A study of the literature in Chinese and Korean databases was performed for papers published from January 1, 2010, to January 1, 2020. The selected literature was assessed by Cochrane's risk of bias (RoB). Results: A total of 90 RCTs met the inclusion criteria. Except for four RCT studies, all studies identified the effect of a Banxia-xiexin-tang decoction in the treatment of GERD. The effectiveness of treatment was significantly higher in the intervention group than in the control group, as shown through various evaluation indicators, including the reflux disease diagnostic questionnaire (RDQ). Adverse effects were reported in 22 articles (24.44%). Conclusions: Treatment with Banhasasin-tang, or a Banxia-xiexin-tang decoction, was found to be effective in treating GERD. However, due to the low quality of available studies, the significance of this conclusion is somewhat limited. This study could serve as a foundation for further clinical studies on the development of diagnosis and treatment methods for GERD based on Korean medicine.

한약이 류마티스 관절염 환자의 골다공증에 미치는 영향: 체계적 문헌 고찰 및 메타분석을 위한 프로토콜 (Effects of Herbal Medicines on Osteoporosis in Rheumatoid Arthritis: Study Protocol for a Systematic Review and Meta-Analysis)

  • 권도영;구지향;이은정
    • 한방재활의학과학회지
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    • 제32권3호
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    • pp.77-84
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    • 2022
  • Objectives This study is designed to identify the effectiveness of herbal medicine for osteoporosis in rheumatoid arthritis. Methods We will investigate 10 databases, 4 Korean databases (KoreaMed, KMBASE, Koreanstudies Information Service System [KISS], ScienceOn) and 6 of abroad (PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure [CNKI], WanFang, Citation Information by NII [CiNii]) without publication date, language limitation for clinical study of herbal medicine for osteoporosis in rheumatoid arthritis. Type, dose, duration, frequency of herb medicine will be analyzed. Results Randomized controlled trials about herbal medicine or herb extract for osteoporosis in rheumatoid arthritis should be included in the study. Cochrane's risk of bias tools will be used to assess quality of the study. Mean differences or standardized mean differences of 95% confidence intervals will calculated and data synthesis will be conducted using Review Manager (RevMan, ver.5.3; The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen, Denmark). Conclusions It is expected to provide basic data for the active use of herb medicine by systematically synthesizing and analyzing the actual situation, effectiveness, and safety of herb medicine for osteoporosis in rheumatoid arthritis.

척추마취 후 두통완화를 위한 침상안정 효과에 대한 융복합적 문헌고찰 (Review for Effectiveness of Bedrest on Post-Dural Puncture Headache)

  • 송영신;김지혜;김경옥
    • 디지털융복합연구
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    • 제15권3호
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    • pp.229-236
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    • 2017
  • 척추마취 후 두통완화를 위한 침상안정에 대한 연구에 대한 체계적 문헌고찰을 통해 이들 연구에서 사용된 연구설계, 대상자 및 주요 중재방법과 그 효과에 대해 분석하였다. 연구추출을 위해 1980년부터 2016년까지 총 4234의 문헌중 15편의 연구논문을 분석하였다. 그 결과 5239명의 척추마취를 시행한 대상자가 연구에 참여하였으며, 실험연구가 10편, 비실험연구 5편이 포함되었다. 실험연구 대부분 24시간 침상안정군을 대조군으로 선정하여 다양한 시간의 침상안정에 따른 두통 발현율을 비교하였는데 2편의 논문을 제외한 연구에서 조기이상군의 두통발현율이 낮았다. 개별연구의 연구 질 평가결과를 감안하여 척추마취 후 두통을 완화시키기 위한 적절한 침상안정시간을 산정하기 위해 다양한 연구시도와 기존연구를 이용한 메타분석연구가 필요한 것으로 사료된다.

슬관절 전치환술 환자에 적용한 추나치료: 체계적 문헌고찰 및 메타분석 (Chuna Manual Therapy for Patients after Total Knee Arthroplasty: A Systematic Review and Meta-Analysis)

  • 이은별;이윤진;김현지;안희덕;양두화
    • 척추신경추나의학회지
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    • 제16권1호
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    • pp.13-23
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    • 2021
  • Objectives To assess the effectiveness of chuna manual therapy for patients with total knee arthroplasty. Methods We searched 9 electronic databases(KISS, NDSL, RISS, OASIS, KMBASE, Cochrane Library, PubMed, CNKI, Wangfang data) using the keywords 'total knee arthroplasty OR total knee replacement' and 'tuina OR chuna' to identify RCTs that investigated the effectiveness of Chuna manual therapy after total knee arthroplasty. Results 23 RCTs were selected based on inclusion criteria. The systematic review showed positive effect of using chuna manual therapy after total knee arthroplasty. Conclusions 23 studies reported that chuna manual therapy had significant effects on total knee arthroplasty. However, many studies were exposed to probable high risk of bias. Also, all of the studies were published in one overseas country. Therefore, further research is required using well-designed RCTs to support the effectiveness of chuna manual therapy.

태변흡인증후군에서 폐표면활성제 사용이 호흡기지표에 미치는 영향에 대한 체계적 문헌고찰과 메타분석 (The Effect on Pulmonary Indices of Surfactant Therapy for Meconium Aspiration Syndrome: Systematic Review and Meta-analysis)

  • 최현진;한서경;이순민;김한석;배종우
    • Neonatal Medicine
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    • 제18권2호
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    • pp.189-196
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    • 2011
  • 목적: 최근 폐표면활성제는 태변흡인증후군 환자에서 호흡곤란을 호전시키기 위한 치료 중 하나로 사용되고 있다. 본 연구에서는 태변흡인증후군에서 폐표면활성제가 치료결과로서 호흡기지표에 미치는 영향을 살펴보았다. 방법: MEDLINE, EMBASE, CENTRAL 등의 주요 데이터베이스 및 초록 등을 검색하여 2011년 6월까지 보고된 관련 무작위 배정연구를 선별하였다. OI 또는 a/A $PO_2$와 같은 호흡기 지표를 포함한 자료를 추출하여 폐표면활성제 보충요법과 폐표면활성제 세정요법 각각에 대해 메타분석을 수행하였다. 비뚤림 위험 및 임상적, 통계적 이질성을 평가하였다. 결과: 두 건의 폐표면활성제 보충요법 연구와 두 건의 폐표면 활성제 세정요법 연구가 분석에 포함되었다. 폐표면활성제 보충요법의 경우 OI에서는 두 연구 결과 사이의 이질성이 큰 반면, a/A $PO_2$에서는 보충요법 후 시간이 경과할 수록 군 간의 차이가 유의하게 나타났다(12시간째 WMD 0.08, 95% CI 0.04, 0.12; 24시간째 WMD 0.17, 95% CI 0.06, 0.28). 폐표면활성제 세정요법의 경우 통합하여 분석하였을 때 치료군이 대조군에 비해 임상 경과가 좋은 경향을 보였으나 통계적인 유의성은 확보하지는 못하였다. 결론: 태변흡인증후군에서 폐표면활성제 사용은 임상경과를 호전시키는 것으로 보인다. 기존의 연구수가 제한되어 있고 대상환자의 중증도 및 폐표면활성제 투여방법 또한 서로 다르므로 추가적인 연구를 통한 보충적인 근거가 도움이 될 것이다.

Metaverse 시대의 신기술 사용 의도에 영향을 미치는 요인: B2C 맥락과 B2B 맥락의 차이를 중심으로 (Factors Influencing Acceptance and Use of New Technologies in the Metaverse Era : Focusing on the Difference between B2C Context and B2B Context)

  • 정병규
    • 벤처혁신연구
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    • 제4권3호
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    • pp.125-139
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    • 2021
  • 4차산업혁명이 진전되면서 새로운 기술이나 서비스들이 탄생, 성장, 성숙해 가고 있다. 이제는 모바일 시대를 넘어 새로운 패러다임으로 metaverse에 대한 논의가 진행이다. 이에 본 연구에서는 메타버스 시대를 대비하여 새로운 기술을 소비자들이 사용하고자 할 때 어떠한 요인들이 중요하게 영향을 미치는지에 대해 분석하고자 했다. 특히 소비자들이 해당 기술을 사용하는 맥락이 B2C인지 B2B인지에 따라 어떻게 달라지는지에 초점을 두고 연구를 진행하였다. 이를 위해 연구 대상을 메타버스 시대와 연계해서 B2C 맥락에서는 증강 현실(AR)을 선정하였고, B2B 맥락에서는 스마트 팩토리를 선정하였다. 분석을 위한 연구 모형은 수정 확장된 통합기술 수용이론(Meta-UTAUT)을 기반으로 연구 대상 기술의 특성을 반영하여 공통의 영향 변인을 도출하여 설정하였다. 실증 분석을 위해 설문조사를 진행하였으며 AR 사용자 150명, 스마트 팩토리 사용자 150명을 분석의 대상으로 삼았다. 실증연구 결과는 다음과 같다. 성과기대와 사용 의도, 기술 준비도와 사용 의도 간의 관계는 AR과 스마트 팩토리 모두 유의한 정(+)의 영향을 미치는 것으로 나타났다. 반면, 노력 기대, 사회적 영향, 신뢰성은 AR에 있어서만 사용 의도에 정(+)의 영향을 미치는 것으로 나타났다. 스마트 팩토리에서만 사용 지원이 사용 의도에 정(+)의 유의한 영향을 미쳤다. 인지된 위험 역시 스마트 팩토리에서만 사용 의도에 부(-)의 유의한 영향을 미친 것으로 나타났다. 이러한 연구 결과는 학술적으로는 새로운 기술의 사용도 소비자들이 사용하는 맥락에 따라 영향 요인이 달라진다는 것을 실증적으로 검정 했다는데 의의가 있다고 할 수 있다. 또한 제공하는 기술이나 서비스가 어떠한 맥락에서 이루어지고 있는지를 판단해서 무엇에 우선적으로 집중해야 할 지를 제시한 점에서 실무적인 의의가 있다고 할 수 있다.

근치적 전립선적출술 후 요실금에 대한 케겔운동의 효과: 무작위 대조군 실험연구의 체계적 문헌고찰 (Effect of Kegel Exercise on Urinary Incontinence after Radical Prostatectomy: Systematic Review of Randomized Controlled Trials)

  • 박성희;조윤수;곽미정;이희선;강창범
    • 성인간호학회지
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    • 제25권2호
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    • pp.219-230
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    • 2013
  • Purpose: This study is reviewed of the available literature to identify the evidence of the value of Kegel exercise programs as an intervention to decrease urinary incontinence and the improvement of the quality of life following a radical prostatectomy in localized prostate cancer. Methods: We searched studies of randomized controlled trials that utilized the Kegel exercise programs with patient with a radical prostatectomy. The review was conducted electronic bibliographic database of Ovid-Medline, Embase, Scopus, KoreaMed and NDSL, etc. Of 630 publications identified, seven studies that met the inclusion criteria, and all studies analyzed by meta-analysis. To ensure the quality of the studies, we used Cochrane's Risk of Bias. Results: Kegel exercise helped patient to achieve continence more quickly (after 1, 3, 6, 12 months) than men not using Kegel exercises. Especially, Kegel exercise significantly reduced the development of urinary incontinence at one month after prostatectomy. The effectiveness of Kegel exercise after prostatectomy was found to improve the quality of life at a significant level. Conclusion: Based on available evidence, Kegel exercise that nurses can teach improved the return to continence more than usual care in men with prostatectomy urinary incontinence.

고관절 치환술 후 추나치료 효과: 체계적 문헌고찰 및 메타분석 (Effects of Chuna Manual Therapy after Hip Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials)

  • 이은별;김현지;김채영;안희덕
    • 한방재활의학과학회지
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    • 제32권2호
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    • pp.95-103
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    • 2022
  • Objectives This study was conducted to assess the effect of chuna manual therapy after hip arthroplasty. Methods We searched across 9 electronic databases (PubMed, Cochrane Library, Wangfang data, China National Knowledge Infrastructure [CNKI], Oriental Medicine Advanced Searching Integrated System [OASIS], National Digital Science Library [NDSL], Korean Medical Database [KMBASE], Koreanstudies Information Service System [KISS], Research Information Sharing Service [RISS]) to find randomized controlled clinical trials for chuna manual therapy after hip arthroplasty. Results On inclusion criteria, 11 appropriate studies were included and analyzed. The deep vein thrombosis incidence of the chuna manual therapy group was statistically lower than the conventional treatment group (p=0.0002). Chuna manual therapy significantly improved the Harris hip score compared with conventional treatment (p<0.00001). Also, chuna manual therapy combined with herbal fumigation therapy significantly elevated the hip joint function score of Harris hip score compared with the conventional therapy group (p<0.00001). Conclusions The systematic review showed that chuna manual therapy had significant effects on hip arthroplasty. Nonetheless, considering the high risk of bias and geographic bias, further research with well-designed studies is required to support the effectiveness of chuna manual therapy.